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About 1,955 results

ALLMedicine™ Transfusion Reactions Center

Research & Reviews  512 results

Do Children With an Allergic Transfusion Reaction Require Premedication or All Blood Pr...
https://doi.org/10.1097/MPH.0000000000002630
Journal of Pediatric Hematology/oncology; Bahabri A, Barty R et. al.

Jan 31st, 2023 - Children with a history of allergic transfusion reactions (ATRs) receive antihistamine premedication with or without hydrocortisone to prevent subsequent reactions. We aim to examine the frequency of developing ATRs to subsequent different blood p...

Optimizing a fully automated and closed system process for red blood cell reduction of ...
https://doi.org/10.1016/j.jcyt.2022.12.006
Cytotherapy Remley VA, Collins A et. al.

Jan 30th, 2023 - Hematopoietic stem cell transplantation using bone marrow as the graft source is a common treatment for hematopoietic malignancies and disorders. For allogeneic transplants, processing of bone marrow requires the depletion of ABO-mismatched red bl...

PLATELET SUPPRESSION BY TIROFIBAN AMELIORATES PULMONARY COAGULATION AND FIBRINOLYSIS AB...
https://doi.org/10.1097/SHK.0000000000002080
Shock (Augusta, Ga.); Yuan X, Jiang P et. al.

Jan 15th, 2023 - This study aimed to explore the ameliorating effects of the platelet surface glycoprotein (GP) IIb/IIIa receptor antagonist tirofiban on coagulation and fibrinolytic abnormalities in a mouse model of antibody-mediated transfusion-associated acute ...

Dissecting the complexity of pediatric blood transfusions and risk of adverse reactions...
https://doi.org/10.2450/2022.0178-22
Blood Transfusion = Trasfusione Del Sangue; Wei WH, Cho G et. al.

Dec 30th, 2022 - Children have different clinical and physiological drivers for transfusion from adult recipients. However, adverse transfusion reactions (ATRs) in pediatric patients are usually reported using the same criteria as for adults. Broad assessments of ...

The Effect of Game-Based Activity on Blood Transfusion in Nursing Students
https://clinicaltrials.gov/ct2/show/NCT05661526

Dec 22nd, 2022 - Students who meet the criteria for inclusion in the study and agree to participate in the study will be divided into experimental and control groups using the computer-aided randomization system. After randomization, the appropriate time frame wil...

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Guidelines  2 results

American Society of Hematology 2020 guidelines for sickle cell disease: transfusion sup...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988392
Blood Advances; Chou ST, Alsawas M et. al.

Jan 28th, 2020 - Red cell transfusions remain a mainstay of therapy for patients with sickle cell disease (SCD), but pose significant clinical challenges. Guidance for specific indications and administration of transfusion, as well as screening, prevention, and ma...

Red blood cell specifications for patients with hemoglobinopathies: a systematic review...
https://doi.org/10.1111/trf.14611
Transfusion Compernolle V, Chou ST et. al.

Apr 27th, 2018 - Red blood cell (RBC) transfusions remain essential in the treatment of patients with sickle cell disease (SCD) and β-thalassemia. Alloimmunization, a well-documented complication of transfusion, increases the risk of delayed hemolytic transfusion ...

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Drugs  181 results see all →

Clinicaltrials.gov  44 results

The Effect of Game-Based Activity on Blood Transfusion in Nursing Students
https://clinicaltrials.gov/ct2/show/NCT05661526

Dec 22nd, 2022 - Students who meet the criteria for inclusion in the study and agree to participate in the study will be divided into experimental and control groups using the computer-aided randomization system. After randomization, the appropriate time frame wil...

Efficacy of Placebo Versus Chlorpheniramine for the Prevention of Allergic Transfusion Reactions.
https://clinicaltrials.gov/ct2/show/NCT04688736

Dec 6th, 2022 - This is a prospective, randomized, double-blind controlled trial to evaluate the efficacy of placebo versus chlorpheniramine for the prevention of allergic transfusion reactions.

EFFICIENCY OF HEMOVIGILANCE MODULE TRAININGS GIVEN TO NURSES
https://clinicaltrials.gov/ct2/show/NCT05625672

Nov 23rd, 2022 - 125 nurses from the clinic and intensive care units, who received the most intensive blood transfusion from two different hospitals, were included in the study as the intervention and control groups. The control group was not trained. Only the pre...

Mirasol Evaluation of Reduction in Infections Trial
https://clinicaltrials.gov/ct2/show/NCT03737669

Oct 13th, 2022 - Anemic patients from Mulago Hospital Complex who require fresh whole blood transfusion and with any of the following conditions will be considered for recruitment: cancer, general medical or surgical, obstetric hemorrhage, and/or sickle cell. Elig...

Secondary Prophylaxis in Non-Hodgkin Lymphoma (NHL) and Chemotherapy-induced Thrombocytopenia
https://clinicaltrials.gov/ct2/show/NCT01516619

Aug 12th, 2022 - High-dose chemotherapy followed by autologous stem cell transplant is considered standard of care for patients with relapsed and/or refractory aggressive lymphomas. High-dose chemotherapy, with or without ASCT, may also be used as upfront chemothe...

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News  42 results

Greater Care Needed Over Transfusions in Sickle Cell Disease
https://www.medscape.com/viewarticle/971657

Apr 6th, 2022 - MANCHESTER — Over a fifth of reported blood transfusion reactions are in patients with sickle cell disease, over half of which involve the potentially life-threatening complication hyperhaemolysis, suggests a UK analysis. "Haemolytic transfusion r...

Hypoxic Storage Could Extend Red Blood Cell Life, Thereby Reduce Transfusion Frequency in Hematologic Malignancies
https://www.onclive.com/view/hypoxic-storage-could-extend-red-blood-cell-life-thereby-reduce-transfusion-frequency-in-hematologic-malignancies

Dec 23rd, 2021 - Improvements in blood storage that extend the life of red blood cells (RBCs) will ultimately allow patients with hematologic malignancies to receive fewer transfusions less often, according to Steven L. Spitalnik, MD. This is the aim of a new stor...

Limitations When Managing Chemo-Induced Myelosuppression
https://www.onclive.com/view/limitations-when-managing-chemo-induced-myelosuppression

Sep 1st, 2021 - Jared Weiss, MD: Considering how well the myelosuppressive treatments work, such as G-CSF [granulocyte colony-stimulating factor] and ESAs [erythropoietin-stimulating agents], there’s a lot to be desired. Beginning with neutropenia, pegfilgrastim ...

How Iron Accumulation Occurs in MDS
https://www.onclive.com/view/how-iron-accumulation-occurs-in-mds

Apr 2nd, 2021 - Transcript:David P. Steensma, MD: We assess patients with myelodysplastic syndromes in several ways. The fundamental thing that we want to know when we first meet a new patient, about their MDS, is, are they a patient who has higher-risk disease w...

The Effects of Blood Transfusions on Iron Accumulation
https://www.onclive.com/view/the-effects-of-blood-transfusions-on-iron-accumulation

Apr 2nd, 2021 - Transcript:Thomas Prebet, MD, PhD: The question of transfusions in myelodysplastic syndromes, especially red blood cell transfusion, is a very crucial one. Firstly, because it’s the type of treatment that is most commonly used worldwide for patien...

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Patient Education  1 results see all →