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ALLMedicine™ Sudden Unexpected Death In Epilepsy Center

Research & Reviews  523 results

The Epileptic Heart and the Case for Routine Use of the Electrocardiogram in Patients w...
https://doi.org/10.1016/j.ncl.2022.03.003
Neurologic Clinics; Verrier RL, Pang TD et. al.

Oct 22nd, 2022 - A dire complication associated with chronic epilepsy is abrupt premature death, currently referred to as sudden unexpected death in epilepsy (SUDEP). Although the traditional view has been that SUDEP is due primarily to peri-ictal respiratory fail...

Update on Sudden Unexpected Death in Epilepsy.
https://doi.org/10.1016/j.ncl.2022.06.001
Neurologic Clinics; Kløvgaard M, Sabers A et. al.

Oct 22nd, 2022 - Persons with epilepsy (PWE) have an up to 34-fold increased risk of dying suddenly and unexpectedly compared with the general population. Despite being potentially preventable by optimal care, sudden unexpected death in epilepsy (SUDEP) is one of ...

Sudden Unexpected Death in Epilepsy: Pathogenesis, Risk Factors, and Prevention.
https://doi.org/10.1055/a-1960-1355
Seminars in Neurology; Haridas B, Chuang DT et. al.

Oct 13th, 2022 - Sudden unexpected death in epilepsy (SUDEP) is a tragic and unexpected cause of death in patients with a known diagnosis of epilepsy. It occurs in up to 6.3 to 9.3/1,000 patients with drug-resistant epilepsy. The main three risk factors associated...

Progressive slowing of clonic phase predicts postictal generalized EEG suppression.
https://doi.org/10.1111/epi.17434
Epilepsia Vlachou M, Ryvlin P et. al.

Oct 9th, 2022 - Postictal generalized electroencephalography (EEG) suppression (PGES) is a surrogate marker of sudden unexpected death in epilepsy (SUDEP). It is still unclear which ictal phenomena lead to prolonged PGES and increased risk of SUDEP. Semiology fea...

Carotid body stimulation as a potential intervention in sudden death in epilepsy.
https://doi.org/10.1016/j.yebeh.2022.108918
Epilepsy & Behavior : E&B; Biggs EN, Budde RB et. al.

Oct 7th, 2022 - To investigate carotid body (CB) mechanisms related to sudden death during seizure. Ictal activation of oxygen-conserving reflexes (OCRs) can trigger fatal cardiorespiratory collapse in seizing rats, which presents like human sudden unexpected dea...

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Guidelines  1 results

Practice guideline summary: Sudden unexpected death in epilepsy incidence rates and ris...
https://doi.org/10.1212/WNL.0000000000003685
Neurology Harden C, Tomson T et. al.

Apr 26th, 2017 - To determine the incidence rates of sudden unexpected death in epilepsy (SUDEP) in different epilepsy populations and address the question of whether risk factors for SUDEP have been identified. Systematic review of evidence; modified Grading Reco...

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Clinicaltrials.gov  13 results

Phenomenological Approach of Epilepsy in Patients With Epilepsy
https://clinicaltrials.gov/ct2/show/NCT02952456

Aug 11th, 2022 - Rationale: Persons with epilepsy have a greater risk of incurring accidental injury and a higher mortality risk than the general population. Study Objective : To understand life experience of the disease and risks associated with epilepsy in patie...

Stimulation of the Thalamus for Arousal Restoral in Temporal Lobe Epilepsy
https://clinicaltrials.gov/ct2/show/NCT04897776

Jul 11th, 2022 - Impaired consciousness during seizures has a major negative impact on quality of life for people with epilepsy. Consequences include risk of motor vehicle accidents, drowning, poor work and school performance, and social stigmatization. Impaired i...

Electroclinical Features of Sudden Unexpected Death in Epilepsy (SUDEP) : a Multi-center Observational Study
https://clinicaltrials.gov/ct2/show/NCT05423990

Jun 21st, 2022 - Sudden unexpected death in epilepsy (SUDEP) is regarded as a leading cause of premature death in epilepsy patients. We aim to capture the whole process of SUDEP and near-SUDEP occurrence in patients with epilepsy, and expolre video-electroencephal...

LEONIDaS Caregivers Study
https://clinicaltrials.gov/ct2/show/NCT05140122

Dec 1st, 2021 - Dravet syndrome is a rare form of severe epilepsy that begins in the first year of life and is associated with frequent and/or prolonged seizures. Individuals with Dravet Syndrome often experience a range of comorbidities, including behavioral and...

Cardiac Rhythm Disturbances in Hard-to-treat Epilepsy Patients Using Loop ECG Recorders
https://clinicaltrials.gov/ct2/show/NCT03376087

Dec 7th, 2020 - Seizure-related cardiac arrhythmias are one of the possible causes of sudden unexpected death in epilepsy (SUDEP). Identification of these patients is challenging because cardiac rhythm disturbances could emerge only during seizures. Furthermore, ...

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News  90 results

FDA Okays New Med for Lennox-Gastaut Syndrome
https://www.medscape.com/viewarticle/971158

Mar 29th, 2022 - The US Food and Drug Administration (FDA) has approved fenfluramine (Fintepla) oral solution, a Schedule IV controlled substance, for the treatment of seizures associated with Lennox-Gastaut syndrome (LGS) in children aged 2 years and older, the c...

CPET in COVID Long-Haulers; Omicron Suspected at Conference; Aspirin a No-No in HF?
https://www.medpagetoday.com/cardiology/prevention/95932

Nov 30th, 2021 - Exercise-induced premature ventricular contractions occurring during recovery were bad news for asymptomatic people. (Journal of the American College of Cardiology) Cardiopulmonary exercise testing (CPET) revealed that some COVID-19 long-haulers w...

Deeper Sleep, Slower Heart Rate Tied to Sudden Death in Epilepsy
https://www.medscape.com/viewarticle/951137

May 14th, 2021 - Deeper sleep and slower heart rate following seizures may work synergistically to increase the risk for sudden unexpected death in epilepsy (SUDEP), new research suggests. Investigators analyzed data on 100 seizures in 42 patients with epilepsy. T...

COVID Vax & Myocarditis; Ejection Fractions on EKG; Southerners Still Unwell
https://www.medpagetoday.com/cardiology/prevention/92510

May 10th, 2021 - European regulators are looking into cases of myocarditis and pericarditis among people who got the Pfizer/BioNTech vaccine. (FiercePharma) Data from London and Wuhan, China show first-phase ejection fraction, a measure of preclinical heart failur...

COVID-19's Global Impact on Epilepsy
https://www.medscape.com/viewarticle/943001

Dec 21st, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Around the globe, the COVID-19 pandemic has placed an enormous strain on patients with epilepsy, new research shows. The pandemic also appears to ...

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