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About 336 results

ALLMedicine™ Essential Thrombocytosis Center

Research & Reviews  165 results

Genome editing to model and reverse a prevalent mutation associated with myeloprolifera...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932127
PloS One; Baik R, Wyman SK et. al.

Mar 4th, 2021 - Myeloproliferative neoplasms (MPNs) cause the over-production of blood cells such as erythrocytes (polycythemia vera) or platelets (essential thrombocytosis). JAK2 V617F is the most prevalent somatic mutation in many MPNs, but previous modeling of...

Applied genomics in MPN presentation.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727573
Hematology. American Society of Hematology. Education Pro... Moliterno AR, Kaizer H

Dec 4th, 2020 - Polycythemia vera, essential thrombocytosis (ET), and primary myelofibrosis (PMF) are grouped together as myeloproliferative neoplasms (MPNs) because of shared clinical, pathologic, and molecular features. The 2005 discovery of the driver mutation...

Hyperprogression on immunotherapy with complete response to chemotherapy in a NSCLC pat...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668523
Medicine Fricke J, Mambetsariev I et. al.

Nov 12th, 2020 - Patients reporting high PD-L1 expression have shown to respond well to immunotherapy; however, some patients develop hyperprogressive disease upon initiation of immune checkpoint inhibitors. We report a patient with lung cancer and 100% PD-L1 expr...

Determination of cerebral blood flow velocity and microembolic signals in essential thr...
https://doi.org/10.1080/01616412.2020.1833147
Neurological Research; Cinar A, Cetin G et. al.

Oct 14th, 2020 - The goal of treatment in essential thrombocytosis (ET) is to prevent vascular complications such as thrombosis and hemorrhage. This study aimed to evaluate the risk of cerebrovascular microembolism in ET patients due to detection of microembolic s...

Clonal hematopoietic mutations linked to platelet traits and the risk of thrombosis or ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395290
Haematologica Veninga A, De Simone I et. al.

Jun 19th, 2020 - Platelets are key elements in thrombosis, particularly in atherosclerosis-associated arterial thrombosis (atherothrombosis), and hemostasis. Megakaryocytes in the bone marrow, differentiated from hematopoietic stem cells are generally considered a...

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Clinicaltrials.gov  167 results

Genome editing to model and reverse a prevalent mutation associated with myeloprolifera...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932127
PloS One; Baik R, Wyman SK et. al.

Mar 4th, 2021 - Myeloproliferative neoplasms (MPNs) cause the over-production of blood cells such as erythrocytes (polycythemia vera) or platelets (essential thrombocytosis). JAK2 V617F is the most prevalent somatic mutation in many MPNs, but previous modeling of...

Applied genomics in MPN presentation.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727573
Hematology. American Society of Hematology. Education Pro... Moliterno AR, Kaizer H

Dec 4th, 2020 - Polycythemia vera, essential thrombocytosis (ET), and primary myelofibrosis (PMF) are grouped together as myeloproliferative neoplasms (MPNs) because of shared clinical, pathologic, and molecular features. The 2005 discovery of the driver mutation...

Hyperprogression on immunotherapy with complete response to chemotherapy in a NSCLC pat...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668523
Medicine Fricke J, Mambetsariev I et. al.

Nov 12th, 2020 - Patients reporting high PD-L1 expression have shown to respond well to immunotherapy; however, some patients develop hyperprogressive disease upon initiation of immune checkpoint inhibitors. We report a patient with lung cancer and 100% PD-L1 expr...

Determination of cerebral blood flow velocity and microembolic signals in essential thr...
https://doi.org/10.1080/01616412.2020.1833147
Neurological Research; Cinar A, Cetin G et. al.

Oct 14th, 2020 - The goal of treatment in essential thrombocytosis (ET) is to prevent vascular complications such as thrombosis and hemorrhage. This study aimed to evaluate the risk of cerebrovascular microembolism in ET patients due to detection of microembolic s...

Clonal hematopoietic mutations linked to platelet traits and the risk of thrombosis or ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395290
Haematologica Veninga A, De Simone I et. al.

Jun 19th, 2020 - Platelets are key elements in thrombosis, particularly in atherosclerosis-associated arterial thrombosis (atherothrombosis), and hemostasis. Megakaryocytes in the bone marrow, differentiated from hematopoietic stem cells are generally considered a...

see more →

News  4 results

Leukemia Cutis Presenting as Scrotal Ulcerations in a Patient With Acute Myelogenous Leukemia
https://www.mdedge.com/dermatology/article/100170/leukemia-cutis-presenting-scrotal-ulcerations-patient-acute-myelogenous/page/0/1

Jun 3rd, 2015 - The differential diagnosis of painful cutaneous ulcers in the setting of hematologic malignancy includes a variety of infectious and inflammatory etiologies such as ulcerative HSV, cytomegalovirus, Epstein-Barr virus, amoebic skin ulcerations, opp.

JAK2 Mutations and JAK Inhibitors in the Management of Myeloproliferative Neoplasms
https://www.onclive.com/publications/contemporary-oncology/2015/february-2015/jak2-mutations-and-jak-inhibitors-in-the-management-of-myeloproliferative-neoplasms

Jan 30th, 2015 - The Philadelphia chromosome–negative myeloproliferative neoplasms (MPNs) are clonal disorders characterized by common mutations, but with distinct clinical features, treatment considerations, and prognostic outlooks.1 Identification of the JAK2 (J...

Case Report: Headache in a Postpartum Patient With Essential Thrombocytosis
https://www.mdedge.com/emergencymedicine/article/82551/hematology/case-report-headache-postpartum-patient-essential/page/0/1

May 1st, 2014 - Conclusion This case describes a patient with two risk factors for CVT, a life-threatening condition. It should be considered in patients with ET and/or pregnant and postpartum patients presenting with headache or other neurological symptoms.

C. albicans appendicitis in a neutropenic patient after induction chemotherapy
https://www.mdedge.com/hematology-oncology/article/77462/leukemia-myelodysplasia-transplantation/c-albicans-appendicitis
Rohtesh S. Mehta, MD, MPH, MS, David Cohen, MD

Sep 4th, 2013 - A 62-year-old white man with a past medical history of hypertension and essential thrombocytosis diagnosed 17 years ago presented at our institution. He was being treated with hydroxyurea, with which he required occasional blood transfusions and p.

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