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About 17,435 results

ALLMedicine™ Cytomegalovirus Center

Research & Reviews  6,378 results

Cytomegalovirus antiviral stewardship in solid organ transplant recipients: A new gold ...
https://doi.org/10.1111/tid.13864
Transplant Infectious Disease : an Official Journal of Th... Jorgenson MR, Descourouez JL et. al.

May 24th, 2022 - Antimicrobial-stewardship-programs (ASPs) are essential entities that promote the appropriate use of antimicrobials, leading to improved patient outcomes and reduced resistance. Application to the immunocompromised host is a natural progression fo...

BacMam Expressing Highly Glycosylated Porcine Interferon Alpha Induces Robust Antiviral...
https://doi.org/10.1128/jvi.00528-22
Journal of Virology; Kim A, Lee G et. al.

May 24th, 2022 - Foot-and-mouth disease (FMD) is an acute contagious disease that affects cloven-hoofed animals and has severe global economic consequences. FMD is most commonly controlled by vaccination. Currently available commercial FMD vaccines contain chemica...

Incidence and risk factors for the development of cytomegalovirus viremia in a steroid ...
https://doi.org/10.1111/tid.13867
Transplant Infectious Disease : an Official Journal of Th... Viehl E, Lichvar A et. al.

May 24th, 2022 - Cytomegalovirus (CMV) is a common opportunistic infection in patients after liver transplant (LT). Guidelines recommend 900mg daily of valganciclovir, however, valganciclovir commonly causes dose-dependent hematologic toxicities. Use of a low-dose...

Polyploid giant cancer cells, EZH2 and Myc upregulation in mammary epithelial cells inf...
https://doi.org/10.1016/j.ebiom.2022.104056
EBioMedicine Nehme Z, Pasquereau S et. al.

May 22nd, 2022 - Human cytomegalovirus (HCMV) infection has been actively implicated in complex neoplastic processes. Beyond oncomodulation, the molecular mechanisms that might underlie HCMV-induced oncogenesis are being extensively studied. Polycomb repressive co...

A Study of Safety and Immune Response to Different Doses of a Cytomegalovirus Vaccine in Healthy Adults
https://clinicaltrials.gov/ct2/show/NCT05089630

May 20th, 2022 - The purpose of this study is to assess the safety, reactogenicity and immunogenicity of the candidate CMV recombinant protein subunit (CMVsu) vaccine consisting of a combination of glycoproteins B (gB) and pentamer antigens adjuvanted, regardless ...

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Guidelines  10 results

Cytomegalovirus serological testing in potential allogeneic haematopoietic stem cell tr...
https://doi.org/10.1111/bjh.17754
British Journal of Haematology; Morton S, Dignan F et. al.

Aug 18th, 2021 - Cytomegalovirus serological testing in potential allogeneic haematopoietic stem cell transplant recipients: A British Society for Haematology Good Practice Paper.|2021|Morton S,Dignan F,Osman H,Potter M,Pagliuca T,|blood,immunology,diagnosis,preve...

Society for Maternal-Fetal Medicine Consult Series #57: Evaluation and management of is...
https://doi.org/10.1016/j.ajog.2021.06.079
American Journal of Obstetrics and Gynecology; , Prabhu M et. al.

Jun 26th, 2021 - Soft markers were originally introduced to prenatal ultrasonography to improve the detection of trisomy 21 over that achievable with age-based and serum screening strategies. As prenatal genetic screening strategies have greatly evolved in the las...

Guideline No. 420: Cytomegalovirus Infection in Pregnancy.
https://doi.org/10.1016/j.jogc.2021.05.015
Journal of Obstetrics and Gynaecology Canada : JOGC = Jou... Boucoiran I, Yudin M et. al.

Jun 6th, 2021 - To provide an update on current recommendations for cytomegalovirus (CMV) infection during pregnancy. The objectives of this guideline are: TARGET POPULATION: Patients of child-bearing age, pregnant patients, and patients planning a pregnancy. The...

The Third International Consensus Guidelines on the Management of Cytomegalovirus in So...
https://doi.org/10.1097/TP.0000000000002191
Transplantation Kotton CN, Kumar D et. al.

Mar 30th, 2018 - Despite recent advances, cytomegalovirus (CMV) infections remain one of the most common complications affecting solid organ transplant recipients, conveying higher risks of complications, graft loss, morbidity, and mortality. Research in the field...

No. 240-Cytomegalovirus Infection in Pregnancy.
https://doi.org/10.1016/j.jogc.2017.11.018
Journal of Obstetrics and Gynaecology Canada : JOGC = Jou... Yinon Y, Farine D et. al.

Feb 16th, 2018 - To review the principles of prenatal diagnosis of congenital cytomegalovirus (CMV) infection and to describe the outcomes of the affected pregnancies. Effective management of fetal infection following primary and secondary maternal CMV infection d...

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Drugs  81 results see all →

Clinicaltrials.gov  175 results

A Study of Safety and Immune Response to Different Doses of a Cytomegalovirus Vaccine in Healthy Adults
https://clinicaltrials.gov/ct2/show/NCT05089630

May 20th, 2022 - The purpose of this study is to assess the safety, reactogenicity and immunogenicity of the candidate CMV recombinant protein subunit (CMVsu) vaccine consisting of a combination of glycoproteins B (gB) and pentamer antigens adjuvanted, regardless ...

Haploidentical Donor CMV Specific CTL to Treat CMV Reactivation or Infection After Solid Organ & HCT
https://clinicaltrials.gov/ct2/show/NCT03665675

Apr 28th, 2022 - PRIMARY OBJECTIVE I. Assess the safety and feasibility of administering high-throughput antigen stimulation/interferon gamma capture system (Miltenyi Biotec, CliniMACS Prodigy System) generated CMV specific- CTLs from haploidentical donors in tran...

Cytomegalovirus (CMV) Perilymphatic Fluid
https://clinicaltrials.gov/ct2/show/NCT04724265

Apr 18th, 2022 - Data on etiology of hearing loss and CMV status are collected. Perilymphatic liquid is collected after cochleostomy using a 1ml seringue. The drop of liquid is deposited on a Guthrie card; on another card, a drop of blood is deposited on another c...

Impact of Anti-cytomegalovirus Treatment in the Management of Relapsing Ulcerative Colitis Requiring Vedolizumab Therapy
https://clinicaltrials.gov/ct2/show/NCT04064697

Apr 12th, 2022 - The hypothesis of this study is in Ulcerative Colitis (UC) patients with tissue CytoMegaloVirus (CMV) reactivation ; not responding to anti-TNF or without anti-TNF ; a treatment with valganciclovir, added to vedolizumab, could improve the clinical...

A Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1647 Cytomegalovirus (CMV) Vaccine in Healthy Participants 16 to 40 Years of Age
https://clinicaltrials.gov/ct2/show/NCT05085366

Apr 12th, 2022 - The main purpose of this study is to evaluate the efficacy of mRNA 1647 vaccine in CMV-seronegative female participants and to evaluate the safety and reactogenicity of mRNA-1647 vaccine in all participants.

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News  321 results

Porcine Virus a Suspect in Man's Death After Pig Heart Transplant
https://www.medscape.com/viewarticle/973463

May 5th, 2022 - The heart from a genetically modified pig transplanted to a Maryland patient in January in a pioneering, acclaimed, and widely critiqued surgery appears to have carried an unwanted passenger. A porcine cytomegalovirus (PCMV) in the heart had gone ...

FDA Approvals, Highlights, and Summaries: Infectious Disease
https://www.medscape.com/viewarticle/967609

Feb 17th, 2022 - Livtencity (maribavir) Maribavir is an antiviral that elicits its activity by competitive inhibition of the protein kinase activity of human cytomegalovirus (CMV) enzyme pUL97, which inhibits protein phosphorylation. It is indicated for treatment ...

FDA Approvals, Highlights, and Summaries: Pediatrics
https://www.medscape.com/viewarticle/967615

Feb 17th, 2022 - Infectious Disease Livtencity (maribavir) Maribavir is an antiviral that elicits its activity by competitive inhibition of the protein kinase activity of human cytomegalovirus (CMV) enzyme pUL97, which inhibits protein phosphorylation. It is indic...

FDA Approvals, Highlights, and Summaries: Infectious Disease
https://reference.medscape.com/viewarticle/967609

Feb 17th, 2022 - Livtencity (maribavir) Maribavir is an antiviral that elicits its activity by competitive inhibition of the protein kinase activity of human cytomegalovirus (CMV) enzyme pUL97, which inhibits protein phosphorylation. It is indicated for treatment ...

Skill Checkup: A Man Who Had Autologous Hematopoietic Stem Cell Transplantation Developed Acute Graft-vs-Host Disease
https://reference.medscape.com/viewarticle/965260

Feb 10th, 2022 - The Skill Checkup series provides a quick, case-style interactive quiz highlighting key guidelines- and evidence-based information to inform clinical practice. A 46-year-old man was diagnosed with acute myeloid leukemia 1 year ago. He was treated ...

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Patient Education  9 results see all →