ALLMedicine™ Sarcoidosis Center

Jun 26th, 2022 - To identify multidimensional phenotypes of sarcoid uveitis patients Design: Retrospective cohort. Study Population: Consecutive patients with biopsy-proven, presumed or probable sarcoid uveitis between December 2003 and December 2020 in Lyon. Data...

Jun 25th, 2022 - This review aims to describe how the clinical manifestations of sarcoidosis may be shaped by the effects of sex hormones and by age dependent changes in immune functions and physiology This review is intended to highlight the need to consider the ...

Jun 25th, 2022 - Ageing, the accrual of molecular and cellular damage over a lifetime confers progressive physiologic dysfunction of bodily systems, leaving the body in a heightened state of vulnerability to biophysical and psychosocial stressors. The inflection p...

Jun 24th, 2022 - Uveitis refers to a large group of intraocular inflammatory diseases that can cause devastating visual loss in adults and children. This study establishes a clinical database and biospecimen repository for the identification of novel factors relev...

Jun 24th, 2022 - This study will be a prospective, longitudinal, observational, single-center, exploratory, natural history study to collect samples and data that will enable prospective explorations of the interaction between environmental exposures and disease p...

Jun 19th, 2021 - The major reasons to treat sarcoidosis are to lower the morbidity and mortality risk or to improve quality of life (QoL). The indication for treatment varies depending on which manifestation is the cause of symptoms: lungs, heart, brain, skin or o...

Apr 16th, 2020 - Background: The diagnosis of sarcoidosis is not standardized but is based on three major criteria: a compatible clinical presentation, finding nonnecrotizing granulomatous inflammation in one or more tissue samples, and the exclusion of alternativ...

May 13th, 2019 - Arrhythmogenic cardiomyopathy (ACM) is an arrhythmogenic disorder of the myocardium not secondary to ischemic, hypertensive, or valvular heart disease. ACM incorporates a broad spectrum of genetic, systemic, infectious, and inflammatory disorders....

Jun 9th, 2015 - Inflammatory diseases of the aorta include routine atherosclerosis, aortitis, periaortitis, and atherosclerosis with excessive inflammatory responses, such as inflammatory atherosclerotic aneurysms. The nomenclature and histologic features of thes...

Jun 24th, 2022 - Uveitis refers to a large group of intraocular inflammatory diseases that can cause devastating visual loss in adults and children. This study establishes a clinical database and biospecimen repository for the identification of novel factors relev...

Jun 24th, 2022 - This study will be a prospective, longitudinal, observational, single-center, exploratory, natural history study to collect samples and data that will enable prospective explorations of the interaction between environmental exposures and disease p...

Jun 24th, 2022 - This study is designed to evaluate genetic mechanisms of lung disease by surveying polymorphic genes involved in respiratory function and examining gene expression in the lung cells of individuals with pulmonary disease (e.g., alpha 1-antitrypsin ...

Jun 23rd, 2022 - About 20% of individuals with Corona Virus disease (COVID-19) experience more severe disease characterized by significant respiratory symptoms including acute respiratory distress syndrome (ARDS). ARDS is a known lethal complication due to its low...

Jun 23rd, 2022 - Macrophages are phagocytic cells of the innate immune system. Their accumulation is a hallmark of many inflammatory diseases and they have diverse roles in tissue responses to infection and injury and in tissue repair. As macrophages have a tissue...

Jun 22nd, 2022 - The Diagnosis: Granuloma Annulare A biopsy of a lesion on the right flank demonstrated granulomatous inflammation and interstitial mucin (Figure), characteristic of granuloma annulare (GA). 1,2 Granuloma annulare is a relatively common skin disord.

Jun 13th, 2022 - Finger injuries are often seen in the primary care physician’s office. The evidence—and our experience in sports medicine—indicates that many of these injuries can be managed conservatively with bracing or injection; a subset, however, requires su.

May 24th, 2022 - Sarcoidosis is often treated with high-dose oral corticosteroids for extended periods of time. Anytime we prescribe oral corticosteroids, my fellow always wants to start trimethoprim-sulfamethoxazole (TMP-SMX) prophylaxis against Pneumocystis jiro...

May 12th, 2022 - A 4-mm punch biopsy of the annular border confirmed a diagnosis of localized granuloma annulare (GA). There is a long list of differential diagnoses for annular patches and plaques; it includes tinea corporis and important systemic diseases such a.

Apr 26th, 2022 - To the Editor: A 53-year-old Hispanic woman presented to our dermatology clinic for evaluation of an expanding plaque on the right cheek of 2 months’ duration. The patient stated the plaque began as a pimple, which she picked with subsequent sprea.