About 5,675 results

ALLMedicine™ Metabolic Acidosis Center

Research & Reviews  1,880 results

Understanding the risk factors for adverse events during exchange transfusion in neonat...
BMC Pediatrics; Zhu S, Zhou L et. al.

Oct 1st, 2022 - To understand the risk factors associated with adverse events during exchange transfusion (ET) in severe neonatal hyperbilirubinemia. We conducted a retrospective study of infants with hyperbilirubinemia who underwent ET within 30 days of birth fr...

Metabolic Acidosis-Is It the Elephant in the Room?
Advances in Chronic Kidney Disease; Narayanan M, Wesson D

Sep 30th, 2022 - Metabolic Acidosis-Is It the Elephant in the Room?|2022|Narayanan M,Wesson D,|

Review of Clinical Disorders Causing Metabolic Acidosis.
Advances in Chronic Kidney Disease; Emmett M

Sep 30th, 2022 - The various mechanisms responsible for the development of metabolic acidosis are briefly reviewed, and the metabolic acidoses are categorized both by mechanism and by the presence or absence of an increased anion gap. When a diagnosis of metabolic...

The Importance of Recognizing and Addressing the Spectrum of Acid Stress.
Advances in Chronic Kidney Disease; Wesson DE

Sep 30th, 2022 - Acid accumulation sufficient to reduce plasma bicarbonate concentration, thereby recognized as chronic metabolic acidosis, harms bones and muscles and appears to enhance progression of CKD. Evolving evidence supports that progressive acid accumula...

Dietary Contributions to Metabolic Acidosis.
Advances in Chronic Kidney Disease; Frassetto L, Remer T et. al.

Sep 30th, 2022 - Eating a net acid-producing diet can produce an "acid stress" of severity proportional to the diet net acid load, as indexed by the steady-state renal net acid excretion rate. Depending on how much acid or base is ingested or produced from endogen...

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Guidelines  1 results

Evaluation and management of small-bowel obstruction: an Eastern Association for the Su...
The Journal of Trauma and Acute Care Surgery; Maung AA, Johnson DC et. al.

Dec 27th, 2012 - Small-bowel obstruction (SBO) represents as many as 16% of surgical admissions and more than 300,000 operations annually in the United States. The optimal strategies for the diagnosis and management of SBO continue to evolve secondary to advances ...

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Drugs  90 results see all →

Clinicaltrials.gov  169 results

Cancer in Inherited Bone Marrow Failure Syndromes

Sep 28th, 2022 - Background: A prospective cohort of Inherited Bone Marrow Failure Syndrome (IBMFS) will provide new information regarding cancer rates and types in these disorders. Pathogenic variant(s) in IBMFS genes are relevant to carcinogenesis in sporadic ca...

Evaluation of Effect of TRC101 on Progression of Chronic Kidney Disease in Subjects With Metabolic Acidosis

Sep 23rd, 2022 - This is a randomized, double-blind, placebo-controlled trial. Eligible subjects will be randomized in a 1:1 ratio to TRC101 or placebo. The primary endpoint of the study will be progression of renal disease, defined by time to first occurrence of ...

Incidence of Acute Kidney Injury and Mortality in Critically Ill Patients: Urinary Chloride as a Prognostic Marker

Sep 16th, 2022 - Acute kidney injury (AKI) is characterized by a rapid decrease in renal function. It is frequent in hospitalized patients and its incidence is higher in critically ill patients. It is associated with high rates of morbidity and mortality. AKI affe...

Near Infrared Spectroscopy in Patients Undergoing Robotic Assisted Laparoscopic Surgery in the Trendelenburg Position

Sep 15th, 2022 - Some robotic endoscopic surgeries require a steep Trendelenburg position and a carbon dioxide pneumoperitoneum. This minimally invasive approach has the advantages of less postoperative pain, shorter hospital stay and faster recovery. After prolon...

Clinical Evaluation of a Point of Care (POC) Assay to Identify Phenotypes in the Acute Respiratory Distress Syndrome

Sep 13th, 2022 - Acute respiratory distress syndrome (ARDS) is an inflammatory condition that results in severe respiratory failure and the need for mechanical ventilation. It is a syndrome with significant global burden and accounts for approximately 24% of mecha...

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News  130 results

Is bicarbonate therapy effective in preventing CKD progression?
MDedge Family Medicine; Haris Ahmad, DO, Theresa Wertin, MD et. al.

Apr 13th, 2022 - Evidence summary Bicarbonate therapy demonstrates benefit in 2 meta-analyses Two recent meta-analyses evaluated studies of bicarbonate therapy in patients with CKD, and both found benefit. 1,2 A 2020 meta-analysis included 15 RCTs (N = 2445) of adu.

Shortness of breath and abdominal pain

Jan 19th, 2022 - On the basis of the patient's history and clinical presentation, the likely diagnosis is ketosis-prone diabetes (KPD) type 2. KPD is widely thought of as an atypical diabetes syndrome, though some groups consider it to be a common clinical present.

Comparison of Adverse Events With Vancomycin Diluted in Normal Saline vs Dextrose 5%
Robert C. Ross, PharmD, Bridgette A. Kelly, PharmD et. al.

Oct 8th, 2021 - Vancomycin is a widely used IV antibiotic due to its broad-spectrum of activity, bactericidal nature, and low rates of resistance; however, adverse effects (AEs), including nephrotoxicity, are commonly associated with its use. 1 The vancomycin ther.

Albuterol, Acidosis, and Aneurysms
Lucy Ma, MD, Christopher Russo et. al.

May 12th, 2021 - An 88-year-old male veteran with a medical history of chronic obstructive pulmonary disease (COPD) on home oxygen, chronic alcohol use, squamous cell carcinoma of the lung status after left upper lobectomy, and a 5. 7 cm thoracic aortic aneurysm wa.

Farxiga Gets FDA Greenlight for CKD

Apr 30th, 2021 - FDA expanded the indication for dapagliflozin (Farxiga) into chronic kidney disease (CKD). The drug, which first entered the market for type 2 diabetes in 2014, was approved to reduce the risk of kidney function decline, kidney failure, cardiovasc...

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