ALLMedicine™ Crohn Disease Center

Jul 28th, 2021 - CD38 is a cell surface receptor capable of generating calcium-mobilizing second messengers. It has been implicated in host defense and cancer biology, but signaling mechanisms downstream of CD38 remain unclear. Mutations in LRRK2 (leucine-rich rep...

Jul 23rd, 2021 - Cutaneous intestinal either metaplasia or ectopia has mostly been described around intestinal stomas or in patients with Crohn disease. In this study, we described a unique case of cutaneous metaplasia on the elbow of a 25-year-old man who had a c...

Jul 17th, 2021 - A randomized, open-label, controlled clinical trial was designed to assess the effectiveness of a motivational intervention based on the 5 R's model (relevance, risks, rewards, roadblocks, and repetition) delivered by specialized inflammatory bowe...

Jul 11th, 2021 - Conventional treatment for Crohn disease (CD) in pregnancy includes mesalamine, thiopurine, and anti-tumor necrosis factor (TNF)-α agents. However, women may abstain because of complications, nonresponse, or potential adverse outcomes. Peptide-bas...

Jun 22nd, 2021 - Infliximab (INX) has been approved for treating Crohn disease (CD) for many years, showing promis-ing efficacy in the clinic. However, the efficacy of the drug and the prognosis of CD vary significantly with dif-ferent locations of disease patholo...

May 7th, 2020 - Three common clinical scenarios involving use of imaging in Crohn disease are covered. These include the initial evaluation of Crohn disease when the diagnosis has not been previously established, the evaluation for anticipated exacerbation of kno...

Mar 28th, 2019 - Very early onset inflammatory bowel disease (VEO-IBD) is defined as disease presenting before the age of 6. These children require a tailored imaging approach because conventional imaging studies can be difficult to perform at such a young age. Un...

Mar 8th, 2017 - The incidence of Crohn disease (CD) has been increasing and surgery needs to be contemplated in a substantial number of cases. The relevant advent of biological treatment has changed but not eliminated the need for surgery in many patients. Despit...

May 6th, 2020 - Over 1 million people suffer from IBD in the United States. Although the exact pathogenesis is unclear, IBD results from an inappropriate inflammatory response to intestinal microbes which is influenced by the environment in a genetically suscepti...

Jan 13th, 2020 - VWF is a high-molecular-weight multimeric glycoprotein, synthesized and released by vascular endothelial cells and megakaryocytes that play an important role in platelet-endothelial cell interaction and stabilizing the factor VIII (FVIII) coagulat...

Dec 10th, 2019 - Crohn disease (CD) is an idiopathic, chronic, relapsing and remitting inflammatory condition of the gastrointestinal tract with a high risk for complications and need for surgical interventions, particularly in children. Immunomodulators and biolo...

Oct 2nd, 2019 - The aim of this study will be to show a decrease in postoperative morphine consumption by the practice of perioperative self-hypnosis in patients undergoing laparoscopic ileo-caecal resection for Crohn's disease

Mar 11th, 2019 - Crohn disease is an inflammatory chronic disease of the bowel the complex physiopathology of which brings in immunological, genetic and environmental factors. At present, the appeal to biotherapics anti-TNFa (infliximab and adalimumab) or anti-IL-...

Jun 3rd, 2021 - Clinical practice guidelines on the management of emergent inflammatory bowel disease by the World Society of Emergency Surgery and the American Association for the Surgery of Trauma were published in May 2021 in the World Journal of Emergency Sur...

Jun 3rd, 2021 - Clinical practice guidelines on the management of emergent inflammatory bowel disease by the World Society of Emergency Surgery and the American Association for the Surgery of Trauma were published in May 2021 in the World Journal of Emergency Sur...

Jan 5th, 2021 - A diagnosis of atopic dermatitis in individuals ages 15 years or older, compared with controls without atopic dermatitis, was nearly twice as likely to be associated with autoimmune disease, in a case control study derived from Swedish national he...

Jul 28th, 2020 - In July 2020, the American Society of Colon and Rectal Surgeons published clinical practice guidelines on the surgical management of Crohn disease.[1] Medically refractory disease Surgery should be considered for patients in whom the response to m...

Apr 17th, 2020 - The patient's signs and symptoms should raise suspicion for inflammatory bowel disease, due to its chronic and relapsing character. Physical examination shows extraintestinal manifestations of Crohn disease. Fistulization between abdominal structu...