About 2,455 results

ALLMedicine™ Generalized Tonic-clonic Seizures Center

Research & Reviews  411 results

Severe autonomic nervous system imbalance in Lennox-Gastaut syndrome patients demonstra...
Epilepsy Research; Hödl S, Olbert E et. al.

Oct 10th, 2021 - Patients diagnosed with Lennox Gastaut syndrome (LGS), an epileptic encephalopathy characterized by usually drug resistant generalized and focal seizures, are often considered as candidates for vagus nerve stimulation (VNS). Recent research shows ...

Generalized tonic-clonic seizures are accompanied by changes of interrelations within t...
Epilepsy & Behavior : E&B; Vieluf S, Hasija T et. al.

Oct 9th, 2021 - A seizure is a strong central stimulus that affects multiple subsystems of the autonomic nervous system (ANS), and results in different interactions across ANS modalities. Here, we aimed to evaluate whether multimodal peripheral ANS measures demon...

Epilepsy stigma in the Republic of Guinea and its socioeconomic and clinical associatio...
Epilepsy Research; Rice DR, Cisse FA et. al.

Oct 8th, 2021 - We aim to quantify the degree of epilepsy stigma perceived by people living with epilepsy (PLWE) in the Republic of Guinea (2019 gross national income per capita, 930 USD) and analyze the demographic, social, and clinical factors associated with e...

The effect of lamotrigine and other antiepileptic drugs on respiratory rhythm generatio...
Epilepsia Layer N, Brandes J et. al.

Sep 24th, 2021 - Lamotrigine and other sodium-channel blocking agents are among the most commonly used antiepileptic drugs (AEDs). Because other sodium channel blockers, such as riluzole, can severely alter respiratory rhythm generation during hypoxia, we wanted t...

Alcohol Withdrawal Syndrome: Outpatient Management.
American Family Physician; Tiglao SM, Meisenheimer ES et. al.

Sep 16th, 2021 - Approximately one-half of patients with alcohol use disorder who abruptly stop or reduce their alcohol use will develop signs or symptoms of alcohol withdrawal syndrome. The syndrome is due to overactivity of the central and autonomic nervous syst...

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Guidelines  1 results

Practice guideline update summary: Efficacy and tolerability of the new antiepileptic d...
Neurology Kanner AM, Ashman E et. al.

Jun 15th, 2018 - To update the 2004 American Academy of Neurology (AAN) guideline for treating new-onset focal or generalized epilepsy with second- and third-generation antiepileptic drugs (AEDs). The 2004 AAN criteria were used to systematically review literature...

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Drugs  522 results see all →

Clinicaltrials.gov  5 results

Study of Diazepam Buccal Film Administered in the Interictal and in the Ictal-Periictal States to Adults With Epilepsy

Sep 18th, 2020 - This was a Phase 2 multicenter, open-label, two-way study conducted in adult subjects to assess the bioavailability, pharmacokinetics, and safety of DBF during the Interictal Period and during the Ictal/peri-ictal Period, with a minimum of 14 days...

Compassionate Use Program With Lacosamide in Patients With Partial-onset or Generalized Tonic-clonic Seizures

Oct 31st, 2019 - The objective of this Compassionate Use Program (CUP) is to provide continued access to Lacosamide (LCM) for monotherapy use for patients who were receiving LCM in SP0993 and SP0994 at the time of study unblinding and close of SP0994, and who bene...

Trial to Demonstrate the Efficacy and Safety of Conversion to Lacosamide Monotherapy for Partial-onset Seizures

Jul 19th, 2018 - Sudden unexplained death in epilepsy have been reported in epilepsy patients. A causal relationship with the administration of antiepileptic drugs has not been established. The most important known risk factor for sudden unexplained death in epile...

Does Memantine Improve Verbal Memory Task Performance in Subjects With Partial Epilepsy and Memory Dysfunction?

Jul 11th, 2017 - Patients with epilepsy frequently demonstrate subtle cognitive difficulties in the setting of otherwise normal intelligence. Those with left temporal lobe seizures often have particular deficits in verbal memory (Blum 2001). These memory difficult...

A Study of the Efficacy and Safety of Topiramate in Epilepsy Patients With Primary Generalized Tonic-clonic Seizures

Jun 8th, 2011 - Epilepsy is a disease characterized by seizures, which are abnormal electrical discharges in the brain that temporarily disrupt normal brain function. Seizures are classified as "generalized," involving all or most of the brain at the same time, o...

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News  43 results

How to identify, evaluate, and treat patients with ‘Percocet use disorder’
Faisal A. Islam, MD, MBA, BCMAS, Zia Choudhry, MD, PhD, MBA

Dec 7th, 2020 - In recent years, Percocet (oxycodone/paracetamol) has experienced a meteoric rise to prominence because of the presence of conspicuous references in pop culture and the ever-evolving hip-hop scene,1 so much so that even propafenone is being mislab.

Your Brain on Cocoa; MS-Gut Link; Autism and Newborn Hearing

Nov 24th, 2020 - Young healthy adults had stronger, faster brain oxygenation responses after drinking high-flavanol cocoa and higher cognitive performance, but only when cognitive demands were high. (Scientific Reports) People with vitiligo had five times the risk...

Car Accidents Common With Undetected Epilepsy

Oct 20th, 2020 - Focal epilepsy patients with hard-to-detect, subtle seizures experienced long delays to diagnoses and treatment, and those delays were tied to a high occurrence of motor vehicle accidents, a cross-sectional study showed. Among 246 focal epilepsy p...

Little Evidence to Support Treatments for Prevention of Sudden Unexpected Death in Epilepsy

Apr 17th, 2020 - NEW YORK (Reuters Health) - More research is needed to identify effective interventions aimed at preventing sudden unexpected death in patients with epilepsy (SUDEP), according to an updated Cochrane review. SUDEP occurs with an incidence of 1 to ...

Levetiracetam Oral Solution Recalled in US

Dec 20th, 2019 - Lannett Company Inc has voluntarily recalled two lots of levetiracetam oral solution (100 mg/mL) to the consumer level because of contamination with Bacillus subtilis, which was identified during an evaluation of a raw material used to manufacture...

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