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About 190 results

ALLMedicine™ Essential Thrombocytosis Center

Research & Reviews  73 results

Facial demodicosis in the immunosuppressed state: a retrospective case series from a te...
https://doi.org/10.1111/ijd.16162
International Journal of Dermatology; Amitay-Laish I, Solomon-Cohen E et. al.

Apr 11th, 2022 - Data on Demodex in the immunosuppressed state is limited, focusing mainly on patients with human immunodeficiency virus and hematological malignancies. The aim of this study was to describe the manifestations of facial demodicosis in diverse immun...

An inherited gain-of-function risk allele in EPOR predisposes to familial JAK2V617F mye...
https://doi.org/10.1111/bjh.18165
British Journal of Haematology; Rabadan Moraes G, Pasquier F et. al.

Apr 1st, 2022 - Myeloproliferative neoplasms (MPN) are mainly sporadic but inherited variants have been associated with higher risk development. Here, we identified an EPOR variant (EPORP488S ) in a large family diagnosed with JAK2V617F -positive polycythaemia ve...

Primary Myelofibrosis
https://emedicine.medscape.com/article/197954-overview

Mar 3rd, 2022 - Practice Essentials Primary myelofibrosis is a clonal disorder arising from the neoplastic transformation of early hematopoietic stem cells. [1, 2, 3, 4] Older terms for this disorder include agnogenic myeloid metaplasia with myelofibrosis and chr...

Primary Myelofibrosis
http://emedicine.medscape.com/article/197954-overview

Mar 3rd, 2022 - Practice Essentials Primary myelofibrosis is a clonal disorder arising from the neoplastic transformation of early hematopoietic stem cells. [1, 2, 3, 4] Older terms for this disorder include agnogenic myeloid metaplasia with myelofibrosis and chr...

JAK2 inhibitor persistence in MPN: uncovering a central role of ERK activation.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8792018
Blood Cancer Journal; Pandey G, Kuykendall AT et. al.

Jan 28th, 2022 - The Philadelphia chromosome negative myeloproliferative neoplasms, including polycythemia vera, essential thrombocytosis, and myelofibrosis, are driven by hyper activation of the JAK2 tyrosine kinase, the result of mutations in three MPN driving g...

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Clinicaltrials.gov  1 results

Open-Label Study of Oral CEP-701 (Lestaurtinib) in Patients With Polycythemia Vera or Essential Thrombocytosis
https://clinicaltrials.gov/ct2/show/NCT00586651

Oct 8th, 2015 - This is an 18-week open-label, multicenter study to evaluate the efficacy and tolerability of CEP-701 (lestaurtinib) treatment at a dosage of 80 mg bid for 18 weeks (126 days) in patients with Polycythemia Vera (PV) who have abnormal baseline neut...

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News  2 results

5 Questions... with Charles Morris, MD, VP of Worldwide Clinical Research, for Cephalon Oncology
https://www.onclive.com/view/ong_5qs_with_charles_morris

Mar 15th, 2022 - 1 Why are self-survival and self-renewing pathways such promising areas of discovery at this time for Cephalon? If we can understand the methods and the pathways by which cells are able to either prolong their survival or sustain their own prolif...

Case Report: Headache in a Postpartum Patient With Essential Thrombocytosis
https://www.mdedge.com/emergencymedicine/article/82551/hematology/case-report-headache-postpartum-patient-essential
Caleb P. Canders, MD, Taku Taira, MD

May 1st, 2014 - Case A 32-year-old woman, 4 weeks postpartum, presented to the ED with a chief complaint of headache, which she stated had become worse over the past 4 days. The headache was gradual-onset, bioccipital, and pressure-like.

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