ALLMedicine™ Epilepsy Center

Oct 3rd, 2022 - In the histopathological examination of treatment-resistant epilepsy, focal cortical dysplasia (FCD) is the most common diagnosis in the pediatric group. FCD is classified histopathologically according to the International League Against Epilepsy ...

Oct 3rd, 2022 - GABAergic interneurons play a role in regulating adult neurogenesis within the dentate gyrus (DG) of the hippocampus. Neurogenesis occurs within a stem cell niche in the subgranular zone (SGZ) of the DG. In this niche, populations of neural progen...

Oct 3rd, 2022 - The modified Atkins diet (MAD), a less restrictive form of the ketogenic diet (KD), has gained popularity and is proposed to be an alternative to the traditional KD in the management of drug-resistant epilepsy (DRE). However, the evidence to suppo...

Oct 1st, 2022 - Metabolic disturbance has been reported in patients with epilepsy. Still, the evidence about the causal role of metabolites in facilitating or preventing epilepsy is lacking. Systematically investigating the causality between blood metabolites and...

Sep 30th, 2022 - Temporal lobe epilepsy (TLE) is one of the most common subtypes of focal epilepsy, with mesial temporal sclerosis (MTS) being a common radiological and histopathological finding. Accurate identification of MTS during presurgical evaluation confers...

Mar 6th, 2021 - The objective of this clinical practice guideline (CPG) is to provide recommendations for healthcare personnel working with patients with epilepsy on the use of wearable devices for automated seizure detection in patients with epilepsy, in outpati...

Nov 18th, 2020 - Pyridoxine-dependent epilepsy (PDE-ALDH7A1) is an autosomal recessive condition due to a deficiency of α-aminoadipic semialdehyde dehydrogenase, which is a key enzyme in lysine oxidation. PDE-ALDH7A1 is a developmental and epileptic encephalopathy...

Jun 15th, 2018 - To update the 2004 American Academy of Neurology guideline for managing treatment-resistant (TR) epilepsy with second- and third-generation antiepileptic drugs (AEDs). 2004 criteria were used to systemically review literature (January 2003 to Nove...

Apr 26th, 2017 - To determine the incidence rates of sudden unexpected death in epilepsy (SUDEP) in different epilepsy populations and address the question of whether risk factors for SUDEP have been identified. Systematic review of evidence; modified Grading Reco...

Jun 10th, 2009 - A committee assembled by the American Academy of Neurology (AAN) reassessed the evidence related to the care of women with epilepsy (WWE) during pregnancy, including antiepileptic drug (AED) teratogenicity and adverse perinatal outcomes. It is hig...

Aug 11th, 2022 - Most patients with drug-resistant epilepsy should receive a referral for a surgical evaluation as soon as it’s clear their disease is drug resistant, according to expert consensus recommendations from the International League Against Epilepsy (ILA...

Feb 16th, 2022 - Seizure phobia occurs in nearly one-third of people with epilepsy (PWE), but was mainly associated with variables not related to epilepsy, based on data from 69 adults. Anxiety and depression are known to affect quality of life in epilepsy patient...

Feb 14th, 2022 - The International League Against Epilepsy (ILAE) has issued recommendations for treating depression in patients with epilepsy. The new guidance highlights the high prevalence of depression among patients with epilepsy while offering the first syst...

Jan 7th, 2022 - Among antiseizure medications (ASMs) used as monotherapy in poststroke epilepsy (PSE), lamotrigine is associated with the lowest risk for mortality and valproic acid is associated with the highest risk, new research suggests. Investigators assesse...

Dec 30th, 2021 - A traumatic brain injury (TBI), even a mild type, can lead to post-traumatic epilepsy (PTE) up to a year after the head injury occurs, new research suggests. Results from a multicenter, prospective cohort study showed 2.7% of nearly 1500 participa...