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About 1,508 results

ALLMedicine™ Hypernatremia Center

Research & Reviews  500 results

Safety of Withholding Perioperative Hydrocortisone for Patients With Pituitary Adenomas...
https://doi.org/10.1001/jamanetworkopen.2022.42221
JAMA Network Open; Guo X, Zhang D et. al.

Nov 17th, 2022 - Pituitary adenoma is the second most common primary brain tumor. Perioperative hydrocortisone has been used for decades to avoid postoperative adrenal insufficiency. Recent studies suggest that withholding perioperative hydrocortisone may be safe ...

Admission serum sodium and osmolarity are not associated with the occurrence or outcome...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616514
Journal of Critical Care; Li H, Bihari S et. al.

Nov 12th, 2022 - Previous studies suggested that hypernatremia or hyperosmolarity may have protective effects in lung injury. We hypothesized that hypernatremia and/or hyperosmolarity would prevent ARDS. Retrospective cohort study of all admissions at medical, sur...

Analysis of Electrolyte Abnormalities in Adolescents and Adults and Subsequent Diagnosi...
https://doi.org/10.1001/jamanetworkopen.2022.40809
JAMA Network Open; Hundemer GL, Clarke A et. al.

Nov 9th, 2022 - Eating disorders lead to increased mortality and reduced quality of life. While the acute presentations of eating disorders frequently involve electrolyte abnormalities, it remains unknown whether electrolyte abnormalities may precede the future d...

Fatal overdose from injection of human growth hormone; a case report and review of the ...
https://doi.org/10.1186/s12902-022-01193-2
BMC Endocrine Disorders; Erfanifar A, Mahjani M et. al.

Nov 9th, 2022 - Human growth hormone (HGH) is a categorized as a performance-enhancing substance. HGH has been abused by athletes for doping purposes. We present a first lethal case of HGH acute toxicity. A young-agitated-athlete with a history of somatropin for ...

Trends in tolvaptan prescription and the association between hypernatremia and aging in...
https://doi.org/10.5414/CP204307
International Journal of Clinical Pharmacology and Therap... Uno T, Hosomi K et. al.

Nov 5th, 2022 - To identify the trends in tolvaptan prescription and the association between aging and tolvaptan-induced hypernatremia. A health insurance claims database and a spontaneous adverse drug reaction database were used. Of all patients who had been pre...

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Drugs  15 results see all →

Clinicaltrials.gov  45 results

Efficacy and Safety of Rapid Intermittent Correction Compared With Slow Continuous Correction in Patients With Severe Hypernatremia
https://clinicaltrials.gov/ct2/show/NCT04949139

Aug 24th, 2022 - Hypernatremia is defined as serum sodium (sNa) levels above 145 mmol/L and is caused by abnormalities in water balance, mainly in children, elderly, and critically ill patients. It occurs in 3% of hospitalized patients and in 9% of critically ill ...

Comparison of the Isotonic and Hypotonic Intravenous Maintenance Fluids In Term Newborns: Neofluid Study
https://clinicaltrials.gov/ct2/show/NCT04781361

Aug 3rd, 2022 - Considering the physiological changes in fluid and electrolyte balance and providing proper support are one of the important aspects of neonatal intensive care. Maintenance intravenous fluids are designed to maintain homeostasis when a patient is ...

Effect of Protein Supplementation on Plasma Sodium Levels and Urinary Urea Excretion in Patients With SIAD
https://clinicaltrials.gov/ct2/show/NCT04987385

Jul 29th, 2022 - Hyponatremia (blood sodium <135 mmol/l) is the most frequent electrolyte and fluid disturbance with a prevalence up to 30% in hospitalized patients. The most common etiology of euvolemic hyponatremia is the syndrome of inappropriate antidiuresis (...

Central Sodium Sensing: Implications for Blood Pressure Regulation
https://clinicaltrials.gov/ct2/show/NCT05480722

Jul 29th, 2022 - The prevalence of hypertension is very high in older adults, and a major factor in hypertension is salt sensitivity of blood pressure (BP) and elevated sympathetic nerve activity (SNA). However, we know very little about how the human brain 'sense...

Prevelane and Short Term Outcome of Hypernatremic Dehydration in Children With Acute Gastroenteritis in Sohag University Hospital
https://clinicaltrials.gov/ct2/show/NCT05440162

Jun 30th, 2022 - Hypernatremic dehydration (HND) is a common and potentially life-threatening condition in children. It is defined by a serum level of sodium greater than or equal to 145 mmol/L . HND is a type of acute dehydration constitutes a medical emergency a...

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News  43 results

Electrolyte Disturbances a Harbinger of Eating Disorders?
https://www.medscape.com/viewarticle/984087

Nov 15th, 2022 - Electrolyte abnormalities may serve as a precursor to a future eating disorder diagnosis, a finding that may help pinpoint candidates for screening. Researchers found that adolescents and adults with electrolyte abnormalities on routine outpatient...

FDA Approves Drug for Cisplatin Ototoxicity in Kids With Cancer
https://www.medpagetoday.com/hematologyoncology/othercancers/100845

Sep 21st, 2022 - The FDA has approved sodium thiosulfate (Pedmark) as the first treatment for cisplatin-related ototoxicity in pediatric patients, Fennec Pharmaceuticals announced. The approved indication is to reduce the risk of ototoxicity associated with cispla...

FDA Approves Pedmark for Prevention of Platinum-Induced Ototoxicity in Pediatric Solid Tumors
https://www.onclive.com/view/fda-approves-pedmark-for-prevention-of-platinum-induced-ototoxicity-in-pediatric-solid-tumors

Sep 20th, 2022 - The FDA has approved sodium thiosulfate (Pedmark) to reduce the risk of ototoxicity associated with cisplatin in pediatric patients aged 1 month and older with localized, nonmetastatic solid tumors.1 The efficacy of the product was examined in pe...

Real-World Data Underscore Importance of NTRK Gene Fusions in Tumor Agnostic Therapies
https://www.onclive.com/view/real-world-data-underscore-importance-of-ntrk-gene-fusions-in-tumor-agnostic-therapies

Jul 6th, 2022 - The role of NTRK gene fusions across multiple cancer types have led investigators to confirm the marker in real-world data analyses.1 TRK fusion has become quite famous over the past few years, and we know this is a chromosomal rearrangement tha...

Larotrectinib Continues to Demonstrate High DCR, Elicit Durable Responses in TRK Fusion+ CNS Tumors
https://www.onclive.com/view/larotrectinib-continues-to-demonstrate-high-dcr-elicit-durable-responses-in-trk-fusion-cns-tumors

Jun 5th, 2022 - Larotrectinib (Vitrakvi) continued to produce rapid and durable responses, with a high disease control rate (DCR) and an acceptable toxicity profile in patients with TRK fusion–positive, primary central nervous system (CNS) tumors, according to lo...

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