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About 920 results

ALLMedicine™ Neonatal Seizures Center

Research & Reviews  341 results

The Effect of AI-assisted cEEG Diagnosis on the Administration of Antiseizure Medication in Neonatal Seizures
https://clinicaltrials.gov/ct2/show/NCT05036395

Oct 12th, 2021 - The occurrence of neonatal seizures may be the first, and perhaps the only, clinical sign of a central nervous system disorder in the newborn infant. The promoted treatment of seizures can limit the secondary injury to the brain and positively aff...

Neonatal Seizure Management - Is the Timing of Treatment Critical?
https://doi.org/10.1016/j.jpeds.2021.09.058
The Journal of Pediatrics; Pavel AM, Rennie JM et. al.

Oct 10th, 2021 - To assess the impact of the time to treatment of the first electrographic seizure on subsequent seizure burden; secondary aim was to describe overall seizure management in a large neonatal cohort. Newborns (36-44 weeks' gestation) requiring electr...

Management of seizures in neonates with neonatal encephalopathy treated with hypothermia.
https://doi.org/10.1016/j.siny.2021.101279
Seminars in Fetal & Neonatal Medicine; DeLaGarza-Pineda O, Mailo JA et. al.

Sep 27th, 2021 - Neonatal encephalopathy (NE) is the most common etiology of acute neonatal seizures - about half of neonates treated with therapeutic hypothermia for NE have EEG-confirmed seizures. These seizures are best identified with continuous EEG monitoring...

Personalized treatment with retigabine for pharmacoresistant epilepsy arising from a pa...
https://doi.org/10.1684/epd.2021.1315
Epileptic Disorders : International Epilepsy Journal With... Nissenkorn A, Kornilov P et. al.

Sep 15th, 2021 - Mutations in the KCNQ2 gene, encoding the voltage-gated potassium channel, Kv7.2, cause neonatal epilepsies. The potassium channel opener, retigabine, may improve epilepsy control in cases with loss-of-function mutations, but exacerbate seizures i...

Family-Centered Care for Children and Families Impacted by Neonatal Seizures: Advice Fr...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523194
Pediatric Neurology; Lemmon ME, Glass HC et. al.

Sep 12th, 2021 - Parents of neonates with seizures are at risk of mental health symptoms due to the impact of illness on family life, prognostic uncertainty, and the emotional toll of hospitalization. A family-centered approach is the preferred model to mitigate t...

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Guidelines  1 results

ACR Appropriateness Criteria® Seizures-Child.
https://doi.org/10.1016/j.jacr.2021.02.020
Journal of the American College of Radiology : JACR; , Trofimova A et. al.

May 8th, 2021 - In children, seizures represent an extremely heterogeneous group of medical conditions ranging from benign cases, such as a simple febrile seizure, to life-threatening situations, such as status epilepticus. Underlying causes of seizures also repr...

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Clinicaltrials.gov  4 results

The Effect of AI-assisted cEEG Diagnosis on the Administration of Antiseizure Medication in Neonatal Seizures
https://clinicaltrials.gov/ct2/show/NCT05036395

Oct 12th, 2021 - The occurrence of neonatal seizures may be the first, and perhaps the only, clinical sign of a central nervous system disorder in the newborn infant. The promoted treatment of seizures can limit the secondary injury to the brain and positively aff...

Pharmacokinetic and Safety Trial of Intravenous Levetiracetam in the Treatment of Neonatal Seizures
https://clinicaltrials.gov/ct2/show/NCT00461409

Mar 26th, 2020 - In adults, drug clearance is less than half of the glomerular filtration rate and the drug half-life is 6-8 hours. Renal function in infants at birth is characterized by immature glomerular filtration and is only 20% that of older children. The sp...

Pharmacokinetic and Safety Trial of Intravenous Levetiracetam in the Treatment of Neonatal Seizures
https://clinicaltrials.gov/ct2/show/NCT00884052

Mar 26th, 2020 - In adults, drug clearance is less than half of the glomerular filtration rate and the drug half-life is 6-8 hours. Renal function in infants at birth is characterized by immature glomerular filtration and is only 20% that of older children. The sp...

Efficacy of Keppra for Neonatal Seizures
https://clinicaltrials.gov/ct2/show/NCT01475656

Apr 19th, 2013 - The purpose of this research study is to learn how well the medication levetiracetam (Keppra) works to treat seizures in full term and premature babies. Levetiracetam is commonly used in babies with seizures at Cincinnati Children's Hospital, espe...

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News  22 results

Stopping Seizure Meds Before Hospital Discharge Appears Safe in Most Newborns
https://www.medscape.com/viewarticle/952198

Jun 2nd, 2021 - NEW YORK (Reuters Health) - For most newborns with acute symptomatic seizures, doctors can safely stop antiseizure medications before hospital discharge, without worse neurodevelopmental outcomes or increased risk of epilepsy, a new study suggests...

Halting Antiseizure Medication Poses No Harm in Infants
https://www.medscape.com/viewarticle/939956

Oct 28th, 2020 - Maintaining antiseizure medication in infants who have had acute symptomatic neonatal seizures has been standard practice, but a prospective, observational, comparative effectiveness study calls that practice into question, providing evidence that...

Study supports halting antiseizure medications after neonatal seizures
https://www.mdedge.com/neurology/article/230768/epilepsy-seizures/study-supports-halting-antiseizure-medications-after
Richard Mark Kirkner

Oct 27th, 2020 - Maintaining antiseizure medication in infants who have had acute symptomatic neonatal seizures has been standard practice, but a prospective, observational, comparative effectiveness study calls that practice into question, providing evidence that.

Rapid Sequence MRI May Hold Advantages for Neonates With Seizures
https://www.mdedge.com/neurology/article/178954/pediatrics/rapid-sequence-mri-may-hold-advantages-neonates-seizures

Nov 5th, 2018 - CHICAGO—Use of rapid sequence MRI in the evaluation of neonates with seizures and no hypoxic-ischemic encephalopathy (HIE) is associated with reduced number of CT and MRI scans and similar length of hospital stay and cost, according to a study pre.

Promising add-on therapy for neonatal seizures found active in safety study
https://www.mdedge.com/neurology/article/153775/neurology/promising-add-therapy-neonatal-seizures-found-active-safety-study
Ted Bosworth

Dec 7th, 2017 - WASHINGTON – As a potential add-on therapy to phenobarbital, bumetanide demonstrated acceptable safety and promising antiseizure activity in a phase 1/2 safety study presented at the annual meeting of the American Epilepsy Society. “This is an ear.

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