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About 5,400 results

ALLMedicine™ Myasthenia Gravis Center

Research & Reviews  1,898 results

Pembrolizumab-induced Myasthenia Gravis: Literature Review of Ocular Manifestations and...
https://doi.org/10.1097/CJI.0000000000000422 10.1186/s12883-019-1416-1. 10.1093/omcr/omy094
Journal of Immunotherapy (Hagerstown, Md. : 1997); Dugena O, Zheng C et. al.

May 17th, 2022 - Immune checkpoint inhibition is a new and promising therapy approved for the treatment of various malignancies. Pembrolizumab is a potent tumor suppressor that acts by upregulating the immune system to recognize cancer cells which may result in di...

Development, Characterization, and in vivo Validation of a Humanized C6 Monoclonal Anti...
https://doi.org/10.1159/000524587
Journal of Innate Immunity; Gytz Olesen H, Michailidou I et. al.

May 14th, 2022 - Damage and disease of nerves activates the complement system. We demonstrated that activation of the terminal pathway of the complement system leads to the formation of the membrane attack complex (MAC) and delays regeneration in the peripheral ne...

Refractory post-thymectomy myasthenia gravis with onset at MGFA stage V: a case report.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9097348
Journal of Cardiothoracic Surgery; Zhou RQ, Li LJ et. al.

May 14th, 2022 - Post-thymectomy myasthenia gravis (PTMG) is defined as thymoma patients without signs of myasthenia gravis (MG) pre-operation, but develop MG after radical surgical resection. PTMG might be misdiagnosed not only because of its rare incidence, but ...

A Study to Evaluate Rozanolixizumab in Study Participants With Generalized Myasthenia Gravis
https://clinicaltrials.gov/ct2/show/NCT04650854

May 13th, 2022 - The purpose of this study is to assess the safety, tolerability and efficacy of additional 6-week treatment cycles with rozanolixizumab in study participants with generalized myasthenia gravis (gMG).

Oculopharyngeal muscular dystrophy coexisting with myasthenia gravis.
https://doi.org/10.1136/practneurol-2022-003429
Practical Neurology; Alungulese AL, García Soldevilla MA et. al.

May 10th, 2022 - Oculopharyngeal muscular dystrophy (OPMD) and myasthenia gravis are both rare conditions of different pathophysiological nature, so a fortuitous association is unlikely. However, antiacetylcholine receptor antibodies may be found in other genetic ...

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Guidelines  4 results

Guidance for the management of myasthenia gravis (MG) and Lambert-Eaton myasthenic synd...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105910
Journal of the Neurological Sciences; , Jacob S et. al.

Apr 5th, 2020 - Guidance for the management of myasthenia gravis (MG) and Lambert-Eaton myasthenic syndrome (LEMS) during the COVID-19 pandemic.|2020| ,Jacob S,Muppidi S,Guidon A,Guptill J,|complications,drug therapy,epidemiology,therapeutic use,therapeutic use,t...

The Association of British Neurologists' myasthenia gravis guidelines.
https://doi.org/10.1111/nyas.13503
Annals of the New York Academy of Sciences; Sussman J, Farrugia ME et. al.

Nov 10th, 2017 - Myasthenia gravis (MG) is an autoimmune disease of the neuromuscular junction for which many therapies were developed before the era of evidence-based medicine. Despite the basic principles of treatment being well known, patients continue to recei...

Clinical Practice Guidelines for Sustained Neuromuscular Blockade in the Adult Critical...
https://doi.org/10.1097/CCM.0000000000002027
Critical Care Medicine; Murray MJ, DeBlock H et. al.

Oct 19th, 2016 - To update the 2002 version of "Clinical practice guidelines for sustained neuromuscular blockade in the adult critically ill patient." A Task Force comprising 17 members of the Society of Critical Medicine with particular expertise in the use of n...

International consensus guidance for management of myasthenia gravis: Executive summary.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977114
Neurology Sanders DB, Wolfe GI et. al.

Jul 1st, 2016 - To develop formal consensus-based guidance for the management of myasthenia gravis (MG). In October 2013, the Myasthenia Gravis Foundation of America appointed a Task Force to develop treatment guidance for MG, and a panel of 15 international expe...

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Drugs  55 results see all →

Clinicaltrials.gov  50 results

A Study to Evaluate Rozanolixizumab in Study Participants With Generalized Myasthenia Gravis
https://clinicaltrials.gov/ct2/show/NCT04650854

May 13th, 2022 - The purpose of this study is to assess the safety, tolerability and efficacy of additional 6-week treatment cycles with rozanolixizumab in study participants with generalized myasthenia gravis (gMG).

Comparative Study Between Frontalis Flap Advancement Versus Frontalis Sling Operations in Mangment of Congenital Blepharoptosis
https://clinicaltrials.gov/ct2/show/NCT05358002

May 3rd, 2022 - - Population of study & disease condition: Congenital ptosis with poor levator muscle function. - Study setting: The ophthalmology unit of Abuelreesh Children Hospital. - Inclusion criteria: Criteria for inclusion in this study will be children mo...

Pressure Injury Treatment by Intermittent Electrical Stimulation:
https://clinicaltrials.gov/ct2/show/NCT05085288

May 3rd, 2022 - This is a two-arm, prospective randomized control trial assessing whether IES combined with the standard of care (treatment) is superior to the standard of care alone (control). The study is a parallel design, adaptive, non-blinded randomized cont...

Interleukin and Autoantibodies in Myasthenia Gravis.
https://clinicaltrials.gov/ct2/show/NCT05301153

May 3rd, 2022 - Follicular T cells play a vital role during autoimmune disorders. The enhanced number or activation of these cells results in hyperproliferation of autoreactive B cells and overproduction of antibodies. Interleukin-37 is a newly identified immune-...

Efficacy and Safety of Low-dose Rituximab in the Treatment of Refractory Myasthenia Gravis
https://clinicaltrials.gov/ct2/show/NCT05332587

May 2nd, 2022 - This study is designed to evaluate the effectiveness and safety of low-dose rituximab in patients with refractory myasthenia gravis. The traditional treatment of MG is immunosuppressive therapy, usually beginning with corticosteroids. However, up ...

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News  141 results

Two Investigational Meds Promising for Myasthenia Gravis
https://www.medscape.com/viewarticle/974080

May 16th, 2022 - Two investigational medications are safe and effective for the treatment of generalized myasthenia gravis (gMG), new research shows. The phase 3 studies showed both zilucoplan and rozanolixizumab improve gMG-specific outcomes compared with placebo...

First Human Bird Flu Case in U.S.; Okla. Nears Abortion Ban; Ebola Outbreak in DRC
https://www.medpagetoday.com/infectiousdisease/covid19/98463

Apr 29th, 2022 - Note that some links may require registration or subscription. CDC confirmed the first human case of the H5N1 bird flu in the U.S., in a Colorado man with direct exposure to birds. Oklahoma Gov. Kevin Stitt (R) is expected to sign a "Texas-style" ...

Rapid Rx Quiz: Myasthenia Gravis Treatments
https://www.medscape.com/viewarticle/970022

Mar 15th, 2022 - Myasthenia gravis (MG) is estimated to affect as many as 60,000 patients in the United States and more than 700,000 people worldwide. In approximately 10% of patients, complications can be life-threatening. However, with the right treatment, MG ca...

Rapid Rx Quiz: Myasthenia Gravis Treatments
https://reference.medscape.com/viewarticle/970022

Mar 15th, 2022 - Myasthenia gravis (MG) is estimated to affect as many as 60,000 patients in the United States and more than 700,000 people worldwide. In approximately 10% of patients, complications can be life-threatening. However, with the right treatment, MG ca...

 Muscle-wasting Conditions May be More Common in the UK Than Previous Estimates
https://www.medscape.com/viewarticle/968599

Feb 16th, 2022 - Tens of thousands more people in the UK could be living with neuromuscular disease (NMD) than previous estimates suggested, according to new research. A study in the journal PLOS ONE, which analysed millions of GP records, suggested that the preva...

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Patient Education  12 results see all →