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About 148 results

ALLMedicine™ Withdrawal Syndromes Center

Research & Reviews  56 results

Antidepressants produce persistent Gαs associated signaling changes in lipid rafts foll...
https://doi.org/10.1124/molpharm.120.000226
Molecular Pharmacology; Senese NB, Rasenick MM

May 21st, 2021 - Termination of antidepressant therapy often has negative consequences. While symptoms of antidepressant withdrawal are widely recognized, the molecular processes that underlie them are not well characterized. We show that certain aspects of Gαs si...

Similarities in alcohol and opioid withdrawal syndromes suggest common negative reinfor...
https://doi.org/10.1016/j.neubiorev.2021.02.033
Neuroscience and Biobehavioral Reviews; O'Sullivan SJ, Schwaber JS

Mar 2nd, 2021 - Alcohol and opioids are two major contributors to so-called deaths of despair. Though the effects of these substances on mammalian systems are distinct, commonalities in their withdrawal syndromes suggest a shared pathophysiology. For example, bot...

Pharmacological uses of flumazenil in benzodiazepine use disorders: a systematic review...
https://doi.org/10.1177/0269881120981390
Journal of Psychopharmacology (Oxford, England); Gallo AT, Hulse G

Jan 12th, 2021 - The estimated annual prevalence of drug use disorders is as high as 3%, underpinning the need to continually develop more effective treatments. Central nervous system dysregulation, contributing to acute and post-withdrawal syndromes, has traditio...

Continuous Intrathecal Morphine Infusion for Pain Management in a Polytrauma Patient: A...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672713
A&A Practice; Boncyk CS, Brennan KA et. al.

Nov 14th, 2020 - Polytrauma patients are at high risk for neurologic complications as a result of the primary mechanism of their trauma and/or delirium caused by subsequent pain, sedatives and analgesic exposure, sleep disturbances, infections, metabolic derangeme...

Pharmacotherapeutic management of acute alcohol withdrawal syndrome in critically Ill p...
https://doi.org/10.1080/14656566.2020.1746271
Expert Opinion on Pharmacotherapy; Glahn A, Proskynitopoulos PJ et. al.

Apr 14th, 2020 - Alcohol withdrawal syndrome is a common and life-threatening condition in patients suffering from alcohol use disorder. Treatment of this syndrome is challenging, especially in patients that are critically ill, either because of withdrawal symptom...

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Drugs  1 results see all →

Clinicaltrials.gov  1 results

Acute Withdrawal From Smoked Cocaine - 9
https://clinicaltrials.gov/ct2/show/NCT00000292

Jan 12th, 2017 - Although there are clearly identifiable withdrawal syndromes following cessation of a number of abused drugs such as alcohol and heroin, it is unclear whether a withdrawal syndrome follows the cessation of crack cocaine. A laboratory model of with...

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News  1 results

Medtronic Infusion Pump Recalled
https://www.medpagetoday.com/painmanagement/painmanagement/28473

Sep 12th, 2011 - Battery problems with two of Medtronic's SynchroMed II implantable infusion pumps have forced the company to recall them, according to the FDA, although the recall only affects products not yet implanted. The company has determined that the batter...

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