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About 40,125 results

ALLMedicine™ Chronic Obstructive Pulmonary Disease Center

Research & Reviews  13,616 results

Serum MCP-1 and NGAL Play an Important Role in the Acute Inflammatory Event of Chronic ...
https://doi.org/10.1080/15412555.2021.1954151
COPD Chen XR, Wang DX

Jul 31st, 2021 - NGAL is mainly secreted by neutrophils which play the core role in AECOPD. MCP-1 is secreted specifically by monocytes and macrophages. Both biomarkers are involved in the core process of acute inflammatory reaction in COPD. So We analyzed serum N...

Relationship between Air Pollution and Hospital Admissions for Chronic Obstructive Pulm...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302390
Canadian Respiratory Journal; Ju Y, Ma X et. al.

Jul 31st, 2021 - This study aimed to explore the relationship between air pollution and hospital admissions for COPD in Changchun, a northeast city of China, in different seasons. The data on a total of 1,733 hospitalized patients living in Changchun with acute ex...

Challenges in the Implementation of Chronic Obstructive Pulmonary Disease Guidelines in...
https://doi.org/10.1513/AnnalsATS.202103-284ST
Annals of the American Thoracic Society; Hurst JR, Buist AS et. al.

Jul 31st, 2021 - There is a substantial burden of chronic respiratory diseases, including chronic obstructive pulmonary disease (COPD), in low- and middle-income countries (LMICs). LMICs have particular challenges in delivering cost-effective prevention, diagnosis...

Risk of all-cause mortality associated with chronic obstructive pulmonary disease and t...
https://doi.org/10.1136/bmjopen-2021-050947
BMJ Open; Bayes-Marin I, Sanchez-Niubo A et. al.

Jul 30th, 2021 - The aims were to study the risk of all-cause mortality associated with chronic obstructive pulmonary disease (COPD) and healthy ageing trajectories (HAT) in three birth cohorts and to determine the moderating role of HAT in the association between...

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Guidelines  18 results

Long-Term Mechanical Ventilation: Recommendations of the Swiss Society of Pulmonology.
https://doi.org/10.1159/000510086
Respiration; International Review of Thoracic Diseases; Janssens JP, Michel F et. al.

Dec 11th, 2020 - Long-term mechanical ventilation is a well-established treatment for chronic hypercapnic respiratory failure (CHRF). It is aimed at improving CHRF-related symptoms, health-related quality of life, survival, and decreasing hospital admissions. In S...

Long-Term Noninvasive Ventilation in Chronic Stable Hypercapnic Chronic Obstructive Pul...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427384
American Journal of Respiratory and Critical Care Medicine; Macrea M, Oczkowski S et. al.

Aug 17th, 2020 - Background: Noninvasive ventilation (NIV) is used for patients with chronic obstructive pulmonary disease (COPD) and chronic hypercapnia. However, evidence for clinical efficacy and optimal management of therapy is limited.Target Audience: Patient...

Adult Patients with Respiratory Distress: Current Evidence-based Recommendations for Pr...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390576
The Western Journal of Emergency Medicine; Hodroge SS, Glenn M et. al.

Jul 30th, 2020 - We developed evidence-based recommendations for prehospital evaluation and treatment of adult patients with respiratory distress. These recommendations are compared with current protocols used by the 33 local emergency medical services agencies (L...

ACR Appropriateness Criteria® Chronic Dyspnea-Noncardiovascular Origin.
https://doi.org/10.1016/j.jacr.2018.09.015
Journal of the American College of Radiology : JACR; , McComb BL et. al.

Nov 6th, 2018 - Chronic dyspnea may result from a variety of disorders of cardiovascular, pulmonary, gastrointestinal, neuromuscular, systemic, and psychogenic etiology. This article discusses guidelines for the initial imaging of six variants for chronic dyspnea...

Diagnosis, Prevention and Treatment of Stable COPD and Acute Exacerbations of COPD: The...
https://doi.org/10.1159/000490551
Respiration; International Review of Thoracic Diseases; Stolz D, Barandun J et. al.

Aug 24th, 2018 - The Swiss National Guidelines 2013 for chronic obstructive pulmonary disease have been revised in order to acknowledge recent progress in diagnosis and management of this disease. The resulting new Swiss recommendations are based on best evidence ...

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Drugs  127 results see all →

Clinicaltrials.gov  1,010 results

Pathophysiology of the Upper Airway in Patients With COPD and Concomitant OSA
https://clinicaltrials.gov/ct2/show/NCT02567448

May 7th, 2020 - This is a physiologic study to assess the effects of lower airway and lung tissue changes of COPD on upper airway collapsibility. Increased in lung volume and destruction of alveolar wall in COPD may have opposite and various effects on the upper ...

Role of Genetic Factors in the Development of Lung Disease
https://clinicaltrials.gov/ct2/show/NCT00001532

May 4th, 2020 - This study is designed to evaluate genetic mechanisms of lung disease by surveying polymorphic genes involved in respiratory function and examining gene expression in the lung cells of individuals with pulmonary disease (e.g., alpha 1-antitrypsin ...

Long-term Observational Study of the Safety of Roflumilast
https://clinicaltrials.gov/ct2/show/NCT03381573

Apr 29th, 2020 - Rationale and background Roflumilast is licensed (i) for maintenance treatment of severe chronic obstructive pulmonary disease (COPD) (FEV1 post-bronchodilator less than 50% predicted) associated with chronic bronchitis (CB) in adult patients with...

A Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics (PK) of Nemiralisib
https://clinicaltrials.gov/ct2/show/NCT03398421

Apr 27th, 2020 - Nemiralisib is a potent anti-inflammatory agent for the treatment of chronic obstructive pulmonary disease (COPD) and other inflammatory lung diseases. The Cytochrome P450 3A4 (CYP3A4) is a major route of clearance for nemiralisib. The co-administ...

Pulmonary Specialist-Health Coach Consult Model Study
https://clinicaltrials.gov/ct2/show/NCT03695276

Apr 24th, 2020 - While evidence-based care for chronic obstructive pulmonary disease (COPD) and asthma can substantially reduce disease burden and prevent emergency visits and hospitalizations, it is estimated that 55% of patients with COPD do not receive all reco...

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News  1,263 results

Patients With Moderate COPD Also Benefit From Triple Therapy
https://www.medscape.com/viewarticle/951823

May 25th, 2021 - The benefits of a triple fixed-dose inhaled corticosteroid, long-acting muscarinic antagonist, and long-acting beta2 agonist combination extend to patients with moderate as well as severe chronic obstructive pulmonary disease (COPD). That's accord...

COPD in Younger Adults Deadlier Than Expected
https://www.medscape.com/viewarticle/951826

May 25th, 2021 - Adults in their 30s, 40s and 50s with chronic obstructive pulmonary disease (COPD) experience significant morbidity and excess mortality from the disease, results of a population-based study show. Among adults aged 35-55 years with COPD in Ontario...

Sex Differences in COPD Symptoms Predict Cardiac Comorbidity
https://www.medscape.com/viewarticle/951460

May 19th, 2021 - Sex-specific differences in the severity of symptoms and prevalence of comorbidities in patients with chronic obstructive pulmonary disease (COPD) may point to different criteria for diagnosing cardiac comorbidities in women and men, a retrospecti...

Worse Outcomes for Patients With COPD and COVID-19
https://www.medscape.com/viewarticle/951356

May 18th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. A study of COVID-19 outcomes across the United States bolsters reports from China and Europe that indicate that patients with chronic obstructive ...

Unhealthy Sleep Behaviours May Increase the Risk of Shortened Healthspan
https://www.medscape.com/viewarticle/951000

May 12th, 2021 - A new prospective cohort study published in the journal  Sleep and Breathing suggests that certain unhealthy sleep behaviours are associated with a higher risk of shortened healthspan. Researchers determined the associations between four sleep beh...

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Patient Education  16 results see all →