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About 1,545 results

ALLMedicine™ Transfusion Reactions Center

Research & Reviews  409 results

Cost-effectiveness of pathogen reduction technology for plasma and platelets in Québec:...
https://doi.org/10.1111/trf.16926
Transfusion Grégoire Y, Delage G et. al.

May 14th, 2022 - The last economic evaluation of pathogen reduction technology (PRT) in Canada was conducted in 2007. We reassessed the cost-effectiveness of PRT in the province of Québec (which has its own blood supplier) and included an evaluation of the potenti...

Exploring the rationale for red cell transfusion in myelodysplastic syndrome patients: ...
https://doi.org/10.1080/17474086.2022.2077721
Expert Review of Hematology; Finelli C, Parisi S et. al.

May 14th, 2022 - Anemia is often present in mostly elderly patients with myelodysplastic syndromes (MDS), and is associated with a poorer outcome. Although red blood cell (RBC) transfusions are the most immediate treatment, waiting for the response to disease-spec...

Randomised controlled trial of glucose-6-phosphate dehydrogenase deficient versus non-d...
https://doi.org/10.1111/tme.12871
Transfusion Medicine (Oxford, England); Krajibthong S, Sahntipurna V et. al.

May 10th, 2022 - Recent studies revealed the glucose-6-phosphate dehydrogenase (G-6-PD) deficiency prevalence of 7.7-10% among Thai blood donors. Transfusion of red blood cells (RBCs) from these subjects potentially causes haemolysis in recipients. RBC units from ...

Midodrine Versus Albumin for Prevention of Paracentesis Induced Circulatory Disturbance
https://clinicaltrials.gov/ct2/show/NCT05240391

May 10th, 2022 - Paracentesis-induced circulatory disturbance (PICD) is a very common cause of mortality and morbidity in patients undergoing large-volume paracentesis. Albumin is commonly used in decompensated cirrhosis during large-volume paracentesis. However, ...

Hypersensitivity transfusion reactions to fresh frozen plasma: a retrospective analysis...
https://doi.org/10.1016/j.tmrv.2022.04.002
Transfusion Medicine Reviews; Tacquard C, Andreu G et. al.

May 3rd, 2022 - Few data are currently available on hypersensitivity transfusion reactions (HTRs) after exposure to fresh frozen plasma (FFP). Between 2000 and 2018, three different FFP production strategies have been used in France, leading to the concomitant us...

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Guidelines  2 results

American Society of Hematology 2020 guidelines for sickle cell disease: transfusion sup...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988392
Blood Advances; Chou ST, Alsawas M et. al.

Jan 28th, 2020 - Red cell transfusions remain a mainstay of therapy for patients with sickle cell disease (SCD), but pose significant clinical challenges. Guidance for specific indications and administration of transfusion, as well as screening, prevention, and ma...

Red blood cell specifications for patients with hemoglobinopathies: a systematic review...
https://doi.org/10.1111/trf.14611
Transfusion Compernolle V, Chou ST et. al.

Apr 27th, 2018 - Red blood cell (RBC) transfusions remain essential in the treatment of patients with sickle cell disease (SCD) and β-thalassemia. Alloimmunization, a well-documented complication of transfusion, increases the risk of delayed hemolytic transfusion ...

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Drugs  167 results see all →

Clinicaltrials.gov  15 results

Midodrine Versus Albumin for Prevention of Paracentesis Induced Circulatory Disturbance
https://clinicaltrials.gov/ct2/show/NCT05240391

May 10th, 2022 - Paracentesis-induced circulatory disturbance (PICD) is a very common cause of mortality and morbidity in patients undergoing large-volume paracentesis. Albumin is commonly used in decompensated cirrhosis during large-volume paracentesis. However, ...

Tranexamic Acid to Reduce Blood Loss in Spine Trauma Surgery
https://clinicaltrials.gov/ct2/show/NCT02314988

Mar 8th, 2022 - Reducing perioperative blood loss is critically important in the treatment of multiply injured combat casualties, and major blood loss during complex spine trauma surgery is a significant concern. Similar to previous studies in dental, cardiac, an...

Erythropoietin to Prevent Unnecessary Transfusions In Patients With Cyanotic CHD - A Prospective Control Trial
https://clinicaltrials.gov/ct2/show/NCT02564796

Dec 2nd, 2021 - Congenital heart disease occurs in about 1% of all live births. Cyanotic cardiac lesions in particular are at risk for significant mortality and morbidity because of their reduced ability to provide adequate oxygenation to the body and the brain. ...

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Escalating Multiple Oral Doses of AG-348 in Subjects With Stable Sickle Cell Disease
https://clinicaltrials.gov/ct2/show/NCT04000165

Sep 10th, 2021 - Sickle cell disease (SCD) is a multisystem disorder associated with episodes of acute clinical events and progressive organ damage. Episodic pain, triggered by micro-vasoocclusion induced by sickled red blood cells, is the most common acute compli...

Mechanisms of Anaphylaxis
https://clinicaltrials.gov/ct2/show/NCT03182491

Jun 16th, 2021 - The purpose of this study is to explore different mechanisms for anaphylaxis and find novel biomarkers for this hypersensitivity syndrome. The study participants are patients with anaphylaxis, patients with mild allergic reactions, and patients wi...

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News  24 results

Greater Care Needed Over Transfusions in Sickle Cell Disease
https://www.medscape.com/viewarticle/971657

Apr 6th, 2022 - MANCHESTER — Over a fifth of reported blood transfusion reactions are in patients with sickle cell disease, over half of which involve the potentially life-threatening complication hyperhaemolysis, suggests a UK analysis. "Haemolytic transfusion r...

Induction and Post-Induction Therapy for Adult ALL
https://www.onclive.com/view/induction-and-post-induction-therapy-for-adult-all

Apr 2nd, 2021 - Transcript:Bijal D. Shah, MD: Risk stratification in acute lymphoblastic leukemia (ALL) is absolutely the next most important thing we can do to improve outcomes. Now, risk stratification involves, I think, fundamentally two components. The first ...

Management of Cancer-Related Anemia in 2011
https://www.onclive.com/view/management-of-cancer-related-anemia-in-2011

Dec 5th, 2020 - Eric H. Kraut, MD Erythropoietin-stimulating agents (ESAs), once considered miracle drugs that enjoyed widespread use for cancer-related anemia, fell into disfavor in 2007, when evidence demonstrated that ESAs decreased survival and time to dise...

FDA OKs Emergency Use of Convalescent Plasma for Seriously Ill COVID-19 Patients
https://www.staging.medscape.com/viewarticle/927716

Mar 28th, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's  Coronavirus Resource Center. As the proportion of patients infected with COVID-19 continues to rise in the United States, the Food and Drug Administration is facilitating acc...

FDA OKs Emergency Use of Convalescent Plasma for Seriously Ill COVID-19 Patients
https://www.medscape.com/viewarticle/927716

Mar 28th, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's  Coronavirus Resource Center. As the proportion of patients infected with COVID-19 continues to rise in the United States, the Food and Drug Administration is facilitating acc...

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Patient Education  1 results see all →