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About 9,663 results

ALLMedicine™ Epilepsy Center

Research & Reviews  3,279 results

Focal cortical dysplasia pathology: diagnostic difficulty, classification, and utility ...
https://doi.org/10.3171/2022.7.FOCUS21731
Neurosurgical Focus; Kapar O, Gurkan ZM et. al.

Oct 3rd, 2022 - In the histopathological examination of treatment-resistant epilepsy, focal cortical dysplasia (FCD) is the most common diagnosis in the pediatric group. FCD is classified histopathologically according to the International League Against Epilepsy ...

Hippocampal transplants of fetal GABAergic progenitors regulate adult neurogenesis in m...
https://doi.org/10.1016/j.nbd.2022.105879
Neurobiology of Disease; Arshad MN, Oppenheimer S et. al.

Oct 3rd, 2022 - GABAergic interneurons play a role in regulating adult neurogenesis within the dentate gyrus (DG) of the hippocampus. Neurogenesis occurs within a stem cell niche in the subgranular zone (SGZ) of the DG. In this niche, populations of neural progen...

Modified Atkins diet versus ketogenic diet in children with drug-resistant epilepsy: A ...
https://doi.org/10.1016/j.clnesp.2022.09.004
Clinical Nutrition ESPEN; Mhanna A, Mhanna M et. al.

Oct 3rd, 2022 - The modified Atkins diet (MAD), a less restrictive form of the ketogenic diet (KD), has gained popularity and is proposed to be an alternative to the traditional KD in the management of drug-resistant epilepsy (DRE). However, the evidence to suppo...

Assessing the causal association between human blood metabolites and the risk of epilepsy.
https://doi.org/10.1186/s12967-022-03648-5
Journal of Translational Medicine; Cai J, Li X et. al.

Oct 1st, 2022 - Metabolic disturbance has been reported in patients with epilepsy. Still, the evidence about the causal role of metabolites in facilitating or preventing epilepsy is lacking. Systematically investigating the causality between blood metabolites and...

Mapping hippocampal glutamate in mesial temporal lobe epilepsy with glutamate weighted ...
https://doi.org/10.1002/hbm.26083
Human Brain Mapping; Lucas A, Nanga RPR et. al.

Sep 30th, 2022 - Temporal lobe epilepsy (TLE) is one of the most common subtypes of focal epilepsy, with mesial temporal sclerosis (MTS) being a common radiological and histopathological finding. Accurate identification of MTS during presurgical evaluation confers...

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Guidelines  9 results

Automated seizure detection using wearable devices: A clinical practice guideline of th...
https://doi.org/10.1111/epi.16818
Epilepsia Beniczky S, Wiebe S et. al.

Mar 6th, 2021 - The objective of this clinical practice guideline (CPG) is to provide recommendations for healthcare personnel working with patients with epilepsy on the use of wearable devices for automated seizure detection in patients with epilepsy, in outpati...

Consensus guidelines for the diagnosis and management of pyridoxine-dependent epilepsy ...
https://doi.org/10.1002/jimd.12332
Journal of Inherited Metabolic Disease; Coughlin CR, Tseng LA et. al.

Nov 18th, 2020 - Pyridoxine-dependent epilepsy (PDE-ALDH7A1) is an autosomal recessive condition due to a deficiency of α-aminoadipic semialdehyde dehydrogenase, which is a key enzyme in lysine oxidation. PDE-ALDH7A1 is a developmental and epileptic encephalopathy...

Practice guideline update summary: Efficacy and tolerability of the new antiepileptic d...
https://doi.org/10.1212/WNL.0000000000005756
Neurology Kanner AM, Ashman E et. al.

Jun 15th, 2018 - To update the 2004 American Academy of Neurology guideline for managing treatment-resistant (TR) epilepsy with second- and third-generation antiepileptic drugs (AEDs). 2004 criteria were used to systemically review literature (January 2003 to Nove...

Practice guideline summary: Sudden unexpected death in epilepsy incidence rates and ris...
https://doi.org/10.1212/WNL.0000000000003685
Neurology Harden C, Tomson T et. al.

Apr 26th, 2017 - To determine the incidence rates of sudden unexpected death in epilepsy (SUDEP) in different epilepsy populations and address the question of whether risk factors for SUDEP have been identified. Systematic review of evidence; modified Grading Reco...

Management issues for women with epilepsy-Focus on pregnancy (an evidence-based review)...
https://doi.org/10.1111/j.1528-1167.2009.02129.x
Epilepsia Harden CL, Meador KJ et. al.

Jun 10th, 2009 - A committee assembled by the American Academy of Neurology (AAN) reassessed the evidence related to the care of women with epilepsy (WWE) during pregnancy, including antiepileptic drug (AED) teratogenicity and adverse perinatal outcomes. It is hig...

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Drugs  476 results see all →

News  92 results

Earlier Surgical Referral Needed for Drug-Resistant Epilepsy
https://www.medscape.com/viewarticle/979082

Aug 11th, 2022 - Most patients with drug-resistant epilepsy should receive a referral for a surgical evaluation as soon as it’s clear their disease is drug resistant, according to expert consensus recommendations from the International League Against Epilepsy (ILA...

Seizure Phobia a 'Distinct Anxiety Disorder' in Epilepsy
https://www.medscape.com/viewarticle/968614

Feb 16th, 2022 - Seizure phobia occurs in nearly one-third of people with epilepsy (PWE), but was mainly associated with variables not related to epilepsy, based on data from 69 adults. Anxiety and depression are known to affect quality of life in epilepsy patient...

ILAE Offers First Guide to Treating Depression in Epilepsy
https://www.medscape.com/viewarticle/968481

Feb 14th, 2022 - The International League Against Epilepsy (ILAE) has issued recommendations for treating depression in patients with epilepsy. The new guidance highlights the high prevalence of depression among patients with epilepsy while offering the first syst...

Lamotrigine Linked to Lowest Mortality Risk in Poststroke Epilepsy
https://www.medscape.com/viewarticle/966285

Jan 7th, 2022 - Among antiseizure medications (ASMs) used as monotherapy in poststroke epilepsy (PSE), lamotrigine is associated with the lowest risk for mortality and valproic acid is associated with the highest risk, new research suggests. Investigators assesse...

Post-traumatic Epilepsy Common Even After 'Mild' TBI
https://www.medscape.com/viewarticle/965809

Dec 30th, 2021 - A traumatic brain injury (TBI), even a mild type, can lead to post-traumatic epilepsy (PTE) up to a year after the head injury occurs, new research suggests. Results from a multicenter, prospective cohort study showed 2.7% of nearly 1500 participa...

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Patient Education  9 results see all →