ALLMedicine™ Transfusion Reactions Center

Jan 31st, 2023 - Children with a history of allergic transfusion reactions (ATRs) receive antihistamine premedication with or without hydrocortisone to prevent subsequent reactions. We aim to examine the frequency of developing ATRs to subsequent different blood p...

Jan 30th, 2023 - Hematopoietic stem cell transplantation using bone marrow as the graft source is a common treatment for hematopoietic malignancies and disorders. For allogeneic transplants, processing of bone marrow requires the depletion of ABO-mismatched red bl...

Jan 15th, 2023 - This study aimed to explore the ameliorating effects of the platelet surface glycoprotein (GP) IIb/IIIa receptor antagonist tirofiban on coagulation and fibrinolytic abnormalities in a mouse model of antibody-mediated transfusion-associated acute ...

Dec 30th, 2022 - Children have different clinical and physiological drivers for transfusion from adult recipients. However, adverse transfusion reactions (ATRs) in pediatric patients are usually reported using the same criteria as for adults. Broad assessments of ...

Dec 22nd, 2022 - Students who meet the criteria for inclusion in the study and agree to participate in the study will be divided into experimental and control groups using the computer-aided randomization system. After randomization, the appropriate time frame wil...

Jan 28th, 2020 - Red cell transfusions remain a mainstay of therapy for patients with sickle cell disease (SCD), but pose significant clinical challenges. Guidance for specific indications and administration of transfusion, as well as screening, prevention, and ma...

Apr 27th, 2018 - Red blood cell (RBC) transfusions remain essential in the treatment of patients with sickle cell disease (SCD) and β-thalassemia. Alloimmunization, a well-documented complication of transfusion, increases the risk of delayed hemolytic transfusion ...

Dec 22nd, 2022 - Students who meet the criteria for inclusion in the study and agree to participate in the study will be divided into experimental and control groups using the computer-aided randomization system. After randomization, the appropriate time frame wil...

Dec 6th, 2022 - This is a prospective, randomized, double-blind controlled trial to evaluate the efficacy of placebo versus chlorpheniramine for the prevention of allergic transfusion reactions.

Nov 23rd, 2022 - 125 nurses from the clinic and intensive care units, who received the most intensive blood transfusion from two different hospitals, were included in the study as the intervention and control groups. The control group was not trained. Only the pre...

Oct 13th, 2022 - Anemic patients from Mulago Hospital Complex who require fresh whole blood transfusion and with any of the following conditions will be considered for recruitment: cancer, general medical or surgical, obstetric hemorrhage, and/or sickle cell. Elig...

Aug 12th, 2022 - High-dose chemotherapy followed by autologous stem cell transplant is considered standard of care for patients with relapsed and/or refractory aggressive lymphomas. High-dose chemotherapy, with or without ASCT, may also be used as upfront chemothe...

Apr 6th, 2022 - MANCHESTER — Over a fifth of reported blood transfusion reactions are in patients with sickle cell disease, over half of which involve the potentially life-threatening complication hyperhaemolysis, suggests a UK analysis. "Haemolytic transfusion r...

Dec 23rd, 2021 - Improvements in blood storage that extend the life of red blood cells (RBCs) will ultimately allow patients with hematologic malignancies to receive fewer transfusions less often, according to Steven L. Spitalnik, MD. This is the aim of a new stor...

Sep 1st, 2021 - Jared Weiss, MD: Considering how well the myelosuppressive treatments work, such as G-CSF [granulocyte colony-stimulating factor] and ESAs [erythropoietin-stimulating agents], there’s a lot to be desired. Beginning with neutropenia, pegfilgrastim ...

Apr 2nd, 2021 - Transcript:David P. Steensma, MD: We assess patients with myelodysplastic syndromes in several ways. The fundamental thing that we want to know when we first meet a new patient, about their MDS, is, are they a patient who has higher-risk disease w...

Apr 2nd, 2021 - Transcript:Thomas Prebet, MD, PhD: The question of transfusions in myelodysplastic syndromes, especially red blood cell transfusion, is a very crucial one. Firstly, because it’s the type of treatment that is most commonly used worldwide for patien...