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About 16,138 results

ALLMedicine™ Adenovirus Center

Research & Reviews  5,729 results

Combining intramuscular and intranasal homologous prime-boost with a chimpanzee adenovi...
https://doi.org/10.1080/22221751.2022.2097479
Emerging Microbes & Infections; Li X, Wang L et. al.

Jul 2nd, 2022 - The efficacy of many coronavirus disease 2019 (COVID-19) vaccines has been shown to decrease to varying extents against new severe acute respiratory syndrome coronavirus 2 variants, which are responsible for the continuing COVID-19 pandemic. Combi...

The Natural History of Severe Viral Infections and Characterization of Immune Defects in Patients Without Known Immunocompromise
https://clinicaltrials.gov/ct2/show/NCT01011712

Jul 1st, 2022 - Viral infections in the normal host are usually self-limited as the innate and acquired immune systems mount successful antiviral responses. However, in some instances, apparently immunocompetent persons manifest infections with viruses that would...

Safety and Immunogenicity of Ad4-HIV Envelope Vaccine Vectors in Healthy Volunteers
https://clinicaltrials.gov/ct2/show/NCT03878121

Jul 1st, 2022 - This is a Phase 1 study to evaluate the immunogenicity and safety of adenovirus serotype 4 (Ad4)-based HIV vaccines when administered via the intranasal route to healthy human volunteers. It is hypothesized that the vaccines will be safe for human...

Follow-Up Evaluation for Gene-Therapy-Related Delayed Adverse Events After Participation in Pediatric Oncology Branch Clinical Trials
https://clinicaltrials.gov/ct2/show/NCT02315599

Jul 1st, 2022 - Background: Study subjects exposed to gene therapy interventions may be at risk for delayed or longterm adverse consequences. The U.S. Food and Drug Administration (FDA) has issued Long Term Follow-up After Administration of Human Gene Therapy Pro...

VB-111 in Combination With Nivolumab in People With Metastatic Colorectal Cancer (mCRC)
https://clinicaltrials.gov/ct2/show/NCT04166383

Jul 1st, 2022 - Background: Immune based approaches in GI cancers have unfortunately- with the notable exception of immune checkpoint inhibition in microsatellite instable (MSI-H) disease and gastric cancer-been largely unsuccessful. The reasons for this are uncl...

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Guidelines  1 results

Community acquired respiratory virus infections in cancer patients-Guideline on diagnos...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125955
European Journal of Cancer (Oxford, England : 1990); von Lilienfeld-Toal M, Berger A et. al.

Sep 30th, 2016 - Community acquired viruses (CRVs) may cause severe disease in cancer patients. Thus, efforts should be made to diagnose CRV rapidly and manage CRV infections accordingly. A panel of 18 clinicians from the Infectious Diseases Working Party of the G...

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Drugs  13 results see all →

Clinicaltrials.gov  402 results

The Natural History of Severe Viral Infections and Characterization of Immune Defects in Patients Without Known Immunocompromise
https://clinicaltrials.gov/ct2/show/NCT01011712

Jul 1st, 2022 - Viral infections in the normal host are usually self-limited as the innate and acquired immune systems mount successful antiviral responses. However, in some instances, apparently immunocompetent persons manifest infections with viruses that would...

Safety and Immunogenicity of Ad4-HIV Envelope Vaccine Vectors in Healthy Volunteers
https://clinicaltrials.gov/ct2/show/NCT03878121

Jul 1st, 2022 - This is a Phase 1 study to evaluate the immunogenicity and safety of adenovirus serotype 4 (Ad4)-based HIV vaccines when administered via the intranasal route to healthy human volunteers. It is hypothesized that the vaccines will be safe for human...

Follow-Up Evaluation for Gene-Therapy-Related Delayed Adverse Events After Participation in Pediatric Oncology Branch Clinical Trials
https://clinicaltrials.gov/ct2/show/NCT02315599

Jul 1st, 2022 - Background: Study subjects exposed to gene therapy interventions may be at risk for delayed or longterm adverse consequences. The U.S. Food and Drug Administration (FDA) has issued Long Term Follow-up After Administration of Human Gene Therapy Pro...

VB-111 in Combination With Nivolumab in People With Metastatic Colorectal Cancer (mCRC)
https://clinicaltrials.gov/ct2/show/NCT04166383

Jul 1st, 2022 - Background: Immune based approaches in GI cancers have unfortunately- with the notable exception of immune checkpoint inhibition in microsatellite instable (MSI-H) disease and gastric cancer-been largely unsuccessful. The reasons for this are uncl...

Comparing Safety and Protective Efficacy of Vaccine Candidate PfSPZ-CVac and MVA ME-TRAP/ ChAd63 ME-TRAP in Adults
https://clinicaltrials.gov/ct2/show/NCT05441410

Jul 1st, 2022 - This is a single centre, randomized, placebo-controlled phase 1/2 study comparing two malaria vaccine candidates. The first vaccine candidate PfSPZ-CVac (Plasmodium falciparum sporozoites (PfSPZ) challenge administered with a chemoprophylactic ant...

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News  308 results

Cidofovir for Pediatric Adenovirus-Related Hepatitis Rapidly Reduces Viremia
https://www.medscape.com/viewarticle/976459

Jul 1st, 2022 - NEW YORK (Reuters Health) - Off-label use of cidofovir in children with acute liver failure and confirmed adenovirus infection cleared the virus or substantially reduced viremia in a small case series from Kings College Hospital, London. Dr. Avita...

Acute Hepatitis Cases in Children Show Declining Trend; Adenovirus, COVID-19 Remain Key Leads
https://www.medscape.com/viewarticle/976174

Jun 24th, 2022 - LONDON ― Case numbers of acute hepatitis in children show "a declining trajectory," and COVID-19 and adenovirus remain the most likely, but as yet unproven, causative agents, said experts in an update at the International Liver Congress (ILC) 2022...

CDC Releases New Details on Mysterious Hepatitis in Children
https://www.medscape.com/viewarticle/976200

Jun 24th, 2022 - A new analysis from the Centers for Disease Control and Prevention (CDC) provides further details on mysterious cases of pediatric hepatitis identified across the United States. While 45% percent of patients have tested positive for adenovirus inf...

Past COVID-19 Infection Could Play Role in Child Hepatitis
https://www.medscape.com/viewarticle/975789

Jun 16th, 2022 - June 16, 2022 – There may be a link between the recent unexplained cases of hepatitis in children and prior coronavirus infections, according to new research from Israel. A new study details five children in Israel who had mild cases of COVID-19 w...

Pediatric Hepatitis Has Not Increased During Pandemic: CDC
https://www.medscape.com/viewarticle/975627

Jun 15th, 2022 - The number of pediatric hepatitis cases has remained steady since 2017, new research from the Centers for Disease Control and Prevention (CDC) suggests, despite the recent investigation into children with hepatitis of unknown cause. The study also...

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Patient Education  2 results see all →