ALLMedicine™ Hypothermia Center

Feb 4th, 2023 - Mild hypothermia, 32-35°C, reduces infarct size in experimental studies, potentially mediating reperfusion injuries, but human trials have been ambiguous. To elucidate the cardioprotective mechanisms of mild hypothermia, we analyzed cardiac perfor...

Feb 4th, 2023 - Rewarming is a recommended therapy during the resuscitation of hypothermic patients with hemorrhagic shock. In experimental models, however, it increases inflammatory response and mortality. Although microcirculation is potential target of inflamm...

Feb 3rd, 2023 - To assess variability in continuation of antiseizure medication (ASM) at discharge and to evaluate if continuation of ASM at discharge is associated with death or disability among infants with hypoxic-ischaemic encephalopathy (HIE) and seizures. R...

Feb 2nd, 2023 - Spreading depolarizations (SDs) have been linked to infarct volume expansion following ischemic stroke. Therapeutic hypothermia provides a neuroprotective effect after ischemic stroke. This study aimed to evaluate the effect of hypothermia on the ...

Feb 2nd, 2023 - Recommendations made by several scientific bodies advocate for adoption of evidence-based interventions during the first 60 min of postnatal life, also known as the 'Golden Hour', to better support the fetal-to-neonatal transition. Implementation ...

Feb 9th, 2022 - The aim of these guidelines is to provide evidence‑based guidance for temperature control in adults who are comatose after resuscitation from either in-hospital or out-of-hospital cardiac arrest, regardless of the underlying cardiac rhythm. These ...

Jan 23rd, 2020 - Severe traumatic brain injury (TBI) is associated with high rates of death and disability. As a result, the revised guidelines for the management of pediatric severe TBI address some of the previous gaps in pediatric TBI evidence and management st...

Nov 20th, 2019 - To provide guidance to clinicians, the Wilderness Medical Society convened an expert panel to develop evidence-based guidelines for the out-of-hospital evaluation and treatment of victims of accidental hypothermia. The guidelines present the main ...

Sep 22nd, 2018 - This Enhanced Recovery After Surgery (ERAS) Guideline for perioperative care in cesarean delivery will provide best practice, evidenced-based, recommendations for preoperative, intraoperative, and postoperative phases with, primarily, a maternal f...

Jun 1st, 2018 - Inspired by the Choosing Wisely initiative, a group of pediatric anesthesiologists representing the German Working Group on Paediatric Anaesthesia (WAKKA) coined and agreed upon 10 concise positive ("dos") or negative ("don'ts") evidence-based rec...

Jan 30th, 2023 - Neonatal hypoxic-ischemic encephalopathy (HIE) refers to brain injury resulting from reduced blood and oxygen flow to a baby's brain near the time of birth. HIE affects up to 12,000 newborns each year in the U.S. Half of affected infants have a ba...

Jan 30th, 2023 - Undesirable perioperative hypothermia (UPH) is a decrease in the core body temperature, expressed as the temperature of the blood and internal organs, below 36°C. UPH is an important complication of -anesthesia- and surgery and can occur during th...

Jan 27th, 2023 - This pilot intervention trial will assess the feasibility of a live consultation between community hospital providers and tertiary care providers employing a novel teleconsult platform, Maine Neonatal Encephalopathy Teleconsult (Maine NET), on the...

Jan 27th, 2023 - A database of over 1200 patients will be created by the retrospective capture of the following data in UZ Leuven database: Injury mechanisms data: In order to create a map of injury patterns, severity and criteria that allow for identifying which ...

Jan 26th, 2023 - Management of neonatal pain and sedation often includes opioid therapy. A growing body of evidence suggests long-term harm associated with neonatal opioid exposure. Providing optimal sedation while neonates are undergoing therapeutic hypothermia (...

Feb 2nd, 2023 - Therapeutic hypothermia of donors didn't preserve kidney function as well as machine perfusion of the organ during cold storage, a randomized trial found. Compared with kidneys pumped with a non-oxygenated, cold dialysate after removal, those obta...

Dec 19th, 2022 - Congenital hypothyroidism is one of the most common preventable causes of intellectual disabilities worldwide, but newborn screening has not been established in all countries. Additionally, screening alone is not enough to prevent adverse outcomes.

Dec 8th, 2022 - Bathing in cold water or ice may cut "bad" body fat and reduce the risk of disorders such as diabetes, but other claims of health benefits are less defined, according to researchers from the Arctic University of Norway and the University Hospital ...

Nov 11th, 2022 - The US Food and Drug Administration (FDA) is alerting healthcare professionals about the special management required for opioid overdoses tainted with xylazine, an animal tranquilizer known on the street as tranq, tranq dope, sleep-cut, Philly dop...

Oct 4th, 2022 - FDA advised that generic lots of atenolol and clopidogrel (Plavix) are under recall due to a label mix-up by manufacturer Golden State Medical Supply. LivaNova's LifeSPARC advanced circulatory support system has its controller component under clas...