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About 6,025 results

ALLMedicine™ Temporal Lobe Epilepsy Center

Research & Reviews  2,313 results

Two-trajectory laser amygdalohippocampotomy: Anatomic modeling and initial seizure outc...
https://doi.org/10.1111/epi.17019
Epilepsia Liu DD, Lauro PM et. al.

Aug 3rd, 2021 - Laser interstitial thermal therapy (LITT) for mesial temporal lobe epilepsy (mTLE) is typically performed with one trajectory to target the medial temporal lobe (MTL). MTL structures such as piriform and entorhinal cortex are epileptogenic, but du...

Ultra-High Field 7-Tesla Magnetic Resonance Imaging and Electroencephalography Findings...
https://doi.org/10.1177/08465371211031802
Canadian Association of Radiologists Journal = Journal L'... Salehi F, Nadeem IM et. al.

Jul 31st, 2021 - Assessment of patients for temporal lobe epilepsy (TLE) surgery requires multimodality input, including EEG recordings to ensure optimal surgical planning. Often EEG demonstrates abnormal foci not detected on 1.5T MRI. Ultra-high field MRI at 7T p...

Intraoperative overlay of optic radiation tractography during anteromesial temporal res...
https://doi.org/10.3171/2020.12.JNS203437
Journal of Neurosurgery; Vakharia VN, Vos SB et. al.

Jul 31st, 2021 - Anteromesial temporal lobe resection (ATLR) results in long-term seizure freedom in patients with drug-resistant focal mesial temporal lobe epilepsy (MTLE). There is significant anatomical variation in the anterior projection of the optic radiatio...

Dynamic tractography-based localization of spike sources and animation of spike propaga...
https://doi.org/10.1111/epi.17025
Epilepsia Mitsuhashi T, Sonoda M et. al.

Jul 30th, 2021 - This study was undertaken to build and validate a novel dynamic tractography-based model for localizing interictal spike sources and visualizing monosynaptic spike propagations through the white matter. This cross-sectional study investigated 1900...

Psychiatric outcome of temporal lobe epilepsy surgery: A prospective, 2-year follow-up ...
https://doi.org/10.1016/j.yebeh.2021.108216
Epilepsy & Behavior : E&B; Nishida T, Usui N et. al.

Jul 30th, 2021 - We performed a prospective, longitudinal, 2-year follow-up study to clarify psychiatric courses and outcomes after temporal lobe epilepsy surgery. We assessed 141 patients (68 men, 73 women) aged 16 or older with structured interviews and psychiat...

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Drugs  3 results see all →

Clinicaltrials.gov  20 results

Relationship of HHV-6B Virus to Seizures and Brain Injury
https://clinicaltrials.gov/ct2/show/NCT00597285

Dec 16th, 2019 - Objectives: 1) to attempt to detect specific patterns of hippocampal injury in patients with temporal lobe epilepsy that may be associated with HHV-6B infection; 2) To attempt to detect evidence for persistent HHV6 infection in CSF in patients wit...

Focused Ultrasound Neuromodulation for Treatment of Temporal Lobe Epilepsy
https://clinicaltrials.gov/ct2/show/NCT03657056

Aug 15th, 2019 - Non-invasive and controllable suppression of regional brain activity may open new avenues for the treatment and management of epilepsy. There is good evidence that direct stimulation of epileptogenic sources can powerfully suppress seizure rates, ...

Study of [11C]DPA-713 for Temporal Lobe Epilepsy
https://clinicaltrials.gov/ct2/show/NCT01793532

Nov 5th, 2018 - Background: - Some people with epilepsy have an epileptic focus, a small part of the brain that is the starting point of the seizure. This focus is like an irritant or an inflammation, and helps cause the seizure. People with epilepsy that affects...

Stereotactic Laser Ablation for Temporal Lobe Epilepsy
https://clinicaltrials.gov/ct2/show/NCT02844465

Oct 29th, 2018 - The purpose of the study is to evaluate the safety and efficacy of the Visualase MRI-guided laser ablation system for necrotization or coagulation of epileptogenic foci in patients with intractable mesial temporal lobe epilepsy. The study will inc...

COMETE Study : COgnitive Rehabilitation of MEmory in Temporal Epilepsy
https://clinicaltrials.gov/ct2/show/NCT02589470

Oct 2nd, 2018 - Epilepsy is a chronic neurological disease among the most frequent ones. It causes cognitive disorders in 20 to 50 percent of patients with structural epilepsy, that is to say in connexion with an identified or presumed cerebral lesion. Compared t...

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News  74 results

Should a normal-appearing hippocampus be resected in a patient with temporal lobe epilepsy?
https://www.mdedge.com/neurology/epilepsyresourcecenter/article/215839/epilepsy-seizures/should-normal-appearing?channel=53
Erik Greb

Jan 21st, 2020 - BALTIMORE – Sparing, rather than resecting, a normal-appearing hippocampus in a patient with temporal lobe epilepsy is correlated with an increased risk of early seizure recurrence, according to an analysis presented at the annual meeting of the A.

Scalp EEG predicts temporal lobe resection success
https://www.mdedge.com/neurology/epilepsyresourcecenter/article/213858/epilepsy-seizures/scalp-eeg-predicts-temporal-lobe?channel=53
M. Alexander Otto

Dec 9th, 2019 - BALTIMORE – In a review of 43 temporal lobe epilepsy patients at Yale University in New Haven, Conn. , anteromedial temporal resection (AMTR) failed in every case in which initial ictal rhythm on scalp EEG spread beyond the medial temporal lobe to.

Outcomes of epilepsy surgery at 1 year may be better among older patients
https://www.mdedge.com/familymedicine/article/213808/epilepsy-seizures/outcomes-epilepsy-surgery-1-year-may-be-better-among?channel=39313
Clinical Neurology News; Erik Greb

Dec 8th, 2019 - BALTIMORE – Older patients may have better outcomes at 1 year after resective surgery for epilepsy than the general population does, according to research presented at the annual meeting of the American Epilepsy Society. A tendency toward greater.

Antiepileptic drug outcomes have remained flat for 3 decades
https://www.mdedge.com/jcomjournal/article/205888/epilepsy-seizures/antiepileptic-drug-outcomes-have-remained-flat-3/page/0/1?channel=39313

Aug 5th, 2019 - Roughly similar outcomes have been reported from Norway in a study of 600 children with epilepsy, median age 7 years, with a median follow-up of 5. 8 years that is considerably shorter than that in the Glasgow pediatric study.

Seizure Freedom in TLE Tied to Piriform Cortex Resection
https://www.medscape.com/viewarticle/910752

Mar 21st, 2019 - Removal of at least half of the piriform cortex is required to achieve freedom from seizures in the neurosurgical treatment of temporal lobe epilepsy (TLE), new research suggests. A proof-of-concept study conducted by investigators at University C...

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