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About 320 results

ALLMedicine™ Essential Thrombocytosis Center

Research & Reviews  157 results

Clonal hematopoietic mutations linked to platelet traits and the risk of thrombosis or ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395290
Haematologica Veninga A, De Simone I et. al.

Jun 19th, 2020 - Platelets are key elements in thrombosis, particularly in atherosclerosis-associated arterial thrombosis (atherothrombosis), and hemostasis. Megakaryocytes in the bone marrow, differentiated from hematopoietic stem cells are generally considered a...

Sex determines the presentation and outcomes in MPN and is related to sex-specific diff...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322953
Blood Advances; Karantanos T, Chaturvedi S et. al.

Jun 16th, 2020 - The factors underlying the variable presentation and clinical course of myeloproliferative neoplasms (MPNs) remain unclear. The aim of this study was to evaluate the independent effect of sex on MPN presentation and outcomes. A total of 815 patien...

Prognostic models in the myeloproliferative neoplasms.
https://doi.org/10.1016/j.blre.2020.100713
Blood Reviews; Grinfeld J

Jun 13th, 2020 - The management of myelofibrosis (MF) is predominantly supportive, with the use of JAK2 inhibitors or allogeneic stem cell transplantation reserved for patients predicted to have poor overall survival. Identification of these patients is aided by a...

Thrombopoietin is required for full phenotype expression in a JAK2V617F transgenic mous...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263591
PloS One; Spivak JL, Merchant A et. al.

Jun 1st, 2020 - The myeloproliferative neoplasms, polycythemia vera, essential thrombocytosis and primary myelofibrosis are hematopoietic stem cell disorders and share driver mutations that either directly activate the thrombopoietin receptor, MPL, or activate it...

Atypical myeloproliferative neoplasm with concurrent BCR-ABL1 fusion and CALR mutation:...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004640
Medicine Liu C, Hu R et. al.

Jan 31st, 2020 - Concurrent calreticulin (CALR) mutation and BCR-ABL1 fusion are extremely rare in chronic myelogenous leukemia; to date, only 12 cases have been reported. A 57-year-old male who had an 11-year history of essential thrombocytosis presented to our h...

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Clinicaltrials.gov  159 results

Clonal hematopoietic mutations linked to platelet traits and the risk of thrombosis or ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395290
Haematologica Veninga A, De Simone I et. al.

Jun 19th, 2020 - Platelets are key elements in thrombosis, particularly in atherosclerosis-associated arterial thrombosis (atherothrombosis), and hemostasis. Megakaryocytes in the bone marrow, differentiated from hematopoietic stem cells are generally considered a...

Sex determines the presentation and outcomes in MPN and is related to sex-specific diff...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322953
Blood Advances; Karantanos T, Chaturvedi S et. al.

Jun 16th, 2020 - The factors underlying the variable presentation and clinical course of myeloproliferative neoplasms (MPNs) remain unclear. The aim of this study was to evaluate the independent effect of sex on MPN presentation and outcomes. A total of 815 patien...

Prognostic models in the myeloproliferative neoplasms.
https://doi.org/10.1016/j.blre.2020.100713
Blood Reviews; Grinfeld J

Jun 13th, 2020 - The management of myelofibrosis (MF) is predominantly supportive, with the use of JAK2 inhibitors or allogeneic stem cell transplantation reserved for patients predicted to have poor overall survival. Identification of these patients is aided by a...

Thrombopoietin is required for full phenotype expression in a JAK2V617F transgenic mous...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263591
PloS One; Spivak JL, Merchant A et. al.

Jun 1st, 2020 - The myeloproliferative neoplasms, polycythemia vera, essential thrombocytosis and primary myelofibrosis are hematopoietic stem cell disorders and share driver mutations that either directly activate the thrombopoietin receptor, MPL, or activate it...

Atypical myeloproliferative neoplasm with concurrent BCR-ABL1 fusion and CALR mutation:...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004640
Medicine Liu C, Hu R et. al.

Jan 31st, 2020 - Concurrent calreticulin (CALR) mutation and BCR-ABL1 fusion are extremely rare in chronic myelogenous leukemia; to date, only 12 cases have been reported. A 57-year-old male who had an 11-year history of essential thrombocytosis presented to our h...

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News  4 results

Leukemia Cutis Presenting as Scrotal Ulcerations in a Patient With Acute Myelogenous Leukemia
https://www.mdedge.com/dermatology/article/100170/leukemia-cutis-presenting-scrotal-ulcerations-patient-acute-myelogenous/page/0/1

Jun 3rd, 2015 - The differential diagnosis of painful cutaneous ulcers in the setting of hematologic malignancy includes a variety of infectious and inflammatory etiologies such as ulcerative HSV, cytomegalovirus, Epstein-Barr virus, amoebic skin ulcerations, opp.

JAK2 Mutations and JAK Inhibitors in the Management of Myeloproliferative Neoplasms
https://www.onclive.com/publications/contemporary-oncology/2015/february-2015/jak2-mutations-and-jak-inhibitors-in-the-management-of-myeloproliferative-neoplasms

Jan 30th, 2015 - The Philadelphia chromosome–negative myeloproliferative neoplasms (MPNs) are clonal disorders characterized by common mutations, but with distinct clinical features, treatment considerations, and prognostic outlooks.1 Identification of the JAK2 (J...

Case Report: Headache in a Postpartum Patient With Essential Thrombocytosis
https://www.mdedge.com/emergencymedicine/article/82551/hematology/case-report-headache-postpartum-patient-essential/page/0/1

May 1st, 2014 - Conclusion This case describes a patient with two risk factors for CVT, a life-threatening condition. It should be considered in patients with ET and/or pregnant and postpartum patients presenting with headache or other neurological symptoms.

C. albicans appendicitis in a neutropenic patient after induction chemotherapy
https://www.mdedge.com/hematology-oncology/article/77462/leukemia-myelodysplasia-transplantation/c-albicans-appendicitis
Rohtesh S. Mehta, MD, MPH, MS, David Cohen, MD

Sep 4th, 2013 - A 62-year-old white man with a past medical history of hypertension and essential thrombocytosis diagnosed 17 years ago presented at our institution. He was being treated with hydroxyurea, with which he required occasional blood transfusions and p.

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