ALLMedicine Temporal Lobe Epilepsy Center

May 26th, 2020 - The purpose of this study was to systematically investigate language comprehension in individuals with left and right temporal lobe epilepsy (TLE) at different language levels - single word (noun and verb), sentence, and discourse. Neither of the ...

May 25th, 2020 - Temporal lobe epilepsy (TLE) is the most common drug-resistant epilepsy in adults. Although it is commonly related to hippocampal pathology, increasing evidence suggests structural changes beyond the mesiotemporal lobe. Functional anomalies and th...

May 25th, 2020 - The transition of neuronal burst firing from the interictal to ictal state contributes to seizure initiation in human temporal lobe epilepsy. The low-Mg2+ model of seizure is characterized by initial spontaneous interictal bursting events, which l...

May 24th, 2020 - It is crucial to reveal the variability between patients with epilepsy and healthy subjects to elucidate the underpinnings of the disease pathology. Herein, we assessed the inter-subject variability between patients with temporal lobe epilepsy (TL...

May 24th, 2020 - Perampanel (PER) is a novel antiepileptic drug approved as an add-on therapy for focal onset seizures with or without generalization and primary generalized tonic-clonic seizures. Aim of this study was to evaluate PER efficacy and tolerability as ...

May 26th, 2020 - The purpose of this study was to systematically investigate language comprehension in individuals with left and right temporal lobe epilepsy (TLE) at different language levels - single word (noun and verb), sentence, and discourse. Neither of the ...

May 25th, 2020 - Temporal lobe epilepsy (TLE) is the most common drug-resistant epilepsy in adults. Although it is commonly related to hippocampal pathology, increasing evidence suggests structural changes beyond the mesiotemporal lobe. Functional anomalies and th...

May 25th, 2020 - The transition of neuronal burst firing from the interictal to ictal state contributes to seizure initiation in human temporal lobe epilepsy. The low-Mg2+ model of seizure is characterized by initial spontaneous interictal bursting events, which l...

May 24th, 2020 - It is crucial to reveal the variability between patients with epilepsy and healthy subjects to elucidate the underpinnings of the disease pathology. Herein, we assessed the inter-subject variability between patients with temporal lobe epilepsy (TL...

May 24th, 2020 - Perampanel (PER) is a novel antiepileptic drug approved as an add-on therapy for focal onset seizures with or without generalization and primary generalized tonic-clonic seizures. Aim of this study was to evaluate PER efficacy and tolerability as ...

Jan 21st, 2020 - BALTIMORE – Sparing, rather than resecting, a normal-appearing hippocampus in a patient with temporal lobe epilepsy is correlated with an increased risk of early seizure recurrence, according to an analysis presented at the annual meeting of the A.

Dec 9th, 2019 - BALTIMORE – In a review of 43 temporal lobe epilepsy patients at Yale University in New Haven, Conn. , anteromedial temporal resection (AMTR) failed in every case in which initial ictal rhythm on scalp EEG spread beyond the medial temporal lobe to.

Dec 8th, 2019 - BALTIMORE – Older patients may have better outcomes at 1 year after resective surgery for epilepsy than the general population does, according to research presented at the annual meeting of the American Epilepsy Society. A tendency toward greater.

Mar 20th, 2019 - Removal of at least half of the piriform cortex is required to achieve freedom from seizures in the neurosurgical treatment of temporal lobe epilepsy (TLE), new research suggests. A proof-of-concept study conducted by investigators at University C...

Mar 13th, 2019 - NEW YORK (Reuters Health) - The odds that a patient will be seizure free after surgery for temporal lobe epilepsy are higher when the procedure includes piriform-cortex resection, researchers report. "The piriform cortex is part of the olfactory s...