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About 17,125 results

ALLMedicine™ Adenovirus Center

Research & Reviews  5,995 results

HNRNPA2B1-mediated m6A modification of TLR4 mRNA promotes progression of multiple myeloma.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673362
Journal of Translational Medicine; Quan L, Jia C et. al.

Nov 20th, 2022 - Multiple myeloma (MM) is a malignancy of plasma cells that remains incurable. Toll-like receptor 4 (TLR4) acts as a stress-responsive signal, protecting mitochondria during proteasome inhibitor (PI) exposure, maintaining mitochondrial metabolism a...

Viremia as a predictor of absence of serious bacterial infection in children with fever...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672567
European Journal of Pediatrics; Galetto-Lacour A, Cordey S et. al.

Nov 19th, 2022 - Most children with fever without source (FWS) require diagnostic laboratory tests to exclude a serious bacterial infection (SBI), often followed by admission and empirical antibiotics. As febrile children with a viral infection are less likely to ...

Respiratory microorganisms in acute pharyngitis patients: Identification, antibiotic pr...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671416
PloS One; Bo ZM, Tan WK et. al.

Nov 18th, 2022 - Acute pharyngitis (AP) is a common reason for private primary care consultations, thus providing an avenue for widespread antibiotic intake among the community. However, there is limited data on the antibiotic prescription appropriateness and resi...

DNA virus oncoprotein HPV18 E7 selectively antagonizes cGAS-STING-triggered innate immu...
https://doi.org/10.1002/jmv.28310
Journal of Medical Virology; Lou M, Huang D et. al.

Nov 16th, 2022 - Cellular infections by DNA viruses trigger innate immune responses mediated by DNA sensors. The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon gene (STING) signaling pathway has been identified as a DNA-sensing pathway that activates inte...

SENP1 Protects Against Pressure Overload-Induced Cardiac Remodeling and Dysfunction Via...
https://doi.org/10.1161/JAHA.122.027004
Journal of the American Heart Association; Yang D, Fan D et. al.

Nov 13th, 2022 - Background SENP1 (sentrin/small ubiquitin-like modifier-specific protease 1) has emerged as a significant modulator involved in the pathogenesis of a variety of human diseases, especially cancer. However, the regulatory roles of SENP1 in cardiovas...

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Guidelines  1 results

Community acquired respiratory virus infections in cancer patients-Guideline on diagnos...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125955
European Journal of Cancer (Oxford, England : 1990); von Lilienfeld-Toal M, Berger A et. al.

Sep 30th, 2016 - Community acquired viruses (CRVs) may cause severe disease in cancer patients. Thus, efforts should be made to diagnose CRV rapidly and manage CRV infections accordingly. A panel of 18 clinicians from the Infectious Diseases Working Party of the G...

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Drugs  15 results see all →

Clinicaltrials.gov  404 results

Follow-Up Evaluation for Gene-Therapy-Related Delayed Adverse Events After Participation in Pediatric Oncology Branch Clinical Trials
https://clinicaltrials.gov/ct2/show/NCT02315599

Oct 14th, 2022 - Background: Study subjects exposed to gene therapy interventions may be at risk for delayed or longterm adverse consequences. The U.S. Food and Drug Administration (FDA) has issued Long Term Follow-up After Administration of Human Gene Therapy Pro...

Gene Therapy Study in Severe Haemophilia A Patients (270-201)
https://clinicaltrials.gov/ct2/show/NCT02576795

Oct 14th, 2022 - This study is being conducted by BioMarin Pharmaceutical Inc. as an open label, dose escalation study in order to determine the safety and efficacy of valoctocogene roxaparvovec (an Adenovirus-Associated Virus based gene therapy vector in particip...

Ad26.ZEBOV, MVA-BN-Filo Vaccination in Children and Adults Previously Vaccinated With Control in the EBOVAC-Salone Study
https://clinicaltrials.gov/ct2/show/NCT05284097

Oct 14th, 2022 - This study is being conducted to assess the safety and immunogenicity of the Ad26.ZEBOV (Dose 1), MVA-BN-Filo (Dose 2) vaccine regimen, administered with a 56-day interval between the two doses, in adults and children previously enrolled in the co...

Gene Therapy Study in Severe Hemophilia A Patients With Antibodies Against AAV5
https://clinicaltrials.gov/ct2/show/NCT03520712

Oct 14th, 2022 - This study is being conducted by BioMarin Pharmaceutical Inc. as an open label, single dose study to determine the safety of valoctocogene roxaparvovec (an Adenovirus-Associated Virus (AAV) based gene therapy vector) in severe Hemophilia A patient...

Phase 1 Trial of ChAd68 and Ad5 Adenovirus COVID-19 Vaccines Delivered by Aerosol
https://clinicaltrials.gov/ct2/show/NCT05094609

Oct 12th, 2022 - This is a phase 1, dose-escalating study to evaluate the safety and immunogenicity of a single dose of either Ad5-triCoV/Mac, a replication deficient human adenovirus vector, or ChAd-triCoV/Mac, a replication deficient chimpanzee adenovirus 68 vec...

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News  424 results

Sick Call
https://www.medscape.com/viewarticle/984535

Nov 23rd, 2022 - They call me and I go. – William Carlos Williams I never get sick. I've never had the flu. When everyone's got a cold, I'm somehow immune. The last time I threw up was June 29th, 1980. You see, I work out almost daily, eat vegan, and sleep plenty....

Most Pediatric Myocarditis Caused by Viruses
https://www.medscape.com/viewarticle/982609

Oct 18th, 2022 - ANAHEIM — A wide range of factors can cause myocarditis; most often viral infections cause myocarditis in children and teens, according to Ryan Butts, MD, medical director of the pediatric advanced cardiac care program at the University of Texas S...

EMA Grants Orphan Drug Designation to CAN-2409 for Glioma
https://www.onclive.com/view/ema-grants-orphan-drug-designation-to-can-2409-for-glioma

Sep 16th, 2022 - The European Medicines Agency (EMA) Committee for Orphan Medical Products has granted an orphan drug designation (ODD) to CAN-2409 for the treatment of patients with glioma, according to an announcement from Candel Therapeutics.1 CAN-2409 is a ...

China, India Approve Nasal COVID Vaccines
https://www.medscape.com/viewarticle/980366

Sep 7th, 2022 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. China and India have approved COVID-19 vaccines that can be given through the nose or mouth, which scientists hope will be a "game changer" for th...

CanSino's Inhaled COVID-19 Vaccine Gets Emergency Use Approval in China
https://www.medscape.com/viewarticle/980221

Sep 6th, 2022 - HONG KONG (Reuters) - China's CanSino Biologics Inc said on Sunday that its recently developed COVID-19 vaccine has been approved by the country's drug regulator for emergency use as a booster, potentially benefiting its business. The inhaled vers...

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Patient Education  11 results see all →