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About 848 results

ALLMedicine™ Arenaviruses Center

Research & Reviews  423 results

Inhibition of Arenaviruses by Combinations of Orally Available Approved Drugs.
https://doi.org/10.1128/AAC.01146-20
Antimicrobial Agents and Chemotherapy; Herring S, Oda JM et. al.

Jan 20th, 2021 - Neglected diseases caused by arenaviruses such as Lassa (LASV) and filoviruses like Ebola (EBOV) primarily afflict resource-limited countries, where antiviral drug development is often minimal. Previous studies have shown that many approved drugs ...

High-Throughput Screening of an FDA-Approved Drug Library Identifies Inhibitors against...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671101
ACS Infectious Diseases; Wan W, Zhu S et. al.

Nov 13th, 2020 - Arenaviruses are a large family of enveloped negative-strand RNA viruses that include several causative agents of severe hemorrhagic fevers. Currently, there are no FDA-licensed drugs to treat arenavirus infection except for the off-labeled use of...

Multiple DNA viruses identified in multimammate mouse (Mastomys natalensis) populations...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497350
Archives of Virology; Calvignac-Spencer S, Kouadio L et. al.

Aug 5th, 2020 - The multimammate mouse (Mastomys natalensis; M. natalensis) serves as the main reservoir for the zoonotic arenavirus Lassa virus (LASV), and this has led to considerable investigation into the distribution of LASV and other related arenaviruses in...

CACNA1S haploinsufficiency confers resistance to New World arenavirus infection.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431027
Proceedings of the National Academy of Sciences of the Un... Sarute N, Ross SR

Jul 28th, 2020 - Understanding the genetics of susceptibility to infectious agents is of great importance to our ability to combat disease. Here, we show that voltage-gated calcium channels (VGCCs) are critical for cellular binding and entry of the New World arena...

Complete genome sequence of Tacaribe virus.
https://doi.org/10.1007/s00705-020-04681-9
Archives of Virology; Holzerland J, Leske A et. al.

May 26th, 2020 - Tacaribe virus (TCRV) is the prototype of the New World arenaviruses (also known as TCRV serocomplex viruses). While TCRV is not itself a human pathogen, many closely related members of this group cause hemorrhagic fever, and thus TCRV has long se...

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Clinicaltrials.gov  425 results

Inhibition of Arenaviruses by Combinations of Orally Available Approved Drugs.
https://doi.org/10.1128/AAC.01146-20
Antimicrobial Agents and Chemotherapy; Herring S, Oda JM et. al.

Jan 20th, 2021 - Neglected diseases caused by arenaviruses such as Lassa (LASV) and filoviruses like Ebola (EBOV) primarily afflict resource-limited countries, where antiviral drug development is often minimal. Previous studies have shown that many approved drugs ...

High-Throughput Screening of an FDA-Approved Drug Library Identifies Inhibitors against...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671101
ACS Infectious Diseases; Wan W, Zhu S et. al.

Nov 13th, 2020 - Arenaviruses are a large family of enveloped negative-strand RNA viruses that include several causative agents of severe hemorrhagic fevers. Currently, there are no FDA-licensed drugs to treat arenavirus infection except for the off-labeled use of...

Multiple DNA viruses identified in multimammate mouse (Mastomys natalensis) populations...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497350
Archives of Virology; Calvignac-Spencer S, Kouadio L et. al.

Aug 5th, 2020 - The multimammate mouse (Mastomys natalensis; M. natalensis) serves as the main reservoir for the zoonotic arenavirus Lassa virus (LASV), and this has led to considerable investigation into the distribution of LASV and other related arenaviruses in...

CACNA1S haploinsufficiency confers resistance to New World arenavirus infection.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431027
Proceedings of the National Academy of Sciences of the Un... Sarute N, Ross SR

Jul 28th, 2020 - Understanding the genetics of susceptibility to infectious agents is of great importance to our ability to combat disease. Here, we show that voltage-gated calcium channels (VGCCs) are critical for cellular binding and entry of the New World arena...

Complete genome sequence of Tacaribe virus.
https://doi.org/10.1007/s00705-020-04681-9
Archives of Virology; Holzerland J, Leske A et. al.

May 26th, 2020 - Tacaribe virus (TCRV) is the prototype of the New World arenaviruses (also known as TCRV serocomplex viruses). While TCRV is not itself a human pathogen, many closely related members of this group cause hemorrhagic fever, and thus TCRV has long se...

see more →