ALLMedicine™ Epilepsy Center

Feb 4th, 2023 - Myoclonus can be epileptic or nonepileptic. Epileptic myoclonus has been defined in clinical, neurophysiological, and neuroanatomical terms. Juvenile myoclonic epilepsy (JME) is typically considered to be an adolescent-onset idiopathic generalized...

Feb 4th, 2023 - Post-stroke epilepsy (PSE) is associated with increased morbidity and mortality. This study aimed to develop and validate a novel prediction model combining clinical factors and radiomics features to accurately identify patients at high risk of de...

Feb 4th, 2023 - To evaluate the ability of semiology alone in localising the epileptogenic zone (EZ) in people with frontal lobe epilepsy (FLE) who underwent resective surgery. We examined data on all individuals who had FLE surgery at our centre between January ...

Feb 3rd, 2023 - Proper seizure control during pregnancy and postpartum is essential to optimize the outcome of women with epilepsy (WWE). The current work aimed to address factors related to seizure occurrence during pregnancy and postpartum. One hundred twenty-f...

Feb 3rd, 2023 - Pyridoxine-dependent epilepsy (PDE) is a rare seizure disorder usually presenting with neonatal seizures. Most cases are caused by biallelic pathogenic ALDH7A1variants. While anti-seizure medications are ineffective, pyridoxine provides seizure co...

Mar 6th, 2021 - The objective of this clinical practice guideline (CPG) is to provide recommendations for healthcare personnel working with patients with epilepsy on the use of wearable devices for automated seizure detection in patients with epilepsy, in outpati...

Nov 18th, 2020 - Pyridoxine-dependent epilepsy (PDE-ALDH7A1) is an autosomal recessive condition due to a deficiency of α-aminoadipic semialdehyde dehydrogenase, which is a key enzyme in lysine oxidation. PDE-ALDH7A1 is a developmental and epileptic encephalopathy...

Jun 15th, 2018 - To update the 2004 American Academy of Neurology guideline for managing treatment-resistant (TR) epilepsy with second- and third-generation antiepileptic drugs (AEDs). 2004 criteria were used to systemically review literature (January 2003 to Nove...

Apr 26th, 2017 - To determine the incidence rates of sudden unexpected death in epilepsy (SUDEP) in different epilepsy populations and address the question of whether risk factors for SUDEP have been identified. Systematic review of evidence; modified Grading Reco...

Jun 10th, 2009 - A committee assembled by the American Academy of Neurology (AAN) reassessed the evidence related to the care of women with epilepsy (WWE) during pregnancy, including antiepileptic drug (AED) teratogenicity and adverse perinatal outcomes. It is hig...

Dec 5th, 2022 - NASHVILLE, Tennessee ― Targeting relevant sleep problems for patients with refractory temporal lobe epilepsy (TLE) improves cognition, results of a new, double-blind, randomized controlled trial suggest. Study findings show significant improvement...

Aug 11th, 2022 - Most patients with drug-resistant epilepsy should receive a referral for a surgical evaluation as soon as it’s clear their disease is drug resistant, according to expert consensus recommendations from the International League Against Epilepsy (ILA...

Feb 16th, 2022 - Seizure phobia occurs in nearly one-third of people with epilepsy (PWE), but was mainly associated with variables not related to epilepsy, based on data from 69 adults. Anxiety and depression are known to affect quality of life in epilepsy patient...

Feb 14th, 2022 - The International League Against Epilepsy (ILAE) has issued recommendations for treating depression in patients with epilepsy. The new guidance highlights the high prevalence of depression among patients with epilepsy while offering the first syst...

Jan 7th, 2022 - Among antiseizure medications (ASMs) used as monotherapy in poststroke epilepsy (PSE), lamotrigine is associated with the lowest risk for mortality and valproic acid is associated with the highest risk, new research suggests. Investigators assesse...