About 340 results

ALLMedicine™ Unconjugated Hyperbilirubinemia Center

Research & Reviews  126 results

Bilirubin Displacing Effect of Ceftriaxone in Term Infants with Unconjugated Hyperbilir...
The Journal of Pediatrics; Amin S

Nov 7th, 2022 - To evaluate the effect of intravenous (IV) ceftriaxone on free bilirubin concentrations in term infants with unconjugated hyperbilirubinemia. A prospective study was performed with subjects serving as their own controls. Our inclusion criteria wer...

Role of transcranial Doppler in assessment of cerebral blood flow in full term neonates...
Journal of Ultrasound; Kamel SM, Badr-Eldin RM et. al.

Aug 16th, 2022 - To evaluate the difference in cerebral blood flow in neonates with and without extreme unconjugated hyperbilirubinemia. Transcranial Doppler parameters of 26 full term newborns with extreme unconjugated hyperbilirubinemia (UCH) were compared to 13...

Chemoprevention of bilirubin encephalopathy with a nanoceutical agent.
Pediatric Research; Adhikari A, Bhutani VK et. al.

Jul 7th, 2022 - Targeted rapid degradation of bilirubin has the potential to thwart incipient bilirubin encephalopathy. We investigated a novel spinel-structured citrate-functionalized trimanganese tetroxide nanoparticle (C-Mn3O4 NP, the nanodrug) to degrade both...

Pernicious Anemia Differential Diagnoses

May 16th, 2022 - Diagnostic Considerations By definition, pernicious anemia refers specifically to vitamin B12 deficiency resulting from a lack of production of intrinsic factor (IF) in the stomach. However, vitamin B12 absorption is a complex process, and other c...

Light-Emitting Diode (LED) Phototherapy Versus Non-LED Phototherapy Devices for Hyperbi...
American Journal of Perinatology; Novoa RH, Huaman K et. al.

Apr 19th, 2022 - This review was conducted to evaluate the efficacy of light-emitting diode (LED) phototherapy as compared with the conventional phototherapy in neonates with unconjugated hyperbilirubinemia and their adverse effects. We searched the following data...

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Clinicaltrials.gov  7 results

Fenofibrate Therapy in Pathological Unconjugated Hyperbilirubinemia in Full Term Infants

Jun 5th, 2020 - Background: Despite widespread phototherapy usage, many newborn infants remain in need of other lines of invasive therapy such as intravenous immunoglobulins and exchange transfusions. Objective: To assess the efficacy and the safety of adding fen...

Registry of Congenital Dyserythropoietic Anemia

Jun 12th, 2019 - Congenital dyserythropoietic anemia is a heterogeneous inherited disease. Hyperplasic erythropoiesis is ineffective and associated with morphological abnormalities of some of the erythroblasts that form the basis of cytological classification. The...

Efficacy of Intravenous Immunoglobulin in Management of Rh and ABO Incompatibility Disease

Jun 27th, 2017 - Hemolytic disease of the newborn (HDN) due to red cell alloimmunisation is an important cause of hyperbilirubinemia with significant morbidity in the neonatal period . Hemolytic disease of the newborn has unfortunately continued to contribute to p...

Comparison Between Effect of Conventional, Intensive and Light Emitting Diodes (LED) Phototherapy on Oxidative Stress Among Neonates With Unconjugated Hyperbilirubinemia

Mar 8th, 2017 - The aim of the present study is to test a hypothesis assuming that phototherapy might have an effect on oxidant/antioxidant status in term and late-preterm neonates with unconjugated hyperbilirubinemia.

A Pilot Study of Moderate Hyperbilirubinemia in Type 1 Diabetes Mellitus

Jul 21st, 2014 - Diabetes mellitus (DM) is associated with a markedly increased risk of both macro- and microvascular disease. Excess pro-oxidants and insufficient antioxidants each contributes to oxidant stress in DM. Oxidant stress induces endothelial dysfunctio...

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News  3 results

FDA Asks Geron to Halt Imetelstat Development

Dec 4th, 2020 - John Chip Scarlett, MD The FDA has placed a full clinical hold on the development of the investigational telomerase inhibitor imetelstat following concerns over consistent low-grade liver function test (LFT) abnormalities, according to a verbal n...

Why Biliary Atresia Demands Our Respect

Aug 19th, 2020 - As I listened to our fellow present the case of a 5-month-old infant referred for evaluation of persistent jaundice, painful memories of several similar cases flashed by, causing me to ask, "Is this another late diagnosis of biliary atresia?" This...

Neonatal hyperbilirubinemia: An evidence-based approach
MDedge Family Medicine; Emma J. Pace, MD, Carina M. Brown, MD et. al.

Jan 28th, 2019 - More than 60% of newborns appear clinically jaundiced in the first few weeks of life,1 most often due to physiologic jaundice. Mild hyperbilirubinemia peaks at Days 3 to 5 and returns to normal in the following weeks.

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