ALLMedicine™ Epilepsy Center

May 19th, 2022 - To investigate the relevance of compartmentalized grey matter (GM) pathology and network reorganization in MS patients with concomitant epilepsy. From 3T MRI scans of 30 MS patients with epilepsy (MSE; age 41±15 years, 21 females, disease duration...

May 19th, 2022 - The progressive nature of epileptogenesis raises the question of whether the latent period may already carry information about the characteristics of the subsequent epilepsy. This study aimed to explore whether the time from stroke to epilepsy ons...

May 18th, 2022 - Glioma-related epilepsy (GRE) is a common symptom in patients with diffuse gliomas. However, the underlying mechanisms of GRE remain unclear. The current study aimed to investigate the underlying epileptogenic mechanisms of GRE through RNA sequenc...

May 16th, 2022 - The relationship between post-traumatic stress disorder (PTSD) and focal epilepsy is poorly understood. It has been hypothesized that there is a complex and reciprocal potential reinforcement of the symptoms of each condition. In this study, we in...

May 14th, 2022 - The Patient Information Leaflet (PIL) is an authoritative document that all people with epilepsy (PWE) in the European Union receive when prescribed anti-seizure medication (ASM). We undertook the first independent, comprehensive assessment to det...

Mar 6th, 2021 - The objective of this clinical practice guideline (CPG) is to provide recommendations for healthcare personnel working with patients with epilepsy on the use of wearable devices for automated seizure detection in patients with epilepsy, in outpati...

Nov 18th, 2020 - Pyridoxine-dependent epilepsy (PDE-ALDH7A1) is an autosomal recessive condition due to a deficiency of α-aminoadipic semialdehyde dehydrogenase, which is a key enzyme in lysine oxidation. PDE-ALDH7A1 is a developmental and epileptic encephalopathy...

Jun 15th, 2018 - To update the 2004 American Academy of Neurology guideline for managing treatment-resistant (TR) epilepsy with second- and third-generation antiepileptic drugs (AEDs). 2004 criteria were used to systemically review literature (January 2003 to Nove...

Apr 26th, 2017 - To determine the incidence rates of sudden unexpected death in epilepsy (SUDEP) in different epilepsy populations and address the question of whether risk factors for SUDEP have been identified. Systematic review of evidence; modified Grading Reco...

Jun 10th, 2009 - A committee assembled by the American Academy of Neurology (AAN) reassessed the evidence related to the care of women with epilepsy (WWE) during pregnancy, including antiepileptic drug (AED) teratogenicity and adverse perinatal outcomes. It is hig...

Feb 16th, 2022 - Seizure phobia occurs in nearly one-third of people with epilepsy (PWE), but was mainly associated with variables not related to epilepsy, based on data from 69 adults. Anxiety and depression are known to affect quality of life in epilepsy patient...

Feb 14th, 2022 - The International League Against Epilepsy (ILAE) has issued recommendations for treating depression in patients with epilepsy. The new guidance highlights the high prevalence of depression among patients with epilepsy while offering the first syst...

Jan 7th, 2022 - Among antiseizure medications (ASMs) used as monotherapy in poststroke epilepsy (PSE), lamotrigine is associated with the lowest risk for mortality and valproic acid is associated with the highest risk, new research suggests. Investigators assesse...

Dec 30th, 2021 - A traumatic brain injury (TBI), even a mild type, can lead to post-traumatic epilepsy (PTE) up to a year after the head injury occurs, new research suggests. Results from a multicenter, prospective cohort study showed 2.7% of nearly 1500 participa...

Nov 22nd, 2021 - Hypertension is associated with more than a twofold increased risk of developing late-onset epilepsy (LOE) even in patients who have not had a previous stroke, new research suggests. After excluding individuals with normal blood pressure who were ...