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About 86,912 results

ALLMedicine™ Ischemic Stroke Center

Research & Reviews  41,097 results

Alteplase for Acute Ischemic Stroke Beyond 3 hours: Enthusiasm Outpaces Evidence.
https://doi.org/10.5811/westjem.2021.1.50764
The Western Journal of Emergency Medicine; Garg R

Jun 14th, 2021 - Alteplase for Acute Ischemic Stroke Beyond 3 hours: Enthusiasm Outpaces Evidence.|2021|Garg R,|

Ischemia Injury induces mitochondrial permeability transition pore opening by reducing ...
https://doi.org/10.1016/j.neuroscience.2021.06.003
Neuroscience Yang Y, Tian Y et. al.

Jun 13th, 2021 - Mitochondrial permeability transition pore (mPTP) opening is critical to mitochondrial apoptosis during ischemic injury. Sirtuin 3 (Sirt3) is a mitochondrial deacetylase known to play a major role in stress resistance and cell death. Our previous ...

Novel peripheral blood cell ratios: Effective 3-month post-mechanical thrombectomy prog...
https://doi.org/10.1016/j.jocn.2021.04.013
Journal of Clinical Neuroscience : Official Journal of Th... Li X, Wu F et. al.

Jun 13th, 2021 - Red blood cell distribution width to platelet ratio (RPR), Monocyte to high-density lipoprotein ratio (MHR), and Neutrophil to lymphocyte ratio (NLR) are novel inflammatory biomarkers in laboratory tests, which are associated with clinical outcome...

Immune-inflammatory, coagulation, adhesion, and imaging biomarkers combined in machine ...
https://doi.org/10.1007/s10238-021-00732-w 10.1016/S1474-4422(19)30034-1 10.1016/j.jemermed.2005.10.003 10.1038/s41582-020-0350-6 10.1159/000196823 10.1016/j.nut.2012.12.015 10.1097/MD.0000000000010412 10.1007/s11011-019-00403-6 10.1371/journal.pmed.1000145 10.1161/01.str.20.7.864 10.1161/01.str.19.12.1497 10.1212/wnl.53.1.126 10.1161/hs0202.102881 10.1161/01.STR.0000106761.94985.8B 10.1007/s13311-016-0470-2 10.1310/tsr2006-528 10.1161/CIRCULATIONAHA.106.628875 10.1038/hr.2013.61 10.1590/1516-3180.2017.0272141017 10.1177/0003319717716842 10.1161/01.cir.96.5.1432 10.1161/STROKEAHA.110.592261 10.1161/01.STR.0000226399.13528.0a 10.1016/j.clineuro.2008.10.007 10.1111/j.1747-4949.2009.00387.x 10.1161/STROKEAHA.114.006394 10.1161/ATVBAHA.118.312102 10.1016/S1474-4422(16)00114-9 10.1080/00207454.2017.1408614 10.1161/01.str.31.10.2325 10.1186/1471-2377-4-2 10.1111/j.1468-1331.2006.01280.x 10.1038/nm.1927 10.1212/01.wnl.0000247064.53130.91 10.1186/1471-2377-13-7 10.1161/01.str.32.4.917 10.1007/s00415-009-5228-x 10.1111/j.1755-5949.2012.00296.x 10.1016/j.jocn.2013.06.015 10.1016/j.jns.2015.03.032 10.3390/ijerph13070636 10.1371/journal.pone.0156790 10.1161/01.STR.0000165929.78756.ed 10.3390/bios7030030 10.1159/000356789 10.1161/CIRCULATIONAHA.106.635029 10.1136/svn-2018-000169 10.1186/s41983-018-0019-x 10.1097/00001721-199907000-00009 10.1093/jnen/62.2.127 10.1093/brain/awr008 10.3390/diagnostics10100804 10.1080/10408363.2018.1461190 10.1161/01.str.24.1.35 10.1161/01.str.31.5.1062 10.1001/jama.2013.284427 10.2337/diaclin.34.1.3 10.1161/circ.106.25.3143 10.1016/j.atherosclerosis.2015.05.007 10.1159/000081812 10.1016/j.jstrokecerebrovasdis.2012.10.013 10.1016/j.jstrokecerebrovasdis.2016.11.016 10.1177/1756286418789340 10.1152/ajpcell.00136.2018 10.14336/AD.2018.0820 10.1038/nn.3599 10.1002/glia.22675 10.1186/1471-2377-13-62 10.1007/s12031-015-0705-4 10.1016/0003-9861(90)90510-6 10.1002/hep.20720 10.1080/00207454.2018.1538139 10.1080/09537104.2019.1680826 10.1161/01.STR.22.1.17 10.3109/00207454.2010.523134 10.1371/journal.pone.0089756 10.1161/STROKEAHA.111.634089 10.1159/000100404 10.1034/j.1600-0404.2002.1o112.x 10.1016/j.ijcard.2007.11.031
Clinical and Experimental Medicine; Lehmann ALCF, Alfieri DF et. al.

Jun 13th, 2021 - Some clinical, imaging, and laboratory biomarkers have been identified as predictors of prognosis of acute ischemic stroke (IS). The aim of this study was to evaluate the prognostic validity of a combination of clinical, imaging, and laboratory bi...

miR-1224 contributes to ischemic stroke-mediated natural killer cell dysfunction by tar...
https://doi.org/10.1186/s12974-021-02181-4 10.1038/s41572-019-0118-8 10.1016/j.immuni.2017.03.001 10.1016/j.immuni.2017.02.015 10.1016/S0092-8674(04)00045-5 10.1089/rej.2018.2126 10.1002/jcp.25787 10.1038/jcbfm.2009.186 10.1111/cns.12019 10.1007/s12975-010-0030-8 10.1155/2018/2835761 10.4049/jimmunol.1000980 10.4049/jimmunol.1102294 10.1182/blood-2011-11-394072 10.1038/nrg1379 10.1126/science.1149460 10.1038/nrm1644 10.1002/eji.201444798 10.1016/j.biopha.2018.09.172 10.1038/cmi.2015.113 10.1182/blood-2014-08-593343 10.1038/ni1527 10.1186/s12974-017-1017-0 10.1177/0271678X15611137 10.14336/AD.2019.0608 10.1172/JCI95612 10.1038/75556 10.1093/nar/gkw1092 10.1002/glia.23530 10.1016/j.jhep.2017.06.007 10.1111/j.1365-2567.2010.03374.x 10.1084/jem.20021098 10.1016/j.tube.2017.05.002 10.1016/S0140-6736(15)00126-9 10.1073/pnas.1315943111 10.1182/blood-2011-04-347526 10.4049/jimmunol.1200609 10.1016/j.jaci.2014.02.018 10.1038/srep09993 10.1161/01.STR.0000258346.68966.9d 10.1161/STROKEAHA.109.557967 10.1161/STROKEAHA.109.549618 10.1096/fj.201700324r 10.1038/s41388-020-01493-8 10.3389/fimmu.2020.00759
Journal of Neuroinflammation; Feng Y, Li Y et. al.

Jun 13th, 2021 - Brain ischemia compromises natural killer (NK) cell-mediated immune defenses by acting on neurogenic and intracellular pathways. Less is known about the posttranscriptional mechanisms that regulate NK cell activation and cytotoxicity after ischemi...

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Guidelines  121 results

Draft Recommendation Statement: Screening for Atrial Fibrillation
https://www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/screening-atrial-fibrillation
US Preventative Services Task Force (USPSTF)

Apr 18th, 2021 - AF is the most common arrhythmia. The prevalence of AF increases with age, from less than 0.2% in adults younger than age 55 years to about 10% in those age 85 years or older, with a higher prevalence in men than in women.1 AF is a major risk fact...

Screening for Asymptomatic Carotid Artery Stenosis: US Preventive Services Task Force R...
https://doi.org/10.1001/jama.2020.26988
JAMA , Krist AH et. al.

Feb 2nd, 2021 - Carotid artery stenosis is atherosclerotic disease that affects extracranial carotid arteries. Asymptomatic carotid artery stenosis refers to stenosis in persons without a history of ischemic stroke, transient ischemic attack, or other neurologic ...

Screening for Asymptomatic Carotid Artery Stenosis
https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/carotid-artery-stenosis-screening
US Preventative Services Task Force (USPSTF)

Feb 1st, 2021 - Carotid artery stenosis is atherosclerotic disease that affects extracranial carotid arteries. Asymptomatic carotid artery stenosis refers to stenosis in persons without a history of ischemic stroke, transient ischemic attack, or other neurologic ...

Practice recommendations for neurovascular ultrasound investigations of acute stroke pa...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276863
European Journal of Neurology References; Baracchini C, Pieroni A et. al.

May 19th, 2020 - Patients with acute ischemic stroke are at high-risk for contracting COVID-19 infection. Additionally, healthcare professionals including neurovascular ultrasound providers are also at risk of being infected by SARS-CoV-2 virus. Yet, preparedness ...

Anesthetic Management of Endovascular Treatment of Acute Ischemic Stroke During COVID-1...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236841
Journal of Neurosurgical Anesthesiology; Sharma D, Rasmussen M et. al.

Apr 13th, 2020 - The pandemic of coronavirus disease 2019 (COVID-19) has unique implications for the anesthetic management of endovascular therapy for acute ischemic stroke. The Society for Neuroscience in Anesthesiology and Critical Care appointed a task force to...

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Drugs  57 results see all →

Clinicaltrials.gov  43,017 results

Stroke Risk in New-Onset Atrial Fib Goes Up With Greater Alcohol Intake
https://www.medscape.com/viewarticle/953317

Jun 16th, 2021 - There's abundant evidence linking higher alcohol intake levels to greater stroke risk and, separately, increasing risk for new-onset atrial fibrillation (AF). Less settled is whether moderate to heavy drinking worsens the risk for stroke in patien...

Alteplase for Acute Ischemic Stroke Beyond 3 hours: Enthusiasm Outpaces Evidence.
https://doi.org/10.5811/westjem.2021.1.50764
The Western Journal of Emergency Medicine; Garg R

Jun 14th, 2021 - Alteplase for Acute Ischemic Stroke Beyond 3 hours: Enthusiasm Outpaces Evidence.|2021|Garg R,|

Ischemia Injury induces mitochondrial permeability transition pore opening by reducing ...
https://doi.org/10.1016/j.neuroscience.2021.06.003
Neuroscience Yang Y, Tian Y et. al.

Jun 13th, 2021 - Mitochondrial permeability transition pore (mPTP) opening is critical to mitochondrial apoptosis during ischemic injury. Sirtuin 3 (Sirt3) is a mitochondrial deacetylase known to play a major role in stress resistance and cell death. Our previous ...

Novel peripheral blood cell ratios: Effective 3-month post-mechanical thrombectomy prog...
https://doi.org/10.1016/j.jocn.2021.04.013
Journal of Clinical Neuroscience : Official Journal of Th... Li X, Wu F et. al.

Jun 13th, 2021 - Red blood cell distribution width to platelet ratio (RPR), Monocyte to high-density lipoprotein ratio (MHR), and Neutrophil to lymphocyte ratio (NLR) are novel inflammatory biomarkers in laboratory tests, which are associated with clinical outcome...

Immune-inflammatory, coagulation, adhesion, and imaging biomarkers combined in machine ...
https://doi.org/10.1007/s10238-021-00732-w 10.1016/S1474-4422(19)30034-1 10.1016/j.jemermed.2005.10.003 10.1038/s41582-020-0350-6 10.1159/000196823 10.1016/j.nut.2012.12.015 10.1097/MD.0000000000010412 10.1007/s11011-019-00403-6 10.1371/journal.pmed.1000145 10.1161/01.str.20.7.864 10.1161/01.str.19.12.1497 10.1212/wnl.53.1.126 10.1161/hs0202.102881 10.1161/01.STR.0000106761.94985.8B 10.1007/s13311-016-0470-2 10.1310/tsr2006-528 10.1161/CIRCULATIONAHA.106.628875 10.1038/hr.2013.61 10.1590/1516-3180.2017.0272141017 10.1177/0003319717716842 10.1161/01.cir.96.5.1432 10.1161/STROKEAHA.110.592261 10.1161/01.STR.0000226399.13528.0a 10.1016/j.clineuro.2008.10.007 10.1111/j.1747-4949.2009.00387.x 10.1161/STROKEAHA.114.006394 10.1161/ATVBAHA.118.312102 10.1016/S1474-4422(16)00114-9 10.1080/00207454.2017.1408614 10.1161/01.str.31.10.2325 10.1186/1471-2377-4-2 10.1111/j.1468-1331.2006.01280.x 10.1038/nm.1927 10.1212/01.wnl.0000247064.53130.91 10.1186/1471-2377-13-7 10.1161/01.str.32.4.917 10.1007/s00415-009-5228-x 10.1111/j.1755-5949.2012.00296.x 10.1016/j.jocn.2013.06.015 10.1016/j.jns.2015.03.032 10.3390/ijerph13070636 10.1371/journal.pone.0156790 10.1161/01.STR.0000165929.78756.ed 10.3390/bios7030030 10.1159/000356789 10.1161/CIRCULATIONAHA.106.635029 10.1136/svn-2018-000169 10.1186/s41983-018-0019-x 10.1097/00001721-199907000-00009 10.1093/jnen/62.2.127 10.1093/brain/awr008 10.3390/diagnostics10100804 10.1080/10408363.2018.1461190 10.1161/01.str.24.1.35 10.1161/01.str.31.5.1062 10.1001/jama.2013.284427 10.2337/diaclin.34.1.3 10.1161/circ.106.25.3143 10.1016/j.atherosclerosis.2015.05.007 10.1159/000081812 10.1016/j.jstrokecerebrovasdis.2012.10.013 10.1016/j.jstrokecerebrovasdis.2016.11.016 10.1177/1756286418789340 10.1152/ajpcell.00136.2018 10.14336/AD.2018.0820 10.1038/nn.3599 10.1002/glia.22675 10.1186/1471-2377-13-62 10.1007/s12031-015-0705-4 10.1016/0003-9861(90)90510-6 10.1002/hep.20720 10.1080/00207454.2018.1538139 10.1080/09537104.2019.1680826 10.1161/01.STR.22.1.17 10.3109/00207454.2010.523134 10.1371/journal.pone.0089756 10.1161/STROKEAHA.111.634089 10.1159/000100404 10.1034/j.1600-0404.2002.1o112.x 10.1016/j.ijcard.2007.11.031
Clinical and Experimental Medicine; Lehmann ALCF, Alfieri DF et. al.

Jun 13th, 2021 - Some clinical, imaging, and laboratory biomarkers have been identified as predictors of prognosis of acute ischemic stroke (IS). The aim of this study was to evaluate the prognostic validity of a combination of clinical, imaging, and laboratory bi...

see more →

News  2,609 results

Stroke Risk in New-Onset Atrial Fib Goes Up With Greater Alcohol Intake
https://www.medscape.com/viewarticle/953317

Jun 16th, 2021 - There's abundant evidence linking higher alcohol intake levels to greater stroke risk and, separately, increasing risk for new-onset atrial fibrillation (AF). Less settled is whether moderate to heavy drinking worsens the risk for stroke in patien...

Extended AF Monitoring Worth Considering After Eye Stroke
https://www.medscape.com/viewarticle/953084

Jun 13th, 2021 - Extended cardiac monitoring for the detection of atrial fibrillation (AF) should be considered in patients who have a stroke caused by central retinal artery occlusion, a new study suggests. The study showed a high rate of device-detected AF in pa...

Evidence Mounts for Implantable AF Monitoring After Stroke
https://www.medscape.com/viewarticle/952325

Jun 1st, 2021 - Two new randomized trials have added to the evidence that rates of atrial fibrillation (AF) detection are increased through the use of long-term monitoring with implantable devices. The studies have also expanded the population that may be targete...

Eight Things to Know About the Surgical Left Atrial Appendage Occlusion (LAAOS III) Trial
https://www.medscape.com/viewarticle/951229

May 14th, 2021 - In the Left Atrial Appendage Occlusion (LAAOS III) trial, slightly more than 4800 patients with atrial fibrillation (AF) scheduled for open-heart surgery were randomly assigned to add-on surgical closure of the left atrial appendage or heart surge...

Watchman Registry: 1-Year Stroke Estimates Reassuringly Low
https://www.medscape.com/viewarticle/951235

May 14th, 2021 - The Watchman left atrial appendage (LAA) closure device (Boston Scientific) is associated with low 1-year stroke rates, despite being used commercially in older, sicker patients than seen in pivotal clinical trials, new data suggest. Among more th...

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Patient Education  11 results see all →