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About 15,109 results

ALLMedicine™ Epstein-barr Virus Center

Research & Reviews  7,457 results

Targeting the PD-1/ PD-L1 interaction in nasopharyngeal carcinoma.
https://doi.org/10.1016/j.oraloncology.2020.105127
Oral Oncology; Johnson D, Ma BBY

Jan 17th, 2021 - Upregulation of the programmed cell death receptor-1 and ligand (PD-1/PD-L1) pathway is one of many possible mechanisms of immune-evasion relevant to Epstein-Barr virus (EBV)- associated nasopharyngeal cancer (NPC). The therapeutic targeting of th...

Characterizing EBV-associated lymphoproliferative diseases and the role of myeloid-deri...
https://doi.org/10.1182/blood.2020005611
Blood Collins PJ, Fox CP et. al.

Jan 14th, 2021 - Chronic active Epstein-Barr virus (CAEBV) typically presents as persistent infectious mononucleosis-like disease and/or hemophagocytic lymphohistocytosis (HLH), reflecting ectopic Epstein-Barr virus (EBV) infection and lymphoproliferation of T and...

Super-enhancers for RUNX3 are required for cell proliferation in EBV-infected B cell li...
https://doi.org/10.1016/j.gene.2021.145421
Gene Hosoi H, Nambu A et. al.

Jan 14th, 2021 - Epstein-Barr virus nuclear antigens 2 (EBNA2) mediated super-enhancers, defined by in silico data, localize near genes associated with B cell transcription factors including RUNX3. However, the biological function of super-enhancer for RUNX3 gene ...

RNA m6 A methylation regulates virus-host interaction and EBNA2 expression during Epste...
https://doi.org/10.1002/iid3.396
Immunity, Inflammation and Disease REFERENCES; Zheng X, Wang J et. al.

Jan 12th, 2021 - N6 -methyladenosine (m6 A) is the most prevalent modification that occurs in messenger RNA (mRNA), affecting mRNA splicing, translation, and stability. This modification is reversible, and its related biological functions are mediated by "writers,...

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Guidelines  1 results

Risk Factors Associated with the Onset of Relapsing-Remitting and Primary Progressive Multiple Sclerosis: A Systematic Review
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329850/
BioMed Research International;

Jan 30th, 2015 - Multiple sclerosis (MS) is a chronic central nervous system disease with a highly heterogeneous course. The aetiology of MS is not well understood but is likely a combination of both genetic and environmental factors. Approximately 85% of patients...

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Drugs  21 results see all →

Clinicaltrials.gov  7,547 results

Targeting the PD-1/ PD-L1 interaction in nasopharyngeal carcinoma.
https://doi.org/10.1016/j.oraloncology.2020.105127
Oral Oncology; Johnson D, Ma BBY

Jan 17th, 2021 - Upregulation of the programmed cell death receptor-1 and ligand (PD-1/PD-L1) pathway is one of many possible mechanisms of immune-evasion relevant to Epstein-Barr virus (EBV)- associated nasopharyngeal cancer (NPC). The therapeutic targeting of th...

Characterizing EBV-associated lymphoproliferative diseases and the role of myeloid-deri...
https://doi.org/10.1182/blood.2020005611
Blood Collins PJ, Fox CP et. al.

Jan 14th, 2021 - Chronic active Epstein-Barr virus (CAEBV) typically presents as persistent infectious mononucleosis-like disease and/or hemophagocytic lymphohistocytosis (HLH), reflecting ectopic Epstein-Barr virus (EBV) infection and lymphoproliferation of T and...

Super-enhancers for RUNX3 are required for cell proliferation in EBV-infected B cell li...
https://doi.org/10.1016/j.gene.2021.145421
Gene Hosoi H, Nambu A et. al.

Jan 14th, 2021 - Epstein-Barr virus nuclear antigens 2 (EBNA2) mediated super-enhancers, defined by in silico data, localize near genes associated with B cell transcription factors including RUNX3. However, the biological function of super-enhancer for RUNX3 gene ...

RNA m6 A methylation regulates virus-host interaction and EBNA2 expression during Epste...
https://doi.org/10.1002/iid3.396
Immunity, Inflammation and Disease REFERENCES; Zheng X, Wang J et. al.

Jan 12th, 2021 - N6 -methyladenosine (m6 A) is the most prevalent modification that occurs in messenger RNA (mRNA), affecting mRNA splicing, translation, and stability. This modification is reversible, and its related biological functions are mediated by "writers,...

see more →

News  81 results

Schizophrenia patients have ‘aberrant’ response to Epstein-Barr
https://www.mdedge.com/psychiatry/article/210181/schizophrenia-other-psychotic-disorders/schizophrenia-patients-have?channel=293
Christopher Palmer

Oct 15th, 2019 - Individuals with schizophrenia had elevated levels of one Epstein-Barr virus (EBV) antibody but atypically low levels of another, which investigators deemed an “aberrant immune response. ” Faith Dickerson, PhD, MPH, Lorraine Jones-Brando, PhD,and c.

Vitamin D Boosts, Smoking Clouds Cognition in MS
https://www.medscape.com/viewarticle/903457

Oct 14th, 2018 - BERLIN — Higher vitamin D levels at the time of a diagnosis of a clinically isolated syndrome (CIS) were associated with better cognitive performance 11 years later. In contrast, cigarette smoking was linked to worse long-term cognition. Seroposit...

Epstein-Barr ‘Switches On” Autoimmune Genes
https://www.mdedge.com/fedprac/article/168262/mixed-topics/epstein-barr-switches-autoimmune-genes

Jun 16th, 2018 - The Epstein-Barr virus (EBV) protein can “switch on” risk genes for autoimmune diseases, according to researchers from the National Institute of Allergy and Infectious Diseases. They found that when EBV infects human immune cells, the virus produc.

Mortality in patients with PTLD
https://www.mdedge.com/hematology-oncology/article/185058/transplantation/mortality-patients-ptld
HT Staff

Mar 25th, 2018 - Benjamin Chaigne-Delalande Cell infected with Epstein-Barr virus (green/red) among uninfected cells (blue) Image courtesy of LISBON—A review of recent studies has revealed a “significant burden” of mortality related to post-transplant lymphoprolif.

Mono May Boost MS Risk
https://www.medpagetoday.com/neurology/multiplesclerosis/67624

Aug 30th, 2017 - Action Points Patients who have had mononucleosis due to infection with Epstein-Barr virus (EBV) may be at increased risk of multiple sclerosis (MS). Note that the data support the hygiene hypothesis: that being born/spending your early childhood ...

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Patient Education  2 results see all →