About 1,213 results

ALLMedicine™ Hyperammonemia Center

Research & Reviews  447 results

A systemic mechanism of increased transendothelial migration of leukocytes through the ...
Clinics and Research in Hepatology and Gastroenterology; Schaeffer A, Journaux M et. al.

Sep 14th, 2021 - Hepatic encephalopathy (HE) is a frequent neurological complication of cirrhosis. Evidence suggests a synergic pathophysiological implication of hyperammonemia and systemic inflammation. In addition, the blood-brain barrier (BBB) permeability can ...

NBAS deficiency due to biallelic c.2809C > G variant presenting with recurrent acute li...
https://doi.org/10.1007/s11011-021-00827-z 10.1016/j.bone.2016.10.023 10.1016/j.ejmg.2015.11.005 10.1016/j.ajhg.2015.05.009 10.1186/s12876-017-0636-3 10.2165/00148581-200709030-00008 10.1007/s10545-015-9896-7 10.1038/s41436-019-0698-4 10.1016/j.ejmg.2020.104039
Metabolic Brain Disease; Lipiński P, Greczan M et. al.

Aug 25th, 2021 - Biallelic pathogenic variants in the neuroblastoma amplified sequence (NBAS) gene were firstly (2015) identified as a cause of fever-triggered recurrent acute liver failure (RALF). Since then, some patients with NBAS deficiency presenting with neu...

Nonhepatic hyperammonemic encephalopathy complications following bariatric surgery: a c...
Journal of Medical Case Reports; Vinegrad N, Staretz-Chacham O et. al.

Jul 21st, 2021 - Hyperammonemic encephalopathy, a rare but fatal condition, is increasingly being reported as a possible complication of bariatric surgery. Here, we present a case of hyperammonemic encephalopathy, focusing on the clinical presentation, diagnostic ...

Lethal hyperammonemia in a CAR-T cell recipient due to Ureaplasma pneumonia: a case rep...
BMJ Case Reports; Tawfik P, Arndt P

Jul 11th, 2021 - We report the first incidence of Ureaplasma infection causing lethal hyperammonemia in a chimeric receptor antigen T cell (CAR-T) recipient. A 53-year-old woman, after receiving CAR-T therapy, suffered sepsis and encephalopathy. She was found to h...

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Guidelines  1 results

Extracorporeal treatment for valproic acid poisoning: systematic review and recommendat...
Clinical Toxicology (Philadelphia, Pa.); Ghannoum M, Laliberté M et. al.

May 8th, 2015 - The EXtracorporeal TReatments In Poisoning (EXTRIP) workgroup presents its systematic review and clinical recommendations on the use of extracorporeal treatment (ECTR) in valproic acid (VPA) poisoning. The lead authors reviewed all of the articles...

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Drugs  22 results see all →

News  15 results

Hyperammonemia in Children With Kidney Replacement Therapy Clinical Practice Guidelines (2020)

May 29th, 2020 - In April 2020, the Pediatric Continuous Renal Replacement Therapy Workgroup published their recommendations for the management of hyperammonemia in pediatric patients receiving continuous kidney replacement therapy.[1] Medical Therapy for Hyperamm...

Microbiome – Impact on health and disease
Gary D. Wu, MD

Jul 15th, 2019 - The gut microbiota influences our biology through our mucosal immune system as well as by leading to the production of bioactive small molecules. I’ll describe how gut microbiota influences colon cancer, liver disease, the production of bioactive.

Winners all

Dec 3rd, 2018 - Case Report Slide Winners Ze Ying Tan: All that wheezes is not asthma Jason Lam: Pulmonary mucor mycetoma Adam Young: Nonresolving pneumonia and cyclic fevers in an immunocompetent patient Ritu Modi: Histopathological misdiagnosis of pulmonary coc.

Rising microbiome investigator: Ting-Chin David Shen, MD, PhD

Sep 28th, 2018 - We spoke with Dr. Shen, instructor of medicine at the University of Pennsylvania and the recipient of the AGA Research Foundation’s 2016 Microbiome Junior Investigator Award, to learn about his passion for gut microbiome research.

Rare Disease Treatments Make Up Top 10 Most Costly Drugs

May 2nd, 2017 - UPDATED May 4, 2017 // The world's top 10 most expensive drugs are all orphan drugs for rare and ultrarare diseases, according to a new analysis. Leading that pack at number 1 is glycerol phenylbutyrate (Ravicti, Horizon Pharma), an orphan drug ap...

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