ALLMedicine™ Ischemic Stroke Center

Oct 5th, 2022 - Background Ischemic stroke is likely caused by interactions of multiple genes and environmental determinants. However, large-scale sequencing studies to discern functional genetic variants and their interactions with clinical and lifestyle risk fa...

Oct 5th, 2022 - Background Trimethylamine N-oxide (TMAO) contributes to cardiovascular disease through its prothrombotic, proatherothrombotic, and proinflammatory effects. We aimed to evaluate whether residual risk of recurrent stroke of TMAO and its precursor ch...

Oct 5th, 2022 - Background A target mismatch profile can identify good clinical response to recanalization after acute ischemic stroke, but does not consider region specificities. Purpose To test whether location-weighted infarction core and mismatch, determined ...

Oct 5th, 2022 - This study investigated how peripheral axonal excitability changes in ischemic stroke patients with hemiparesis or hemiplegia, reflecting the plasticity of motor axons due to corticospinal tract alterations along the poststroke stage. Each subject...

Oct 4th, 2022 - The drug 3-n-butylphthalide (NBP) was developed and approved in China, where it has been used to treat ischemic cerebrovascular diseases. It is also considered to have a neuroprotective effect. This study aimed to evaluate whether NBP combined wit...

Aug 24th, 2022 - Cardiovascular disease (CVD) is the leading cause of morbidity and death in the US and is the cause of more than 1 of every 4 deaths. Coronary heart disease is the single leading cause of death and accounts for 43% of deaths attributable to CVD in...

Jul 25th, 2022 - Background and Purpose: The aim of this study was to investigate the association between daytime napping frequency and the incidence of essential hypertension or stroke as well as to validate causality in this relationship via Mendelian randomiza...

Jan 26th, 2022 - Atrial fibrillation (AF) is the most common cardiac arrhythmia. The prevalence of AF increases with age, from less than 0.2% in adults younger than 55 years to about 10% in those 85 years or older, with a higher prevalence in men than in women. It...

Dec 14th, 2021 - Overview: Ischemic stroke is a leading cause of death and disability throughout the world. Antithrombotic therapy, which includes both antiplatelet and anticoagulant agents, is a primary medication of choice for the secondary prevention of stroke....

Mar 12th, 2021 - Ischemic stroke remains the fifth leading cause of death in the United States. Nurses play a pivotal role in the care of patients throughout the continuum. With the advances in stroke care, including mechanical thrombectomy, the American Heart Ass...

Sep 30th, 2022 - A randomized, double blind, multicenter, multinational, placebo controlled, parallel group, single dose, adaptive phase II/III study. The study will be conducted in 3 consecutive parts, each separated from the preceding one by an interim analysis ...

Sep 30th, 2022 - Control group: Mechanical thrombectomy followed by the guideline recommended treatment for acute ischemic stroke; Experimental group: After mechanical thrombectomy, head acupuncture and the treatment regimen recommended by the guideline for acute ...

Sep 29th, 2022 - The primary objective of this study is to evaluate the effectiveness of early treatment with evolocumab plus routine lipid management vs routine lipid management alone when administered in the acute setting to reduce myocardial infarction, ischemi...

Sep 29th, 2022 - The purpose of this study is to evaluate the initial safety and performance of the RapidPulse Inc. RapidPulseTM Aspiration System as frontline approach for use in the treatment of patients with Acute Ischemic Stroke (AIS) due to Large Vessel Occlu...

Sep 29th, 2022 - This study will evaluate the efficacy and safety of tenecteplase compared with placebo in participants with acute ischemic stroke (AIS). All participants will receive standard-of-care therapy according to AmericanHeart Association/American Stroke ...

Oct 5th, 2022 - Rates of major ischemic and hemorrhagic vascular events are higher among patients with a prior intracerebral hemorrhage (ICH) in comparison with the general population, a new study shows. The finding emphasizes the need for better secondary preven...

Oct 4th, 2022 - The study covered in this summary was published on ResearchSquare.com as a preprint and has not yet been peer reviewed. Key Takeaways The study reported that atrial fibrillation (AF) was an independent risk factor for poor clinical outcomes among ...

Oct 3rd, 2022 - Guidelines for the management of patients with intracranial atherosclerotic disease (ICAD) were published in September 2022 by the European Stroke Organisation (ESO) in European Stroke Journal.[1] Oral anticoagulation is not recommended over aspir...

Sep 29th, 2022 - Women Earn Less From Drug, Device Firms Female physicians earn far less in compensation from drug and medical device companies than do their male peers, new research shows. In fact, the gender-based pay disparity widened from 2013 to 2019, accordi...

Sep 26th, 2022 - A look at the top cardiovascular disease (CVD) diagnoses in US emergency departments (EDs) suggests that many heart-related emergencies are due to poorly controlled high blood pressure. In a study of more than 20 million ED visits, about one third...