×
About 25,576 results

ALLMedicine™ Epilepsy Center

Research & Reviews  11,759 results

The functional connectivity study on the brainstem-cortical/subcortical structures in r...
https://doi.org/10.1002/jdn.10064
International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience; Zhu J, Wang J et. al.

Sep 15th, 2020 - Cervical vagus nerve stimulation (VNS) is an effective neuromodulation therapy for patients with drug-resistant epilepsy (DRE). The previous studies reported that VNS may reduce seizures by regulating the functional connectivity (FC) between corti...

Impaired State-Dependent Potentiation of GABAergic Synaptic Currents Triggers Seizures ...
https://doi.org/10.1093/cercor/bhaa256
Cerebral Cortex (New York, N.Y. : 1991); Zhang CQ, Catron MA et. al.

Sep 15th, 2020 - Epileptic activity in genetic generalized epilepsy (GGE) patients preferentially appears during sleep and its mechanism remains unknown. Here, we found that sleep-like slow-wave oscillations (0.5 Hz SWOs) potentiated excitatory and inhibitory syna...

Etiology-related degree of sprouting of parvalbumin-immunoreactive axons in the human d...
https://doi.org/10.1016/j.neuroscience.2020.09.018
Neuroscience Ábrahám H, Molnár JE et. al.

Sep 15th, 2020 - In the present study, we examined parvalbumin-immunoreactive cells and axons in the dentate gyrus of surgically resected tissues of therapy-resistant temporal lobe epilepsy (TLE) patients with different etiologies. Based on MRI results, five group...

Effects of eslicarbazepine as add-on therapy on sleep architecture in temporal lobe epi...
https://doi.org/10.1016/j.sleep.2020.06.033
Sleep Medicine; Romigi A, D'Aniello A et. al.

Sep 14th, 2020 - Studies looking at the effect of antiseizure medications (ASMs) on the sleep microstructure of subjects with epilepsy are scarce. This study aims to evaluate the impact of eslicarbazepine (ESL) as add-on therapy on the sleep microstructure in temp...

Adipose-Derived Stem Cell transplantation improves learning and memory via releasing ne...
https://doi.org/10.1016/j.brainres.2020.147121
Brain Research; Wang L, Zhao Y et. al.

Sep 13th, 2020 - Epilepsy is a common neurological disease and its most common type is temporal lobe epilepsy (TLE). Novel therapeutics is needed as many TLE patients are resistant to treatments like anticonvulsants or temporal lobectomy. Stem cell therapy has gre...

see more →

Guidelines  23 results

Practice guideline update summary: Efficacy and tolerability of the new antiepileptic d...
https://doi.org/10.1212/WNL.0000000000005756
Neurology Kanner AM, Ashman E et. al.

Jun 14th, 2018 - To update the 2004 American Academy of Neurology guideline for managing treatment-resistant (TR) epilepsy with second- and third-generation antiepileptic drugs (AEDs). 2004 criteria were used to systemically review literature (January 2003 to Nove...

Practice guideline summary: Sudden unexpected death in epilepsy incidence rates and ris...
https://doi.org/10.1212/WNL.0000000000003685
Neurology Harden C, Tomson T et. al.

Apr 25th, 2017 - To determine the incidence rates of sudden unexpected death in epilepsy (SUDEP) in different epilepsy populations and address the question of whether risk factors for SUDEP have been identified. Systematic review of evidence; modified Grading Reco...

Cavernoma-related epilepsy: review and recommendations for management--report of the Su...
https://doi.org/10.1111/epi.12402
Epilepsia Rosenow F, Alonso-Vanegas MA et. al.

Oct 18th, 2013 - Cerebral cavernous malformations (CCMs) are well-defined, mostly singular lesions present in 0.4-0.9% of the population. Epileptic seizures are the most frequent symptom in patients with CCMs and have a great impact on social function and quality ...

Evidence-based guideline update: Vagus nerve stimulation for the treatment of epilepsy: Repo...
https://www.aesnet.org/sites/default/files/file_attach/Guidelines/Neurology-2013-Morris-1453-9.pdf
George L. Morris III

Aug 27th, 2013 - VNS may be considered for seizures in children, for LGS-associated seizures, and for improving mood in adults with epilepsy (Level C). VNS may be considered to have improved efficacy over time (Level C).

Management issues for women with epilepsy-Focus on pregnancy (an evidence-based review)...
https://doi.org/10.1111/j.1528-1167.2009.02129.x
Epilepsia Harden CL, Meador KJ et. al.

Jun 9th, 2009 - A committee assembled by the American Academy of Neurology (AAN) reassessed the evidence related to the care of women with epilepsy (WWE) during pregnancy, including antiepileptic drug (AED) teratogenicity and adverse perinatal outcomes. It is hig...

see more →

Drugs  887 results see all →

Clinicaltrials.gov  12,703 results

The functional connectivity study on the brainstem-cortical/subcortical structures in r...
https://doi.org/10.1002/jdn.10064
International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience; Zhu J, Wang J et. al.

Sep 15th, 2020 - Cervical vagus nerve stimulation (VNS) is an effective neuromodulation therapy for patients with drug-resistant epilepsy (DRE). The previous studies reported that VNS may reduce seizures by regulating the functional connectivity (FC) between corti...

Impaired State-Dependent Potentiation of GABAergic Synaptic Currents Triggers Seizures ...
https://doi.org/10.1093/cercor/bhaa256
Cerebral Cortex (New York, N.Y. : 1991); Zhang CQ, Catron MA et. al.

Sep 15th, 2020 - Epileptic activity in genetic generalized epilepsy (GGE) patients preferentially appears during sleep and its mechanism remains unknown. Here, we found that sleep-like slow-wave oscillations (0.5 Hz SWOs) potentiated excitatory and inhibitory syna...

Etiology-related degree of sprouting of parvalbumin-immunoreactive axons in the human d...
https://doi.org/10.1016/j.neuroscience.2020.09.018
Neuroscience Ábrahám H, Molnár JE et. al.

Sep 15th, 2020 - In the present study, we examined parvalbumin-immunoreactive cells and axons in the dentate gyrus of surgically resected tissues of therapy-resistant temporal lobe epilepsy (TLE) patients with different etiologies. Based on MRI results, five group...

Effects of eslicarbazepine as add-on therapy on sleep architecture in temporal lobe epi...
https://doi.org/10.1016/j.sleep.2020.06.033
Sleep Medicine; Romigi A, D'Aniello A et. al.

Sep 14th, 2020 - Studies looking at the effect of antiseizure medications (ASMs) on the sleep microstructure of subjects with epilepsy are scarce. This study aims to evaluate the impact of eslicarbazepine (ESL) as add-on therapy on the sleep microstructure in temp...

Adipose-Derived Stem Cell transplantation improves learning and memory via releasing ne...
https://doi.org/10.1016/j.brainres.2020.147121
Brain Research; Wang L, Zhao Y et. al.

Sep 13th, 2020 - Epilepsy is a common neurological disease and its most common type is temporal lobe epilepsy (TLE). Novel therapeutics is needed as many TLE patients are resistant to treatments like anticonvulsants or temporal lobectomy. Stem cell therapy has gre...

see more →

News  175 results

Antiepileptic drugs may not independently impair cognition
https://www.mdedge.com/jcomjournal/article/217306/epilepsy-seizures/antiepileptic-drugs-may-not-independently-impair/page/0/1?channel=258

Feb 13th, 2020 - Approximately 45% of patients were prescribed AED polypharmacy on admission, 25. 1% were prescribed AED monotherapy, and 29.

Outcomes of epilepsy surgery at 1 year may be better among older patients
https://www.mdedge.com/familymedicine/article/213808/epilepsy-seizures/outcomes-epilepsy-surgery-1-year-may-be-better-among?channel=39313
Clinical Neurology News; Erik Greb

Dec 8th, 2019 - BALTIMORE – Older patients may have better outcomes at 1 year after resective surgery for epilepsy than the general population does, according to research presented at the annual meeting of the American Epilepsy Society. A tendency toward greater.

Is serum serotonin level associated with risk of seizure-related breathing dysfunction?
https://www.mdedge.com/neurology/article/207435/epilepsy-seizures/serum-serotonin-level-associated-risk-seizure-related?channel=27970
Erik Greb

Sep 4th, 2019 - Significant increases in serum serotonin levels after seizures are associated with lower incidence of seizure-related breathing dysfunction in patients with epilepsy, according to research published online Sept. 4 in Neurology.

Cannabidiol reduces seizures in Dravet syndrome
https://www.mdedge.com/neurology/article/200390/epilepsy-seizures/cannabidiol-reduces-seizures-dravet-syndrome?channel=39313
Erik Greb

May 7th, 2019 - Philadelphia – Adjunctive cannabidiol (CBD) reduces seizure frequency in patients with Dravet syndrome, according to research presented at the annual meeting of the American Academy of Neurology. The two dosages in the study appear to have compara.

Population-level rate of SUDEP may have decreased
https://www.mdedge.com/jcomjournal/article/192550/epilepsy-seizures/population-level-rate-sudep-may-have-decreased
Erik Greb

Jan 11th, 2019 - NEW ORLEANS – The population-level rate of sudden unexpected death in epilepsy (SUDEP) may have decreased over time, according to data described at the annual meeting of the American Epilepsy Society. Whether this decrease resulted from an improve.

see more →

Patient Education  29 results see all →