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About 248 results

ALLMedicine™ Opioid Toxicity Center

Research & Reviews  113 results

Fentanyl contaminated "M30" pill overdoses in pediatric patients.
https://doi.org/10.1016/j.ajem.2021.05.035
The American Journal of Emergency Medicine; Joynt PY, Wang GS

May 25th, 2021 - Fentanyl is a high potency opioid that has become an increasingly large proportion of the illicit drug supply. Fentanyl overdoses and deaths, including in pediatric patients, has concomitantly increased. To describe two cases of pediatric fentanyl...

Cardiovascular Complications of Opioid Use: JACC State-of-the-Art Review.
https://doi.org/10.1016/j.jacc.2020.11.002
Journal of the American College of Cardiology; Krantz MJ, Palmer RB et. al.

Jan 15th, 2021 - Opioids are the most potent of all analgesics. Although traditionally used solely for acute self-limited conditions and palliation of severe cancer-associated pain, a movement to promote subjective pain (scale, 0 to 10) to the status of a "fifth v...

Fentanyl-contaminated cocaine outbreak with laboratory confirmation in New York City in...
https://doi.org/10.1016/j.ajem.2020.12.002
The American Journal of Emergency Medicine; DiSalvo P, Cooper G et. al.

Dec 28th, 2020 - Illicitly manufactured fentanyl and fentanyl analogues (IMFs) are being increasingly suspected in overdose deaths. However, few prior outbreaks have been reported thus far of patients with laboratory-confirmed IMF toxicity after reporting intent t...

A study of the effectiveness of naltrexone in preventing recurrence of methadone poison...
https://doi.org/10.1016/j.drugalcdep.2020.108425
Drug and Alcohol Dependence; Gholami N, Farnaghi F et. al.

Dec 8th, 2020 - The prevalence of poisoning from methadone and prescription opioids is increasing in pediatric populations. Naloxone is the main antidote for treatment. Long-acting opioid toxicity may need close observation in the intensive care unit (ICU). In ou...

Countermeasures for Preventing and Treating Opioid Overdose.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193687
Clinical Pharmacology and Therapeutics; France CP, Ahern GP et. al.

Oct 28th, 2020 - The only medication available currently to prevent and treat opioid overdose (naloxone) was approved by the US Food and Drug Administration (FDA) nearly 50 years ago. Because of its pharmacokinetic and pharmacodynamic properties, naloxone has limi...

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Guidelines  4 results

Fentanyl and Other Synthetic Opioids Drug Overdose Deaths
https://www.drugabuse.gov/related-topics/trends-statistics/infographics/fentanyl-other-synthetic-opioids-drug-overdose-deaths

Apr 30th, 2018 - In 2016, synthetic opioids (primarily illegal fentanyl) passed prescription opioids as the most common drugs involved in overdose deaths in the United States.

ACMT and AACT position statement: preventing occupational fentanyl and fentanyl analog expos...
http://www.tandfonline.com/doi/full/10.1080/15563650.2017.1373782
Michael J. Moss

Aug 23rd, 2017 - Fentanyl and its analogs are potent opioid receptor agonists, but the risk of clinically significant exposure to emergency responders is extremely low. To date, we have not seen reports of emergency responders developing signs or symptoms consiste.

The general surgeon’s role in enhancing patient education about prescription opioids: ACS Gu...
http://bulletin.facs.org/2017/08/the-general-surgeons-role-in-enhancing-patient-education-about-prescription-opioids/#.WmZS6ainG1s
MADELINE TORRES

Aug 1st, 2017 - Understanding the patient population within the surgeon’s geographic practice area is important to determine which patients may potentially seek increased opioid prescriptions versus those who choose not to use narcotic pain management due to soci.

Use of Naloxone for the Prevention of Opioid Overdose Deaths: ASAM Guideline
https://asam.org/advocacy/find-a-policy-statement/view-policy-statement/public-policy-statements/2014/08/28/use-of-naloxone-for-the-prevention-of-drug-overdose-deaths
American Society of Addiction Medicine

Oct 7th, 2016 - Naloxone is a mu-opioid antagonist with well-established safety and efficacy that can reverse opioid overdose and prevent fatalities. Naloxone treatment of opioid overdose has been in use in hospital settings for decades.

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Drugs  1 results see all →

Clinicaltrials.gov  125 results

Fentanyl contaminated "M30" pill overdoses in pediatric patients.
https://doi.org/10.1016/j.ajem.2021.05.035
The American Journal of Emergency Medicine; Joynt PY, Wang GS

May 25th, 2021 - Fentanyl is a high potency opioid that has become an increasingly large proportion of the illicit drug supply. Fentanyl overdoses and deaths, including in pediatric patients, has concomitantly increased. To describe two cases of pediatric fentanyl...

Cardiovascular Complications of Opioid Use: JACC State-of-the-Art Review.
https://doi.org/10.1016/j.jacc.2020.11.002
Journal of the American College of Cardiology; Krantz MJ, Palmer RB et. al.

Jan 15th, 2021 - Opioids are the most potent of all analgesics. Although traditionally used solely for acute self-limited conditions and palliation of severe cancer-associated pain, a movement to promote subjective pain (scale, 0 to 10) to the status of a "fifth v...

Fentanyl-contaminated cocaine outbreak with laboratory confirmation in New York City in...
https://doi.org/10.1016/j.ajem.2020.12.002
The American Journal of Emergency Medicine; DiSalvo P, Cooper G et. al.

Dec 28th, 2020 - Illicitly manufactured fentanyl and fentanyl analogues (IMFs) are being increasingly suspected in overdose deaths. However, few prior outbreaks have been reported thus far of patients with laboratory-confirmed IMF toxicity after reporting intent t...

A study of the effectiveness of naltrexone in preventing recurrence of methadone poison...
https://doi.org/10.1016/j.drugalcdep.2020.108425
Drug and Alcohol Dependence; Gholami N, Farnaghi F et. al.

Dec 8th, 2020 - The prevalence of poisoning from methadone and prescription opioids is increasing in pediatric populations. Naloxone is the main antidote for treatment. Long-acting opioid toxicity may need close observation in the intensive care unit (ICU). In ou...

Countermeasures for Preventing and Treating Opioid Overdose.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193687
Clinical Pharmacology and Therapeutics; France CP, Ahern GP et. al.

Oct 28th, 2020 - The only medication available currently to prevent and treat opioid overdose (naloxone) was approved by the US Food and Drug Administration (FDA) nearly 50 years ago. Because of its pharmacokinetic and pharmacodynamic properties, naloxone has limi...

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News  5 results

Assessing adverse events tied to outpatient opioid use in children
https://www.mdedge.com/neurology/article/170349/pain/assessing-adverse-events-tied-outpatient-opioid-use-children
Heidi Splete

Jul 16th, 2018 - Nearly three-quarters of opioid-related adverse events seen in children were related to therapeutic opioid use, based on data from more than a million prescriptions. BackyardProduction/Thinkstock Prescription of opioids to children for outpatient.

Fentanyl and Other Synthetic Opioids Drug Overdose Deaths
https://www.drugabuse.gov/related-topics/trends-statistics/infographics/fentanyl-other-synthetic-opioids-drug-overdose-deaths

Apr 30th, 2018 - In 2016, synthetic opioids (primarily illegal fentanyl) passed prescription opioids as the most common drugs involved in overdose deaths in the United States.

Reports of Incidental Fentanyl Exposure Exaggerate Danger (STAT)
https://www.medpagetoday.com/emergencymedicine/emergencymedicine/67203

Aug 10th, 2017 - Media reports linking brief, incidental fentanyl exposure to opioid toxicity may exaggerate the dangers to first responders and others, according to STAT News. Although the synthetic opioid is 50 to 100 times more potent than morphine, experts tol...

Case Studies in Toxicology: Double Take—Is Re-exposure Necessary to Explain Delayed Recurrent Opioid Toxicity?
https://www.mdedge.com/emergencymedicine/article/98183/toxicology/case-studies-toxicology-double-take-re-exposure-necessary/page/0/1

Mar 1st, 2015 - Patients presenting with heroin overdose should be monitored for at least 2 hours after naloxone administration (some suggest 3 hours) to determine whether or not additional dosing will be necessary. After oral opioid exposures, particularly with.

Drugs in Pregnancy and Lactation: Literature and Resource Update
https://www.medscape.com/viewarticle/716435_6

Codeine In 2007, the FDA notified health care providers of the risk to breastfeeding infants from maternal use of acetaminophen with codeine. The advisory came as the result of the death of a healthy newborn the previous year. Further investigatio...

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