ALLMedicine™ Rattlesnake Envenomation Center

Mar 11th, 2021 - Anavip (F(ab')2AV) is a lyophilized F(ab')2 immunoglobulin fragment derived from horses immunized with venom from Bothrops asper and Crotalus durissus. It was approved by the FDA in 2015 for treatment of North American rattlesnake envenomation but...

Dec 9th, 2020 - Crotalidae envenomation has been managed successfully in emergency departments across the world with antivenom. Over the years, antivenom has evolved and newer agents have been studied with the possibility of eliminating maintenance antivenom ther...

Aug 8th, 2020 - Two antivenoms are available for rattlesnake envenomations in the U.S., Fab (CroFab®, BTG, UK), and F(ab')2 (Anavip®, Bioclon, Mexico) antivenom (AV) with F(ab')2AV released in October 2018. The F(ab')2AV Phase 3 comparative clinical trial demonst...

Jun 8th, 2020 - The use of Fab antivenom (Crotalidae Polyvalent Immune Fab (Ovine) (CroFab); Boston Scientific) against North American Crotalidae envenomation is associated with the development of late- (≥4 days post-envenomation), new-onset of hematological abno...

Dec 30th, 2019 - The dusky pigmy rattlesnake (Sistrurus miliarius barbouri) is a pit viper (Crotalidae family) along with diamondback rattlesnakes, water moccasins, and copperheads. Although it is a small snake, it is responsible for envenomations requiring hospit...

Mar 11th, 2021 - Anavip (F(ab')2AV) is a lyophilized F(ab')2 immunoglobulin fragment derived from horses immunized with venom from Bothrops asper and Crotalus durissus. It was approved by the FDA in 2015 for treatment of North American rattlesnake envenomation but...

Dec 9th, 2020 - Crotalidae envenomation has been managed successfully in emergency departments across the world with antivenom. Over the years, antivenom has evolved and newer agents have been studied with the possibility of eliminating maintenance antivenom ther...

Aug 8th, 2020 - Two antivenoms are available for rattlesnake envenomations in the U.S., Fab (CroFab®, BTG, UK), and F(ab')2 (Anavip®, Bioclon, Mexico) antivenom (AV) with F(ab')2AV released in October 2018. The F(ab')2AV Phase 3 comparative clinical trial demonst...

Jun 8th, 2020 - The use of Fab antivenom (Crotalidae Polyvalent Immune Fab (Ovine) (CroFab); Boston Scientific) against North American Crotalidae envenomation is associated with the development of late- (≥4 days post-envenomation), new-onset of hematological abno...

Dec 30th, 2019 - The dusky pigmy rattlesnake (Sistrurus miliarius barbouri) is a pit viper (Crotalidae family) along with diamondback rattlesnakes, water moccasins, and copperheads. Although it is a small snake, it is responsible for envenomations requiring hospit...

Nov 5th, 2019 - Antivenom Therapy Crotalidae polyvalent immune fab is an antivenom comprised of purified, sheep-derived fab IgG fragments and was approved by the US Food and Drug Administration in 2000 for the treatment of North American crotalid envenomation. 12,.