×
About 655 results

ALLMedicine™ Membranoproliferative Glomerulonephritis Center

Research & Reviews  245 results

The yin and the yang of early classical pathway complement disorders.
https://doi.org/10.1093/cei/uxac056
Clinical and Experimental Immunology; Sullivan KE

Jun 2nd, 2022 - The classical pathway of the complement cascade has been recognized as a key activation arm, partnering with the lectin activation arm and the alternative pathway to cleave C3 and initiate the assembly of the terminal components. While deficiencie...

Use of a B-cell depleting regimen for antifactor H autoantibody-mediated membranoprolif...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021740
BMJ Case Reports; Henderson S, Ardill R et. al.

Apr 22nd, 2022 - A male child presented initially well with a mixed nephrotic-nephritic syndrome and was commenced on standard high-dose oral corticosteroids. Clinical deterioration occurred 3 weeks later with rapidly progressing renal dysfunction, seizures and di...

A novel FOXP3 mutation in a Chinese child with IPEX-associated membranous nephropathy.
https://doi.org/10.1002/mgg3.1945
Molecular Genetics & Genomic Medicine; Tan L, An Y et. al.

Apr 19th, 2022 - Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome is a monogenic immunodeficiency disease caused by forkhead box protein3 (FOXP3) mutation. The kidney is commonly involved in IPEX syndrome, but there were few studies ...

Recurrence of immune complex and complement-mediated membranoproliferative glomerulonep...
https://doi.org/10.1093/ndt/gfac148
Nephrology, Dialysis, Transplantation : Official Publicat... Caravaca-Fontán F, Polanco N et. al.

Apr 12th, 2022 - Membranoproliferative glomerulonephritis (MPGN) represents a histologic pattern of glomerular injury which may be due to several etiologies. Few studies have comprehensively analyzed the recurrence of MPGN according to the current classification s...

New Onset Biopsy-Proven Nephropathies after COVID Vaccination.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059008
American Journal of Nephrology; Fenoglio R, Lalloni S et. al.

Mar 31st, 2022 - To date, almost 7 billion doses of the different types of vaccine against SARS-CoV-2 have been administered worldwide. Although the severity of new cases of SARS-CoV-2 has progressively decreased, and the pressure on national health systems has de...

see more →

Clinicaltrials.gov  9 results

Phase III Study Assessing the Efficacy and Safety of Pegcetacoplan in Patients With C3 Glomerulopathy or Immune-Complex Membranoproliferative Glomerulonephritis
https://clinicaltrials.gov/ct2/show/NCT05067127

Mar 9th, 2022 - This is a Phase 3 study to assess the efficacy and safety of twice-weekly subcutaneous (SC) doses of pegcetacoplan compared to placebo in patients with C3 glomerulopathy (C3G) or immune-complex membranoproliferative glomerulonephritis (IC-MPGN) on...

Non-contrast Enhanced MRI in Patients With C3 Glomerulopathy (C3G) or Immune-complex Membranoproliferative Glomerulonephritis (IC-MPGN) Enrolled in the ACH471-205 Study
https://clinicaltrials.gov/ct2/show/NCT03723512

Nov 26th, 2021 - Functional and quantitative renal magnetic resonance imaging (MRI) has seen a number of recent advances, and techniques are now available that can generate quantitative imaging biomarkers with the potential to improve the management of kidney dise...

Prevalence of Renal Disease in Children With Celiac Disease
https://clinicaltrials.gov/ct2/show/NCT05049876

Oct 8th, 2021 - In this study the investigators seek to quantify the prevalence of urine sediment abnormalities in children with celiac disease to assess whether there is value in screening for renal disease in this population. Celiac disease (CD) is frequently a...

Eculizumab Therapy for Dense Deposit Disease and C3 Nephropathy
https://clinicaltrials.gov/ct2/show/NCT01221181

Feb 19th, 2019 - Dense deposit disease (DDD), also called membranoproliferative glomerulonephritis (MPGN) type II, is a rare form of glomerulonephritis named because of the characteristic appearance of electron-dense material in the glomerular basement membrane ob...

Chronic Hepatitis C in Chronic Hemodialysis Recipients - An Observational Study
https://clinicaltrials.gov/ct2/show/NCT03461250

Apr 3rd, 2018 - Epidemiological Data It is estimated that chronic infection with the chronic hepatitis C virus (HCV) affects approximately 180 million people worldwide (1). It has surpassed HIV infection as the leading cause of death from viral infection in multi...

see more →

News  8 results

A 58-Year-Old Man With a Rash and Elevated Creatinine Levels
https://reference.medscape.com/viewarticle/919074_4

Oct 2nd, 2019 - Clinicians should have a high index of suspicion for cryoglobulinemia in patients known to have HCV infection who present with nephritic syndrome, proteinuria, or renal dysfunction.[25] HBV and HIV are also associated with cryoglobulinemia; thus, ...

A Rare Case of Immunotactoid Glomerulopathy and Monoclonal Gammopathy of Renal Significance due to an IgM Kappa Clone at the VA Pittsburgh Healthcare System
https://www.mdedge.com/fedprac/avaho/article/207783/mixed-topics/rare-case-immunotactoid-glomerulopathy-and-monoclonal?channel=53
Kuang C, Alshoubaki N et. al.

Sep 9th, 2019 - Introduction: Monoclonal gammopathy of renal significance (MGRS) is a recently recognized disorder from pathologic M protein causing renal disease and minimal hematologic disease burden. Failure to treat leads to poor outcomes from progression to.

A Rare Case of Immunotactoid Glomerulopathy and Monoclonal Gammopathy of Renal Significance due to an IgM Kappa Clone at the VA Pittsburgh Healthcare System
https://www.mdedge.com/fedprac/avaho/article/207783/mixed-topics/rare-case-immunotactoid-glomerulopathy-and-monoclonal
Kuang C, Alshoubaki N et. al.

Sep 9th, 2019 - Introduction: Monoclonal gammopathy of renal significance (MGRS) is a recently recognized disorder from pathologic M protein causing renal disease and minimal hematologic disease burden. Failure to treat leads to poor outcomes from progression to.

A 65-Year-Old Man With Hypertension and Proteinuria
https://reference.medscape.com/viewarticle/852384_3

Oct 12th, 2015 - On the basis of the history, physical examination, and workup, what is the diagnosis? Your Peers Chose: Diabetic kidney disease 0% Hypertensive nephrosclerosis 0% Unrecovered AKI 0% Hepatitis C-related membranoproliferative glomerulonephritis 0% D...

HCV Treatment: What Can I Do Now? What's Coming Next?
https://www.medscape.com/viewarticle/849473_4

Aug 24th, 2015 - Options for Difficult-to-Treat Patients The HCV Guidance: Recommendations for Testing, Managing, and Treating Hepatitis C website[16] provides recommendations for the treatment of patients with decompensated HCV cirrhosis (Child-Turcotte-Pugh clas...

see more →