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About 2,513 results

ALLMedicine™ Generalized Tonic-clonic Seizures Center

Research & Reviews  429 results

Chronic Ocular Sequelae and Subsequent Surgical Interventions in Stevens-Johnson Syndro...
https://doi.org/10.1097/ICO.0000000000002816
Cornea Sharma S, Singh S et. al.

Jul 24th, 2021 - The purpose of this study was to describe the chronic ocular sequelae and subsequent surgical interventions after amniotic membrane transplantation (AMT) in a patient with Stevens-Johnson syndrome (SJS). A 30-year-old woman was diagnosed with SJS ...

Sudden unexpected death in epilepsy: Experience of neurologists in Saudi Arabia.
https://doi.org/10.1016/j.yebeh.2021.108025
Epilepsy & Behavior : E&B; Hakami T, Hakami M

May 23rd, 2021 - Sudden unexpected death in epilepsy (SUDEP) may account for up to 17% of all deaths in epilepsy. However, it is unknown if neurologists discuss this risk with patients. This study aimed to examine the understanding and practices of SUDEP by neurol...

Unilateral cerebral cortical encephalitis (CCE) with positive anti-MOG antibodies: A ca...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137040
Medicine Nie H, Gao H et. al.

May 21st, 2021 - Nowadays, myelin oligodendrocyte glycoprotein (MOG)-antibody-associated disease (MOGAD) is regarded as an independent inflammatory demyelinating disease. Here, we report a rare case of unilateral cerebral cortical encephalitis (CCE) with positive ...

Development of an antiseizure drug screening platform for Dravet syndrome at the NINDS ...
https://doi.org/10.1111/epi.16925
Epilepsia Pernici CD, Mensah JA et. al.

May 19th, 2021 - Dravet syndrome (DS) is a rare but catastrophic genetic epilepsy, with 80% of patients carrying a mutation in the SCN1A gene. Currently, no antiseizure drug (ASD) exists that adequately controls seizures. In the clinic, individuals with DS often p...

Functional and structural connective disturbance of the primary and default network in ...
https://doi.org/10.1016/j.eplepsyres.2021.106595
Epilepsy Research; Zhang Y, Huang G et. al.

May 17th, 2021 - The present study aims to investigate the disturbance of functional and structural profiles of patients with generalized tonic-clonic seizures (GTCS). Resting-state fMRI and diffusion tensor imaging (DTI) data was collected from fifty-six patients...

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Guidelines  1 results

Practice guideline update summary: Efficacy and tolerability of the new antiepileptic d...
https://doi.org/10.1212/WNL.0000000000005755
Neurology Kanner AM, Ashman E et. al.

Jun 15th, 2018 - To update the 2004 American Academy of Neurology (AAN) guideline for treating new-onset focal or generalized epilepsy with second- and third-generation antiepileptic drugs (AEDs). The 2004 AAN criteria were used to systematically review literature...

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Drugs  503 results see all →

Clinicaltrials.gov  17 results

Study to Evaluate the Efficacy and Safety of Perampanel as Monotherapy or First Adjunctive Therapy in Subjects With Partial Onset Seizures With or Without Secondarily Generalized Seizures or With P...
https://clinicaltrials.gov/ct2/show/NCT03288129

Apr 6th, 2020 - This study will assess the retention rate of perampanel when given as monotherapy or first adjunctive therapy in participants with partial-onset seizures or primary generalized tonic clonic seizures. The study consists of 4 periods: a Screening Pe...

Embrace: Seizure Characterization
https://clinicaltrials.gov/ct2/show/NCT03206502

Jul 18th, 2019 - Patients use the Embrace sensor with a smartphone app, "Alert". The sensor attempts to capture convulsive seizure events such as generalized tonic-clonic seizures (GTCS's), and to initiate an alert when such an event is captured. Patients can also...

A Double-blind, Placebo-controlled Study of Levetiracetam in Epilepsy Patients With Generalized Tonic-clonic Seizures (Except Partial Seizures Evolving to Secondarily Generalized Seizures)
https://clinicaltrials.gov/ct2/show/NCT01228747

Jan 15th, 2019 - The purpose of this study is to evaluate the efficacy, safety and tolerability of levetiracetam treatment used as adjunctive therapy in Japanese and Chinese epilepsy patients aged ≥16 years and with uncontrolled Generalized Tonic-Clonic seizures d...

Trial to Demonstrate the Efficacy and Safety of Conversion to Lacosamide Monotherapy for Partial-onset Seizures
https://clinicaltrials.gov/ct2/show/NCT00520741

Jul 19th, 2018 - Sudden unexplained death in epilepsy have been reported in epilepsy patients. A causal relationship with the administration of antiepileptic drugs has not been established. The most important known risk factor for sudden unexplained death in epile...

Detecting Generalized Tonic-Clonic Seizures With a Seizure Detection and Warning System in Epilepsy Patients
https://clinicaltrials.gov/ct2/show/NCT02371200

Jul 10th, 2018 - This study "A Pivotal, Phase III Trial of Detecting generalized tonic-clonic seizures with a Seizure Detection and Warning System in Epilepsy Patients " is a phase III, pivotal, prospective study of an electromyography (EMG) based seizure detectio...

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News  55 results

Little Evidence to Support Treatments for Prevention of Sudden Unexpected Death in Epilepsy
https://www.medscape.com/viewarticle/928854

Apr 17th, 2020 - NEW YORK (Reuters Health) - More research is needed to identify effective interventions aimed at preventing sudden unexpected death in patients with epilepsy (SUDEP), according to an updated Cochrane review. SUDEP occurs with an incidence of 1 to ...

Levetiracetam Oral Solution Recalled in US
https://www.medscape.com/viewarticle/922974

Dec 20th, 2019 - Lannett Company Inc has voluntarily recalled two lots of levetiracetam oral solution (100 mg/mL) to the consumer level because of contamination with Bacillus subtilis, which was identified during an evaluation of a raw material used to manufacture...

Dr. Reddy's Laboratories Continues its Voluntary Nationwide Recall of Levetiracetam in 0.54% Sodium Chloride Injection 1500mg/100mL Due to Mislabeling | FDA
https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts/dr-reddys-laboratories-continues-its-voluntary-nationwide-recall-levetiracetam-054-sodium-chloride

Summary Company Announcement Date: February 04, 2019 FDA Publish Date: February 04, 2019 Product Type: Drugs Generic Drugs Reason for Announcement: Recall Reason Description Mislabeling Company Name: Dr. Reddy’s Laboratories Ltd. Brand Name: Brand...

FDA Clears Epilepsy Smartwatch for Use in Children
https://www.medscape.com/viewarticle/907432

Jan 9th, 2019 - The US Food and Drug Administration (FDA) has cleared for marketing the Embrace smartwatch (Empatica Inc) for seizure tracking in children as young as age 6. The Embrace smartwatch detects patterns in motion and physiological signals that may be a...

FDA Clears Epilepsy Smartwatch for Use in Children
https://www.staging.medscape.com/viewarticle/907432

Jan 9th, 2019 - The US Food and Drug Administration (FDA) has cleared for marketing the Embrace smartwatch (Empatica Inc) for seizure tracking in children as young as age 6. The Embrace smartwatch detects patterns in motion and physiological signals that may be a...

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