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About 7,530 results

ALLMedicine™ Status Epilepticus Center

Research & Reviews  2,714 results

Improving time for administration of second-line antiseizure medications for children w...
https://doi.org/10.1111/epi.17026
Epilepsia Vidaurre J, Albert DVF et. al.

Jul 31st, 2021 - Status epilepticus is a life-threatening neurological emergency. However, delay in median time to administration of second-line antiseizure medication exists. The aim of this quality improvement initiative was to decrease the average delay before ...

Predictive factors of Status Epilepticus and its recurrence in patients with adult-onse...
https://doi.org/10.1016/j.seizure.2021.07.009
Seizure Gasparini S, Ferlazzo E et. al.

Jul 24th, 2021 - Status epilepticus (SE) is associated with high morbidity and mortality. This multicenter retrospective cohort study aims to identify the factors associated with the occurrence of SE and the predictors of its recurrence in patients with adult-onse...

Seizure-mediated iron accumulation and dysregulated iron metabolism after status epilep...
https://doi.org/10.1007/s00401-021-02348-6 10.1002/jmri.25777 10.1111/bpa.12661 10.1016/j.neuroscience.2007.10.036 10.1111/epi.12220 10.1111/epi.14550 10.1371/journal.pone.0185056 10.1155/2014/759293 10.1016/j.neuroimage.2020.117611 10.1016/j.neuron.2006.07.011 10.3389/fncel.2014.00155 10.1016/s0925-4439(97)00009-4 10.1093/nar/gkt1102 10.1038/sj.emboj.7601409 10.1038/sj.emboj.7601735 10.1007/s00234-017-1813-3 10.1016/j.cell.2012.03.042 10.1089/ars.2010.3412 10.1111/epi.12550 10.1111/j.0013-9580.2005.66104.x 10.1111/j.1528-1167.2011.03227.x 10.1007/s11064-007-9313-1 10.1136/svn-2016-000042 10.1111/j.1528-1167.2005.11505.x 10.1523/JNEUROSCI.2766-06.2006 10.1046/j.1460-9568.2001.01428.x 10.1016/S0021-9258(18)83758-9 10.1039/c0an00269k 10.1101/gr.135350.111 10.1046/j.0953-816x.2001.01778.x 10.1016/j.cell.2010.06.028 10.1074/jbc.M500526200 10.1016/j.cell.2017.11.048 10.1016/j.nbd.2013.03.006 10.1523/JNEUROSCI.2922-06.2006 10.1002/jnr.23328 10.1136/jnnp.61.5.506 10.1038/cddis.2014.390 10.18632/oncotarget.5162 10.1016/j.neuroimage.2012.05.049 10.3389/fphar.2019.00638 10.1186/1742-2094-10-130 10.3389/fnins.2019.00721 10.1038/nm.2127 10.1016/j.celrep.2020.01.010 10.1002/ana.23940 10.1371/journal.pone.0089003 10.1679/aohc.70.1 10.1679/aohc.71.205 10.1126/science.1104742 10.1007/978-3-7091-1434-6_14 10.3791/57548 10.1016/j.nbd.2010.05.003 10.1038/jcbfm.2012.13 10.1016/0731-7085(91)80233-y 10.1074/jbc.272.32.20185 10.1016/j.freeradbiomed.2004.08.021 10.1038/nmeth.4197 10.1093/brain/awz130 10.1111/j.1474-9726.2010.00652.x 10.1016/j.bbadis.2013.04.007 10.1101/cshperspect.a022822 10.1007/s00401-017-1696-8 10.1002/glia.22303 10.1186/s12868-019-0507-7 10.1146/annurev-biochem-060815-014431 10.1016/j.yebeh.2020.106935 10.1093/nar/gkv007 10.1093/bioinformatics/btp616 10.1016/j.freeradbiomed.2013.02.002 10.1093/brain/awy242 10.1016/j.nbd.2018.06.017 10.1016/j.pneurobio.2018.06.008 10.1007/s10534-010-9359-4 10.1093/brain/awy071 10.1016/j.yebeh.2019.07.011 10.1016/j.redox.2019.101278 10.1016/j.freeradbiomed.2015.03.031 10.12688/f1000research.7563.2 10.1002/jcp.20509 10.1016/j.cell.2017.09.021 10.1016/j.neuropharm.2019.107742 10.1007/978-981-13-9589-5_1 10.1002/glia.22983 10.1016/j.semcdb.2014.10.003 10.1093/brain/awl318 10.1016/s0022-510x(02)00435-5 10.1023/a:1014464514793 10.1186/s13041-016-0220-8 10.1002/ana.410040408 10.1096/fj.09-143974 10.1016/j.brainres.2003.10.066 10.1038/sj.emboj.7600540 10.3233/JAD-171108 10.1007/s00424-009-0772-x 10.1016/j.neuron.2015.11.013 10.1111/nan.12596
Acta Neuropathologica; Zimmer TS, David B et. al.

Jul 23rd, 2021 - Neuronal dysfunction due to iron accumulation in conjunction with reactive oxygen species (ROS) could represent an important, yet underappreciated, component of the epileptogenic process. However, to date, alterations in iron metabolism in the epi...

Chronic limbic epilepsy models for therapy discovery: Protocols to improve efficiency.
https://doi.org/10.1111/epi.16995
Epilepsia Bertram EH, Edelbroek P

Jul 22nd, 2021 - There have been recommendations to improve therapy discovery for epilepsy by incorporating chronic epilepsy models into the preclinical process, but unpredictable seizures and difficulties in maintaining drug levels over prolonged periods have bee...

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Guidelines  4 results

ACR Appropriateness Criteria® Seizures-Child.
https://doi.org/10.1016/j.jacr.2021.02.020
Journal of the American College of Radiology : JACR; , Trofimova A et. al.

May 8th, 2021 - In children, seizures represent an extremely heterogeneous group of medical conditions ranging from benign cases, such as a simple febrile seizure, to life-threatening situations, such as status epilepticus. Underlying causes of seizures also repr...

Consensus statement on continuous EEG in critically ill adults and children, part I: in...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435533
Journal of Clinical Neurophysiology : Official Publicatio... Herman ST, Abend NS et. al.

Jan 30th, 2015 - Critical Care Continuous EEG (CCEEG) is a common procedure to monitor brain function in patients with altered mental status in intensive care units. There is significant variability in patient populations undergoing CCEEG and in technical specific...

EFNS guideline on the management of status epilepticus in adults.
https://doi.org/10.1111/j.1468-1331.2009.02917.x
European Journal of Neurology; Meierkord H, Boon P et. al.

Jan 7th, 2010 - The objective of the current article was to review the literature and discuss the degree of evidence for various treatment strategies for status epilepticus (SE) in adults. We searched MEDLINE and EMBASE for relevant literature from 1966 to Januar...

Practice parameter update: management issues for women with epilepsy--focus on pregnanc...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475195
Neurology Harden CL, Hopp J et. al.

Apr 29th, 2009 - To reassess the evidence for management issues related to the care of women with epilepsy (WWE) during pregnancy, including the risk of pregnancy complications or other medical problems during pregnancy in WWE compared to other women, change in se...

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Drugs  85 results see all →

Clinicaltrials.gov  33 results

Study of Midazolam Hydrochloride Oromucosal Solution (MHOS/SHP615) in Pediatric Patients With Status Epilepticus (Convulsive) in the Community Setting
https://clinicaltrials.gov/ct2/show/NCT03336450

Feb 19th, 2020 - The purpose of this study is to determine if the investigational treatment, MHOS/SHP615, is safe and effective in children with status epilepticus (SE) (convulsive) in the community setting. This study is open-label extension for patients who comp...

Open-label Study of Midazolam Hydrochloride Oromucosal Solution (MHOS/SHP615) in Children With Status Epilepticus (Convulsive) in a Healthcare Setting in Japan
https://clinicaltrials.gov/ct2/show/NCT03336645

Feb 18th, 2020 - The purpose of this study is to assess the efficacy, safety and pharmacokinetics of MHOS/SHP615 administered buccally in children with status epilepticus (convulsive) in a healthcare setting.

Intravenous Ganaxolone as Adjunctive Therapy to Treat Subjects With Status Epilepticus
https://clinicaltrials.gov/ct2/show/NCT03350035

Dec 24th, 2019 - This is a double-blind, randomized, placebo-controlled study to evaluate the safety, tolerability, and efficacy of adjunctive IV ganaxolone in subjects with SE. Study drug will be added to standard of care before IV anesthetic during the treatment...

Prompt Diagnosis and Treatment of Subclinical Seizures After Cardiac Arrest
https://clinicaltrials.gov/ct2/show/NCT02458820

Jul 9th, 2019 - Acute symptomatic electroencephalographic (EEG) seizures are common in children who experience a cardiac arrest, and are associated with worse short term survival. In larger studies of critically ill children with heterogeneous acute encephalopath...

A Study With SAGE-547 for Super-Refractory Status Epilepticus
https://clinicaltrials.gov/ct2/show/NCT02477618

May 2nd, 2019 - This is a randomized, double-blind, placebo-controlled trial, designed to evaluate the efficacy and safety of SAGE-547 administered as a continuous intravenous infusion to subjects in Super-Refractory Status Epilepticus (SRSE).

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News  172 results

Why Are Cases of SUDEP Declining?
https://www.medscape.com/viewarticle/937275

Sep 23rd, 2020 - This transcript has been edited for clarity. Andrew N. Wilner, MD: Welcome to Medscape. I'm Dr Andrew Wilner. Today I have a special guest, Dr Daniel Friedman, professor of neurology at New York University medical school and the author of a paper ...

Why Are Cases of SUDEP Declining?
https://www.staging.medscape.com/viewarticle/937275

Sep 23rd, 2020 - This transcript has been edited for clarity. Andrew N. Wilner, MD: Welcome to Medscape. I'm Dr Andrew Wilner. Today I have a special guest, Dr Daniel Friedman, professor of neurology at New York University medical school and the author of a paper ...

Ketamine to the Rescue in Status Epilepticus?
https://www.medscape.com/viewarticle/931936

Jun 17th, 2020 - This transcript has been edited for clarity. Robert D. Glatter, MD: Hello and welcome. I'm Dr Robert Glatter, advisor and editorial board member for Medscape Emergency Medicine. Managing patients with refractory status epilepticus can be quite cha...

Ketamine to the Rescue in Status Epilepticus?
https://www.staging.medscape.com/viewarticle/931936

Jun 17th, 2020 - This transcript has been edited for clarity. Robert D. Glatter, MD: Hello and welcome. I'm Dr Robert Glatter, advisor and editorial board member for Medscape Emergency Medicine. Managing patients with refractory status epilepticus can be quite cha...

Taro Pharmaceuticals U.S.A. Issues Voluntary Nationwide Recall of Phenytoin Oral Suspension Usp, 125 Mg/5 Ml due to Possible Underdosing or Overdosing | FDA
https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts/taro-pharmaceuticals-usa-issues-voluntary-nationwide-recall-phenytoin-oral-suspension-usp-125-mg5-ml

Summary Company Announcement Date: February 20, 2020 FDA Publish Date: February 21, 2020 Product Type: Drugs Reason for Announcement: Recall Reason Description Possible underdosing or overdosing Company Name: Taro Pharmaceuticals U.S.A., Inc. Bran...

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Patient Education  4 results see all →