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About 3,263 results

ALLMedicine™ Hypoparathyroidism Center

Research & Reviews  1,018 results

The parathyroid glands and parathyroid hormone: Insights from PTH gene mutations.
https://doi.org/10.1016/bs.vh.2022.04.004
Vitamins and Hormones; Lee JH, Lee S

Aug 12th, 2022 - Nine mutations have been discovered in the parathyroid hormone (PTH) gene since it was initially sequenced in 1983. An autosomal dominant C18R mutation in the signal peptide was first reported in 1990, followed by an exon skipping mutation, leadin...

Comparison of the robotic bilateral axillo-breast approach and conventional open thyroi...
https://doi.org/10.1089/thy.2022.0242
Thyroid : Official Journal of the American Thyroid Associ... Li C, Gao Y et. al.

Aug 10th, 2022 - Operations for pediatric thyroid nodules are more complicated, and usually lead to longer scars, which may impair life quality in the long term. Bilateral axillo-breast approach (BABA) robotic thyroidectomy (BABA RT) may provide a better alternati...

Usefulness of ICG Angiography-Guided Thyroidectomy for Preserving Parathyroid Function.
https://doi.org/10.1007/s00268-022-06683-x
World Journal of Surgery; Moreno-Llorente P, García-Barrasa A et. al.

Aug 10th, 2022 - Hypoparathyroidism is the most frequent complication after total thyroidectomy and, when permanent, it becomes a severe chronic disease. We assessed the usefulness of indocyanine green (ICG) angiography-guided thyroidectomy to reduce the postopera...

A Trial Investigating the Safety, Tolerability and Efficacy of TransCon PTH Administered Daily in Adults With Hypoparathyroidism
https://clinicaltrials.gov/ct2/show/NCT04701203

Aug 9th, 2022 - During the first 26 weeks of the trial, participants will be randomly assigned to one of two groups: one group will receive TransCon PTH and one group will receive placebo. All subjects will start with a fixed dose of study drug and will be indivi...

Influence of Single Experience with Intraoperative Near-Infrared Autofluorescence on Po...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346384
International Journal of Medical Sciences; Domosławski P, Adamiecki M et. al.

Aug 6th, 2022 - Introduction: Total thyroidectomy has become the most common thyroid procedure. This treatment method results in most postoperative hypocalcemia (PH) and hypoparathyroidism (HPT) cases due to the unwitting removal of the parathyroid glands (PTGs)....

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Guidelines  5 results

Management of immune-related adverse events in endocrine organs induced by immune check...
https://doi.org/10.1507/endocrj.EJ19-0163
Endocrine Journal; Arima H, Iwama S et. al.

Jun 28th, 2019 - Immune checkpoint inhibitors (ICIs) have become a promising treatment for advanced malignancies. However, these drugs can induce immune-related adverse events (irAEs) in several organs, including skin, gastrointestinal tract, liver, muscle, nerve,...

American Thyroid Association Statement on Postoperative Hypoparathyroidism: Diagnosis, ...
https://doi.org/10.1089/thy.2017.0309
Thyroid : Official Journal of the American Thyroid Associ... Orloff LA, Wiseman SM et. al.

Jun 1st, 2018 - Hypoparathyroidism (hypoPT) is the most common complication following bilateral thyroid operations. Thyroid surgeons must employ strategies for minimizing and preventing post-thyroidectomy hypoPT. The objective of this American Thyroid Association...

Diagnosis and treatment of hypoparathyroidism: a position statement from the Brazilian ...
https://doi.org/10.20945/2359-3997000000015
Archives of Endocrinology and Metabolism; Maeda SS, Moreira CA et. al.

Apr 26th, 2018 - Objective To present an update on the diagnosis and treatment of hypoparathyroidism based on the most recent scientific evidence. Materials and methods The Department of Bone and Mineral Metabolism of the Sociedade Brasileira de Endocrinologia e M...

European Society of Endocrinology Clinical Guideline: Treatment of chronic hypoparathyr...
https://doi.org/10.1530/EJE-15-0628
European Journal of Endocrinology; Bollerslev J, Rejnmark L et. al.

Jul 15th, 2015 - Hypoparathyroidism (HypoPT) is a rare (orphan) endocrine disease with low calcium and inappropriately low (insufficient) circulating parathyroid hormone levels, most often in adults secondary to thyroid surgery. Standard treatment is activated vit...

American Thyroid Association statement on optimal surgical management of goiter.
https://doi.org/10.1089/thy.2013.0291
Thyroid : Official Journal of the American Thyroid Associ... Chen AY, Bernet VJ et. al.

Dec 4th, 2013 - Goiter, or benign enlargement of the thyroid gland, can be asymptomatic or can cause compression of surrounding structures such as the esophagus and/or trachea. The options for medical treatment of euthyroid goiter are short-lived and are limited ...

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Drugs  78 results see all →

Clinicaltrials.gov  111 results

A Trial Investigating the Safety, Tolerability and Efficacy of TransCon PTH Administered Daily in Adults With Hypoparathyroidism
https://clinicaltrials.gov/ct2/show/NCT04701203

Aug 9th, 2022 - During the first 26 weeks of the trial, participants will be randomly assigned to one of two groups: one group will receive TransCon PTH and one group will receive placebo. All subjects will start with a fixed dose of study drug and will be indivi...

Safety, Tolerability, and Efficacy of CLTX-305 in Participants With Autosomal Dominant Hypocalcemia (ADH) Type 1
https://clinicaltrials.gov/ct2/show/NCT04581629

Jul 22nd, 2022 - Autosomal dominant hypocalcemia Type 1 is a rare familial genetic form of hypoparathyroidism. Autosomal Dominant Hypocalcemia (ADH) Type 1 is typically passed down from affected parents to their children. This is a Phase 2b open label, dose findin...

Quality of Life Related to Different Treatment Protocols for Post-thyroidectomy Hypoparathyroidism
https://clinicaltrials.gov/ct2/show/NCT03249012

Jul 21st, 2022 - Enrolled patients will be randomized in two treatment groups. In group 1, all patients will receive calcium carbonate and calcitriol in the post-operative period, with standardized weaning. In group 2, patients will be prescribed calcium carbonate...

Efficacy of Vitamin D Treatment in Mortality Reduction Due to COVID-19.
https://clinicaltrials.gov/ct2/show/NCT04621058

Jul 15th, 2022 - HYPOTHESIS: The administration of vitamin D supplements to patients who have a positive diagnosis for SARS-Cov-2, acute pneumonia requiring hospital admission and vitamin D deficiency have a more favourable evolution than subjects not treated with...

Contribution of ICG Angiography in the Detection of Parathyroids and the Prevention of Hypoparathyroidism Post Total Thyroidectomy
https://clinicaltrials.gov/ct2/show/NCT04785443

Jul 8th, 2022 - Hypoparathyroidism is the most common complication after a total thyroidectomy surgery. It is most often transient but can sometimes be permanent when it persists for more than 6 months after surgery. The rates are variable, of the order of 32% fo...

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News  88 results

Near-Infrared Autofluorescence Boosts Thyroidectomy Outcomes
https://www.medscape.com/viewarticle/978991

Aug 10th, 2022 - The study covered in this summary was published on Research Square as a preprint and has not yet been peer reviewed. Key Takeaways In a single-center, case-control study, 134 patients who underwent total thyroidectomy (TT) were compared with patie...

Top strategies for preventing tardive dyskinesia
https://www.mdedge.com/psychiatry/article/251979/movement-disorders/top-strategies-preventing-tardive-dyskinesia
Doug Brunk

Feb 18th, 2022 - LAS VEGAS – In the opinion of Christoph U. Correll, MD, tardive dyskinesia (TD) “has been somewhat forgotten” by psychiatrists because the risk of patients developing the condition is considered to be significantly lower with second-generation ant.

Serotonin Syndrome? Not So Fast, Sherlock
https://www.medscape.com/viewarticle/967782

Feb 15th, 2022 - Mark E. Williams, MD My 72-year-old patient was a new admission to our facility on a Friday afternoon. Donna had a history of bipolar II disorder, anxiety, depression, hypothyroidism, hypoparathyroidism, hypertension, gastric reflux, and collageno...

Hypoparathyroidism Rates Low After Thyroidectomy for Graves Disease
https://www.medscape.com/viewarticle/960909

Oct 14th, 2021 - Dr Carolyn Seib Older people treated for Graves disease with total thyroidectomy in the United States are at low risk of developing hypoparathyroidism, according to results from a large population-based cohort study. "The risk of permanent hypopar...

New Form of Parathyroid Hormone Cuts Need for Conventional Therapy in Chronic Hypoparathyroidism
https://www.medscape.com/viewarticle/958613

Sep 15th, 2021 - NEW YORK (Reuters Health) - In adults with chronic hypoparathyroidism, an investigational prodrug of parathyroid hormone, TransCon PTH, allowed most participants in a small randomized trial to reduce or forgo conventional therapy of vitamin D and ...

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Patient Education  5 results see all →