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About 4,748 results

ALLMedicine™ Hemolytic Uremic Syndrome Center

Research & Reviews  2,287 results

Improved Renal Recovery with Eculizumab Therapy among Children with High Prevalence of ...
https://doi.org/10.1159/000510612
Kidney & Blood Pressure Research; Bamhraz AA, Rahim KA et. al.

Nov 25th, 2020 - Genetic defects that determine uncontrolled activation of the alternative complement pathway have been well documented, which account for approximately 40-60% of atypical hemolytic uremic syndrome (aHUS) cases worldwide. In Saudi Arabia, nearly ha...

Distinct genetic profile with recurrent population-specific missense variants in Korean...
https://doi.org/10.1016/j.thromres.2020.06.016
Thrombosis Research; Yun JW, Oh J et. al.

Nov 20th, 2020 - Atypical hemolytic uremic syndrome (aHUS) is a rare thrombotic microangiopathy (TMA), characterized by micro-angiopathic hemolytic anemia, thrombocytopenia, and renal failure. In more than half of cases, genetic defects leading to overactivation o...

Is the atypical hemolytic uremic syndrome risk polymorphism in Membrane Cofactor Protei...
https://doi.org/10.1111/petr.13903
Pediatric Transplantation REFERENCES; Sánchez-Moreno A, de la Cerda F et. al.

Nov 20th, 2020 - aHUS is a rare disease characterized by episodes of TMA that frequently progresses to CKD and often recurs after KT. The most frequent cause of aHUS is defective regulation of complement activation because of genetic anomalies. Eculizumab interrup...

Severely ill pediatric patients with Shiga toxin-associated hemolytic uremic syndrome (...
https://doi.org/10.1007/s00467-020-04829-4
Pediatric Nephrology (Berlin, Germany); Luna M, Kamariski M et. al.

Nov 18th, 2020 - Shiga toxin-producing Escherichia coli-associated hemolytic uremic syndrome (STEC-HUS) is the main cause of pediatric acute kidney injury (AKI) in Argentina. Endothelial injury is the trigger event in the microangiopathic process. The host inflamm...

Molecular characteristics of eae-positive clinical Shiga toxin-producing Escherichia co...
https://doi.org/10.1080/22221751.2020.1850182
Emerging Microbes & Infections; Hua Y, Bai X et. al.

Nov 12th, 2020 - Shiga toxin (Stx)-producing Escherichia coli (STEC) can cause a wide range of symptoms from asymptomatic carriage, mild diarrhea to bloody diarrhea (BD) and hemolytic uremic syndrome (HUS). Besides the Stx, intimin, encoded by the eae gene, also p...

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Guidelines  9 results

Outbreak of E. coli Infections
https://www.cdc.gov/ecoli/2019/o103-04-19/index.html

Apr 4th, 2019 - As of April 4, 2019, 72 people infected with the outbreak strain of E. coli O103 have been reported from five states. Eight people have been hospitalized. No cases of hemolytic uremic syndrome (HUS) or deaths have been reported.

Clinical guides for atypical hemolytic uremic syndrome in Japan.
https://doi.org/10.1007/s10157-016-1276-6
Clinical and Experimental Nephrology; Kato H, Nangaku M et. al.

Jul 16th, 2016 - Atypical hemolytic uremic syndrome (aHUS) is a rare disease characterized by the triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury. In 2013, we developed diagnostic criteria to enable early diagnosis and timely ...

An international consensus approach to the management of atypical hemolytic uremic synd...
https://doi.org/10.1007/s00467-015-3076-8
Pediatric Nephrology (Berlin, Germany); Loirat C, Fakhouri F et. al.

Apr 10th, 2015 - Atypical hemolytic uremic syndrome (aHUS) emerged during the last decade as a disease largely of complement dysregulation. This advance facilitated the development of novel, rational treatment options targeting terminal complement activation, e.g....

Guidelines for the management and investigation of hemolytic uremic syndrome.
https://doi.org/10.1007/s10157-014-0995-9
Clinical and Experimental Nephrology; Igarashi T, Ito S et. al.

Aug 7th, 2014 - Guidelines for the management and investigation of hemolytic uremic syndrome.|2014|Igarashi T,Ito S,Sako M,Saitoh A,Hataya H,|standards,diagnosis,etiology,therapy,standards,

Diagnostic criteria for atypical hemolytic uremic syndrome proposed by the Joint Commit...
https://doi.org/10.1007/s10157-013-0911-8
Clinical and Experimental Nephrology; Sawai T, Nangaku M et. al.

Dec 17th, 2013 - Atypical hemolytic uremic syndrome (aHUS) is rare and comprises the triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury. Recently, abnormalities in the mechanisms underlying complement regulation have been focused...

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Drugs  5 results see all →

Clinicaltrials.gov  2,349 results

Improved Renal Recovery with Eculizumab Therapy among Children with High Prevalence of ...
https://doi.org/10.1159/000510612
Kidney & Blood Pressure Research; Bamhraz AA, Rahim KA et. al.

Nov 25th, 2020 - Genetic defects that determine uncontrolled activation of the alternative complement pathway have been well documented, which account for approximately 40-60% of atypical hemolytic uremic syndrome (aHUS) cases worldwide. In Saudi Arabia, nearly ha...

Distinct genetic profile with recurrent population-specific missense variants in Korean...
https://doi.org/10.1016/j.thromres.2020.06.016
Thrombosis Research; Yun JW, Oh J et. al.

Nov 20th, 2020 - Atypical hemolytic uremic syndrome (aHUS) is a rare thrombotic microangiopathy (TMA), characterized by micro-angiopathic hemolytic anemia, thrombocytopenia, and renal failure. In more than half of cases, genetic defects leading to overactivation o...

Is the atypical hemolytic uremic syndrome risk polymorphism in Membrane Cofactor Protei...
https://doi.org/10.1111/petr.13903
Pediatric Transplantation REFERENCES; Sánchez-Moreno A, de la Cerda F et. al.

Nov 20th, 2020 - aHUS is a rare disease characterized by episodes of TMA that frequently progresses to CKD and often recurs after KT. The most frequent cause of aHUS is defective regulation of complement activation because of genetic anomalies. Eculizumab interrup...

Severely ill pediatric patients with Shiga toxin-associated hemolytic uremic syndrome (...
https://doi.org/10.1007/s00467-020-04829-4
Pediatric Nephrology (Berlin, Germany); Luna M, Kamariski M et. al.

Nov 18th, 2020 - Shiga toxin-producing Escherichia coli-associated hemolytic uremic syndrome (STEC-HUS) is the main cause of pediatric acute kidney injury (AKI) in Argentina. Endothelial injury is the trigger event in the microangiopathic process. The host inflamm...

Molecular characteristics of eae-positive clinical Shiga toxin-producing Escherichia co...
https://doi.org/10.1080/22221751.2020.1850182
Emerging Microbes & Infections; Hua Y, Bai X et. al.

Nov 12th, 2020 - Shiga toxin (Stx)-producing Escherichia coli (STEC) can cause a wide range of symptoms from asymptomatic carriage, mild diarrhea to bloody diarrhea (BD) and hemolytic uremic syndrome (HUS). Besides the Stx, intimin, encoded by the eae gene, also p...

see more →

News  91 results

FDA Clears Ravulizumab for Atypical Hemolytic Uremic Syndrome
https://www.medscape.com/viewarticle/920120

Oct 20th, 2019 - The US Food and Drug Administration (FDA) has approved ravulizumab (Ultomiris, Alexion Pharmaceuticals) to inhibit complement-mediated thrombotic microangiopathy (TMA) in adults and children age 1 month or older with atypical hemolytic uremic synd...

Hemolytic Uremic Syndrome With Severe Neurologic Complications in an Adult
https://www.mdedge.com/fedprac/article/202331/neurology/hemolytic-uremic-syndrome-severe-neurologic-complications-adult?channel=258
Ayan Nasir*, Nimai Patel* et. al.

Jun 5th, 2019 - Hemolytic uremic syndrome (HUS) is a rare illness that can be acquired through the consumption of food products contaminated with strains of Shiga toxin-producing Escherichia coli (E coli ; STEC). 1 Between 6% and 15% of individuals infected with.

June 2019 Management of Neurologic Disorders in Federal Health Care
https://www.mdedge.com/fedprac/article/203582/june-2019-management-neurologic-disorders-federal-health-care?channel=27011

Jun 1st, 2019 - Click here to access June 2019 Management of Neurologic Disorders in Federal Health Care Table of Contents Early and Accurate Identification of Parkinson Disease Among US Veterans Proton Pump Inhibitor Use and Risk of Dementia in the Veteran Popul.

Outbreak of E. coli Infections
https://www.cdc.gov/ecoli/2019/o103-04-19/index.html

Apr 4th, 2019 - As of April 4, 2019, 72 people infected with the outbreak strain of E. coli O103 have been reported from five states. Eight people have been hospitalized. No cases of hemolytic uremic syndrome (HUS) or deaths have been reported.

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Patient Education  7 results see all →