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About 300 results

ALLMedicine™ Alpha1-antitrypsin Deficiency Center

Research & Reviews  141 results

Pulmonary Manifestations of Gastrointestinal, Pancreatic, and Liver Diseases in Children.
https://doi.org/10.1016/j.pcl.2020.09.002
Pediatric Clinics of North America; Le Fevre ER, McGrath KH et. al.

Nov 24th, 2020 - Pulmonary manifestations of gastrointestinal (GI) diseases are often subtle, and underlying disease may precede overt symptoms. A high index of suspicion and a low threshold for consultation with a pediatric pulmonologist is warranted in common GI...

Endo-phenotyping of COPD patients.
https://doi.org/10.1080/17476348.2020.1804364
Expert Review of Respiratory Medicine; Barnes PJ

Jul 30th, 2020 - Chronic obstructive pulmonary disease (COPD) is a heterogeneous syndrome and may comprise several different phenotypes that are driven by different molecular mechanisms (endotypes). Several different clinical, genetic, and inflammatory phenotypes ...

Alpha1-Antitrypsin Deficiency: A Cause of Chronic Liver Disease.
https://doi.org/10.1016/j.cld.2020.04.010
Clinics in Liver Disease; Manne V, Kowdley KV

Jul 5th, 2020 - Alpha1-antitrypsin deficiency (A1ATD) is an inherited cause of chronic liver disease. It is inherited in an autosomal codominant pattern with each inherited allele expressed in the formation of the final protein, which is primarily produced in hep...

Alpha1-Antitrypsin Deficiency.
https://doi.org/10.1056/NEJMra1910234
The New England Journal of Medicine; Strnad P, McElvaney NG et. al.

Apr 8th, 2020 - Alpha1-Antitrypsin Deficiency.|2020|Strnad P,McElvaney NG,Lomas DA,|drug therapy,etiology,physiopathology,etiology,physiopathology,therapeutic use,complications,diagnosis,genetics,therapy,

Molecular diagnosis of alpha1-antitrypsin deficiency: A new method based on Luminex tec...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370739
Journal of Clinical Laboratory Analysis REFERENCES; Ottaviani S, Barzon V et. al.

Mar 17th, 2020 - Alpha1-antitrypsin deficiency (AATD) is an under-diagnosed hereditary disorder characterized by reduced serum levels of alpha1-antitrypsin (AAT) and increased risk to develop lung and liver diseases at an early age. AAT is encoded by the highly po...

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Guidelines  1 results

GLASSIA [Alpha-1 Proteinase Inhibitor (Human), Intravenous]
https://www.fda.gov/downloads/ApprovedProducts/UCM217890.pdf

GLASSIA is an alpha1-proteinase inhibitor that is indicated for chronic augmentation and maintenance therapy in adults with emphysema due to congenital deficiency of alpha1-proteinase inhibitor (Alpha1-PI), also known as alpha1-antitrypsin deficiency

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Drugs  4 results see all →

Clinicaltrials.gov  151 results

Pulmonary Manifestations of Gastrointestinal, Pancreatic, and Liver Diseases in Children.
https://doi.org/10.1016/j.pcl.2020.09.002
Pediatric Clinics of North America; Le Fevre ER, McGrath KH et. al.

Nov 24th, 2020 - Pulmonary manifestations of gastrointestinal (GI) diseases are often subtle, and underlying disease may precede overt symptoms. A high index of suspicion and a low threshold for consultation with a pediatric pulmonologist is warranted in common GI...

Endo-phenotyping of COPD patients.
https://doi.org/10.1080/17476348.2020.1804364
Expert Review of Respiratory Medicine; Barnes PJ

Jul 30th, 2020 - Chronic obstructive pulmonary disease (COPD) is a heterogeneous syndrome and may comprise several different phenotypes that are driven by different molecular mechanisms (endotypes). Several different clinical, genetic, and inflammatory phenotypes ...

Alpha1-Antitrypsin Deficiency: A Cause of Chronic Liver Disease.
https://doi.org/10.1016/j.cld.2020.04.010
Clinics in Liver Disease; Manne V, Kowdley KV

Jul 5th, 2020 - Alpha1-antitrypsin deficiency (A1ATD) is an inherited cause of chronic liver disease. It is inherited in an autosomal codominant pattern with each inherited allele expressed in the formation of the final protein, which is primarily produced in hep...

Alpha1-Antitrypsin Deficiency.
https://doi.org/10.1056/NEJMra1910234
The New England Journal of Medicine; Strnad P, McElvaney NG et. al.

Apr 8th, 2020 - Alpha1-Antitrypsin Deficiency.|2020|Strnad P,McElvaney NG,Lomas DA,|drug therapy,etiology,physiopathology,etiology,physiopathology,therapeutic use,complications,diagnosis,genetics,therapy,

Molecular diagnosis of alpha1-antitrypsin deficiency: A new method based on Luminex tec...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370739
Journal of Clinical Laboratory Analysis REFERENCES; Ottaviani S, Barzon V et. al.

Mar 17th, 2020 - Alpha1-antitrypsin deficiency (AATD) is an under-diagnosed hereditary disorder characterized by reduced serum levels of alpha1-antitrypsin (AAT) and increased risk to develop lung and liver diseases at an early age. AAT is encoded by the highly po...

see more →

News  3 results

Alpha1-Antitrypsin Deficiency Significantly Increases Risk for Lung Cancer
https://www.medscape.com/viewarticle/575125

May 26th, 2008 - May 27, 2008 — Alpha1-antitrypsin deficiency (AATD) can greatly increase the risk for lung cancer, researchers report. AATD carriers might have a risk of developing lung cancer that is 70% higher than that for noncarriers, according to new data pu...

Alpha1-Antitrypsin Deficiency Significantly Increases Risk for Lung Cancer
https://www.staging.medscape.com/viewarticle/575125

May 26th, 2008 - May 27, 2008 — Alpha1-antitrypsin deficiency (AATD) can greatly increase the risk for lung cancer, researchers report. AATD carriers might have a risk of developing lung cancer that is 70% higher than that for noncarriers, according to new data pu...

GLASSIA [Alpha-1 Proteinase Inhibitor (Human), Intravenous]
https://www.fda.gov/downloads/ApprovedProducts/UCM217890.pdf

GLASSIA is an alpha1-proteinase inhibitor that is indicated for chronic augmentation and maintenance therapy in adults with emphysema due to congenital deficiency of alpha1-proteinase inhibitor (Alpha1-PI), also known as alpha1-antitrypsin deficiency

see more →