About 4,583 results

ALLMedicine™ Epstein-barr Virus Center

Research & Reviews  1,808 results

Programmed death 1 monoclonal antibody helped to treat mixed chimeric and reactivation ...
Medicine You Y, Wang J et. al.

Jan 15th, 2022 - Systemic forms of chronic active Epstein-Barr virus infection (CAEBV) can predispose a patient to a protracted course of fulminant hemophagocytic lymphohistiocytosis, which has a poor prognosis. Epstein-Barr virus (EBV) infection may persist even ...

EBV+ tumors exploit tumor cell-intrinsic and -extrinsic mechanisms to produce regulator...
PLoS Pathogens; Jorapur A, Marshall LA et. al.

Jan 14th, 2022 - The Epstein-Barr Virus (EBV) is involved in the etiology of multiple hematologic and epithelial human cancers. EBV+ tumors employ multiple immune escape mechanisms, including the recruitment of immunosuppressive regulatory T cells (Treg). Here, we...

EBV LMP1-activated mTORC1 and mTORC2 Coordinately Promote Nasopharyngeal Cancer Stem Ce...
Journal of Virology; Zhu N, Wang Q et. al.

Jan 13th, 2022 - Epstein-Barr Virus (EBV) is associated with several malignant diseases, including Burkitt's lymphoma, nasopharyngeal carcinoma (NPC), certain types of lymphomas, and a portion of gastric cancers. Virus-encoded oncoprotein LMP1 induces the epitheli...

Analysis of antibody binding specificities in twin and SNP-genotyped cohorts reveals th...
Immunity Venkataraman T, Valencia C et. al.

Jan 13th, 2022 - Human immune responses to viral infections are highly variable, but the genetic factors that contribute to this variability are not well characterized. We used VirScan, a high-throughput epitope scanning technology, to analyze pan-viral antibody r...

Epstein-Barr Virus BGLF2 commandeers RISC to interfere with cellular miRNA function.
PLoS Pathogens; Campbell AM, De La Cruz Herrera CF et. al.

Jan 11th, 2022 - The Epstein-Barr virus (EBV) BGLF2 protein is a tegument protein with multiple effects on the cellular environment, including induction of SUMOylation of cellular proteins. Using affinity-purification coupled to mass-spectrometry, we identified th...

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Drugs  10 results see all →

News  14 results

Epstein-Barr Virus a Likely Leading Cause of Multiple Sclerosis

Jan 14th, 2022 - Epstein-Barr virus (EBV) is the likely cause of multiple sclerosis (MS), new research confirms. Investigators found the risk of MS increased 32-fold following EBV infection. Dr Alberto Ascherio This study is the first to provide compelling evidenc...

Schizophrenia patients have ‘aberrant’ response to Epstein-Barr
Christopher Palmer

Oct 15th, 2019 - Individuals with schizophrenia had elevated levels of one Epstein-Barr virus (EBV) antibody but atypically low levels of another, which investigators deemed an “aberrant immune response. ” Faith Dickerson, PhD, MPH, Lorraine Jones-Brando, PhD,and c.

Vitamin D Boosts, Smoking Clouds Cognition in MS

Oct 15th, 2018 - BERLIN — Higher vitamin D levels at the time of a diagnosis of a clinically isolated syndrome (CIS) were associated with better cognitive performance 11 years later. In contrast, cigarette smoking was linked to worse long-term cognition. Seroposit...

Study supports link between pediatric MS and remote viral infections
Sharon Worcester

May 17th, 2017 - BOSTON – Prior Epstein-Barr virus (EBV) infection and prior herpes simplex virus (HSV) infection each appear to be associated with development of pediatric-onset multiple sclerosis (MS), according to findings from a large national case-control stu.

T Cells Targeting Epstein-Barr Virus -- A New Treatment for MS?

Apr 26th, 2017 - BOSTON — A new approach to the treatment of multiple sclerosis (MS) — use of T cells sensitized to the Epstein-Barr virus — has shown encouraging results in a preliminary study. The study, presented at the American Academy of Neurology 2017 Annual...

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Patient Education  1 results see all →