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About 7,623 results

ALLMedicine™ Idiopathic Pulmonary Fibrosis Center

Research & Reviews  2,685 results

Regulation of the IGF1 signaling pathway is involved in idiopathic pulmonary fibrosis i...
https://doi.org/10.18632/aging.203335
Aging Sun W, Jing X et. al.

Jul 31st, 2021 - Idiopathic pulmonary fibrosis (IPF) mainly occurs in elderly people over the age of sixty. IPF pathogenesis is associated with alveolar epithelial cells (AECs) senescence. Activation of PI3K/AKT signaling induced by insulin-like growth factor 1 (I...

Pulmonary fibrosis distal airway epithelia are dynamically and structurally dysfunctional.
https://doi.org/10.1038/s41467-021-24853-8 10.1513/pats.200805-041HR 10.1242/dmm.006031 10.2147/JIR.S280958 10.1016/j.stem.2020.03.009 10.1046/j.1440-1843.2003.00493.x 10.1513/pats.200907-072DP 10.1183/09031936.00141514 10.1073/pnas.1504102112 10.1038/ncomms4923 10.1242/dev.143784 10.1513/AnnalsATS.201802-128AW 10.1371/journal.pone.0018378 10.1073/pnas.1710196114 10.1016/j.stem.2015.01.002 10.1016/j.cub.2012.09.046 10.1056/NEJMra1705751 10.1513/AnnalsATS.201410-448MG 10.1172/JCI60323 10.1016/j.bbadis.2013.03.001 10.1056/NEJMoa1013660 10.1126/sciadv.aba1983 10.1126/sciadv.aba1972 10.1152/physrev.00004.2016 10.1371/journal.pone.0058658 10.1016/S2213-2600(19)30356-X 10.1038/s41467-021-23277-8 10.1038/s41467-018-07768-9 10.1038/embor.2012.149 10.1098/rstb.2019.0387 10.1038/s41467-020-18841-7 10.1038/s41586-018-0479-2 10.1038/s41563-019-0425-1 10.1038/nmat4848 10.1038/nmat4357 10.1038/nphys3471 10.1186/s12931-016-0404-x 10.1038/s41598-020-57755-8 10.1172/jci.insight.90558 10.1093/jmcb/mju046 10.1016/j.cell.2017.09.017 10.1038/s41467-019-10729-5 10.1016/j.cell.2016.06.028 10.1242/dev.139071 10.1016/j.cell.2009.11.007 10.1038/ncb1993 10.1073/pnas.1216462110 10.1038/s41419-018-0302-x 10.15252/emmm.201404976 10.1164/rccm.201509-1872LE 10.1038/s41598-020-74992-z 10.1038/s41586-020-1998-1 10.1002/cam4.416 10.1038/ni.3709 10.1164/rccm.201810-1972OC 10.1152/ajplung.00415.2017 10.1152/ajplung.00300.2014 10.1074/jbc.M112.356824 10.1073/pnas.111133298 10.5334/jors.bl 10.1002/cyto.a.22034 10.1038/nbt.3519 10.1186/s13059-014-0550-8 10.1186/1471-2105-14-128 10.1093/nar/gkw377 10.1093/nar/gku443 10.1002/adbi.201900022 10.1111/j.1749-6632.1990.tb24251.x 10.1122/1.551012
Nature Communications; Stancil IT, Michalski JE et. al.

Jul 29th, 2021 - The airway epithelium serves as the interface between the host and external environment. In many chronic lung diseases, the airway is the site of substantial remodeling after injury. While, idiopathic pulmonary fibrosis (IPF) has traditionally bee...

Epidemiology of Idiopathic Pulmonary Fibrosis Among U.S. Veterans, 2010 - 2019.
https://doi.org/10.1513/AnnalsATS.202103-295OC
Annals of the American Thoracic Society; Kaul B, Lee JS et. al.

Jul 28th, 2021 - The development of novel therapies for idiopathic pulmonary fibrosis (IPF) has brought increased attention to the population burden of disease. However, little is known about the epidemiology of IPF among United States Veterans. This study examine...

Hyperpolarized 129Xe MRI and Spectroscopy of Gas-Exchange Abnormalities in Nonspecific ...
https://doi.org/10.1148/radiol.2021204149
Radiology Mummy DG, Bier EA et. al.

Jul 28th, 2021 - Background Recent studies demonstrate that antifibrotic drugs previously reserved for idiopathic pulmonary fibrosis (IPF) may slow progression in other interstitial lung diseases (ILDs), creating an urgent need for tools that can sensitively asses...

Associations between Diabetes and Idiopathic Pulmonary Fibrosis: A Study-level Pooled a...
https://doi.org/10.1210/clinem/dgab553
The Journal of Clinical Endocrinology and Metabolism; Li C, Xiao Y et. al.

Jul 25th, 2021 - Diabetes mellitus (DM) is a systemic disease characterized by chronic hyperglycemia associated with inflammation and oxidative stress, and the lung may be a target organ of diabetic microvascular damage. Several studies have indicated a positive a...

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Guidelines  4 results

S2K Guideline for Diagnosis of Idiopathic Pulmonary Fibrosis.
https://doi.org/10.1159/000512315
Respiration; International Review of Thoracic Diseases; Behr J, Günther A et. al.

Jan 25th, 2021 - Idiopathic pulmonary fibrosis (IPF) is a severe and often fatal disease. Diagnosis of IPF requires considerable expertise and experience. Since the publication of the international IPF guideline in the year 2011 and the update 2018 several studies...

Guidelines of the Polish Respiratory Society for diagnosis and treatment of idiopathic ...
https://doi.org/10.5603/ARM.2020.0081
Advances in Respiratory Medicine; Piotrowski WJ, Bestry I et. al.

Mar 11th, 2020 - This document presents the guidelines of the Polish Respiratory Society (PTChP, Polskie Towarzystwo Chorób Płuc) for diagnosis and treatment of idiopathic pulmonary fibrosis (IPF), developed by agroup of Polish experts. The recommendations were de...

An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline: Treatment of Idiopathic Pulmo...
https://doi.org/10.1164/rccm.201506-1063ST
American Journal of Respiratory and Critical Care Medicine; Raghu G, Rochwerg B et. al.

Jul 16th, 2015 - This document updates the American Thoracic Society/European Respiratory Society/Japanese Respiratory Society/Latin American Thoracic Association guideline on idiopathic pulmonary fibrosis treatment. Systematic reviews and, when appropriate, meta-...

An official American Thoracic Society/European Respiratory Society statement: Update of...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803655
American Journal of Respiratory and Critical Care Medicine; Travis WD, Costabel U et. al.

Sep 17th, 2013 - In 2002 the American Thoracic Society/European Respiratory Society (ATS/ERS) classification of idiopathic interstitial pneumonias (IIPs) defined seven specific entities, and provided standardized terminology and diagnostic criteria. In addition, t...

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Drugs  13 results see all →

Clinicaltrials.gov  147 results

Investigating Trends in Quality of Life in Patients With Idiopathic Pulmonary Fibrosis (IPF) Under Treatment With Nintedanib
https://clinicaltrials.gov/ct2/show/NCT03710824

May 7th, 2020 - Multi-center, non-interventional, prospective cohort study aiming to enroll 240 Idiopathic Pulmonary Fibrosis patients receiving treatment with nintedanib in a consecutive manner from 10-12 reference centers across Greece.

Study of Pulmonary Rehabilitation in Patients With Idiopathic Pulmonary Fibrosis (IPF)
https://clinicaltrials.gov/ct2/show/NCT03717012

May 5th, 2020 - The main objectives of this study are: Determine the difference in change from baseline in Six Minute Walk Distance (6MWD) when pulmonary rehabilitation (PR) is added to stable underlying nintedanib therapy in patients with idiopathic pulmonary fi...

A Pilot Study of Aerosol Interferon-gamma for Treatment of Idiopathic Pulmonary Fibrosis
https://clinicaltrials.gov/ct2/show/NCT00563212

Apr 28th, 2020 - Patients with mild-to-moderate idiopathic pulmonary fibrosis (IPF) will be enrolled in a phase I study of aerosol interferon-gamma (IFN-γ). Prior to initiation of treatment, patients will undergo CT of the chest, pulmonary function testing, and br...

Using MRI to Visualize Regional Therapy Response in Idiopathic Pulmonary Fibrosis
https://clinicaltrials.gov/ct2/show/NCT02478268

Apr 27th, 2020 - The purpose of this study is to determine whether magnetic resonance imaging (MRI) using inhaled hyperpolarized 129Xe gas, and conventional contrast can help visualize impaired lung function and detect changes over time in patients receiving treat...

Non-Interventional Study (NIS) Collecting Experiences For IPF in Taiwan
https://clinicaltrials.gov/ct2/show/NCT03242759

Apr 21st, 2020 - This is a non-interventional, multi-center study to collect data from patients with idiopathic pulmonary fibrosis (IPF) in clinical practice in Taiwan. The study will be carried out at 10 medical centers, the expert centers where IPF patients are ...

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News  197 results

Fast Five Quiz: Diagnosing Idiopathic Pulmonary Fibrosis
https://reference.medscape.com/viewarticle/909154

Feb 4th, 2021 - Idiopathic pulmonary fibrosis (IPF) is the most common form of chronic, progressive fibrosing interstitial pneumonia of unknown origin. The histopathology and radiological findings of IPF are the same as those of usual interstitial pneumonia (UIP)...

PPI Use Not Associated With Improved Survival in Idiopathic Pulmonary Fibrosis
https://www.medscape.com/viewarticle/936990

Sep 8th, 2020 - Takeaway In patients with idiopathic pulmonary fibrosis (IPF), the use of proton pump inhibitors (PPIs) is not associated with improved survival and reduced incidence of respiratory-related hospitalisation compared with non-use. Why this matters F...

PPI Use Not Associated With Improved Survival in Idiopathic Pulmonary Fibrosis
https://www.staging.medscape.com/viewarticle/936990

Sep 8th, 2020 - Takeaway In patients with idiopathic pulmonary fibrosis (IPF), the use of proton pump inhibitors (PPIs) is not associated with improved survival and reduced incidence of respiratory-related hospitalisation compared with non-use. Why this matters F...

Fast Five Quiz: Idiopathic Pulmonary Fibrosis Comorbidities and Complications
https://reference.medscape.com/viewarticle/925460_5

Jul 13th, 2020 - An increased prevalence of both OSA and GERD has been noted in patients with IPF. However, OSA has not been found to be a risk factor for GERD among patients with IPF. The use of GERD medications has been associated with longer survival times and ...

Fast Five Quiz: Idiopathic Pulmonary Fibrosis Comorbidities and Complications
https://reference.medscape.com/viewarticle/925460_6

Jul 13th, 2020 - Approximately 30% of patients with IPF have comorbid emphysema. The presence of comorbid emphysema does not disqualify patients with IPF for consideration or evaluation for lung transplantation. Comorbid emphysema is more commonly seen in men with...

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Patient Education  3 results see all →