ALLMedicine™ Influenza Center

Mar 18th, 2023 - Conventional influenza vaccines focus on hemagglutinin (HA). However, antibody responses to neuraminidase (NA) have been established as an independent correlate of protection. Here, we introduced the ectodomain of NA into DNA vaccines that as tran...

Mar 18th, 2023 - Influenza and Respiratory Syncytial virus (RSV) infections together contribute significantly to the burden of acute lower respiratory tract infections. Despite the disease burden, no approved RSV vaccine is available. While approved vaccines are a...

Mar 18th, 2023 - Epiglottitis is a bacterial infection of the upper respiratory tract that can be rapidly progressive and life-threatening. Though predominantly seen in unvaccinated children, there seems to be a shift with the incidence of adult cases rising follo...

Mar 18th, 2023 - Uptake of influenza, pneumococcal and shingles vaccines in older adults vary across regions and socioeconomic backgrounds. In this study, we study the coverage and factors associated with vaccination uptake, as well as refusal in the unvaccinated ...

Mar 18th, 2023 - Regulatory T (Treg) cells are an immunosuppressive population that are required to maintain peripheral tolerance and prevent tissue damage from immunopathology, via anti-inflammatory cytokines, inhibitor receptors and metabolic disruption. Here we...

Mar 13th, 2023 - In an updated assessment on H5N1 avian influenza, European health groups said though the risk to humans is still low, worrisome signs include the appearance of certain mutations in circulating strains and mass animal mortality events that hint at ...

Mar 13th, 2023 - Between 3 December 2022 and 1 March 2023 highly pathogenic avian influenza (HPAI) A(H5N1) virus, clade 2.3.4.4b, was reported in Europe in domestic (522) and wild (1,138) birds over 24 countries. An unexpected number of HPAI virus detections in se...

Feb 24th, 2023 - The Lucira COVID-19 & Flu Home Test is a single use (disposable) home test kit intended for simultaneous rapid in vitro qualitative detection and differentiation of SARS-CoV-2, influenza A, and influenza B viral nucleic acid. This test is autho...

Feb 20th, 2023 - Cardiovascular disease (CVD) is the leading cause of death in the world and is largely preventable. An increasing amount of evidence suggests that annual influenza vaccination reduces CVD-related morbidity and mortality. Despite various clinical g...

Feb 14th, 2023 - The link between influenza and medical complications is well stablished and plays a role in the high mortality rates of this disease. Available scientific evidence suggests that influenza vaccination might reduce the risk of cardiovascular events.

Mar 17th, 2023 - The COVID-19 pandemic, caused by the coronavirus SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), has infected a substantial portion of the world population, leading to millions of deaths since its first description in December of 201...

Mar 14th, 2023 - It has been demonstrated that respiratory virus outbreaks and pandemics, such as influenza, SARS, MERS, and now the newly emerged SARS-COV2 virus, have a major impact on morbidity and mortality worldwide, as well as having devastating global econo...

Mar 13th, 2023 - In an updated assessment on H5N1 avian influenza, European health groups said though the risk to humans is still low, worrisome signs include the appearance of certain mutations in circulating strains and mass animal mortality events that hint at ...

Mar 13th, 2023 - Between 3 December 2022 and 1 March 2023 highly pathogenic avian influenza (HPAI) A(H5N1) virus, clade 2.3.4.4b, was reported in Europe in domestic (522) and wild (1,138) birds over 24 countries. An unexpected number of HPAI virus detections in se...

Mar 10th, 2023 - Study Description: This is a dose-finding and pathogenicity study following human challenge with a low pathogenicity avian influenza A H10N7. Participants will be inoculated with 1 dose of challenge virus during the study and then followed for a m...

Since 2022, despite the wide geographic spread of highly pathogenic avian influenza (HPAI) A(H5N1) viruses in wild birds and to poultry worldwide, with sporadic spillover to mammals, only a small number of sporadic human cases of A(H5N1) have been...

Like much of the rest of the world, the United States continues to experience outbreaks of highly pathogenic avian influenza (HPAI) A(H5N1) virus in wild birds and poultry.

Human infections with avian influenza A viruses are uncommon but have occurred sporadically in many countries, usually after unprotected exposures (e.g. not using respiratory or eye protection) to infected poultry or virus-contaminated environment...

The timeline gives a summary of significant HPAI and LPAI outbreaks in birds, infections in people, and events from 2020-2023.

Two human infections with avian influenza A H5N1 (H5N1 bird flu) have been reported by Cambodia.