About 475 results

ALLMedicine™ Arenaviruses Center

Research & Reviews  188 results

Abalos Therapeutics---arenaviruses take on cancer.
Nature Biotechnology; DeFrancesco L

Aug 13th, 2022 - Abalos Therapeutics---arenaviruses take on cancer.|2022|DeFrancesco L,|

Influenza Differential Diagnoses

Aug 10th, 2022 - Diagnostic Considerations Accurately diagnosing influenza A or B infection solely on the basis of clinical criteria is difficult because of the overlapping symptoms caused by the various viruses associated with upper respiratory tract infection (U...

Evaluating the Biological Role of Lassa Viral Z Protein-Mediated RIG-I Inhibition Using...
Journal of Virology; Di D, Huang Q et. al.

Aug 2nd, 2022 - Lassa virus (LASV) is a mammarenavirus that can cause lethal Lassa fever disease with no FDA-approved vaccine and limited treatment options. Fatal LASV infections are associated with innate immune suppression. We have previously shown that the sma...

Potential and action mechanism of favipiravir as an antiviral against Junin virus.
PLoS Pathogens; Zadeh VR, Afowowe TO et. al.

Jul 12th, 2022 - Favipiravir is a nucleoside analogue that inhibits the replication and transcription of a broad spectrum of RNA viruses, including pathogenic arenaviruses. In this study, we isolated a favipiravir-resistant mutant of Junin virus (JUNV), which is t...

Cell surface glycan engineering reveals that matriglycan alone can recapitulate dystrog...
Nature Communications; Sheikh MO, Capicciotti CJ et. al.

Jun 25th, 2022 - α-Dystroglycan (α-DG) is uniquely modified on O-mannose sites by a repeating disaccharide (-Xylα1,3-GlcAβ1,3-)n termed matriglycan, which is a receptor for laminin-G domain-containing proteins and employed by old-world arenaviruses for infection. ...

see more →

Clinicaltrials.gov  1 results

Favipiravir vs Hydroxychloroquine vs Control in COVID -19

Oct 26th, 2021 - Coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2/2019-nCoV) and has developed into a pandemic with serious global public health and economic sequelae. As of June 30, 2020 over 10,000,...

see more →

News  1 results

Global Ebola—Are We Prepared?
Carol McCammon Md, MPH, Benjamin Chidester, MD

Oct 1st, 2014 - In this age of globalization, just a few hours of air travel separates even the most remote places in our world. Given this reality, the recent epidemic of Ebola virus disease (EVD) in West Africa (Figure 1) has arrived on the doorstep of Texas He.

see more →