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About 261 results

ALLMedicine™ Norwalk Virus Center

Research & Reviews  127 results

Less severe clinical symptoms of Norwalk virus 8fIIb inoculum compared to its precursor...
https://doi.org/10.1002/jmv.26578
Journal of Medical Virology; Liu P, Rahman M et. al.

Oct 5th, 2020 - Noroviruses (NoV) are a leading cause of epidemic gastroenteritis. Human challenge studies have been used to examine the infectivity, pathogenicity, and host immune response to NoV as well as vaccine efficacy. The goal of this study was to conduct...

Production and Clinical Evaluation of Norwalk GI.1 Virus Lot 001-09NV in Norovirus Vacc...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050988
The Journal of Infectious Diseases; Mateo R, Lindesmith LC et. al.

Oct 19th, 2019 - Human noroviruses (HuNoV) are the leading cause of gastroenteritis. No vaccine is currently available to prevent norovirus illness or infection. Safe, infectious challenge strains are needed to assess vaccine efficacy in the controlled human infec...

Bile Salts Alter the Mouse Norovirus Capsid Conformation: Possible Implications for Cel...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744230
Journal of Virology; Sherman MB, Williams AN et. al.

Jul 25th, 2019 - Caliciviruses are single-stranded RNA viruses with 180 copies of capsid protein comprising the T=3 icosahedral capsids. The main capsid feature is a pronounced protruding (P) domain dimer formed by adjacent subunits on the icosahedral surface whil...

Selection and Characterization of Rupintrivir-Resistant Norwalk Virus Replicon Cells In...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923142
Antimicrobial Agents and Chemotherapy; Kitano M, Hosmillo M et. al.

Mar 13th, 2018 - Human norovirus (HuNoV) is a major cause of nonbacterial gastroenteritis worldwide, yet despite its impact on society, vaccines and antivirals are currently lacking. A HuNoV replicon system has been widely applied to the evaluation of antiviral co...

Norwalk Vaccine Study
https://clinicaltrials.gov/ct2/show/NCT00973284

Aug 7th, 2017 - The drug being tested in this study is called intranasal Norwalk virus-like particle (VLP) vaccine. Norwalk VLP vaccine is being tested to prevent viral acute gastroenteritis (AGE). This study will look at the illness rate of AGE in people who are...

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Clinicaltrials.gov  131 results

Less severe clinical symptoms of Norwalk virus 8fIIb inoculum compared to its precursor...
https://doi.org/10.1002/jmv.26578
Journal of Medical Virology; Liu P, Rahman M et. al.

Oct 5th, 2020 - Noroviruses (NoV) are a leading cause of epidemic gastroenteritis. Human challenge studies have been used to examine the infectivity, pathogenicity, and host immune response to NoV as well as vaccine efficacy. The goal of this study was to conduct...

Production and Clinical Evaluation of Norwalk GI.1 Virus Lot 001-09NV in Norovirus Vacc...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050988
The Journal of Infectious Diseases; Mateo R, Lindesmith LC et. al.

Oct 19th, 2019 - Human noroviruses (HuNoV) are the leading cause of gastroenteritis. No vaccine is currently available to prevent norovirus illness or infection. Safe, infectious challenge strains are needed to assess vaccine efficacy in the controlled human infec...

Bile Salts Alter the Mouse Norovirus Capsid Conformation: Possible Implications for Cel...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744230
Journal of Virology; Sherman MB, Williams AN et. al.

Jul 25th, 2019 - Caliciviruses are single-stranded RNA viruses with 180 copies of capsid protein comprising the T=3 icosahedral capsids. The main capsid feature is a pronounced protruding (P) domain dimer formed by adjacent subunits on the icosahedral surface whil...

Selection and Characterization of Rupintrivir-Resistant Norwalk Virus Replicon Cells In...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923142
Antimicrobial Agents and Chemotherapy; Kitano M, Hosmillo M et. al.

Mar 13th, 2018 - Human norovirus (HuNoV) is a major cause of nonbacterial gastroenteritis worldwide, yet despite its impact on society, vaccines and antivirals are currently lacking. A HuNoV replicon system has been widely applied to the evaluation of antiviral co...

Norwalk Vaccine Study
https://clinicaltrials.gov/ct2/show/NCT00973284

Aug 7th, 2017 - The drug being tested in this study is called intranasal Norwalk virus-like particle (VLP) vaccine. Norwalk VLP vaccine is being tested to prevent viral acute gastroenteritis (AGE). This study will look at the illness rate of AGE in people who are...

see more →

News  3 results

Investigational Norovirus Vaccine Trims Norwalk Infection Risk
https://www.mdedge.com/familymedicine/article/46639/infectious-diseases/investigational-norovirus-vaccine-trims-norwalk
Internal Medicine News; Mary Ann Moon

Dec 7th, 2011 - An investigational norovirus vaccine was protective against Norwalk virus infection and its associated gastroenteritis in a proof-of-concept study reported in the Dec. 8 issue of the New England Journal of Medicine.

Norwalk Virus Vaccine Promises Smoother Sailing
https://www.medpagetoday.com/infectiousdisease/vaccines/30082

Dec 7th, 2011 - Action Points Explain that it might be possible to use a vaccine to prevent norovirus illness. Point out that the duration of protection from vaccination is unclear, and the vaccine evaluated in the study protected against the Norwalk strain (geno...

MDCT of the Small Bowel
https://www.medscape.com/viewarticle/769704_6

Infection Infectious enteritis is a common cause of acute diarrheal illness in the United States and can be caused by viruses, bacteria, or, less commonly, protozoa. The most common viral causes include norovirus (formerly Norwalk virus) and rotav...

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