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About 19,755 results

ALLMedicine™ Hypothyroidism Center

Research & Reviews  5,608 results

Severe autoimmune thyroiditis in transgenic NOD.H2h4 mice expressing interleukin-4 in t...
https://doi.org/10.1089/thy.2022.0448
Thyroid : Official Journal of the American Thyroid Associ... Merakchi K, Djerbib S et. al.

Nov 24th, 2022 - Hashimoto's thyroiditis is a common autoimmune thyroid disorder characterized by thyroid lymphocytic infiltrates and autoreactive antibodies against thyroglobulin (TgAbs) and thyroperoxidase. Final evolution of the disease can lead to hypothyroidi...

Abnormal uterine bleeding patterns determined through menstrual tracking among particip...
https://doi.org/10.1016/j.ajog.2022.10.029
American Journal of Obstetrics and Gynecology; Zhang CY, Li H et. al.

Nov 23rd, 2022 - Use of menstrual tracking data to understand abnormal bleeding patterns has been limited because of lack of incorporation of key demographic and health characteristics and confirmation of menstrual tracking accuracy. This study aimed to identify a...

Maternal hypothyroidism and adverse outcomes of pregnancy.
https://doi.org/10.1111/cen.14853
Clinical Endocrinology; Knøsgaard L, Andersen S et. al.

Nov 23rd, 2022 - Hypothyroidism has been associated with pregnancy complications, but uncertainty prevail regarding the severity and the role of thyroid autoimmunity. This study aimed to evaluate adverse pregnancy outcomes by exposure to maternal hypothyroidism an...

Levothyroxine: Conventional and novel drug delivery formulations.
https://doi.org/10.1210/endrev/bnac030
Endocrine Reviews; Liu H, Li W et. al.

Nov 23rd, 2022 - Despite the fact that levothyroxine is one of the most prescribed medications in the world, its bioavailability has been reported to be impaired by many factors, including interfering drugs or foods and concomitant diseases, and persistent hypothy...

Case 308: Van Wyk-Grumbach Syndrome.
https://doi.org/10.1148/radiol.211119
Radiology Kandasamy D, Malik R et. al.

Nov 22nd, 2022 - An 11-year-old girl presented to the pediatric gastroenterology outpatient department of our institution with gradually increasing painless abdominal distention. The distention started 2 years earlier and was not associated with any other constitu...

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Guidelines  14 results

Evidence-Based Use of Levothyroxine/Liothyronine Combinations in Treating Hypothyroidis...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8035928
Thyroid : Official Journal of the American Thyroid Associ... Jonklaas J, Bianco AC et. al.

Dec 6th, 2020 - Background: Fourteen clinical trials have not shown a consistent benefit of combination therapy with levothyroxine (LT4) and liothyronine (LT3). Despite the publication of these trials, combination therapy is widely used and patients reporting ben...

Congenital Hypothyroidism: A 2020-2021 Consensus Guidelines Update-An ENDO-European Ref...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001676
Thyroid : Official Journal of the American Thyroid Associ... van Trotsenburg P, Stoupa A et. al.

Dec 5th, 2020 - Background: An ENDO-European Reference Network (ERN) initiative was launched that was endorsed by the European Society for Pediatric Endocrinology and the European Society for Endocrinology with 22 participants from the ENDO-ERN and the two societ...

Thyroid Disease in Pregnancy: ACOG Practice Bulletin, Number 223.
https://doi.org/10.1097/AOG.0000000000003893
Obstetrics and Gynecology;

May 23rd, 2020 - Both thyrotoxicosis and hypothyroidism are associated with adverse pregnancy outcomes. There also is concern about the effect of overt maternal thyroid disease on fetal development. In addition, medications that affect the maternal thyroid gland c...

Thyroid hormones treatment for subclinical hypothyroidism: a clinical practice guideline.
https://doi.org/10.1136/bmj.l2006
BMJ (Clinical Research Ed.); Bekkering GE, Agoritsas T et. al.

May 16th, 2019 - What are the benefits and harms of thyroid hormones for adults with subclinical hypothyroidism (SCH)? This guideline was triggered by a recent systematic review of randomised controlled trials, which could alter practice. Current guidelines tend t...

Palliative and supportive care in head and neck cancer: United Kingdom National Multidi...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873917
The Journal of Laryngology and Otology; Cocks H, Ah-See K et. al.

Nov 15th, 2016 - This is the official guideline endorsed by the specialty associations involved in the care of head and neck cancer patients in the UK. It provides recommendations on the assessments and interventions for this group of patients receiving palliative...

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Drugs  535 results see all →

Clinicaltrials.gov  326 results

The Relationship Between Serum rT3 Concentrations, T3/T4 Ratio, and Symptoms/Quality of Life in Treated Hypothyroid Patients
https://clinicaltrials.gov/ct2/show/NCT05015725

Oct 12th, 2022 - Rationale: L-thyroxin (T4) substitution is the mainstay of treatment for hypothyroidism irrespective of disease origin. In a subset of patients with hypothyroidism however an inadequate peripheral T4->T3 conversion is hypostasized by some authors....

Use of Tirosint®-SOL or Tablet Formulations of Levothyroxine in Pediatric Patients With Congenital Hypothyroidism (CH)
https://clinicaltrials.gov/ct2/show/NCT05228184

Oct 10th, 2022 - Newly diagnosed neonates will be randomly assigned to start therapy with LT4 at the initial dose recommended by the Standard of Care (SOC). Infants already on LT4 therapy will continue at the same daily dose within the randomly assigned treatment ...

Personalized Treatment in Thyroid Disorders
https://clinicaltrials.gov/ct2/show/NCT03517579

Oct 6th, 2022 - Radioiodine treatment for thyroid disorders represented an early example of individualized medicine. Since its introduction 80 years ago, the therapeutic I-131 dosage has usually been tailored to individual patient requirements based on the uptake...

Evaluation of Patients With Thyroid Disorders
https://clinicaltrials.gov/ct2/show/NCT00001159

Oct 4th, 2022 - Patients with thyroid function abnormalities (hyperthyroidism, hypothyroidism) are studied and treated in this protocol. Patients undergo routine history and physical examination, standard endocrine blood and urine tests, a standard TRH test, thyr...

Investigation of the Efficacy of Virtual Reality Mediated Neurodynamic Exercises in Carpal Tunnel Syndrome
https://clinicaltrials.gov/ct2/show/NCT05563909

Oct 3rd, 2022 - Carpal tunnel syndrome (CTS) is the most common nerve entrapment syndrome. It occurs as a result of compression of the median nerve as it passes through a restricted osteofibrous canal in the wrist. Known as the carpal tunnel, this canal contains ...

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News  1,313 results

Even Subclinical Hyperthyroidism May Weaken Bones
https://www.medpagetoday.com/endocrinology/thyroid/101664

Nov 9th, 2022 - Subclinical hyperthyroidism may be an independent risk factor for fractures, a community-based cohort study found. In the analysis of nearly 11,000 middle-age individuals, having subclinical hyperthyroidism was tied with a 34% higher risk for subs...

Does Subclinical Hyperthyroidism Raise Fracture Risk?
https://www.medscape.com/viewarticle/983771

Nov 9th, 2022 - People with subclinical hyperthyroidism are at 34% greater risk of experiencing a fracture compared with those with normal thyroid function, new research shows. The finding, from a study of nearly 11,000 middle-aged men and women followed for a me...

Regorafenib Plus Ipilimumab and Nivolumab Shows Intriguing Activity in MSS mCRC
https://www.onclive.com/view/regorafenib-plus-ipilimumab-and-nivolumab-shows-intriguing-activity-in-mss-mcrc

Nov 8th, 2022 - Regorafenib (Stivarga) plus ipilimumab (Yervoy) and nivolumab (Opdivo) led to encouraging survival and responses in approximately half of patients with microsatellite stable (MSS), non–liver metastatic colorectal cancer (mCRC) who progressed on pr...

Pembrolizumab Plus Cabozantinib Improves ORR in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
https://www.onclive.com/view/pembrolizumab-plus-cabozantinib-improves-orr-in-recurrent-metastatic-head-and-neck-squamous-cell-carcinoma

Nov 8th, 2022 - A doublet regimen comprised of pembrolizumab (Keytruda) and cabozantinib (Cabometyx) elicited encouraging responses in patients with recurrent metastatic head and neck squamous cell carcinoma (HNSCC), meeting the primary end point of a phase 2 tri...

Luspatercept Improves Transfusion Independence in Very Low– to Intermediate-Risk MDS
https://www.onclive.com/view/luspatercept-improves-transfusion-independence-in-very-low-to-intermediate-risk-mds

Oct 31st, 2022 - Luspatercept-aamt (Reblozyl) generated a highly statistically significant and clinically meaningful improvement in red blood cell (RBC) transfusion independence with concurrent hemoglobin increase compared with epoetin alfa in patients with very l...

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Patient Education  106 results see all →