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About 26,456 results

ALLMedicine™ Epilepsy Center

Research & Reviews  12,039 results

Quantitative analysis of cerebellar lobule morphology and clinical cognitive correlates...
https://doi.org/10.1016/j.yebeh.2020.107553
Epilepsy & Behavior : E&B; Guo Q, Wei Z et. al.

Dec 2nd, 2020 - This study was conducted to explore the cerebellar substructure volumetric alterations in refractory unilateral temporal lobe epilepsy (TLE) patients and the relationship with clinical factors and cognitive scores. A total of 48 unilateral refract...

Hippocampal adult-born granule cells drive network activity in a mouse model of chronic...
https://doi.org/10.1038/s41467-020-19969-2
Nature Communications; Sparks FT, Liao Z et. al.

Dec 2nd, 2020 - Temporal lobe epilepsy (TLE) is characterized by recurrent seizures driven by synchronous neuronal activity. The reorganization of the dentate gyrus (DG) in TLE may create pathological conduction pathways for synchronous discharges in the temporal...

Temporal lobe epilepsy surgery in children and adults: A multicenter study.
https://doi.org/10.1111/epi.16772
Epilepsia REFERENCES; Barba C, Cossu M et. al.

Dec 1st, 2020 - To assess seizure and cognitive outcomes and their predictors in children (<16 years at surgery) and adults undergoing temporal lobe epilepsy (TLE) surgery in eight Italian centers. This is a retrospective multicenter study. We performed a descrip...

In vivo γ-aminobutyric acid increase as a biomarker of the epileptogenic zone: An unbia...
https://doi.org/10.1111/epi.16768
Epilepsia REFERENCES; Hamelin S, Stupar V et. al.

Dec 1st, 2020 - Following surgery, focal seizures relapse in 20% to 50% of cases due to the difficulty of delimiting the epileptogenic zone (EZ) by current imaging or electrophysiological techniques. Here, we evaluate an unbiased metabolomics approach based on ex...

Economic burden of epilepsy in children: A population-based matched cohort study in Can...
https://doi.org/10.1111/epi.16775
Epilepsia REFERENCES; Widjaja E, Guttmann A et. al.

Dec 1st, 2020 - The economic burden of childhood epilepsy to the health care system remains poorly understood. This study aimed to determine phase-specific and cumulative long-term health care costs in children with epilepsy (CWE) from the health care payer persp...

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Guidelines  23 results

Practice guideline update summary: Efficacy and tolerability of the new antiepileptic d...
https://doi.org/10.1212/WNL.0000000000005756
Neurology Kanner AM, Ashman E et. al.

Jun 14th, 2018 - To update the 2004 American Academy of Neurology guideline for managing treatment-resistant (TR) epilepsy with second- and third-generation antiepileptic drugs (AEDs). 2004 criteria were used to systemically review literature (January 2003 to Nove...

Practice guideline summary: Sudden unexpected death in epilepsy incidence rates and ris...
https://doi.org/10.1212/WNL.0000000000003685
Neurology Harden C, Tomson T et. al.

Apr 25th, 2017 - To determine the incidence rates of sudden unexpected death in epilepsy (SUDEP) in different epilepsy populations and address the question of whether risk factors for SUDEP have been identified. Systematic review of evidence; modified Grading Reco...

Cavernoma-related epilepsy: review and recommendations for management--report of the Su...
https://doi.org/10.1111/epi.12402
Epilepsia Rosenow F, Alonso-Vanegas MA et. al.

Oct 18th, 2013 - Cerebral cavernous malformations (CCMs) are well-defined, mostly singular lesions present in 0.4-0.9% of the population. Epileptic seizures are the most frequent symptom in patients with CCMs and have a great impact on social function and quality ...

Evidence-based guideline update: Vagus nerve stimulation for the treatment of epilepsy: Repo...
https://www.aesnet.org/sites/default/files/file_attach/Guidelines/Neurology-2013-Morris-1453-9.pdf
George L. Morris III

Aug 27th, 2013 - VNS may be considered for seizures in children, for LGS-associated seizures, and for improving mood in adults with epilepsy (Level C). VNS may be considered to have improved efficacy over time (Level C).

Management issues for women with epilepsy-Focus on pregnancy (an evidence-based review)...
https://doi.org/10.1111/j.1528-1167.2009.02129.x
Epilepsia Harden CL, Meador KJ et. al.

Jun 9th, 2009 - A committee assembled by the American Academy of Neurology (AAN) reassessed the evidence related to the care of women with epilepsy (WWE) during pregnancy, including antiepileptic drug (AED) teratogenicity and adverse perinatal outcomes. It is hig...

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Drugs  919 results see all →

Clinicaltrials.gov  13,143 results

Quantitative analysis of cerebellar lobule morphology and clinical cognitive correlates...
https://doi.org/10.1016/j.yebeh.2020.107553
Epilepsy & Behavior : E&B; Guo Q, Wei Z et. al.

Dec 2nd, 2020 - This study was conducted to explore the cerebellar substructure volumetric alterations in refractory unilateral temporal lobe epilepsy (TLE) patients and the relationship with clinical factors and cognitive scores. A total of 48 unilateral refract...

Hippocampal adult-born granule cells drive network activity in a mouse model of chronic...
https://doi.org/10.1038/s41467-020-19969-2
Nature Communications; Sparks FT, Liao Z et. al.

Dec 2nd, 2020 - Temporal lobe epilepsy (TLE) is characterized by recurrent seizures driven by synchronous neuronal activity. The reorganization of the dentate gyrus (DG) in TLE may create pathological conduction pathways for synchronous discharges in the temporal...

Temporal lobe epilepsy surgery in children and adults: A multicenter study.
https://doi.org/10.1111/epi.16772
Epilepsia REFERENCES; Barba C, Cossu M et. al.

Dec 1st, 2020 - To assess seizure and cognitive outcomes and their predictors in children (<16 years at surgery) and adults undergoing temporal lobe epilepsy (TLE) surgery in eight Italian centers. This is a retrospective multicenter study. We performed a descrip...

In vivo γ-aminobutyric acid increase as a biomarker of the epileptogenic zone: An unbia...
https://doi.org/10.1111/epi.16768
Epilepsia REFERENCES; Hamelin S, Stupar V et. al.

Dec 1st, 2020 - Following surgery, focal seizures relapse in 20% to 50% of cases due to the difficulty of delimiting the epileptogenic zone (EZ) by current imaging or electrophysiological techniques. Here, we evaluate an unbiased metabolomics approach based on ex...

Economic burden of epilepsy in children: A population-based matched cohort study in Can...
https://doi.org/10.1111/epi.16775
Epilepsia REFERENCES; Widjaja E, Guttmann A et. al.

Dec 1st, 2020 - The economic burden of childhood epilepsy to the health care system remains poorly understood. This study aimed to determine phase-specific and cumulative long-term health care costs in children with epilepsy (CWE) from the health care payer persp...

see more →

News  303 results

Why Are Cases of SUDEP Declining?
https://www.medscape.com/viewarticle/937275

Sep 22nd, 2020 - This transcript has been edited for clarity. Andrew N. Wilner, MD: Welcome to Medscape. I'm Dr Andrew Wilner. Today I have a special guest, Dr Daniel Friedman, professor of neurology at New York University medical school and the author of a paper ...

Why Are Cases of SUDEP Declining?
https://www.staging.medscape.com/viewarticle/937275

Sep 22nd, 2020 - This transcript has been edited for clarity. Andrew N. Wilner, MD: Welcome to Medscape. I'm Dr Andrew Wilner. Today I have a special guest, Dr Daniel Friedman, professor of neurology at New York University medical school and the author of a paper ...

Epilepsy After TBI Linked to Worse 12-Month Outcomes
https://www.medscape.com/viewarticle/933393

Jul 2nd, 2020 - The severity of head injury in traumatic brain injury (TBI) is significantly linked with the risk of developing posttraumatic epilepsy (PTE) and seizures, and PTE itself further worsens outcomes at 12 months, findings from an analysis of a large, ...

FDA Okays New Treatment for Dravet Syndrome
https://www.medscape.com/viewarticle/933039

Jun 25th, 2020 - The US Food and Drug Administration (FDA) has approved fenfluramine (Fintepla, Zogenix) oral solution, a Schedule IV controlled substance, for the treatment of seizures associated with Dravet syndrome in children age 2 years and older. Dravet synd...

Frontal Lobe Glucose Abnormalities May Flag SUDEP Risk
https://www.medscape.com/viewarticle/930596

May 14th, 2020 - Certain patterns of frontal lobe glucose hypometabolism may be associated with higher risk for sudden unexpected death in epilepsy (SUDEP) among patients with refractory focal epilepsy, new research suggests. "The data provide initial evidence tha...

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Patient Education  29 results see all →