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About 293 results

ALLMedicine™ Acetaminophen Toxicity Center

Research & Reviews  97 results

Severe Anion Gap Metabolic Acidosis Resulting from Combined Chronic Acetaminophen Toxic...
https://doi.org/10.12659/AJCR.934410
The American Journal of Case Reports; Kalinoski T

Jan 18th, 2022 - BACKGROUND Chronic acetaminophen toxicity has been known to cause an anion gap metabolic acidosis (AGMA) due to accumulation of 5-oxoproline metabolites. This diagnosis requires a high index of suspicion when evaluating a patient with AGMA as occa...

A Multi-Center Trial to Study Acute Liver Failure in Adults
https://clinicaltrials.gov/ct2/show/NCT00518440

Dec 27th, 2021 - Although ALF is truly an orphan disease affecting only about 2,000 persons per year, its severity, its frequency among young adults, and its high resource utilization justifies the attention paid to it. In addition, ALF has captured the interest a...

Prognostic factors of acetaminophen exposure in the United States: An analysis of 39,00...
https://doi.org/10.1177/09603271211061503
Human & Experimental Toxicology; Mehrpour O, Saeedi F et. al.

Nov 14th, 2021 - Acetaminophen is a frequently used over-the-counter or prescribed medication in the United States. Exposure to acetaminophen can lead to acute liver cytolysis, acute liver failure, acute kidney injury, encephalopathy, and coagulopathy. This retros...

Acetaminophen Toxicity Medication
http://emedicine.medscape.com/article/820200-medication

Oct 5th, 2021 - Medication Summary Activated charcoal (AC) and N-acetylcysteine (NAC) are used in the treatment of acetaminophen toxicity. Antiemetics are used to relieve nausea and vomiting, which can result from both acetaminophen toxicity and from AC and oral ...

Acetaminophen Toxicity Treatment & Management
http://emedicine.medscape.com/article/820200-treatment

Oct 5th, 2021 - Approach Considerations In addition to antidote therapy, supportive care is essential in acetaminophen toxicity. Immediate assessment of the patient's airway, breathing, and hemodynamic status (ie, ABCs) is critical, while considering and initiati...

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Drugs  1 results see all →

Clinicaltrials.gov  4 results

A Multi-Center Trial to Study Acute Liver Failure in Adults
https://clinicaltrials.gov/ct2/show/NCT00518440

Dec 27th, 2021 - Although ALF is truly an orphan disease affecting only about 2,000 persons per year, its severity, its frequency among young adults, and its high resource utilization justifies the attention paid to it. In addition, ALF has captured the interest a...

The ACTS Trial: N-acetylcysteine (NAC) and Night-splinting as a Non-operative Treatment for Carpal Tunnel Syndrome
https://clinicaltrials.gov/ct2/show/NCT04460521

Aug 9th, 2021 - Introduction: Carpal tunnel syndrome (CTS) is the most prevalent and widely studied peripheral nerve entrapment syndrome, with estimates between 10-20% of the general population having clinical symptoms of CTS at least once in their lifetime. Clas...

Study of N-Acetylcysteine in Acute Liver Failure (ALF)
https://clinicaltrials.gov/ct2/show/NCT00896025

Jun 1st, 2020 - Patients admitted to study sites with carefully defined criteria for acute liver failure and who are thought not to have acetaminophen toxicity, mushroom poisoning, pregnancy-related liver failure, or malignancy will be eligible. Each patient will...

Acetaminophen Biomarkers
https://clinicaltrials.gov/ct2/show/NCT01005173

Nov 24th, 2017 - This study is a non-intervention, multicenter study to address biomarkers of acetaminophen toxicity in children. Specifically, the study will examine acetaminophen (APAP) protein adducts and markers of liver injury in the blood samples of hospital...

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News  14 results

Fast Five Quiz: Acetaminophen
https://www.medscape.com/viewarticle/954960

Jul 22nd, 2021 - Acetaminophen is one of the most commonly used oral analgesic and antipyretic agents, with as many as 23% of US adults using an acetaminophen-containing medicine each week. It has an excellent safety profile when administered in proper therapeutic...

Acute Liver Failure in a 64-Year-Old Man
https://reference.medscape.com/viewarticle/911040_5

Mar 29th, 2019 - Various treatment protocols for acetaminophen toxicity are available, depending on the institution and the poison control center. For intravenous treatment (used in pregnant women, altered mental status, acetaminophen-induced liver failure, and in...

The Evolving Role of Opioids in Managing Chronic Pain
https://www.staging.medscape.com/viewarticle/879009_4

May 1st, 2017 - Deterring Abuse: What Works Medscape: There have been several efforts to deter abuse. How effective have such things as prescription monitoring programs and abuse-deterrent formulations been? Dr Chou: The prescription monitoring programs have cert...

VIDEO: Point-of-care assay caught acetaminophen toxicity
https://www.mdedge.com/internalmedicine/article/132476/hepatology/video-point-care-assay-caught-acetaminophen-toxicity
Amy Karon

Mar 1st, 2017 - A rapid point-of-care assay for acetaminophen-related liver toxicity had a sensitivity of 100% and a specificity of 86%, compared with etiologic diagnosis, based on the results of a multicenter study published in the April issue of Clinical Gastro.

Acetaminophen Liver Failure Least Likely to Get Transplant
https://www.mdedge.com/internalmedicine/article/56694/gastroenterology/acetaminophen-liver-failure-least-likely-get
Jeff Evans

Nov 12th, 2012 - BOSTON – Acetaminophen toxicity is the most frequent cause of acute liver failure in the United States and its usually milder presentation, along with comorbid psychosocial issues, explain why fewer patients with the etiology undergo liver transpl.

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Patient Education  1 results see all →