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About 4,945 results

ALLMedicine™ Hemolytic Uremic Syndrome Center

Research & Reviews  2,389 results

It takes two to thrombosis: Hemolysis and complement.
https://doi.org/10.1016/j.blre.2021.100834
Blood Reviews; Delvasto-Nuñez L, Jongerius I et. al.

May 14th, 2021 - Thromboembolic events represent the most common complication of hemolytic anemias characterized by complement-mediated hemolysis such as paroxysmal nocturnal hemoglobinuria and autoimmune hemolytic anemia. Similarly, atypical hemolytic uremic synd...

Tissue-resident macrophages mediate neutrophil recruitment and kidney injury in shiga t...
https://doi.org/10.1016/j.kint.2021.03.039
Kidney International; Lill JK, Thiebes S et. al.

Apr 30th, 2021 - Enterohaemorrhagic E. coli cause major epidemics worldwide with significant organ damage and very high percentages of death. Due to the ability of enterohaemorrhagic E. coli to produce shiga toxin these bacteria damage the kidney leading to the he...

Whole-Genome Sequencing of Shiga Toxin-Producing Escherichia coli OX18 from a Fatal Hem...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084502
Emerging Infectious Diseases; Lee K, Iguchi A et. al.

Apr 26th, 2021 - We report a fatal case of hemolytic uremic syndrome with urinary tract infection in Japan caused by Shiga toxin-producing Escherichia coli. We genotypically identified the isolate as OX18:H2. Whole-genome sequencing revealed 3 potentially pathogen...

Clinical and Genetic Characteristics of Atypical Hemolytic Uremic Syndrome in Children:...
https://doi.org/10.1159/000513009
Nephron Wu D, Chen J et. al.

Apr 19th, 2021 - Atypical hemolytic uremic syndrome (aHUS) is a rare but critical illness. To this date, few studies have reported on the disease in Chinese children. We studied a Chinese pediatric cohort to delineate the clinical characteristics, genotypes, and p...

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Guidelines  9 results

Outbreak of E. coli Infections
https://www.cdc.gov/ecoli/2019/o103-04-19/index.html

Apr 4th, 2019 - As of April 4, 2019, 72 people infected with the outbreak strain of E. coli O103 have been reported from five states. Eight people have been hospitalized. No cases of hemolytic uremic syndrome (HUS) or deaths have been reported.

Clinical guides for atypical hemolytic uremic syndrome in Japan.
https://doi.org/10.1007/s10157-016-1276-6
Clinical and Experimental Nephrology; Kato H, Nangaku M et. al.

Jul 16th, 2016 - Atypical hemolytic uremic syndrome (aHUS) is a rare disease characterized by the triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury. In 2013, we developed diagnostic criteria to enable early diagnosis and timely ...

An international consensus approach to the management of atypical hemolytic uremic synd...
https://doi.org/10.1007/s00467-015-3076-8
Pediatric Nephrology (Berlin, Germany); Loirat C, Fakhouri F et. al.

Apr 10th, 2015 - Atypical hemolytic uremic syndrome (aHUS) emerged during the last decade as a disease largely of complement dysregulation. This advance facilitated the development of novel, rational treatment options targeting terminal complement activation, e.g....

Guidelines for the management and investigation of hemolytic uremic syndrome.
https://doi.org/10.1007/s10157-014-0995-9
Clinical and Experimental Nephrology; Igarashi T, Ito S et. al.

Aug 7th, 2014 - Guidelines for the management and investigation of hemolytic uremic syndrome.|2014|Igarashi T,Ito S,Sako M,Saitoh A,Hataya H,|standards,diagnosis,etiology,therapy,standards,

Diagnostic criteria for atypical hemolytic uremic syndrome proposed by the Joint Commit...
https://doi.org/10.1007/s10157-013-0911-8
Clinical and Experimental Nephrology; Sawai T, Nangaku M et. al.

Dec 17th, 2013 - Atypical hemolytic uremic syndrome (aHUS) is rare and comprises the triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury. Recently, abnormalities in the mechanisms underlying complement regulation have been focused...

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Drugs  5 results see all →

Clinicaltrials.gov  2,447 results

It takes two to thrombosis: Hemolysis and complement.
https://doi.org/10.1016/j.blre.2021.100834
Blood Reviews; Delvasto-Nuñez L, Jongerius I et. al.

May 14th, 2021 - Thromboembolic events represent the most common complication of hemolytic anemias characterized by complement-mediated hemolysis such as paroxysmal nocturnal hemoglobinuria and autoimmune hemolytic anemia. Similarly, atypical hemolytic uremic synd...

Tissue-resident macrophages mediate neutrophil recruitment and kidney injury in shiga t...
https://doi.org/10.1016/j.kint.2021.03.039
Kidney International; Lill JK, Thiebes S et. al.

Apr 30th, 2021 - Enterohaemorrhagic E. coli cause major epidemics worldwide with significant organ damage and very high percentages of death. Due to the ability of enterohaemorrhagic E. coli to produce shiga toxin these bacteria damage the kidney leading to the he...

Whole-Genome Sequencing of Shiga Toxin-Producing Escherichia coli OX18 from a Fatal Hem...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084502
Emerging Infectious Diseases; Lee K, Iguchi A et. al.

Apr 26th, 2021 - We report a fatal case of hemolytic uremic syndrome with urinary tract infection in Japan caused by Shiga toxin-producing Escherichia coli. We genotypically identified the isolate as OX18:H2. Whole-genome sequencing revealed 3 potentially pathogen...

Clinical and Genetic Characteristics of Atypical Hemolytic Uremic Syndrome in Children:...
https://doi.org/10.1159/000513009
Nephron Wu D, Chen J et. al.

Apr 19th, 2021 - Atypical hemolytic uremic syndrome (aHUS) is a rare but critical illness. To this date, few studies have reported on the disease in Chinese children. We studied a Chinese pediatric cohort to delineate the clinical characteristics, genotypes, and p...

see more →

News  91 results

FDA Clears Ravulizumab for Atypical Hemolytic Uremic Syndrome
https://www.medscape.com/viewarticle/920120

Oct 20th, 2019 - The US Food and Drug Administration (FDA) has approved ravulizumab (Ultomiris, Alexion Pharmaceuticals) to inhibit complement-mediated thrombotic microangiopathy (TMA) in adults and children age 1 month or older with atypical hemolytic uremic synd...

Hemolytic Uremic Syndrome With Severe Neurologic Complications in an Adult
https://www.mdedge.com/fedprac/article/202331/neurology/hemolytic-uremic-syndrome-severe-neurologic-complications-adult?channel=258
Ayan Nasir*, Nimai Patel* et. al.

Jun 5th, 2019 - Hemolytic uremic syndrome (HUS) is a rare illness that can be acquired through the consumption of food products contaminated with strains of Shiga toxin-producing Escherichia coli (E coli ; STEC). 1 Between 6% and 15% of individuals infected with.

June 2019 Management of Neurologic Disorders in Federal Health Care
https://www.mdedge.com/fedprac/article/203582/june-2019-management-neurologic-disorders-federal-health-care?channel=27011

Jun 1st, 2019 - Click here to access June 2019 Management of Neurologic Disorders in Federal Health Care Table of Contents Early and Accurate Identification of Parkinson Disease Among US Veterans Proton Pump Inhibitor Use and Risk of Dementia in the Veteran Popul.

Outbreak of E. coli Infections
https://www.cdc.gov/ecoli/2019/o103-04-19/index.html

Apr 4th, 2019 - As of April 4, 2019, 72 people infected with the outbreak strain of E. coli O103 have been reported from five states. Eight people have been hospitalized. No cases of hemolytic uremic syndrome (HUS) or deaths have been reported.

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Patient Education  4 results see all →