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About 270 results

ALLMedicine™ Unconjugated Hyperbilirubinemia Center

Research & Reviews  103 results

Pernicious Anemia Differential Diagnoses
https://emedicine.medscape.com/article/204930-differential

May 16th, 2022 - Diagnostic Considerations By definition, pernicious anemia refers specifically to vitamin B12 deficiency resulting from a lack of production of intrinsic factor (IF) in the stomach. However, vitamin B12 absorption is a complex process, and other c...

Light-Emitting Diode (LED) Phototherapy versus Non-LED Phototherapy Devices for Hyperbi...
https://doi.org/10.1055/a-1827-7607
American Journal of Perinatology; Novoa RH, Huamán K et. al.

Apr 19th, 2022 - This review was conducted to evaluate the efficacy of light-emitting diode (LED) phototherapy as compared to the conventional phototherapy in neonates with unconjugated hyperbilirubinemia and their adverse effects. We searched the following databa...

Genetic testing of UGT1A1 in the diagnosis of Gilbert syndrome: The discovery of seven ...
https://doi.org/10.1002/mgg3.1958
Molecular Genetics & Genomic Medicine; Gu L, Han Y et. al.

Apr 16th, 2022 - Genetic testing of UGT1A1 was used to facilitate the diagnosis of Gilbert syndrome, and analyze the distribution features of pathogenic variants in the Chinese population. DNA was extracted from whole blood samples of patients with unconjugated hy...

Successful haploidentical hematopoietic stem cell transplantation (HSCT) and durable en...
https://doi.org/10.1111/petr.14278
Pediatric Transplantation; Chan WYK, Chan NCN et. al.

Apr 10th, 2022 - Hemoglobin (Hb) Hammersmith is a rare form of unstable β-chain hemoglobinopathy causing hemolytic anemia. This rare event led to a more serious transfusion-dependent phenotype in a patient. It was successfully cured by haploidentical hematopoietic...

Can serum albumin level affect the transcutaneous bilirubinometry in term neonates?
https://doi.org/10.3233/NPM-210958
Journal of Neonatal-perinatal Medicine; Kumar D, Kumar D

Mar 29th, 2022 - Jaundice is the quite common benign condition in neonates, but due to its potential toxicity, neonates must be monitored. This study was aimed to evaluate the effect of serum albumin level on the transcutaneous bilirubin (TcB) measurements in term...

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Clinicaltrials.gov  2 results

A Pilot Study of Moderate Hyperbilirubinemia in Type 1 Diabetes Mellitus
https://clinicaltrials.gov/ct2/show/NCT01421355

Jul 21st, 2014 - Diabetes mellitus (DM) is associated with a markedly increased risk of both macro- and microvascular disease. Excess pro-oxidants and insufficient antioxidants each contributes to oxidant stress in DM. Oxidant stress induces endothelial dysfunctio...

Orlistat Treatment of Crigler-Najjar Disease
https://clinicaltrials.gov/ct2/show/NCT00461799

Apr 18th, 2007 - Unconjugated hyperbilirubinemia in Crigler-Najjar (CN) disease is conventionally treated with phototherapy and/or phenobarbital. Life-long daily phototherapy has considerable disadvantages. Main problems are a decreasing efficacy with age and a pr...

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News  3 results

FDA Asks Geron to Halt Imetelstat Development
https://www.onclive.com/view/fda-asks-geron-to-halt-imetelstat-development

Dec 4th, 2020 - John Chip Scarlett, MD The FDA has placed a full clinical hold on the development of the investigational telomerase inhibitor imetelstat following concerns over consistent low-grade liver function test (LFT) abnormalities, according to a verbal n...

Why Biliary Atresia Demands Our Respect
https://www.staging.medscape.com/viewarticle/935660

Aug 19th, 2020 - As I listened to our fellow present the case of a 5-month-old infant referred for evaluation of persistent jaundice, painful memories of several similar cases flashed by, causing me to ask, "Is this another late diagnosis of biliary atresia?" This...

Neonatal hyperbilirubinemia: An evidence-based approach
https://www.mdedge.com/familymedicine/article/193251/pediatrics/neonatal-hyperbilirubinemia-evidence-based-approach
MDedge Family Medicine; Emma J. Pace, MD, Carina M. Brown, MD et. al.

Jan 28th, 2019 - More than 60% of newborns appear clinically jaundiced in the first few weeks of life,1 most often due to physiologic jaundice. Mild hyperbilirubinemia peaks at Days 3 to 5 and returns to normal in the following weeks.

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