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ALLMedicine Alpha1-antitrypsin Deficiency Center

Research & Reviews  135 results

Alpha1-Antitrypsin Deficiency.
https://doi.org/10.1056/NEJMra1910234
The New England Journal of Medicine; Strnad P, McElvaney NG et. al.

Apr 8th, 2020 - Alpha1-Antitrypsin Deficiency.|2020|Strnad P,McElvaney NG,Lomas DA,|drug therapy,etiology,physiopathology,etiology,physiopathology,therapeutic use,complications,diagnosis,genetics,therapy,

Molecular diagnosis of alpha1-antitrypsin deficiency: A new method based on Luminex tec...
https://doi.org/10.1002/jcla.23279
Journal of Clinical Laboratory Analysis REFERENCES; Ottaviani S, Barzon V et. al.

Mar 16th, 2020 - Alpha1-antitrypsin deficiency (AATD) is an under-diagnosed hereditary disorder characterized by reduced serum levels of alpha1-antitrypsin (AAT) and increased risk to develop lung and liver diseases at an early age. AAT is encoded by the highly po...

Alpha1-Antitrypsin (AAT) Deficiency
https://emedicine.medscape.com/article/295686-overview

Jul 25th, 2019 - Background Alpha1-antitrypsin deficiency (AATD, AAT deficiency) is an inherited condition that increases the risk of lung and liver disease. Alpha1-antitrypsin is a protein made by the liver whose function is to protect the lungs. If these protein...

Alpha1-Antitrypsin (AAT) Deficiency 
https://emedicine.medscape.com/article/295686-print

Jul 25th, 2019 - Background Alpha1-antitrypsin deficiency (AATD, AAT deficiency) is an inherited condition that increases the risk of lung and liver disease. Alpha1-antitrypsin is a protein made by the liver whose function is to protect the lungs. If these protein...

Liver disease related to alpha1-antitrypsin deficiency in French children: The DEFI-ALP...
https://doi.org/10.1111/liv.14035
Liver International : Official Journal of the International Association for the Study of the Liver; Ruiz M, Lacaille F et. al.

Dec 27th, 2018 - To identify prognostic factors for liver disease in children with alpha-1 antitrypsin deficiency, irrespective of phenotype, using the DEFI-ALPHA cohort. Retrospective, then prospective from 2010, multicentre study including children known to have...

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Guidelines  1 results

GLASSIA [Alpha-1 Proteinase Inhibitor (Human), Intravenous]
https://www.fda.gov/downloads/ApprovedProducts/UCM217890.pdf

GLASSIA is an alpha1-proteinase inhibitor that is indicated for chronic augmentation and maintenance therapy in adults with emphysema due to congenital deficiency of alpha1-proteinase inhibitor (Alpha1-PI), also known as alpha1-antitrypsin deficiency

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Drugs  4 results see all →

Clinicaltrials.gov  149 results

Alpha1-Antitrypsin Deficiency.
https://doi.org/10.1056/NEJMra1910234
The New England Journal of Medicine; Strnad P, McElvaney NG et. al.

Apr 8th, 2020 - Alpha1-Antitrypsin Deficiency.|2020|Strnad P,McElvaney NG,Lomas DA,|drug therapy,etiology,physiopathology,etiology,physiopathology,therapeutic use,complications,diagnosis,genetics,therapy,

Molecular diagnosis of alpha1-antitrypsin deficiency: A new method based on Luminex tec...
https://doi.org/10.1002/jcla.23279
Journal of Clinical Laboratory Analysis REFERENCES; Ottaviani S, Barzon V et. al.

Mar 16th, 2020 - Alpha1-antitrypsin deficiency (AATD) is an under-diagnosed hereditary disorder characterized by reduced serum levels of alpha1-antitrypsin (AAT) and increased risk to develop lung and liver diseases at an early age. AAT is encoded by the highly po...

Prolastin-c liquid - alpha1-proteinase inhibitor (human) injection, solution-GRIFOLS USA, LLC
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2b620e6b-6a24-0957-1288-ae529c4cc3a2

Jan 21st, 2020 - PROLASTIN-C LIQUID is an Alpha1-Proteinase Inhibitor (Human) (Alpha1-PI) indicated for chronic augmentation and maintenance therapy in adults with clinical evidence of emphysema due to severe hereditary deficiency of Alpha1-PI (alpha1-antitrypsin ...

Prolastin-c - alpha-1-proteinase inhibitor (human) kit-GRIFOLS USA, LLC
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=91edab72-c889-470e-8315-1798b5548dca

Jan 21st, 2020 - PROLASTIN-C is an Alpha1-Proteinase Inhibitor (Human) (Alpha1-PI) indicated for chronic augmentation and maintenance therapy in adults with clinical evidence of emphysema due to severe hereditary deficiency of Alpha1-PI (alpha1-antitrypsin deficie...

Alpha1-Antitrypsin (AAT) Deficiency
https://emedicine.medscape.com/article/295686-overview

Jul 25th, 2019 - Background Alpha1-antitrypsin deficiency (AATD, AAT deficiency) is an inherited condition that increases the risk of lung and liver disease. Alpha1-antitrypsin is a protein made by the liver whose function is to protect the lungs. If these protein...

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News  5 results

Alpha1-Antitrypsin Deficiency Significantly Increases Risk for Lung Cancer
https://www.medscape.com/viewarticle/575125

May 26th, 2008 - May 27, 2008 — Alpha1-antitrypsin deficiency (AATD) can greatly increase the risk for lung cancer, researchers report. AATD carriers might have a risk of developing lung cancer that is 70% higher than that for noncarriers, according to new data pu...

Influenza vaccination in subjects with alpha1-antitrypsin deficiency
https://www.medscape.com/viewarticle/576085

Abstract and Introduction Background: Influenza vaccination is recommended for all subjects with COPD, including α1-antitrypsin deficiency (AATD), but immunization practices are below US national goals. Influenza vaccination practices and their re...

GLASSIA [Alpha-1 Proteinase Inhibitor (Human), Intravenous]
https://www.fda.gov/downloads/ApprovedProducts/UCM217890.pdf

GLASSIA is an alpha1-proteinase inhibitor that is indicated for chronic augmentation and maintenance therapy in adults with emphysema due to congenital deficiency of alpha1-proteinase inhibitor (Alpha1-PI), also known as alpha1-antitrypsin deficiency

Should Health-Care Systems Pay for Replacement Therapy in Patients With Alpha1-Antitrypsin Deficiency? A Critical Review and Cost-Effectiveness Analysis
https://www.medscape.com/viewarticle/405946

Abstract and Introduction Study objectives: Assess cost effectiveness for providing alpha1-antitrypsin (alpha1-AT) replacement therapy to individuals with severe COPD and alpha1-AT deficiency. Materials and methods: The electronic databases MEDLIN...

Pharmacokinetic Comparability of Prolastin®-C to Prolastin® in Alpha1-antitrypsin Deficiency: A Randomized Study
https://www.medscape.com/viewarticle/730991

Abstract and Introduction Abstract Background: Alpha1-antitrypsin (AAT) deficiency is characterized by low blood levels of alpha1-proteinase inhibitor (alpha1-PI) and may lead to emphysema. Alpha1-PI protects pulmonary tissue from damage caused by...

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