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About 462 results

ALLMedicine Acetaminophen Toxicity Center

Research & Reviews  201 results

Cell-permeable succinate prodrugs rescue mitochondrial respiration in cellular models o...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135280
PloS One; Piel S, Chamkha I et. al.

Apr 6th, 2020 - Acetaminophen is one of the most common over-the-counter pain medications used worldwide and is considered safe at therapeutic dose. However, intentional and unintentional overdose accounts for up to 70% of acute liver failure cases in the western...

Suppression of glomerular damage and apoptosis and biomarkers of acute kidney injury in...
https://doi.org/10.1080/01480545.2020.1722156
Drug and Chemical Toxicology; Dallak M, Dawood AF et. al.

Feb 2nd, 2020 - Acute renal failure induced by a toxic dose of acetaminophen (also known as paracetamol, or APAP) is common in both humans and experimental animal models. Glomerular ultrastructural alterations induced by APAP overdose associated with the suppress...

Acetaminophen Toxicity
https://emedicine.medscape.com/article/820200-overview

Jan 16th, 2020 - Practice Essentials Acetaminophen is one of the most commonly used oral analgesics and antipyretics. [1] It has an excellent safety profile when administered in proper therapeutic doses, but hepatotoxicity can occur after overdose or when misused ...

Acetaminophen Toxicity 
https://emedicine.medscape.com/article/820200-print

Jan 16th, 2020 - Practice Essentials Acetaminophen is one of the most commonly used oral analgesics and antipyretics.[1] It has an excellent safety profile when administered in proper therapeutic doses, but hepatotoxicity can occur after overdose or when misused i...

Acetaminophen Toxicity Treatment & Management
https://emedicine.medscape.com/article/820200-treatment

Jan 16th, 2020 - Approach Considerations In addition to antidote therapy, supportive care is essential in acetaminophen toxicity. Immediate assessment of the patient's airway, breathing, and hemodynamic status (ie, ABCs) is critical, while considering and initiati...

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Guidelines  2 results

Acetaminophen Toxicity - StatPearls
https://www.ncbi.nlm.nih.gov/books/NBK441917/

Nov 13th, 2018 - Acetaminophen (N-acetyl-para-aminophenol, paracetamol, APAP) toxicity is common primarily because the medication is so readily available and there is a perception that it is very safe. More than 60 million Americans consume acetaminophen on a week...

FAQs on Acetaminophen Use During Pregnancy
www.teratology.org/pdf/Acetaminophen FAQ March 2014.pdf
Teratology Society

Feb 28th, 2014 - A recent article in JAMA (Journal of the American Medical Association) ? Pediatrics reported an increased risk of attention deficit hyperactive disorder (ADHD) and related behavioral problems in children whose mothers took acetaminophen during pre.

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Drugs  1 results see all →

Clinicaltrials.gov  227 results

Cell-permeable succinate prodrugs rescue mitochondrial respiration in cellular models o...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135280
PloS One; Piel S, Chamkha I et. al.

Apr 6th, 2020 - Acetaminophen is one of the most common over-the-counter pain medications used worldwide and is considered safe at therapeutic dose. However, intentional and unintentional overdose accounts for up to 70% of acute liver failure cases in the western...

Suppression of glomerular damage and apoptosis and biomarkers of acute kidney injury in...
https://doi.org/10.1080/01480545.2020.1722156
Drug and Chemical Toxicology; Dallak M, Dawood AF et. al.

Feb 2nd, 2020 - Acute renal failure induced by a toxic dose of acetaminophen (also known as paracetamol, or APAP) is common in both humans and experimental animal models. Glomerular ultrastructural alterations induced by APAP overdose associated with the suppress...

Acetaminophen Toxicity
https://emedicine.medscape.com/article/820200-overview

Jan 16th, 2020 - Practice Essentials Acetaminophen is one of the most commonly used oral analgesics and antipyretics. [1] It has an excellent safety profile when administered in proper therapeutic doses, but hepatotoxicity can occur after overdose or when misused ...

Acetaminophen Toxicity 
https://emedicine.medscape.com/article/820200-print

Jan 16th, 2020 - Practice Essentials Acetaminophen is one of the most commonly used oral analgesics and antipyretics.[1] It has an excellent safety profile when administered in proper therapeutic doses, but hepatotoxicity can occur after overdose or when misused i...

Acetaminophen Toxicity Treatment & Management
https://emedicine.medscape.com/article/820200-treatment

Jan 16th, 2020 - Approach Considerations In addition to antidote therapy, supportive care is essential in acetaminophen toxicity. Immediate assessment of the patient's airway, breathing, and hemodynamic status (ie, ABCs) is critical, while considering and initiati...

see more →

News  31 results

Acetaminophen Toxicity - StatPearls
https://www.ncbi.nlm.nih.gov/books/NBK441917/

Nov 13th, 2018 - Acetaminophen (N-acetyl-para-aminophenol, paracetamol, APAP) toxicity is common primarily because the medication is so readily available and there is a perception that it is very safe. More than 60 million Americans consume acetaminophen on a week...

Acute liver failure in the ED
https://www.mdedge.com/internalmedicine/article/143261/liver-disease/acute-liver-failure-ed
Jennie Smith

Jul 25th, 2017 - Acute liver failure (ALF), is a life-threatening deterioration of liver function in people without preexisting cirrhosis. It can be caused by acetaminophen toxicity, pregnancy, ischemia, hepatitis A infection, and Wilson disease, among other thing.

VIDEO: Point-of-care assay caught acetaminophen toxicity
https://www.mdedge.com/internalmedicine/article/132476/hepatology/video-point-care-assay-caught-acetaminophen-toxicity
Amy Karon

Mar 1st, 2017 - A rapid point-of-care assay for acetaminophen-related liver toxicity had a sensitivity of 100% and a specificity of 86%, compared with etiologic diagnosis, based on the results of a multicenter study published in the April issue of Clinical Gastro.

Acetaminophen Liver Failure Least Likely to Get Transplant
https://www.mdedge.com/internalmedicine/article/56694/gastroenterology/acetaminophen-liver-failure-least-likely-get
Jeff Evans

Nov 12th, 2012 - BOSTON – Acetaminophen toxicity is the most frequent cause of acute liver failure in the United States and its usually milder presentation, along with comorbid psychosocial issues, explain why fewer patients with the etiology undergo liver transpl.

Adolescents, Young Adults Lack Knowledge of Acetaminophen's Toxicity
https://www.medscape.com/viewarticle/721420

May 6th, 2010 - May 7, 2010 (Vancouver, British Columbia) — A study of more than 250 teenagers and young adults by researchers at the University of Rochester, in New York, has found that more than 60% do not know what acetaminophen is, even though a third are use...

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