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About 450 results

ALLMedicine™ Hand-foot-and-mouth Disease Center

Research & Reviews  145 results

Identification of a novel acylthiourea-based potent broad-spectrum inhibitor for entero...
https://doi.org/10.1016/j.antiviral.2023.105583
Antiviral Research; Liu X, Xu Z et. al.

Mar 26th, 2023 - Enterovirus infections have become a serious public health threat to young children, leading to hand-foot-and-mouth disease and more severe nervous system diseases. Due to the lack of licensed anti enterovirus drugs, we reported herein that a Teno...

Impact of the COVID-19 pandemic on the epidemiology of other communicable diseases in J...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9837205
International Journal of Infectious Diseases : IJID : Off... Hirae K, Hoshina T et. al.

Jan 16th, 2023 - To elucidate the impact of the COVID-19 pandemic on the epidemiology of other infectious diseases. We investigated the epidemiology of 36 communicable diseases during 2015-2021 in Japan and compared the number of cases in each disease between the ...

TBK1 and IRF3 are potential therapeutic targets in Enterovirus A71-associated diseases.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9831319
PLoS Neglected Tropical Diseases; Ji W, Sun T et. al.

Jan 11th, 2023 - Enterovirus A71 (EV-A71) is an important causative agent of hand-foot-and-mouth disease (HFMD) associated with enormous healthcare and socioeconomic burden. Although a range of studies about EV-A71 pathogenesis have been well described, the underl...

Local immune dysregulation and subsequent inflammatory response contribute to pulmonary...
https://doi.org/10.1002/jmv.28454
Journal of Medical Virology; Sun T, Li D et. al.

Jan 5th, 2023 - Pulmonary edema that comes on suddenly is the leading cause of mortality in hand-foot-and-mouth disease (HFMD) patients; however, its pathogenesis is still largely unclear. A range of research suggest immunopathogenesis during the occurrence of pu...

The transfer of maternal antibodies and dynamics of maternal and natural infection-indu...
https://doi.org/10.1186/s12916-022-02604-w
BMC Medicine; Zhou J, Zhou Y et. al.

Nov 11th, 2022 - A major hand-foot-and-mouth disease (HFMD) pathogen, coxsackievirus A16 (CVA16), has predominated in several of the last 10 years and caused the largest number of HFMD outbreaks between 2011 and 2018 in China. We evaluated the efficacy of maternal...

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Clinicaltrials.gov  6 results

Safety and Immunogenicity of High-dose IN-B001 in Healthy Subjects
https://clinicaltrials.gov/ct2/show/NCT04637919

Nov 20th, 2020 - Enterovirus 71(EV71) and coxsackievirus A16(CVA16) are major causes of Hand-foot-and-mouth disease (HFMD) occurring in pediatric population. Although EV71 vaccine has been licensed in China, vaccine for CVA16-associated HFMD is currently not avail...

Safety and Immunogenicity of CJ-40010 in Healthy Subjects
https://clinicaltrials.gov/ct2/show/NCT04182932

Dec 3rd, 2019 - Enterovirus 71(EV71) and coxsackievirus A16(CVA16) are major causes of Hand-foot-and-mouth disease (HFMD) occurring in pediatric population. Although EV71 vaccine has been licensed in China, vaccine for CVA16-associated HFMD is currently not avail...

The Phase IVa of Inactivated Enterovirus 71 Vaccine (Human Diploid Cell, KMB-17)
https://clinicaltrials.gov/ct2/show/NCT02999828

Jan 23rd, 2018 - Enterovirus 71 (EV71), a major pathogen causing hand-foot-and-mouth disease (HFMD) worldwide, is a member of the Human Enterovirus species A, family Picornaviridae. Its infection occasionally leads to severe diseases and death, with central nervou...

A Protected Study of Inactivated EV71 Vaccine (Human Diploid Cell, KMB-17) in Chinese Infants and Children
https://clinicaltrials.gov/ct2/show/NCT01569581

Mar 12th, 2013 - Hand-foot-and-mouth disease (HFMD) is a significant cause of death, usually characterized by vesicular lesions on the skin and oral mucosa and high morbidity rates in children. Additionally, occasional fatal cases have been reported involving brai...

A Phase II, Safety and Efficacy Study of Inactivated EV 71 Vaccine (Human Diploid Cell, KMB-17) in Chinese Infants
https://clinicaltrials.gov/ct2/show/NCT01512706

Apr 27th, 2012 - Hand-foot-and-mouth disease (HFMD) is a significant cause of death, usually characterized by vesicular lesions on the skin and oral mucosa and high morbidity rates in children. Additionally, occasional fatal cases have been reported involving brai...

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News  17 results

Systemic Epstein-Barr Virus–Positive T-cell Lymphoma of Childhood
https://www.mdedge.com/dermatology/article/211566/pediatrics/systemic-epstein-barr-virus-positive-t-cell-lymphoma-childhood
Qiong Wu, MD, Faliang Ren, MD et. al.

Nov 5th, 2019 - Case Report A 7-year-old Chinese boy presented with multiple painful oral and tongue ulcers of 2 weeks’ duration as well as acute onset of moderate to high fever (highest temperature, 39. 3°C) for 5 days.

Guttate Psoriasis Following Presumed Coxsackievirus A
https://www.mdedge.com/dermatology/article/209343/psoriasis/guttate-psoriasis-following-presumed-coxsackievirus
Kevin M. Rychik, BS, Naghmeh Yousefzadeh, MD et. al.

Oct 3rd, 2019 - There are 4 variants of psoriasis: plaque, guttate, pustular, and erythroderma (in order of prevalence). 2 Guttate psoriasis is characterized by small, 2- to 10-mm, raindroplike lesions on the skin.

Hand-foot-and-mouth Disease Caused by Coxsackievirus A6 on the Rise
https://www.mdedge.com/dermatology/article/178644/pediatrics/hand-foot-and-mouth-disease-caused-coxsackievirus-a6-rise
Brooks David Kimmis, MD, Christopher Downing, MD et. al.

Nov 1st, 2018 - Hand-foot-and-mouth disease (HFMD) is a viral illness caused by several enteroviruses, most commonly coxsackievirus A16 (CVA16) and enterovirus 71 (EV71). The disease is generally seen in children younger than 5 years, characterized by lesions of.

Woman, 18, With Sore Throat, Fever, and Painful Rash
https://www.mdedge.com/clinicianreviews/article/173902/infectious-diseases/woman-18-sore-throat-fever-and-painful-rash
Jean Covino, DHSc, MPA, PA-C, Jennifer Hofmann, MS, PA-C

Sep 3rd, 2018 - IN THIS ARTICLE Diagnosis Management Outcome for the case patient An 18-year-old woman presents to urgent care with a one-day history of sudden-onset sore throat, chills, malaise, and fever (102. 5°F).

Lessons emerge from Europe’s first enterovirus-related brain stem encephalitis outbreak
https://www.mdedge.com/infectiousdisease/article/143629/infectious-diseases/lessons-emerge-europes-first-enterovirus
Bruce Jancin

Jul 31st, 2017 - MADRID – Ninety-two percent of Spanish children sickened during the first-ever outbreak of enterovirus-associated brain stem encephalitis in western Europe survived with no long-term sequelae, Nuria Worner, MD, reported at the annual meeting of th.

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Patient Education  12 results see all →