×
About 3,909 results

ALLMedicine™ Opioid Abuse Center

Research & Reviews  1,485 results

Opioid prescribing and health outcomes in opioid-naive patients: Analysis of a statewid...
https://doi.org/10.1016/j.japh.2021.04.020
Journal of the American Pharmacists Association : JAPhA; Udayachalerm S, Bair MJ et. al.

May 28th, 2021 - Widespread use of prescription opioids is associated with adverse outcomes. To identify factors associated with adverse health outcomes and health care use using a statewide health information exchange. This is a retrospective cohort study using t...

Can FDA-Approved Immunomodulatory Drugs be Repurposed/Repositioned to Alleviate Chronic...
https://doi.org/10.1007/s11481-021-10000-z 10.1124/jpet.106.103192 10.1016/j.imlet.2007.07.009 10.1073/pnas.94.20.10821 10.1016/S0165-5728(98)00166-0 10.1016/j.pain.2005.04.013 10.1186/s12974-016-0625-4 10.1096/fj.02-1169fje 10.1097/BOR.0000000000000370 10.1016/j.immuni.2013.10.016 10.1016/j.chom.2016.05.010 10.1097/00001756-200111160-00020 10.1186/s12974-016-0591-x 10.1016/j.neulet.2013.08.026 10.1126/science.1067859 10.1038/nn.3155 10.2147/DDDT.S253232 10.36076/ppj.2008/11/S105 10.1038/emboj.2011.89 10.1164/ajrccm/143.3_Pt_2.S55 10.1523/JNEUROSCI.3795-08.2008 10.1007/s00415-008-1005-5 10.1016/j.pain.2011.11.013 10.1002/jnr.23768 10.1001/jama.2018.18472 10.1093/neuonc/nov245 10.1002/eji.200737485 10.1038/s41467-019-11139-3 10.1371/journal.pone.0084718 10.1016/j.cellsig.2009.04.003 10.1016/j.bbrc.2012.07.074 10.1111/pme.12915 10.1038/nn.3144 10.1038/nrdp.2017.2 10.1016/S0022-510X(01)00684-0 10.1002/art.39031 10.1016/S0304-3940(00)01289-1 10.1053/j.gastro.2015.01.042 10.1001/jama.2016.1464 10.1111/j.1365-2222.1994.tb00964.x 10.1186/s13287-018-0896-z 10.1016/S1474-4422(14)70251-0 10.1073/pnas.1902091116 10.1007/DCR.0b013e3181973487 10.1016/0165-0173(94)00015-H 10.1016/j.clinthera.2016.03.008 10.1038/nm.2235 10.3389/fimmu.2019.03061 10.1016/j.neuron.2019.01.012 10.1002/j.1552-4604.1981.tb01755.x 10.1038/nn.4189 10.1111/irv.12334 10.1038/nrm2249 10.1097/j.pain.0000000000001623 10.1016/j.neubiorev.2017.05.001 10.1213/ANE.0000000000005302 10.1084/jem.183.6.2627 10.1016/0002-9343(83)90477-1 10.3389/fncel.2019.00525 10.1016/0091-6749(90)90067-E 10.1016/S0014-4886(03)00307-8 10.1038/nrn.2018.2 10.1016/j.phrs.2018.10.027 10.1080/15563650.2018.1484128 10.1007/s00210-017-1426-8 10.1038/nrd4334 10.1016/j.tins.2011.08.005 10.1038/35093019 10.1002/ajh.20708 10.1038/s41375-020-0956-0 10.1016/S0169-328X(98)00346-5 10.1523/JNEUROSCI.3338-07.2008 10.2147/JPR.S128520 10.1016/j.tins.2017.11.006 10.1097/j.pain.0000000000001042 10.1210/en.2011-2120 10.1038/nm.3432 10.1523/JNEUROSCI.3708-15.2016 10.1016/S1734-1140(10)70343-1 10.1007/s40265-019-01210-0 10.1007/s00415-018-8748-4 10.1016/S0091-6749(98)70376-8 10.1097/j.pain.0000000000001921 10.1007/978-3-319-49795-2_6 10.1038/s41386-018-0154-1 10.3389/fnmol.2019.00216 10.1016/j.bbi.2006.10.012 10.1016/j.jneuroim.2011.01.005 10.1016/j.bbi.2011.09.016 10.1097/ALN.0000000000003077 10.1177/0271678X16666551 10.1136/ard.2009.123463 10.1093/brain/awq386 10.1016/j.nurt.2010.07.002 10.1186/s12974-016-0565-z 10.1111/j.1471-4159.2005.03050.x 10.1016/0006-8993(93)91446-Y 10.1016/j.pain.2013.03.028 10.1098/rstb.1996.0039 10.1186/1744-8069-7-70 10.1016/j.jaci.2006.03.031 10.1017/S1740925X07000488 10.1016/j.immuni.2011.12.012 10.1016/j.neuroscience.2004.08.035 10.1038/s41583-020-0310-6 10.1016/j.autrev.2018.07.001 10.1146/annurev.immunol.19.1.683 10.1523/JNEUROSCI.1786-18.2019 10.1136/gutjnl-2013-305947 10.1038/nature01320 10.1016/j.cell.2017.08.006 10.1111/j.1365-2222.1992.tb03102.x 10.1371/journal.pone.0153375 10.1172/JCI71389 10.1016/j.ejphar.2011.10.001 10.1007/s00520-017-3760-2 10.1016/j.ymthe.2018.04.022 10.1186/s13075-017-1305-1 10.1038/ncomms12029 10.1111/bph.12645 10.1002/art.1780400305 10.1016/j.it.2016.10.001 10.1001/archneurol.2010.191 10.1124/jpet.103.052407 10.1016/S0140-6736(13)62337-5 10.1016/j.neuroscience.2014.05.051 10.1097/j.pain.0000000000001420 10.1016/j.ijdevneu.2019.01.007 10.1097/j.pain.0000000000001383 10.1523/JNEUROSCI.2785-18.2018 10.1586/14737175.7.11.1613 10.1111/nyas.12417 10.1634/stemcells.2007-0554 10.1021/acs.bioconjchem.7b00569 10.1523/JNEUROSCI.3542-17.2018 10.1073/pnas.1721815115 10.1213/ANE.0000000000003857 10.1016/S0304-3940(99)00701-6 10.1038/s41467-017-01841-5 10.1056/NEJMra033121 10.1016/j.tips.2015.11.006 10.1097/j.pain.0000000000000369 10.1097/00019052-200310000-00009 10.1038/nn.4053 10.1001/archinte.163.3.265 10.1038/nature04671 10.1016/j.molimm.2016.08.006 10.1038/s41598-019-52234-1 10.1016/S0140-6736(19)30764-0 10.1016/j.mcn.2016.01.006 10.1097/j.pain.0000000000000228 10.1038/nature01786 10.1212/01.wnl.0000265062.92340.a5 10.1371/journal.pone.0028205 10.1002/art.22026 10.1097/ALN.0000000000000508 10.1038/nm.3852 10.1182/blood-2013-04-498105 10.3389/fphar.2019.00607 10.3389/fphar.2017.00758 10.1016/j.neuron.2012.02.008 10.1016/j.semcdb.2017.02.002 10.1016/j.bbi.2020.08.005 10.1152/physrev.00011.2002 10.1016/0006-8993(94)91566-0 10.1073/pnas.0507321103 10.1016/j.pain.2010.06.015 10.1212/WNL.45.6_Suppl_6.S6 10.1016/j.neuron.2007.07.016 10.1002/jnr.10709 10.3344/kjp.2020.33.1.23 10.1073/pnas.96.23.13496 10.1007/s12031-019-01352-6 10.1186/s12990-015-0002-9 10.1038/s41467-019-13839-2 10.1111/cns.12305 10.1016/j.jpain.2016.02.011
Journal of Neuroimmune Pharmacology : the Official Journa... Inyang KE, Folger JK et. al.

May 27th, 2021 - Pain is among the most widespread chronic health condition confronting society today and our inability to manage chronic pain contributes to the opioid abuse epidemic in America. The immune system is known to contribute to acute and chronic pain, ...

How Do Clinicians of Different Specialties Perceive and Use Opioid Risk Mitigation Stra...
https://doi.org/10.1080/10826084.2021.1926514
Substance Use & misUse; Keller MS, Jusufagic A et. al.

May 24th, 2021 - In response to the opioid crisis, states and health systems are encouraging clinicians to use risk mitigation strategies aimed at assessing a patient's risk for opioid misuse or abuse: opioid agreements, prescription drug monitoring programs (PDMP...

Effects of maternal consumption of morphine on rat skeletal system development.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120720
BMC Musculoskeletal Disorders; Saeidinezhad M, Razban V et. al.

May 14th, 2021 - Opioid abuse is among the most ubiquitous issues world-wide, and when it happens in mothers, it puts them at risk of diseases that can be transferred to the next generation. Previous studies have indicated that morphine addiction during pregnancy ...

Paradoxical changes in brain reward status during oxycodone self-administration in a no...
https://doi.org/10.1111/bph.15520
British Journal of Pharmacology; Nguyen JD, Grant Y et. al.

May 5th, 2021 - The extra medical use of, and addiction to, prescription opioid analgesics is a growing health problem. To characterize how prescription opioid abuse develops, this study investigated the affective consequences of escalating prescription opioid us...

see more →

Guidelines  83 results

Opioid Medications | FDA
https://www.fda.gov/drugs/information-drug-class/opioid-medications

Jun 30th, 2019 - FDA takes actions to combat prescription opioid abuse. Prescription opioids are powerful pain-reducing medications that include prescription oxycodone, hydrocodone and morphine. These medications can help manage pain when prescribed for the right ...

A Transitioning Epidemic: How The Opioid Crisis Is Driving The Rise In Hepatitis C
https://www.healthaffairs.org/doi/abs/10.1377/hlthaff.2018.05232?journalCode=hlthaff
Powell,D.,et al

Feb 3rd, 2019 - The hepatitis C virus is responsible for more deaths in the United States than any other infectious disease, and hepatitis C infections have been rising at an alarming rate since 2010. We evaluated the role of the opioid epidemic and, in particula...

Effective management of opioid withdrawal symptoms: A gateway to opioid dependence treatment
https://onlinelibrary.wiley.com/doi/full/10.1111/ajad.12862
Kosten,T.,et al

Jan 30th, 2019 - The opioid crisis has taken an immense toll in the United States. On average, five lives are lost to an opioid overdose every hour of the day; estimated costs associated with opioid misuse exceed $500 billion annually. Illicit opioid discontinuati...

National Trends in Hospitalizations for Stroke Associated With Infective Endocarditis and Opioid Use Between 1993 and 2015
https://www.ahajournals.org/doi/pdf/10.1161/STROKEAHA.118.024436
Omran,S.,et al

Jan 29th, 2019 - There has been a recent sharp rise in opioid-related deaths in the United States. Intravenous opioid use can lead to infective endocarditis (IE) which can result in stroke. There are scant data on recent trends in this neurological complication of...

Challenges with Implementing the Centers for Disease Control and Prevention Opioid Guideline: A Consensus Panel Report
https://academic.oup.com/painmedicine/advance-article-abstract/doi/10.1093/pm/pny307/5301726?redirectedFrom=fulltext
Kroenke,K.,et al

Jan 24th, 2019 - A national crisis of opioid-related morbidity, mortality, and misuse has led to initiatives to address the appropriate role of opioids to treat pain. Deployment of a guideline from the Centers for Disease Control and Prevention to reduce the risks...

see more →

Drugs  7 results see all →

Clinicaltrials.gov  1,891 results

Opioid prescribing and health outcomes in opioid-naive patients: Analysis of a statewid...
https://doi.org/10.1016/j.japh.2021.04.020
Journal of the American Pharmacists Association : JAPhA; Udayachalerm S, Bair MJ et. al.

May 28th, 2021 - Widespread use of prescription opioids is associated with adverse outcomes. To identify factors associated with adverse health outcomes and health care use using a statewide health information exchange. This is a retrospective cohort study using t...

Can FDA-Approved Immunomodulatory Drugs be Repurposed/Repositioned to Alleviate Chronic...
https://doi.org/10.1007/s11481-021-10000-z 10.1124/jpet.106.103192 10.1016/j.imlet.2007.07.009 10.1073/pnas.94.20.10821 10.1016/S0165-5728(98)00166-0 10.1016/j.pain.2005.04.013 10.1186/s12974-016-0625-4 10.1096/fj.02-1169fje 10.1097/BOR.0000000000000370 10.1016/j.immuni.2013.10.016 10.1016/j.chom.2016.05.010 10.1097/00001756-200111160-00020 10.1186/s12974-016-0591-x 10.1016/j.neulet.2013.08.026 10.1126/science.1067859 10.1038/nn.3155 10.2147/DDDT.S253232 10.36076/ppj.2008/11/S105 10.1038/emboj.2011.89 10.1164/ajrccm/143.3_Pt_2.S55 10.1523/JNEUROSCI.3795-08.2008 10.1007/s00415-008-1005-5 10.1016/j.pain.2011.11.013 10.1002/jnr.23768 10.1001/jama.2018.18472 10.1093/neuonc/nov245 10.1002/eji.200737485 10.1038/s41467-019-11139-3 10.1371/journal.pone.0084718 10.1016/j.cellsig.2009.04.003 10.1016/j.bbrc.2012.07.074 10.1111/pme.12915 10.1038/nn.3144 10.1038/nrdp.2017.2 10.1016/S0022-510X(01)00684-0 10.1002/art.39031 10.1016/S0304-3940(00)01289-1 10.1053/j.gastro.2015.01.042 10.1001/jama.2016.1464 10.1111/j.1365-2222.1994.tb00964.x 10.1186/s13287-018-0896-z 10.1016/S1474-4422(14)70251-0 10.1073/pnas.1902091116 10.1007/DCR.0b013e3181973487 10.1016/0165-0173(94)00015-H 10.1016/j.clinthera.2016.03.008 10.1038/nm.2235 10.3389/fimmu.2019.03061 10.1016/j.neuron.2019.01.012 10.1002/j.1552-4604.1981.tb01755.x 10.1038/nn.4189 10.1111/irv.12334 10.1038/nrm2249 10.1097/j.pain.0000000000001623 10.1016/j.neubiorev.2017.05.001 10.1213/ANE.0000000000005302 10.1084/jem.183.6.2627 10.1016/0002-9343(83)90477-1 10.3389/fncel.2019.00525 10.1016/0091-6749(90)90067-E 10.1016/S0014-4886(03)00307-8 10.1038/nrn.2018.2 10.1016/j.phrs.2018.10.027 10.1080/15563650.2018.1484128 10.1007/s00210-017-1426-8 10.1038/nrd4334 10.1016/j.tins.2011.08.005 10.1038/35093019 10.1002/ajh.20708 10.1038/s41375-020-0956-0 10.1016/S0169-328X(98)00346-5 10.1523/JNEUROSCI.3338-07.2008 10.2147/JPR.S128520 10.1016/j.tins.2017.11.006 10.1097/j.pain.0000000000001042 10.1210/en.2011-2120 10.1038/nm.3432 10.1523/JNEUROSCI.3708-15.2016 10.1016/S1734-1140(10)70343-1 10.1007/s40265-019-01210-0 10.1007/s00415-018-8748-4 10.1016/S0091-6749(98)70376-8 10.1097/j.pain.0000000000001921 10.1007/978-3-319-49795-2_6 10.1038/s41386-018-0154-1 10.3389/fnmol.2019.00216 10.1016/j.bbi.2006.10.012 10.1016/j.jneuroim.2011.01.005 10.1016/j.bbi.2011.09.016 10.1097/ALN.0000000000003077 10.1177/0271678X16666551 10.1136/ard.2009.123463 10.1093/brain/awq386 10.1016/j.nurt.2010.07.002 10.1186/s12974-016-0565-z 10.1111/j.1471-4159.2005.03050.x 10.1016/0006-8993(93)91446-Y 10.1016/j.pain.2013.03.028 10.1098/rstb.1996.0039 10.1186/1744-8069-7-70 10.1016/j.jaci.2006.03.031 10.1017/S1740925X07000488 10.1016/j.immuni.2011.12.012 10.1016/j.neuroscience.2004.08.035 10.1038/s41583-020-0310-6 10.1016/j.autrev.2018.07.001 10.1146/annurev.immunol.19.1.683 10.1523/JNEUROSCI.1786-18.2019 10.1136/gutjnl-2013-305947 10.1038/nature01320 10.1016/j.cell.2017.08.006 10.1111/j.1365-2222.1992.tb03102.x 10.1371/journal.pone.0153375 10.1172/JCI71389 10.1016/j.ejphar.2011.10.001 10.1007/s00520-017-3760-2 10.1016/j.ymthe.2018.04.022 10.1186/s13075-017-1305-1 10.1038/ncomms12029 10.1111/bph.12645 10.1002/art.1780400305 10.1016/j.it.2016.10.001 10.1001/archneurol.2010.191 10.1124/jpet.103.052407 10.1016/S0140-6736(13)62337-5 10.1016/j.neuroscience.2014.05.051 10.1097/j.pain.0000000000001420 10.1016/j.ijdevneu.2019.01.007 10.1097/j.pain.0000000000001383 10.1523/JNEUROSCI.2785-18.2018 10.1586/14737175.7.11.1613 10.1111/nyas.12417 10.1634/stemcells.2007-0554 10.1021/acs.bioconjchem.7b00569 10.1523/JNEUROSCI.3542-17.2018 10.1073/pnas.1721815115 10.1213/ANE.0000000000003857 10.1016/S0304-3940(99)00701-6 10.1038/s41467-017-01841-5 10.1056/NEJMra033121 10.1016/j.tips.2015.11.006 10.1097/j.pain.0000000000000369 10.1097/00019052-200310000-00009 10.1038/nn.4053 10.1001/archinte.163.3.265 10.1038/nature04671 10.1016/j.molimm.2016.08.006 10.1038/s41598-019-52234-1 10.1016/S0140-6736(19)30764-0 10.1016/j.mcn.2016.01.006 10.1097/j.pain.0000000000000228 10.1038/nature01786 10.1212/01.wnl.0000265062.92340.a5 10.1371/journal.pone.0028205 10.1002/art.22026 10.1097/ALN.0000000000000508 10.1038/nm.3852 10.1182/blood-2013-04-498105 10.3389/fphar.2019.00607 10.3389/fphar.2017.00758 10.1016/j.neuron.2012.02.008 10.1016/j.semcdb.2017.02.002 10.1016/j.bbi.2020.08.005 10.1152/physrev.00011.2002 10.1016/0006-8993(94)91566-0 10.1073/pnas.0507321103 10.1016/j.pain.2010.06.015 10.1212/WNL.45.6_Suppl_6.S6 10.1016/j.neuron.2007.07.016 10.1002/jnr.10709 10.3344/kjp.2020.33.1.23 10.1073/pnas.96.23.13496 10.1007/s12031-019-01352-6 10.1186/s12990-015-0002-9 10.1038/s41467-019-13839-2 10.1111/cns.12305 10.1016/j.jpain.2016.02.011
Journal of Neuroimmune Pharmacology : the Official Journa... Inyang KE, Folger JK et. al.

May 27th, 2021 - Pain is among the most widespread chronic health condition confronting society today and our inability to manage chronic pain contributes to the opioid abuse epidemic in America. The immune system is known to contribute to acute and chronic pain, ...

How Do Clinicians of Different Specialties Perceive and Use Opioid Risk Mitigation Stra...
https://doi.org/10.1080/10826084.2021.1926514
Substance Use & misUse; Keller MS, Jusufagic A et. al.

May 24th, 2021 - In response to the opioid crisis, states and health systems are encouraging clinicians to use risk mitigation strategies aimed at assessing a patient's risk for opioid misuse or abuse: opioid agreements, prescription drug monitoring programs (PDMP...

Effects of maternal consumption of morphine on rat skeletal system development.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120720
BMC Musculoskeletal Disorders; Saeidinezhad M, Razban V et. al.

May 14th, 2021 - Opioid abuse is among the most ubiquitous issues world-wide, and when it happens in mothers, it puts them at risk of diseases that can be transferred to the next generation. Previous studies have indicated that morphine addiction during pregnancy ...

Paradoxical changes in brain reward status during oxycodone self-administration in a no...
https://doi.org/10.1111/bph.15520
British Journal of Pharmacology; Nguyen JD, Grant Y et. al.

May 5th, 2021 - The extra medical use of, and addiction to, prescription opioid analgesics is a growing health problem. To characterize how prescription opioid abuse develops, this study investigated the affective consequences of escalating prescription opioid us...

see more →

News  441 results

Opioid Prescribing for High-Risk Patients Continues to Rise
https://www.medscape.com/viewarticle/942287

Dec 8th, 2020 - Since the publication of the Centers for Disease Control and Prevention's (CDC's) opioid guideline in March 2016, there has been a substantial drop in the prescription rate for these medications ― except for patients at highest risk for opioid abu...

NSAID Allergy Ups Risk for Opioid Abuse in Osteoarthritis
https://www.medscape.com/viewarticle/941443

Nov 22nd, 2020 - Patients with osteoarthritis and an allergy to nonsteroidal anti-inflammatory drugs (NSAIDs) are more likely to become addicted to opioids than nonallergic patients, according to a 5-year retrospective analysis. In fact, the risk of developing an ...

Dangers of a Medical Board Investigation: How to Protect Yourself
https://www.medscape.com/viewarticle/940672

Nov 9th, 2020 - Cynthia H. Moran, MD, has a medical degree, a passion for treating the elderly, and a desire to work. What she doesn't have is a job or hopes of getting one anytime soon. The Houston physician has never been charged with a crime, but she did run a...

US Prescription Opioid Abuse Was Declining Before Pandemic
https://www.staging.medscape.com/viewarticle/939056

Oct 13th, 2020 - NEW YORK (Reuters Health) - Prescription opioid abuse in the United States declined dramatically from 2009 to 2018, raw data indicate. Weighted data also showed a statistically significant decline, although less dramatic, according to findings pre...

US Prescription Opioid Abuse Was Declining Before Pandemic
https://www.medscape.com/viewarticle/939056

Oct 13th, 2020 - NEW YORK (Reuters Health) - Prescription opioid abuse in the United States declined dramatically from 2009 to 2018, raw data indicate. Weighted data also showed a statistically significant decline, although less dramatic, according to findings pre...

see more →

Patient Education  2 results see all →