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About 25,927 results

ALLMedicine™ Adenovirus Center

Research & Reviews  12,793 results

E3 ubiquitin ligase Mindbomb 1 facilitates nuclear delivery of adenovirus genomes.
https://doi.org/10.1073/pnas.2015794118
Proceedings of the National Academy of Sciences of the United States of America; Sarbanes SL, Blomen VA et. al.

Jan 14th, 2021 - The journey from plasma membrane to nuclear pore is a critical step in the lifecycle of DNA viruses, many of which must successfully deposit their genomes into the nucleus for replication. Viral capsids navigate this vast distance through the coor...

The immunological impact of adenovirus early genes on vaccine-induced responses in mice...
https://doi.org/10.1128/JVI.02253-20
Journal of Virology; Sangare K, Tuero I et. al.

Jan 14th, 2021 - Adenovirus (Ad) is being explored for use in the prevention and treatment of a variety of infectious diseases and cancers. Ad with a deletion in early region 3 (ΔE3) provokes a stronger immune response than Ad with deletions in early regions 1 and...

Coxsackievirus B3 Infection Early in Pregnancy Induces Congenital Heart Defects Through...
https://doi.org/10.1161/JAHA.120.017995
Journal of the American Heart Association; Sharma V, Goessling LS et. al.

Jan 14th, 2021 - Background Coxsackievirus B (CVB) is the most common cause of viral myocarditis. It targets cardiomyocytes through coxsackie and adenovirus receptor, which is highly expressed in the fetal heart. We hypothesized CVB3 can precipitate congenital hea...

Possible nosocomial transmission of virus-associated hemorrhagic cystitis after allogen...
https://doi.org/10.1007/s00277-021-04414-1
Annals of Hematology; Onda Y, Kanda J et. al.

Jan 13th, 2021 - Adenovirus (ADV)- or BK virus (BKV)-associated hemorrhagic cystitis (HC) is a common complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Several risk factors have been previously reported; however, it is unclear whet...

Interim Results of a Phase 1-2a Trial of Ad26.COV2.S Covid-19 Vaccine.
https://doi.org/10.1056/NEJMoa2034201
The New England Journal of Medicine; Sadoff J, Le Gars M et. al.

Jan 13th, 2021 - Efficacious vaccines are urgently needed to contain the ongoing coronavirus disease 2019 (Covid-19) pandemic of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A candidate vaccine, Ad26.COV2.S, is a recombinant, replic...

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Guidelines  4 results

Disinfection of Tonometers
https://www.aaojournal.org/article/S0161-6420(17)31677-9/fulltext
Anna K. Junk

Nov 30th, 2017 - Sodium hypochlorite (dilute bleach) offers effective disinfection against adenovirus and HSV, the viruses commonly associated with nosocomial outbreaks in eye care. Tonometer prisms should be examined regularly for signs of damage.

Community acquired respiratory virus infections in cancer patients-Guideline on diagnos...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125955
European Journal of Cancer (Oxford, England : 1990); von Lilienfeld-Toal M, Berger A et. al.

Sep 29th, 2016 - Community acquired viruses (CRVs) may cause severe disease in cancer patients. Thus, efforts should be made to diagnose CRV rapidly and manage CRV infections accordingly. A panel of 18 clinicians from the Infectious Diseases Working Party of the G...

Coronaviruses and Immunosuppressed Patients: The Facts During the Third Epidemic
https://aasldpubs.onlinelibrary.wiley.com/doi/full/10.1002/lt.25756

Following the outbreak in China, the Lombardy region of Italy has become one of the areas of highest incidence of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). As the outbreak grew to a pandemic, many centers worldwide raised the c...

The Oxford/AstraZeneca COVID-19 Vaccine: Encouraging Interim Results
https://www.jwatch.org/na52864/2020/12/15/oxford-astrazeneca-covid-19-vaccine-encouraging-interim
NEJM Journal Watch; del Rio C, .

This adenovirus-vectored vaccine appears effective against symptomatic COVID-19, with similar immunogenicity across age groups and lower reactogenicity in older individuals. The ChAdOx1 nCoV-19 vaccine (also known as AZD1222), developed by Oxfo...

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Drugs  19 results see all →

Clinicaltrials.gov  12,941 results

E3 ubiquitin ligase Mindbomb 1 facilitates nuclear delivery of adenovirus genomes.
https://doi.org/10.1073/pnas.2015794118
Proceedings of the National Academy of Sciences of the United States of America; Sarbanes SL, Blomen VA et. al.

Jan 14th, 2021 - The journey from plasma membrane to nuclear pore is a critical step in the lifecycle of DNA viruses, many of which must successfully deposit their genomes into the nucleus for replication. Viral capsids navigate this vast distance through the coor...

The immunological impact of adenovirus early genes on vaccine-induced responses in mice...
https://doi.org/10.1128/JVI.02253-20
Journal of Virology; Sangare K, Tuero I et. al.

Jan 14th, 2021 - Adenovirus (Ad) is being explored for use in the prevention and treatment of a variety of infectious diseases and cancers. Ad with a deletion in early region 3 (ΔE3) provokes a stronger immune response than Ad with deletions in early regions 1 and...

Coxsackievirus B3 Infection Early in Pregnancy Induces Congenital Heart Defects Through...
https://doi.org/10.1161/JAHA.120.017995
Journal of the American Heart Association; Sharma V, Goessling LS et. al.

Jan 14th, 2021 - Background Coxsackievirus B (CVB) is the most common cause of viral myocarditis. It targets cardiomyocytes through coxsackie and adenovirus receptor, which is highly expressed in the fetal heart. We hypothesized CVB3 can precipitate congenital hea...

Possible nosocomial transmission of virus-associated hemorrhagic cystitis after allogen...
https://doi.org/10.1007/s00277-021-04414-1
Annals of Hematology; Onda Y, Kanda J et. al.

Jan 13th, 2021 - Adenovirus (ADV)- or BK virus (BKV)-associated hemorrhagic cystitis (HC) is a common complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Several risk factors have been previously reported; however, it is unclear whet...

Interim Results of a Phase 1-2a Trial of Ad26.COV2.S Covid-19 Vaccine.
https://doi.org/10.1056/NEJMoa2034201
The New England Journal of Medicine; Sadoff J, Le Gars M et. al.

Jan 13th, 2021 - Efficacious vaccines are urgently needed to contain the ongoing coronavirus disease 2019 (Covid-19) pandemic of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A candidate vaccine, Ad26.COV2.S, is a recombinant, replic...

see more →

News  169 results

Two-Vaccine Regimen Yields Best Antibody Response to Ebola
https://www.medscape.com/viewarticle/939303

Oct 18th, 2020 - NEW YORK (Reuters Health) - Sequential administration of two different Ebola vaccines spaced several weeks apart yields the best antibody responses, according to an early trial. Dr. Neil Goldstein of Janssen Infectious Diseases and Vaccines, in Le...

CanSino coronavirus vaccine appears safe in first human trial
https://www.reuters.com/article/us-health-coronavirus-vaccine-cansino/cansino-coronavirus-vaccine-appears-safe-in-first-human-trial-idUSKBN22Y2EM

May 22nd, 2020 - (Reuters) - A coronavirus vaccine tested for the first time in humans is safe and induces a rapid immune response, researchers at China’s CanSino Biologics Inc reported on Friday in The Lancet medical journal. Blood samples from a group of 108 vac...

Oxford COVID-19 Vaccine Trial 'Within Weeks': Q&A
https://www.staging.medscape.com/viewarticle/928941

Apr 17th, 2020 - Editor's note, 22nd April 2020: human trials of the Oxford project's COVID-19 vaccine are due to begin tomorrow. UK experts have been giving updates on progress towards a COVID-19 vaccine in an online event hosted by the Science Media Centre. The ...

COVID-19 Characteristics Differ in Children vs Adults
https://www.medscape.com/viewarticle/926805

Mar 12th, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Pediatric cases of COVID-19 infection are typically mild, but underlying coinfection may be more common in children than in adults, according to a...

Gene therapy appears effective in bladder cancer patients with few options
https://www.mdedge.com/fedprac/avaho/article/217925/genitourinary-cancer/gene-therapy-appears-effective-bladder-cancer?channel=263
Susan London

Feb 26th, 2020 - SAN FRANCISCO – A novel gene therapy may expand treatment options for non–muscle invasive bladder cancer that does not respond to Bacillus Calmette-Guerin (BCG), new research suggests. Susan London/MDedge News Dr.

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Patient Education  1 results see all →