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About 254 results

ALLMedicine™ Norwalk Virus Center

Research & Reviews  125 results

Production and Clinical Evaluation of Norwalk GI.1 Virus Lot 001-09NV in Norovirus Vacc...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050988
The Journal of Infectious Diseases; Mateo R, Lindesmith LC et. al.

Oct 19th, 2019 - Human noroviruses (HuNoV) are the leading cause of gastroenteritis. No vaccine is currently available to prevent norovirus illness or infection. Safe, infectious challenge strains are needed to assess vaccine efficacy in the controlled human infec...

Bile Salts Alter the Mouse Norovirus Capsid Conformation: Possible Implications for Cel...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744230
Journal of Virology; Sherman MB, Williams AN et. al.

Jul 25th, 2019 - Caliciviruses are single-stranded RNA viruses with 180 copies of capsid protein comprising the T=3 icosahedral capsids. The main capsid feature is a pronounced protruding (P) domain dimer formed by adjacent subunits on the icosahedral surface whil...

Selection and Characterization of Rupintrivir-Resistant Norwalk Virus Replicon Cells In...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923142
Antimicrobial Agents and Chemotherapy; Kitano M, Hosmillo M et. al.

Mar 13th, 2018 - Human norovirus (HuNoV) is a major cause of nonbacterial gastroenteritis worldwide, yet despite its impact on society, vaccines and antivirals are currently lacking. A HuNoV replicon system has been widely applied to the evaluation of antiviral co...

Norwalk Vaccine Study
https://clinicaltrials.gov/ct2/show/NCT00973284

Aug 7th, 2017 - The drug being tested in this study is called intranasal Norwalk virus-like particle (VLP) vaccine. Norwalk VLP vaccine is being tested to prevent viral acute gastroenteritis (AGE). This study will look at the illness rate of AGE in people who are...

The Norovirus NS3 Protein Is a Dynamic Lipid- and Microtubule-Associated Protein Involv...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244318
Journal of Virology; Cotton BT, Hyde JL et. al.

Nov 24th, 2016 - Norovirus (NoV) infections are a significant health burden to society, yet the lack of reliable tissue culture systems has hampered the development of appropriate antiviral therapies. Here we show that the NoV NS3 protein, derived from murine NoV ...

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Clinicaltrials.gov  127 results

Production and Clinical Evaluation of Norwalk GI.1 Virus Lot 001-09NV in Norovirus Vacc...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050988
The Journal of Infectious Diseases; Mateo R, Lindesmith LC et. al.

Oct 19th, 2019 - Human noroviruses (HuNoV) are the leading cause of gastroenteritis. No vaccine is currently available to prevent norovirus illness or infection. Safe, infectious challenge strains are needed to assess vaccine efficacy in the controlled human infec...

Bile Salts Alter the Mouse Norovirus Capsid Conformation: Possible Implications for Cel...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744230
Journal of Virology; Sherman MB, Williams AN et. al.

Jul 25th, 2019 - Caliciviruses are single-stranded RNA viruses with 180 copies of capsid protein comprising the T=3 icosahedral capsids. The main capsid feature is a pronounced protruding (P) domain dimer formed by adjacent subunits on the icosahedral surface whil...

Selection and Characterization of Rupintrivir-Resistant Norwalk Virus Replicon Cells In...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923142
Antimicrobial Agents and Chemotherapy; Kitano M, Hosmillo M et. al.

Mar 13th, 2018 - Human norovirus (HuNoV) is a major cause of nonbacterial gastroenteritis worldwide, yet despite its impact on society, vaccines and antivirals are currently lacking. A HuNoV replicon system has been widely applied to the evaluation of antiviral co...

Norwalk Vaccine Study
https://clinicaltrials.gov/ct2/show/NCT00973284

Aug 7th, 2017 - The drug being tested in this study is called intranasal Norwalk virus-like particle (VLP) vaccine. Norwalk VLP vaccine is being tested to prevent viral acute gastroenteritis (AGE). This study will look at the illness rate of AGE in people who are...

The Norovirus NS3 Protein Is a Dynamic Lipid- and Microtubule-Associated Protein Involv...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244318
Journal of Virology; Cotton BT, Hyde JL et. al.

Nov 24th, 2016 - Norovirus (NoV) infections are a significant health burden to society, yet the lack of reliable tissue culture systems has hampered the development of appropriate antiviral therapies. Here we show that the NoV NS3 protein, derived from murine NoV ...

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News  2 results

Investigational Norovirus Vaccine Trims Norwalk Infection Risk
https://www.mdedge.com/familymedicine/article/46639/infectious-diseases/investigational-norovirus-vaccine-trims-norwalk
Internal Medicine News; Mary Ann Moon

Dec 7th, 2011 - An investigational norovirus vaccine was protective against Norwalk virus infection and its associated gastroenteritis in a proof-of-concept study reported in the Dec. 8 issue of the New England Journal of Medicine.

Norwalk Virus Vaccine Promises Smoother Sailing
https://www.medpagetoday.com/infectiousdisease/vaccines/30082

Dec 7th, 2011 - Action Points Explain that it might be possible to use a vaccine to prevent norovirus illness. Point out that the duration of protection from vaccination is unclear, and the vaccine evaluated in the study protected against the Norwalk strain (geno...

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