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About 10,615 results

ALLMedicine™ Pulmonary Fibrosis Center

Research & Reviews  3,973 results

Improved Prognostic Prediction by Combination of Early Initiation of Polymyxin B Hemope...
https://doi.org/10.1159/000518705
Blood Purification; Oishi K, Azuma A et. al.

Sep 15th, 2021 - Respiratory failure from acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) is associated with high mortality. Direct hemoperfusion with polymyxin B-immobilized fiber column (PMX-DHP) has been reported to have beneficial effects on patie...

COVID-19-associated acute respiratory distress syndrome (CARDS): Current knowledge on p...
https://doi.org/10.1016/j.bpa.2020.12.011
Best Practice & Research. Clinical Anaesthesiology; Pfortmueller CA, Spinetti T et. al.

Sep 14th, 2021 - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces coronavirus-19 disease (COVID-19) and is a major health concern. Following two SARS-CoV-2 pandemic "waves," intensive care unit (ICU) specialists are treating a large number of C...

Impact of Gender on the Characteristics of Patients with Idiopathic Pulmonary Fibrosis ...
https://doi.org/10.1159/000518008
Respiration; International Review of Thoracic Diseases; Cottin V, Gueguen S et. al.

Sep 14th, 2021 - There is growing evidence of gender-specific phenotypic differences among patients with idiopathic pulmonary fibrosis (IPF), which may affect patient outcomes. We present the characteristics of patients with IPF at inclusion in the French Rare Dis...

Patient Activation for Self-Management in Patients with Idiopathic Pulmonary Fibrosis o...
https://doi.org/10.1159/000518216
Respiration; International Review of Thoracic Diseases; Bloem AEM, Mostard RLM et. al.

Sep 14th, 2021 - Self-management is considered important in the management of patients with idiopathic pulmonary fibrosis (IPF) or sarcoidosis. However, data about the degree of activation for self-management is lacking. The aim of the study was to determine the d...

DSP rs2076295 variants influence nintedanib and pirfenidone outcomes in idiopathic pulm...
https://doi.org/10.1177/17534666211042529
Therapeutic Advances in Respiratory Disease; Doubkova M, Kriegova E et. al.

Sep 14th, 2021 - The antifibrotic drugs nintedanib and pirfenidone are used for the treatment of idiopathic pulmonary fibrosis (IPF). We analysed the association of common profibrotic polymorphisms in MUC5B (mucin 5B, rs35705950) and DSP (desmoplakin, rs2076295) o...

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Guidelines  4 results

S2K Guideline for Diagnosis of Idiopathic Pulmonary Fibrosis.
https://doi.org/10.1159/000512315
Respiration; International Review of Thoracic Diseases; Behr J, Günther A et. al.

Jan 25th, 2021 - Idiopathic pulmonary fibrosis (IPF) is a severe and often fatal disease. Diagnosis of IPF requires considerable expertise and experience. Since the publication of the international IPF guideline in the year 2011 and the update 2018 several studies...

Guidelines of the Polish Respiratory Society for diagnosis and treatment of idiopathic ...
https://doi.org/10.5603/ARM.2020.0081
Advances in Respiratory Medicine; Piotrowski WJ, Bestry I et. al.

Mar 11th, 2020 - This document presents the guidelines of the Polish Respiratory Society (PTChP, Polskie Towarzystwo Chorób Płuc) for diagnosis and treatment of idiopathic pulmonary fibrosis (IPF), developed by agroup of Polish experts. The recommendations were de...

An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline: Treatment of Idiopathic Pulmo...
https://doi.org/10.1164/rccm.201506-1063ST
American Journal of Respiratory and Critical Care Medicine; Raghu G, Rochwerg B et. al.

Jul 16th, 2015 - This document updates the American Thoracic Society/European Respiratory Society/Japanese Respiratory Society/Latin American Thoracic Association guideline on idiopathic pulmonary fibrosis treatment. Systematic reviews and, when appropriate, meta-...

An official American Thoracic Society/European Respiratory Society statement: Update of...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803655
American Journal of Respiratory and Critical Care Medicine; Travis WD, Costabel U et. al.

Sep 17th, 2013 - In 2002 the American Thoracic Society/European Respiratory Society (ATS/ERS) classification of idiopathic interstitial pneumonias (IIPs) defined seven specific entities, and provided standardized terminology and diagnostic criteria. In addition, t...

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Drugs  20 results see all →

Clinicaltrials.gov  8 results

Inhaled ZYESAMI™ (Aviptadil Acetate) for the Treatment of Severe COVID-19
https://clinicaltrials.gov/ct2/show/NCT04360096

Sep 8th, 2021 - Detailed Description: Attack of the Alveolar Type II (ATII) cell via its ACE2 surface receptor by the SARS-CoV-2 virus leads to respiratory failure, morbidity, and frequently mortality in COVID-19. There is no approved treatment that specifically ...

Evaluation of Efficacy and Safety of PLN-74809 in Patients With Idiopathic Pulmonary Fibrosis
https://clinicaltrials.gov/ct2/show/NCT04396756

Aug 18th, 2021 - Three part study: Part A - 4 week treatment period evaluating PLN-74809 or matching placebo Part B - 12 week treatment period evaluating PLN-74809 or matching placebo Part C - 12 week treatment period evaluating up to two higher PLN-74809 dose coh...

Hyperbaric Oxygen Therapy Effect in COVID-19 RCT (HBOTCOVID19)
https://clinicaltrials.gov/ct2/show/NCT04358926

Feb 3rd, 2021 - The 2019-20 coronavirus disease, caused by COVID-19, is an ongoing pandemic. The outbreak started in Wuhan, Hubei province, China, in December 2019 and the World Health Organization (WHO) recognized it as a pandemic on 11 March 2020. Up to Apr 9. ...

Molecular Imaging Probes to Inform Heterogeneity in Idiopathic Pulmonary Fibrosis
https://clinicaltrials.gov/ct2/show/NCT04362644

Jan 6th, 2021 - The purpose of the study is to see if imaging with [18F]FDG and [18F]DPA-714 using positron emission tomography and computed tomography (PET/CT) will show lung inflammation and fibrosis in patients diagnosed with idiopathic pulmonary fibrosis (IPF...

Safety, Tolerability, and Efficacy Study of Idiopathic Pulmonary Fibrosis
https://clinicaltrials.gov/ct2/show/NCT01262001

Oct 9th, 2019 - Major Changes: FGCL-3019-049 Protocol Amendment 3 offers long-term extension of treatment with FG-3019 to eligible Cohort 1-EX (approximately 14 subjects) and Cohort 2 (approximately 28 subjects) subjects who complete the Week 48-EX and Week 48 as...

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News  239 results

Treatment Sequencing for HER2-Positive Metastatic Breast Cancer
https://www.onclive.com/view/treatment-sequencing-for-her2-positive-metastatic-breast-cancer

Jul 15th, 2021 - Sara A. Hurvitz, MD: When deciding how to sequence therapies, we don’t have clear guidance based on evidence. From a practical standpoint, if I have a patient in my clinic whose disease has progressed after T-DM1, or trastuzumab emtansine-based th...

Fast Five Quiz: Diagnosing Idiopathic Pulmonary Fibrosis
https://reference.medscape.com/viewarticle/909154

Feb 4th, 2021 - Idiopathic pulmonary fibrosis (IPF) is the most common form of chronic, progressive fibrosing interstitial pneumonia of unknown origin. The histopathology and radiological findings of IPF are the same as those of usual interstitial pneumonia (UIP)...

Race Adjustments for Spirometers Could Exacerbate Racial Disparities in COVID Recovery
https://www.medscape.com/viewarticle/942927

Dec 21st, 2020 - NEW YORK (Reuters Health) - Racial biases built into spirometers have the potential to exacerbate racial disparities in recovery from COVID-19, caution the authors of a comment in The Lancet Respiratory Medicine. Minority populations suffer dispro...

Radiation Avoidable in Some Wilms Tumor Patients With Lung Metastases
https://www.onclive.com/view/radiation-avoidable-in-some-wilms-tumor-patients-with-lung-metastases

Dec 4th, 2020 - Jeffrey S. Dome, MD, PhD A novel risk stratification and treatment approach led to enhanced clinical outcomes overall, as well as the successful omission of radiotherapy (RT) for some patients with stage IV favorable histology Wilms tumor and pul...

PPI Use Not Associated With Improved Survival in Idiopathic Pulmonary Fibrosis
https://www.medscape.com/viewarticle/936990

Sep 8th, 2020 - Takeaway In patients with idiopathic pulmonary fibrosis (IPF), the use of proton pump inhibitors (PPIs) is not associated with improved survival and reduced incidence of respiratory-related hospitalisation compared with non-use. Why this matters F...

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Patient Education  2 results see all →