ALLMedicine™ Botulism Center

Jan 25th, 2023 - Infant botulism (IB) is an intestinal toxemia that manifests as descending paralysis, constipation, and, in some cases, respiratory failure. Laboratory-confirmed IB cases are rare, and recent data in Israel are lacking. We conducted a national mul...

Dec 24th, 2022 - Botulism in emergency department.|2022|Barbato F,Allocca R,Altruda C,Caterino V,Numis FG,|

Dec 21st, 2022 - This article reviews the pathophysiology, epidemiology, clinical features, diagnosis, and treatment of Lambert-Eaton myasthenic syndrome (LEMS) and botulism, presynaptic disorders of neuromuscular transmission in which rapid diagnosis improves lon...

Dec 7th, 2022 - Practice Essentials Botulism is an acute neurologic disorder that causes potentially life-threatening paralysis due to a neurotoxin produced by Clostridium botulinum or related species (C baratii and C. butyricum). Exposure may occur via 4 routes ...

Dec 7th, 2022 - Medication Summary Antibiotics are useful in wound botulism, but they have no role in foodborne botulism. Next: Antibiotics Class Summary When botulism develops following a wound infection, antibiotic therapy and meticulous debridement of the woun...

Nov 25th, 2022 - Primary Objective: To collect blood from pediatric participants to analyze the pharmacokinetics (PK) of BAT product to verify the current US FDA-approved pediatric dosing recommendations for BAT product. Safety Objective: To evaluate the safety of...

Jul 25th, 2022 - Over fifty percent of stroke patients experience chronic arm hand performance problems, compromising independence in daily life activities and quality of life. Traditionally, the effectiveness of rehabilitation in improving functioning for stroke ...

Dec 13th, 2021 - Hailey Hailey and Darier disease are rare genetic dermatoses. Mutations of 2 genes (ATP2C1 or ATP2A2 respectively) are responsible for the diseases. These genes have a key role in calcium pump; their defect create abnormal link between keratinocyt...

Jul 29th, 2021 - Clinical characteristics of impaired motor performance on affected upper extremity in stroke patients included muscle weakness, increased muscle tone, contracture, joint instability, or impaired motor control. Poststroke spasticity (PSS) is also a...

Feb 17th, 2021 - A full description of the patient registry can be found in the paper titled: Safety and Clinical Outcomes of an Equine-derived Heptavalent Botulinum Antitoxin Treatment for Confirmed or Suspected Botulism in the United States. Richardson JS, Parre...

cases indicate a stronger link to soil transmission, possible seasonal variation, and a milder course of disease.

Have you ever heard of a foodborne disease that causes paralysis? How can you prevent this from happening to you or your family?

May 20th, 2022 - Historical food-borne outbreaks of botulism and identification of Clostridium botulinum as the bacterium responsible have had an enormous impact in medicine related to its therapeutic and cosmetic uses. The timeline of botulinum toxin discovery be.

Dec 21st, 2021 - David Gerber, MD: Steve, it might be helpful at this point to go over how we diagnose and test for LEMS [Lambert-Eaton myasthenic syndrome]. Steven Vernino, MD, PhD: As neurologists, when we see conditions that make us think about paraneoplastic ...

Jun 1st, 2021 - Botulinum toxin is said to be the most lethal substance known. Inhaling just 1-3 nanograms of toxin per kilogram of body mass constitutes a lethal dose.  Now the Centers for Disease Control and Prevention (CDC) has published the first comprehensiv...