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About 85 results

ALLMedicine™ Cocaine Toxicity Center

Research & Reviews  32 results

Reengineering of Albumin-Fused Cocaine Hydrolase CocH1 (TV-1380) to Prolong Its Biologi...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7734447
The AAPS Journal; Cai Y, Zhou S et. al.

Nov 23rd, 2019 - Therapeutic treatment of cocaine toxicity or addiction is a grand medical challenge. As a promising therapeutic strategy for treatment of cocaine toxicity and addiction to develop a highly efficient cocaine hydrolase (CocH) capable of accelerating...

In vivo characterization of toxicity of norcocaethylene and norcocaine identified as th...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7737241
Drug and Alcohol Dependence; Zheng X, Shang L et. al.

Sep 10th, 2019 - Majority of cocaine users also consume alcohol, and concurrent use of cocaine and alcohol produces cocaethylene, norcocaine, norcocaethylene, and other non-toxic metabolites. It is essential to know their relative toxicity for development of a tru...

Delirium Tremens (DTs) Differential Diagnoses
https://emedicine.medscape.com/article/166032-differential

Jun 14th, 2019 - Diagnostic Considerations The signs of alcohol withdrawal in critically ill patients, especially if accompanied by delirium, may mimic those of other serious disorders. These disorders may need to be excluded before a firm diagnosis of alcohol wit...

Preventative effects of aripiprazole and quetiapine on seizure and lethality in a mice ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726820
The Journal of International Medical Research; Yilmaz A, Erdur B et. al.

Jun 13th, 2019 - Preventative effects of aripiprazole and quetiapine on seizure and lethality in a mice cocaine toxicity model: an experimental study.|2019|Yilmaz A,Erdur B,Ozen M,Sabirli R,Turkcuer I,|toxicity,pharmacology,pharmacology,toxicity,etiology,mortality...

Authors' reply to comment on "Epidemiology, clinical features and management of patient...
https://doi.org/10.1080/15563650.2019.1613549
Clinical Toxicology (Philadelphia, Pa.); Miró Ò, Dargan PI et. al.

May 17th, 2019 - Authors' reply to comment on "Epidemiology, clinical features and management of patients presenting to European emergency departments with acute cocaine toxicity: comparison between powder cocaine and crack cocaine cases".|2019|Miró Ò,Dargan PI,Ga...

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News  2 results

Landmark Resuscitation Study: The FOAMed Report
https://www.medpagetoday.com/emergencymedicine/emergencymedicine/49998

Feb 12th, 2015 - A landmark study is out: PROPPR. It's a randomized trial in JAMA investigating outcomes between 1:1:1 versus 1:1:2 plasma:platelet:pRBC transfusion ratios, and #FOAMed is all atwitter about it. Check out HippoEM's discussion, REBEL EM's (quite lit...

Guidance Offered on Cocaine-Related Chest Pain
https://www.mdedge.com/cardiology/article/41562/acute-coronary-syndromes/guidance-offered-cocaine-related-chest-pain
Mary Ann Moon

Patients who present with cocaine-associated chest pain or myocardial infarction should be treated similarly to patients with traditional acute coronary syndromes, with some exceptions, according to Dr. Jim McCord and his associates on the America.

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