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About 105 results

ALLMedicine™ X-linked Lymphoproliferative Syndrome Center

Research & Reviews  40 results

Potential pathogenic mechanism of type 1 X-linked lymphoproliferative syndrome caused b...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575725
Medicine Wang Y, Wang Y et. al.

Oct 19th, 2022 - X-linked lymphoproliferative syndrome (XLP) is a rare X-linked recessive inborn errors of immunity. The pathogenesis of XLP might be related to phophatidylinositol-3-kinase (PI3K)-associated pathways but insight details remain unclear. This study ...

Preemptive hematopoietic cell transplantation for asymptomatic patients with X-linked l...
https://doi.org/10.1016/j.clim.2022.108993
Clinical Immunology (Orlando, Fla.); Tomomasa D, Booth C et. al.

Apr 4th, 2022 - Few reports have examined whether prophylactic allogeneic hematopoietic cell transplantation (HCT) for X-linked lymphoproliferative syndrome type 1 (XLP1) improves the prognosis. We compared the prognosis of symptomatic probands and affected sibli...

Exon skipping caused by a complex structural variation in SH2D1A resulted in X-linked l...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922962
Molecular Genetics & Genomic Medicine; Wu L, Yang F et. al.

Jan 30th, 2022 - X-linked lymphoproliferative syndrome type 1 (XLP1) is a rare primary immunodeficiency disorder characterized by severe immune dysregulation often after viral infection. It is caused by hemizygous mutations in the X-linked SH2D1A gene. People with...

X-linked Lymphoproliferative Syndrome
https://emedicine.medscape.com/article/203780-overview

Jan 24th, 2022 - Practice Essentials X-linked lymphoproliferative (XLP) syndrome is a rare recessive genetic disorder that can be divided into two types based on its genetic cause and pattern of signs and symptoms. X-linked lymphoproliferative syndrome type 1 (XLP...

X-linked Lymphoproliferative Syndrome
http://emedicine.medscape.com/article/203780-overview

Jan 24th, 2022 - Practice Essentials X-linked lymphoproliferative (XLP) syndrome is a rare recessive genetic disorder that can be divided into two types based on its genetic cause and pattern of signs and symptoms. X-linked lymphoproliferative syndrome type 1 (XLP...

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Clinicaltrials.gov  1 results

Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies
https://clinicaltrials.gov/ct2/show/NCT00006054

Oct 15th, 2009 - PROTOCOL OUTLINE: Patients with severe combined immunodeficiency (SCID) using a matched sibling donor receive allogeneic bone marrow or umbilical cord blood transplantation on day 0. Patients receive graft versus host disease (GVHD) prophylaxis wi...

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News  1 results

Long-term endocrine effects common after reduced-intensity chemotherapy in children
https://www.mdedge.com/endocrinology/article/98295/pediatrics/long-term-endocrine-effects-common-after-reduced-intensity
M. Alexander Otto

Mar 26th, 2015 - SAN DIEGO – Remain vigilant for endocrine side effects after reduced-intensity conditioning for hematopoietic stem cell transplants in children. Traditionally, hematopoietic stem cell transplants (HSCT) for leukemia and other malignancies are prec.

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