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About 51,573 results

ALLMedicine™ Malaria Center

Research & Reviews  18,068 results

Screening of Healthy Volunteers for Investigational Antimalarial Drugs, Malaria Vaccines, and Controlled Human Malaria Challenge
https://clinicaltrials.gov/ct2/show/NCT02639299

Jul 1st, 2022 - This is a screening protocol for healthy volunteers to participate in research studies conducted by Laboratory of Malaria Immunology and Vaccinology (LMIV). Malaria-related morbidity and mortality have a major economic impact in endemic regions an...

rCSP/AP10-602 [GLA-LSQ] Vaccine Trial
https://clinicaltrials.gov/ct2/show/NCT03589794

Jul 1st, 2022 - This is a phase I, single-site, dose escalation study to evaluate the safety, immunogenicity, and efficacy of the recombinant circumsporozoite protein (rCSP) antigen malaria vaccine administered with and without AP 10-602 [Glucopyranosyl Lipid A (...

Combination of Trametinib (MEK Inhibitor) and Hydroxychloroquine (HCQ) (Autophagy Inhibitor) in Patients With KRAS Mutation Refractory Bile Tract Carcinoma (BTC).
https://clinicaltrials.gov/ct2/show/NCT04566133

Jul 1st, 2022 - Background: Among the new cases of bile tract carcinoma (BTC) that are diagnosed every year in the United States, there are approximately 6,500 cases of gallbladder carcinoma, 3,000 cases of extrahepatic cholangiocarcinoma, and 3,000 cases of intr...

Host and Parasite Factors That Influence Susceptibility to Malaria Infection and Disease During Pregnancy and Early Childhood in Ouelessebougou and Bamako, Mali
https://clinicaltrials.gov/ct2/show/NCT01168271

Jul 1st, 2022 - Malaria caused by Plasmodium falciparum continues to be a global problem with devastating consequences. A greater understanding of the immunologic and parasitologic factors associated with infection and disease is badly needed; and will accelerate...

Plasmodium and Other Parasites in Pregnant Women and Children Around Margibi and Montserrado Counties, Liberia
https://clinicaltrials.gov/ct2/show/NCT03719599

Jul 1st, 2022 - Malaria caused by Plasmodium falciparum continues to be a global problem with devastating consequences, in particular for at-risk populations such as pregnant women and young infants. Pregnancy malaria is associated with low birth weight (LBW), ma...

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Guidelines  4 results

Updated CDC Recommendations for Using Artemether-Lumefantrine for the Treatment of Unco...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898222
MMWR. Morbidity and Mortality Weekly Report; Ballard SB, Salinger A et. al.

Apr 13th, 2018 - Malaria infection during pregnancy is associated with an increased risk for maternal and fetal complications. In the United States, treatment options for uncomplicated, chloroquine-resistant Plasmodium falciparum and P. vivax malaria in pregnant w...

Guidelines for the Prevention and Treatment of Opportunistic Infections among HIV-expos...
https://www.ncbi.nlm.nih.gov/pubmed/19730409
MMWR. Recommendations and Reports : Morbidity and Mortali... Mofenson LM, Brady MT et. al.

Sep 5th, 2009 - This report updates and combines into one document earlier versions of guidelines for preventing and treating opportunistic infections (OIs) among HIV-exposed and HIV-infected children, last published in 2002 and 2004, respectively. These guidelin...

Guidance on the evaluation of Plasmodium vivax vaccines in populations exposed to natur...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844894
Vaccine Mueller I, Moorthy VS et. al.

Jul 30th, 2009 - In this paper we give guidance for the design and conduct of vaccine trials against Plasmodium vivax malaria. The paper supplements earlier guidelines on the planning of vaccine trials against Plasmodium falciparum malaria [WHO. Guidelines for the...

Treatment and prevention of malaria in pregnancy and newborn.
https://doi.org/10.1515/JPM.2008.002
Journal of Perinatal Medicine; Coll O, Menendez C et. al.

Jan 11th, 2008 - Pregnant women are at increased risk for malaria infection. Although important advances have been made in the last years, the mechanisms that explain the increased susceptibility are not yet fully understood. Malaria infection in pregnancy is asso...

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Drugs  217 results see all →

Clinicaltrials.gov  1,349 results

Screening of Healthy Volunteers for Investigational Antimalarial Drugs, Malaria Vaccines, and Controlled Human Malaria Challenge
https://clinicaltrials.gov/ct2/show/NCT02639299

Jul 1st, 2022 - This is a screening protocol for healthy volunteers to participate in research studies conducted by Laboratory of Malaria Immunology and Vaccinology (LMIV). Malaria-related morbidity and mortality have a major economic impact in endemic regions an...

rCSP/AP10-602 [GLA-LSQ] Vaccine Trial
https://clinicaltrials.gov/ct2/show/NCT03589794

Jul 1st, 2022 - This is a phase I, single-site, dose escalation study to evaluate the safety, immunogenicity, and efficacy of the recombinant circumsporozoite protein (rCSP) antigen malaria vaccine administered with and without AP 10-602 [Glucopyranosyl Lipid A (...

Combination of Trametinib (MEK Inhibitor) and Hydroxychloroquine (HCQ) (Autophagy Inhibitor) in Patients With KRAS Mutation Refractory Bile Tract Carcinoma (BTC).
https://clinicaltrials.gov/ct2/show/NCT04566133

Jul 1st, 2022 - Background: Among the new cases of bile tract carcinoma (BTC) that are diagnosed every year in the United States, there are approximately 6,500 cases of gallbladder carcinoma, 3,000 cases of extrahepatic cholangiocarcinoma, and 3,000 cases of intr...

Host and Parasite Factors That Influence Susceptibility to Malaria Infection and Disease During Pregnancy and Early Childhood in Ouelessebougou and Bamako, Mali
https://clinicaltrials.gov/ct2/show/NCT01168271

Jul 1st, 2022 - Malaria caused by Plasmodium falciparum continues to be a global problem with devastating consequences. A greater understanding of the immunologic and parasitologic factors associated with infection and disease is badly needed; and will accelerate...

Plasmodium and Other Parasites in Pregnant Women and Children Around Margibi and Montserrado Counties, Liberia
https://clinicaltrials.gov/ct2/show/NCT03719599

Jul 1st, 2022 - Malaria caused by Plasmodium falciparum continues to be a global problem with devastating consequences, in particular for at-risk populations such as pregnant women and young infants. Pregnancy malaria is associated with low birth weight (LBW), ma...

see more →

News  971 results

AI May Help Clinicians Differentiate Between Tropical Diseases
https://www.medscape.com/viewarticle/976446

Jul 1st, 2022 - (Reuters Health) - Artificial intelligence may help clinicians tell the difference between different tropical diseases, a new study suggests. Researchers used data from 800 patients to develop a machine learning tool that may aid in early discrimi...

Mosquitoes Go Viral if They Smell This on You
https://www.medscape.com/viewarticle/976205

Jun 30th, 2022 - This transcript has been edited for clarity. Welcome to Impact Factor, your weekly dose of commentary on a new medical study. I'm Dr F. Perry Wilson of the Yale School of Medicine. As the nights get warmer here in Connecticut, I'm spending more an...

GSK, Novartis Pledge Funds for Neglected Tropical Diseases
https://www.medscape.com/viewarticle/976095

Jun 24th, 2022 - LONDON (Reuters) - GSK and Novartis reinforced commitments on Thursday to tackle neglected tropical diseases, as world leaders and health experts gather in Rwanda to discuss ways to better combat illnesses affecting more than a billion people, mos...

Visa Delays a Worry for International AIDS Conference in Montreal
https://www.medscape.com/viewarticle/975984

Jun 21st, 2022 - Canadian visa delays are casting a shadow over preparations for the upcoming 24th International AIDS Society (IAS) Conference scheduled to begin in Montreal July 29. Jean-Pierre Routy, MD, local cochair of the meeting, has predicted "a catastrophe...

It’s hot outside – and that’s bad news for children’s health
https://www.mdedge.com/pediatrics/article/255536/injuries/its-hot-outside-and-thats-bad-news-childrens-health
Colleen Deguzman, Kaiser Health News

Jun 17th, 2022 - Heat waves are getting hotter and becoming more frequent because of rising rates of air pollution, putting children’s health at risk, a wide-ranging new report finds. An article in the New England Journal of Medicine reviews current research to ta.

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Patient Education  20 results see all →