About 22,063 results

ALLMedicine™ Cytomegalovirus Center

Research & Reviews  7,671 results

The X-linked epigenetic regulator UTX controls NK cell-intrinsic sex differences.
Nature Immunology; Cheng MI, Li JH et. al.

Mar 18th, 2023 - Viral infection outcomes are sex biased, with males generally more susceptible than females. Paradoxically, the numbers of antiviral natural killer (NK) cells are increased in males. We demonstrate that while numbers of NK cells are increased in m...

Clinical phenotypes and prognosis of cytomegalovirus infection in the pediatric systemi...
Pediatric Rheumatology Online Journal; Zhang T, Yu Z et. al.

Mar 18th, 2023 - Cytomegalovirus (CMV) plays an important role in the pathogenesis of systemic lupus erythematosus (SLE). However, it is not clear whether the anti-CMV treatment has an impact on the prognosis of SLE patients with CMV infection. We aimed to analyze...

Esophageal ulcer related to zinc deficiency following a total gastrectomy.
Nutrition (Burbank, Los Angeles County, Calif.); Hayashi A, Taki Y et. al.

Mar 17th, 2023 - A 76-y-old Japanese man who had undergone gastrectomy 4.5 y earlier experienced 2 wk of sore throat, heartburn, and difficulty swallowing. Endoscopy showed deep, craterlike, longitudinal ulcers in the lower and middle esophagus. Immunohistochemist...

Cytomegalovirus serology in young to mid-adult life and decline of lung function.
The Clinical Respiratory Journal; Nenna R, Zhai J et. al.

Mar 17th, 2023 - Cytomegalovirus (CMV) seropositivity has been recently linked to severity and progression of asthma, cystic fibrosis, and chronic obstructive pulmonary disease (COPD). To date, no longitudinal study has addressed the relation of CMV serology to le...

First-line management of necrotizing herpetic retinitis by prioritizing the investigati...
International Ophthalmology; Loubsens E, Adam R et. al.

Mar 16th, 2023 - To review management, treatment, and outcomes of patients with necrotizing herpetic retinitis (NHR) to propose an algorithm for first-line management of NHR. Retrospective evaluation of a series of patients with NHR at our tertiary center between ...

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Guidelines  10 results

Cytomegalovirus serological testing in potential allogeneic haematopoietic stem cell tr...
British Journal of Haematology; Morton S, Dignan F et. al.

Aug 18th, 2021 - Cytomegalovirus serological testing in potential allogeneic haematopoietic stem cell transplant recipients: A British Society for Haematology Good Practice Paper.|2021|Morton S,Dignan F,Osman H,Potter M,Pagliuca T,|blood,immunology,diagnosis,preve...

Society for Maternal-Fetal Medicine Consult Series #57: Evaluation and management of is...
American Journal of Obstetrics and Gynecology; , Prabhu M et. al.

Jun 26th, 2021 - Soft markers were originally introduced to prenatal ultrasonography to improve the detection of trisomy 21 over that achievable with age-based and serum screening strategies. As prenatal genetic screening strategies have greatly evolved in the las...

Guideline No. 420: Cytomegalovirus Infection in Pregnancy.
Journal of Obstetrics and Gynaecology Canada : JOGC = Jou... Boucoiran I, Yudin M et. al.

Jun 6th, 2021 - To provide an update on current recommendations for cytomegalovirus (CMV) infection during pregnancy. The objectives of this guideline are: TARGET POPULATION: Patients of child-bearing age, pregnant patients, and patients planning a pregnancy. The...

The Third International Consensus Guidelines on the Management of Cytomegalovirus in So...
Transplantation Kotton CN, Kumar D et. al.

Mar 30th, 2018 - Despite recent advances, cytomegalovirus (CMV) infections remain one of the most common complications affecting solid organ transplant recipients, conveying higher risks of complications, graft loss, morbidity, and mortality. Research in the field...

No. 240-Cytomegalovirus Infection in Pregnancy.
Journal of Obstetrics and Gynaecology Canada : JOGC = Jou... Yinon Y, Farine D et. al.

Feb 16th, 2018 - To review the principles of prenatal diagnosis of congenital cytomegalovirus (CMV) infection and to describe the outcomes of the affected pregnancies. Effective management of fetal infection following primary and secondary maternal CMV infection d...

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Drugs  96 results see all →

Clinicaltrials.gov  518 results

Novel Genetic Disorders of the Immune System

Mar 10th, 2023 - This study is designed to evaluate patients with suspected or identified novel immune disorders, with a focus on abnormal immune homeostasis potentially due to defects in activation or apoptosis. Blood relatives of enrolled patients will also be e...

Dried Blood Spot Testing of CMV Detection in HCT Recipients

Mar 10th, 2023 - This is a randomized clinical trial to assess whether a subject centered, self-collection of Dried blood spots (DBS) samples will improve compliance with the clinical recommendation of weekly Cytomegalovirus (CMV) testing of Hematopoietic cell tra...

A Study of Letermovir (MK-8228) to Evaluate Efficacy and Safety for Prevention of CMV Infection in Chinese Hematopoietic Stem Cell Transplant Recipients (MK-8228-045)

Mar 10th, 2023 - The purpose of this study is to evaluate the efficacy and safety of once-a-day orally or IV dose of Letermovir (MK-8228) in Chinese adult Hematopoietic Stem Cell Transplant (HSCT) recipients for the prevention of clinically significant Cytomegalov...

Letermovir Treatment for Refractory or Resistant Cytomegalovirus Infection

Mar 8th, 2023 - This is a Phase II clinical trial. Phase II clinical trials test the safety and effectiveness of an investigational drug to learn whether the drug works in treating a specific disease. "Investigational" means that the drug is being studied. The FD...

rATG Induction and Tacrolimus Monotherapy in Pediatric Liver Transplantation

Mar 7th, 2023 - This open-label clinical trial will evaluate the pharmacodynamics, pharmacogenomics and early efficacy and safety of steroid-free Tacrolimus (TAC) monotherapy and its minimization after induction with rabbit, anti-human thymocyte globulin (rATG, G...

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News  511 results

Palmar rash
MDedge Family Medicine;

Jan 31st, 2023 - This patient’s targetoid and tingling skin lesions, in association with herpes simplex virus (HSV) infection, are a classic presentation of erythema multiforme (EM). EM is an acute, self-limited, immune-mediated process that most commonly arises i.

Off-the-Shelf T-Cell Therapy Effective Against Viral Infections After Allo-HCT

Jan 13th, 2023 - An investigational, off-the-shelf T-cell therapy appears to be effective against six different viral infections that are common in patients who undergo allogeneic hematopoietic cell transplantation (HCT), according to results from a phase II trial...

Early Win for Gene Therapy in Rare Form of SCID

Dec 21st, 2022 - A gene therapy for a rare type of severe combined immunodeficiency (SCID) was safe and sufficiently restored T-cell immunity in an early trial, results from a phase I/II study showed. At a single center, all 10 infants with Artemis-deficient SCID ...

CDC Details Rabies Death After Boy Goes Untreated Following Bat Bite

Dec 9th, 2022 - Public health officials released details on how a 7-year-old boy from Texas died from a rare rabies infection last year. Although the boy had informed his parents he had been bitten by a bat while playing outside his apartment home, there were no ...

Moderna Exec Says COVID Trials Improved Diversity Recruiting

Dec 1st, 2022 - NEW YORK (Reuters) - Moderna Inc's top scientist said on Tuesday that the vaccine maker has learned how to better recruit from diverse populations for its clinical trials from running its COVID-19 vaccine studies. Moderna Chief Medical Officer Pau...

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Patient Education  19 results see all →