×
About 660 results

ALLMedicine™ Prurigo Nodularis Center

Research & Reviews  189 results

Phase 3 prurigo nodularis trial shows positive results for nemolizumab
https://www.mdedge.com/dermatology/article/261918/medical-dermatology/phase-3-prurigo-nodularis-trial-shows-positive
Doug Brunk

Mar 22nd, 2023 - NEW ORLEANS – Nemolizumab monotherapy for 16 weeks improved itch, skin lesions, and sleep disturbances in adults with prurigo nodularis (PN), results from a phase 3 trial demonstrated. Nemolizumab is a first-in-class investigational monoclonal ant.

Effectiveness of Dupilumab in Pediatric Patient With Prurigo Nodularis-Like Atopic Derm...
https://doi.org/10.1089/derm.2022.29008.yyi
Dermatitis : Contact, Atopic, Occupational, Drug; Yiling Y, Ali K et. al.

Mar 15th, 2023 - Effectiveness of Dupilumab in Pediatric Patient With Prurigo Nodularis-Like Atopic Dermatitis.|2023|Yiling Y,Ali K,Jiayang D,Qiu Y,Kai G,|

A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Prurigo Nodularis (PN)
https://clinicaltrials.gov/ct2/show/NCT05764161

Mar 10th, 2023 - The study comprises of a 12 week double-blind, vehicle-controlled (DBVC) treatment period, followed by a 40 week open label extension period, and 30 day safety follow-up period During the double blind period, all PN-affected areas identified at ba...

A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Participants With Prurigo Nodularis (PN)
https://clinicaltrials.gov/ct2/show/NCT05755438

Mar 6th, 2023 - The study comprises of a 12 week double-blind, vehicle-controlled (DBVC) treatment period, followed by a 40 week open label extension period, and 30 day safety follow-up period During the double blind period, all PN-affected areas identified at ba...

Failure of Dupilimab With Severe Prurigo Nodularis That Responded Well to Abrocitinib.
https://doi.org/10.1089/derm.2022.0065
Dermatitis : Contact, Atopic, Occupational, Drug; Vander Does A, Yosipovitch G

Feb 28th, 2023 - Failure of Dupilimab With Severe Prurigo Nodularis That Responded Well to Abrocitinib.|2023|Vander Does A,Yosipovitch G,|

see more →

Clinicaltrials.gov  26 results

A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Prurigo Nodularis (PN)
https://clinicaltrials.gov/ct2/show/NCT05764161

Mar 10th, 2023 - The study comprises of a 12 week double-blind, vehicle-controlled (DBVC) treatment period, followed by a 40 week open label extension period, and 30 day safety follow-up period During the double blind period, all PN-affected areas identified at ba...

A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Participants With Prurigo Nodularis (PN)
https://clinicaltrials.gov/ct2/show/NCT05755438

Mar 6th, 2023 - The study comprises of a 12 week double-blind, vehicle-controlled (DBVC) treatment period, followed by a 40 week open label extension period, and 30 day safety follow-up period During the double blind period, all PN-affected areas identified at ba...

A Study to Assess Change in Disease Activity in Adolescents and Adults With Moderate to Severe Prurigo-type Atopic Dermatitis in Japan Who Are Treated With Oral Upadacitinib
https://clinicaltrials.gov/ct2/show/NCT05451316

Feb 27th, 2023 - Atopic dermatitis (AD) is a skin condition that may cause a rash and itching due to inflammation of the skin. Around one-third of patients with AD have had at least 1 incidence of prurigo nodularis (PN), which is characterized by intense, persiste...

Study to Assess the Efficacy, Safety, and Tolerability of Vixarelimab in Reducing Pruritus in Prurigo Nodularis
https://clinicaltrials.gov/ct2/show/NCT03816891

Feb 8th, 2023 - This is a Phase 2a/b randomized, double-blind, placebo-controlled study to investigate the efficacy, safety, tolerability, PK and immunogenicity of Vixarelimab administered subcutaneously (SC) in subjects with prurigo nodularis experiencing prurit...

Benralizumab in Chronic Prurigo - Investigating Clinical Efficacy (BICPIC)
https://clinicaltrials.gov/ct2/show/NCT05528913

Feb 8th, 2023 - Chronic Prurigo (CPG) is a skin disease of unknown incidence and prevalence that can occur in all age groups including children, but which is most prevalent in elderly people. CPG was defined as a distinct disease in 2018 by the Task Force Pruritu...

see more →

News  49 results

Phase 3 prurigo nodularis trial shows positive results for nemolizumab
https://www.mdedge.com/dermatology/article/261918/medical-dermatology/phase-3-prurigo-nodularis-trial-shows-positive
Doug Brunk

Mar 22nd, 2023 - NEW ORLEANS – Nemolizumab monotherapy for 16 weeks improved itch, skin lesions, and sleep disturbances in adults with prurigo nodularis (PN), results from a phase 3 trial demonstrated. Nemolizumab is a first-in-class investigational monoclonal ant.

Pruritic rash on arms and legs
https://www.mdedge.com/atopic-dermatitis-challenge-center/article/261037/atopic-dermatitis/pruritic-rash-arms-and-legs

Feb 5th, 2023 - Atopic dermatitis (AD) is one of the most common chronic, inflammatory skin diseases encountered by dermatologists. AD is characterized by pruritus and a chronic course of exacerbations and remissions.

Dupilumab Gets First FDA-Approved Indication for Prurigo Nodularis
https://www.medpagetoday.com/dermatology/generaldermatology/100967

Sep 29th, 2022 - The FDA has approved dupilumab (Dupixent) as the first treatment with an indication for prurigo nodularis, Sanofi and Regeneron announced. A chronic inflammatory skin condition affecting about 75,000 Americans, prurigo nodularis causes persistent ...

FDA Approves Dupilumab for Treatment of Prurigo Nodularis
https://www.medscape.com/viewarticle/981630

Sep 29th, 2022 - The Food and Drug Administration has approved dupilumab for treating adults with prurigo nodularis, the first treatment approved for this indication, according to a press release from the manufacturers. Recent studies of dupilumab (Dupixent), whic...

Dupilumab Offers 'Clinically Meaningful' Improvements in Prurigo Nodularis
https://www.medscape.com/viewarticle/980511

Sep 9th, 2022 - Patients with prurigo nodularis (PN) who had severe itch and high lesion counts and whose condition was inadequately controlled with prior therapies experienced significant improvements with dupilumab (Dupixent), indicate results from the phase 2 ...

see more →